# Good Molecules Niacinamide Serum for oily acne-prone skin

**Lovi Fit: Average fit for oily acne-prone skin.**
Oily Skin Fit: Superior · Effectiveness: Average · Safety: Excellent.

Page: https://lovi.care/skincare/p/good-molecules/niacinamide-serum/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Good Molecules](https://lovi.care/skincare/brands/good-molecules)
Category: [Serums and treatments](https://lovi.care/skincare/best/serums)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily acne-prone skin; other serums fit it better.

## Why this fit

- Offers moderate pore decongestion and oil control for your oily skin, as niacinamide helps regulate sebum production and reduce inflammation. Glycerin also provides humectant action to maintain skin hydration.
- This serum provides moderate benefits for your acne and blemishes by improving skin texture and reducing the appearance of blemishes.
- The safety profile is excellent, with no risks of irritation for your oily skin due to the absence of harsh ingredients and the presence of soothing components like niacinamide.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/good-molecules/niacinamide-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/p/good-molecules/niacinamide-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/p/good-molecules/niacinamide-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/p/good-molecules/niacinamide-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/p/good-molecules/niacinamide-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/p/good-molecules/niacinamide-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/p/good-molecules/niacinamide-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/p/good-molecules/niacinamide-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/p/good-molecules/niacinamide-serum/for/oily-acne-prone-skin): Average (this page)

## Key ingredients

Niacinamide, Glycerin, Dipropylene Glycol, Betaine, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical treatment of nicotinamide, alone or in combination with other active ingredients, reduces the progression of skin aging and hyperpigmentation in clinical trials while being well tolerated. ([Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical dry mouth products containing olive oil, betaine, and xylitol significantly increased unstimulated whole salivary flow rates, reduced xerostomia complaints, and improved quality of life in adults with polypharmacy-induced xerostomia compared to their normal routine care, with no clinically significant adverse events. ([Journal of Oral Rehabilitation, 2007](https://pubmed.ncbi.nlm.nih.gov/17824884/))
- Soaps containing betaine caused the least skin irritation compared to other tested soaps in twenty-eight healthy subjects, though irritation did not decrease with increasing concentrations of betaine. ([Skin Research and Technology, 2003](https://pubmed.ncbi.nlm.nih.gov/12535284/))
- A combination of Aloe barbadensis leaf extract and trimethylglycine in a 1:1 mass ratio synergistically increased aquaporin 3 expression by up to 380% in keratinocytes and safely improved skin hydration in healthy volunteers. ([Molecules, 2024](https://pubmed.ncbi.nlm.nih.gov/38611819/))

## What reviewers say

Based on a very large amount of data, this serum is highly regarded for its lightweight, non-sticky feel and its effectiveness in visibly reducing pores and smoothing skin texture, all at an accessible price. Many users found it beneficial for controlling oil and redness. A smaller number of users reported experiencing breakouts or irritation, indicating it might not be suitable for all sensitive skin types.

- Liked: Affordable price (mostly mentioned)
- Liked: Improves texture (often mentioned)
- Liked: Minimizes pores (often mentioned)
- Liked: Controls oil/redness (sometimes noted)
- Liked: Elegant texture (sometimes noted)
- Disliked: Caused breakouts (sometimes noted)
- Disliked: No visible results (rarely noted)
- Disliked: Packaging issues (rarely noted)
- Disliked: Skin irritation (rarely noted)

## How to apply

- Could be used as part of your PM routine. Start 3 times a week and build up to daily use if your skin tolerates it well.
- Apply your serum after cleansing and toning, but before putting on your moisturizer.
- Gently press 2 to 3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on clean, dry skin to help manage your blemishes safely.
- Do a patch test before your first use and avoid the delicate eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Good Molecules Niacinamide work for oily acne-prone skin?

Good Molecules Niacinamide Serum is a moderate fit for your oily acne-prone skin because it helps control excess oil and reduces the look of blemishes, though other products fit your skin better. It has an excellent safety profile and is unlikely to cause irritation. Oily acne-prone skin needs products with effective ingredients like niacinamide, propolis, or Vitamin C, along with soothing extracts and lightweight hydrators that manage oil and texture without feeling heavy or causing breakouts.
Sources: [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Which ingredients make this serum a good fit for oily acne-prone skin?

Niacinamide and glycerin make this serum a good fit for oily acne-prone skin because niacinamide helps control oil and calm inflammation while glycerin maintains hydration. To fit this skin type even better, products need extra targeted ingredients like propolis or vitamin C for enhanced blemish control and antioxidant support.
Sources: [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Niacinamide do for oily acne-prone skin?

Niacinamide helps balance oil production, calms redness, and is unlikely to irritate oily, acne-prone skin while improving blemishes. Clinical tests show it reduces excess oil and helps clear up both inflammatory and non-inflammatory acne breakouts.
Sources: [Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38299457/)

### What does Glycerin do for oily acne-prone skin?

Glycerin helps keep oily acne-prone skin hydrated without feeling heavy. It draws moisture into the skin while supporting the skin barrier so it stays soft and balanced.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Where does this serum go in a skincare routine for oily acne-prone skin?

This serum goes in your evening routine after cleansing and before moisturizing, though some serums can also be used in the morning or twice a day. It is unlikely to irritate your oily skin because it lacks harsh ingredients and includes soothing components like niacinamide.
Sources: [International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/31461548/)

### Can I use this serum with retinol, and in what order?

Yes, you can use this serum with retinol by applying the serum before your retinol product. This helps keep your oily skin hydrated and calm while minimizing any dryness or irritation. An oil-controlling treatment with niacinamide and soothing ingredients is best for this routine.

### How often should I use this serum?

Use this serum in your evening routine, applying it after your cleansing toner and before your moisturizer. Oily acne-prone skin needs a treatment that combines stronger oil-controlling actives and pore-clearing ingredients to get a better fit.

### Can this serum clog pores, cause breakouts or purging for oily acne-prone skin?

This serum may cause breakouts for oily acne-prone skin, as some reviewers complain about this issue. However, the safety profile is otherwise good with a low risk of irritation due to soothing components like niacinamide.
Sources: [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily acne-prone skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/oily-acne-prone-skin) — Superior fit — $16.75 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/p/neogen-dermalogy/real-vitamin-c-serum/for/oily-acne-prone-skin) — Superior fit — $25.08 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/p/neogen-dermalogy/real-vita-c-serum/for/oily-acne-prone-skin) — High fit — $25.08 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/p/cerave/foaming-facial-cleanser/for/oily-acne-prone-skin) — Superior fit — $15.97 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — $25.60 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-acne-prone-skin) — Superior fit — $18.99 at Amazon

## Where to buy

- Amazon.com: $5.97 (https://www.amazon.com/dp/B08R994Q1L?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Niacinamide, Dipropylene Glycol, Glycerin, 1,2-Hexanediol, Betaine, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Xanthan Gum, Ethylhexylglycerin, Polysorbate 60, Sorbitan Isostearate, Diphenyl Dimethicone, Disodium Edta, Triethylhexanoin, Polyglyceryl-10 Oleate, Hydrogenated Lecithin, Phenoxyethanol, Chlorphenesin, Caprylyl Glycol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/good-molecules/niacinamide-serum/for/oily-acne-prone-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/good-molecules/niacinamide-serum/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/good-molecules/niacinamide-serum/for/oily-acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/good-molecules/niacinamide-serum/for/oily-acne-prone-skin
- France: https://lovi.care/skincare/fr/p/good-molecules/niacinamide-serum/for/oily-acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/good-molecules/niacinamide-serum/for/oily-acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/good-molecules/niacinamide-serum/for/oily-acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/good-molecules/niacinamide-serum/for/oily-acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/good-molecules/niacinamide-serum/for/oily-acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/good-molecules/niacinamide-serum/for/oily-acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/good-molecules/niacinamide-serum/for/oily-acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/good-molecules/niacinamide-serum/for/oily-acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/good-molecules/niacinamide-serum/for/oily-acne-prone-skin