# FATION NOSCA9 TROUBLE SERUM for sensitive skin

**Lovi Fit: Average fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/p/fation/nosca9-trouble-serum/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [FATION](https://lovi.care/skincare/brands/fation)
Category: [Serums and treatments](https://lovi.care/skincare/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for sensitive skin; other serums fit it better.

## Why this fit

- Offers moderate treatment for your redness and irritation, as Artemisia Princeps Leaf Extract and Centella Asiatica Extract help reduce inflammation and blemishes, while Glycerin and Hyaluronic Acid provide essential hydration for your normal skin.
- Panthenol and Centella Asiatica Extract offer supportive benefits for redness and irritation, complementing the humectant action of Glycerin and Hyaluronic Acid.
- The product is safe for your sensitive skin, containing soothing ingredients like Artemisia Princeps Leaf Extract and Centella Asiatica Extract with no harsh or prohibited substances.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/fation/nosca9-trouble-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/p/fation/nosca9-trouble-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/p/fation/nosca9-trouble-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/p/fation/nosca9-trouble-serum/for/sensitive-skin): Average (this page)
- [Acne-prone skin](https://lovi.care/skincare/p/fation/nosca9-trouble-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/p/fation/nosca9-trouble-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/p/fation/nosca9-trouble-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/p/fation/nosca9-trouble-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/p/fation/nosca9-trouble-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Artemisia Princeps Leaf Extract, Glycerin, Panthenol

## What the research says

- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Isosecotanapartholide (ISTP) isolated from Artemisia princeps Pampanini extract downregulated STAT-1 expression, reduced IL-33 production, and inhibited TARC/CCL17 mRNA and ICAM-1 protein expression in human keratinocytes stimulated by tumor necrosis factor-alpha/interferon-gamma. ([Molecular Medicine Reports, 2017](https://pubmed.ncbi.nlm.nih.gov/28447741/))
- Artemisia princeps-derived nanovesicles accelerate cell proliferation, decrease senescence-associated beta-galactosidase activity, inhibit MMP-1 activity more effectively than EGCG, and increase procollagen type I expression in human dermal cells and skin models. ([Journal of Extracellular Biology, 2025](https://pubmed.ncbi.nlm.nih.gov/40292385/))
- Artemisia annua aqueous extract increased the itching threshold, inhibited TSLP expression, and promoted FLG mRNA expression in in vitro and in vivo models. ([Journal of Ethnopharmacology, 2024](https://pubmed.ncbi.nlm.nih.gov/37604330/))
- Artemisia Capillaris Thunb. extract protects human HaCaT keratinocytes from UVB-induced apoptosis and inflammation by suppressing the cGAS/STING signaling pathway. ([Journal of Photochemistry and Photobiology. B, Biology, 2024](https://pubmed.ncbi.nlm.nih.gov/39032373/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two. ([Auris, Nasus, Larynx, 2020](https://pubmed.ncbi.nlm.nih.gov/32067777/))

## What reviewers say

Based on a very large amount of data, this serum is widely praised by users with acne-prone and sensitive skin for its ability to rapidly calm redness and inflammation without clogging pores. While it is not an overnight miracle cure for active breakouts, consistent use strengthens the skin barrier and significantly reduces the severity and duration of hormonal acne and irritation.

- Liked: Lightweight & fast absorbing (mostly mentioned)
- Liked: Rapidly calms redness (mostly mentioned)
- Liked: Improves barrier health (often mentioned)
- Liked: Non-comedogenic (often mentioned)
- Disliked: Not moisturizing enough (sometimes noted)
- Disliked: Price point (sometimes noted)
- Disliked: Slight stickiness (rarely noted)
- Disliked: Slow results on acne (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does FATION NOSCA9 Trouble Serum work for sensitive skin?

FATION NOSCA9 Trouble Serum works moderately well for sensitive skin, helping calm redness and irritation with Artemisia Princeps Leaf Extract and Centella Asiatica Extract while providing basic moisture with Glycerin and Hyaluronic Acid. To fit sensitive skin even better, a treatment of this type needs highly compatible soothing extracts, niacinamide, and snail secretion filtrate to deliver optimal redness relief without irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Which ingredients make this serum a good fit for sensitive skin?

Artemisia Princeps Leaf Extract, Glycerin, Panthenol, Hyaluronic Acid, and Centella Asiatica Extract make this serum a good fit because they help calm redness and irritation while providing essential hydration. To fit sensitive skin even better, this type of product needs extra skin-repairing and antioxidant ingredients like niacinamide and snail secretion filtrate.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### What does Mugwort Leaf Extract do for sensitive skin?

Mugwort leaf extract helps calm sensitive skin by lowering irritation and strengthening the skin barrier to keep it soft and comfortable. This ingredient supports natural proteins that protect dry or irritated skin, making it feel smooth and less reactive.
Sources: [Molecular Medicine Reports, 2017](https://pubmed.ncbi.nlm.nih.gov/28447741/), [International Journal of Molecular Sciences, 2017](https://pubmed.ncbi.nlm.nih.gov/28892018/)

### What does Glycerin do for sensitive skin?

Glycerin helps keep sensitive skin soft and deeply hydrated while supporting the skin barrier. It is unlikely to cause irritation and may protect against dryness and roughness.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [Acta Dermato-venereologica, 1999](https://pubmed.ncbi.nlm.nih.gov/10598752/)

### Where does this serum go in a skincare routine for sensitive skin?

This serum goes in the evening routine after cleansing and toning, as treatments with active ingredients are placed at night for safety and simplicity. Sensitive skin needs a product that offers gentle blemish care and redness relief along with essential hydration.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to calm your skin and provide hydration, followed by your retinol. This treatment helps reduce irritation, but sensitive skin needs a product that also delivers deeper soothing ingredients like Centella Asiatica Extract and panthenol for a better fit.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### How often should I use this serum?

You can use this treatment in the evening as part of your routine, and some serums can also be used in the morning or twice a day if your skin tolerates them well. A product for sensitive skin needs soothing ingredients like Centella Asiatica Extract and gentle moisturizers like Glycerin to calm redness and keep skin smooth.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Can this serum clog pores, cause breakouts or purging for sensitive skin?

This serum is unlikely to clog pores or cause breakouts for your sensitive skin, as it contains soothing ingredients like Artemisia Princeps Leaf Extract and Centella Asiatica Extract with no harsh or heavy substances. A product of this type needs lightweight hydration ingredients like glycerin and hyaluronic acid to keep pores clear while calming your skin.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for sensitive skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/sensitive-skin) — Superior fit — $53.00 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/p/skinceuticals/c-e-ferulic/for/sensitive-skin) — High fit — $39.99 at Amazon
- [Clarins Double Serum](https://lovi.care/skincare/p/clarins/double-serum/for/sensitive-skin) — High fit — $142.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — $28.08 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/p/clarins/soothing-toning-lotion/for/sensitive-skin) — Superior fit — $28.05 at Amazon
- Moisturizer with Sun Protection: [innisfree Daily Mild Sunscreen](https://lovi.care/skincare/p/innisfree/daily-mild-sunscreen/for/sensitive-skin) — Superior fit — $18.00 at Amazon

## Where to buy

No store in United States has a checked price for this product, so the page shows none.

## Ingredients

Artemisia Princeps Leaf Extract, Water, Glycerin, Dipropylene Glycol, Panthenol, 1,2-Hexanediol, Pentylene Glycol, Hyaluronic Acid, Diethoxyethyl Succinate, Hydroxyethyl Urea, Acrylates C10-30 Alkyl Acrylate Cross Polymer, Ammonium Acryloyldimethyltaurate Vp Copolymer, Tromethamine, Allantoin, Centella Asiatica Extract, Hydroxyacetophenone, Ethylhexylglycerin, Polyglyceryl-10 Laurate, Succinic Acid, Xanthan Gum, Sodium Heparin, Pyrus Malus Fruit Extract, Tocopherol, Caprylyl Capryl Glucoside, Hydrogenated Lecithin, Ceramide Np
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/fation/nosca9-trouble-serum/for/sensitive-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/fation/nosca9-trouble-serum/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/fation/nosca9-trouble-serum/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/fation/nosca9-trouble-serum/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/fation/nosca9-trouble-serum/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/fation/nosca9-trouble-serum/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/fation/nosca9-trouble-serum/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/fation/nosca9-trouble-serum/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/fation/nosca9-trouble-serum/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/fation/nosca9-trouble-serum/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/fation/nosca9-trouble-serum/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/fation/nosca9-trouble-serum/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/fation/nosca9-trouble-serum/for/sensitive-skin