Eucerin Sun Gel-crema Oil Control FPS 50+ for oily acne-prone skin

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Questions and answers

What the research says

• Application of a skin care formulation containing licochalcone A, l-carnitine and 1,2-decanediol twice daily for 8 weeks reduced total lesion count, papules, pustules, P. acnes colonization, and sebum levels while improving life quality in volunteers with mild to moderately severe acne compared to a vehicle control.

  Journal of the European Academy of Dermatology and Venereology, 2013

• A moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid significantly reduced noninflammatory, inflammatory, and total acne lesion counts compared to a vehicle control in Thai patients during a 12-week maintenance phase.

  BioMed Research International, 2020

• The concomitant usage of adapalene gel and a moisturizer containing licochalcone A, l-carnitine and 1,2-decanediol reduced undesirable skin irritations and lowered inflammatory and total lesions compared to adapalene alone or with placebo in Asian subjects with mild to moderate severe acne.

  The Journal of Dermatological Treatment, 2016

• Chemical sunscreens containing avobenzone, octocrylene, homosalate, and octisalate showed no to minimal risks of dermal irritation, sensitization, photo-allergy, and photo-irritation in human subjects.

  Journal of Drugs in Dermatology, 2025

• The topical application of a combination of the TRPV1 antagonist 4-t-butylcyclohexanol and the anti-inflammatory licochalcone A provided an effective treatment for sensitive skin, resulting in immediate relief from symptoms such as erythema, stinging, and burning.

  Journal of the European Academy of Dermatology and Venereology, 2016

• Dermal application of a sunscreen containing 10% homosalate in four volunteers resulted in delayed elimination with terminal half-times around 24 h and a bioavailability of cis-homosalate a factor of 2 lower than trans-homosalate, while metabolite ratios supported using oral-route urinary excretion fractions for dermal exposure assessments.

  Archives of Toxicology, 2024

• Homosalate exhibited the highest permeation among tested filters with a relative permeability rate of 4.2% and a depth of 60 um, and specific thickeners and emulsifiers successfully reduced its permeation without inhibiting the skin permeation of niacinamide.

  Photodermatology, Photoimmunology & Photomedicine, 2026

• An online-SPE-LC-MS/MS method successfully quantified specific urinary homosalate metabolites for up to 96 hours after dermal sunscreen application in a volunteer and detected metabolites exclusively in three German pilot participants who had used sunscreen within five days.

  Analytica Chimica Acta, 2021

• Encapsulation of ethylhexyl methoxycinnamate and butyl methoxydibenzoylmethane in lipid microparticles significantly reduced their in vivo human skin penetration compared to nonencapsulated filters.

  Skin Pharmacology and Physiology, 2011

• Microencapsulation of the BMDBM/HP-beta-CD complex in lipid microparticles significantly decreased the percutaneous penetration of the UV filter into the stratum corneum of human volunteers compared to the non-encapsulated sunscreen agent.

  Journal of Pharmaceutical and Biomedical Analysis, 2011

• Following human skin application of an O/W emulsion containing 2% BMDBM loaded in lipospheres, 15% of the sunscreen accumulated in the uppermost layers of the stratum corneum without remarkably modifying skin permeation compared to unencapsulated sunscreen.

  Skin Pharmacology and Physiology, 2008

• A topical sunscreen containing octyl triazone, phenylbenzimidazole sulfonic acid, and methylbenzylidene camphor prevented UVB-induced suppression of intercellular adhesion molecule-1 expression and mixed-lymphocyte reaction in epidermal cell cultures compared to control sunscreens with comparable SPF lacking octyl triazone.

  Toxicology in Vitro, 1994

• Combining 755 nm alexandrite laser with topical licorice gel significantly reduces terminal hair counts compared to alexandrite laser with placebo in women with idiopathic hirsutism.

  Evidence-based Complementary and Alternative Medicine, 2015

• Licochalcone A activated Nrf2 signaling, elevated cytoprotective enzymes, increased the reduced-to-oxidized glutathione ratio, and decreased reactive oxygen species in human fibroblasts and neutrophils, while a LicA-rich licorice extract lowered UVA-induced oxidative processes in vivo.

  Experimental Dermatology, 2015

• Bioactive glycyrrhizic acid and oxymatrine ionic liquid self-assembled nanomicelles significantly promoted the transdermal permeation, subcutaneous retention, and anti-photoaging efficacy of palmitoyl pentapeptide-4 in cellular and animal models compared to unformulated peptide.

  Advanced Science, 2025

Ingredients

Water, Homosalate, Polymethylsilsesquioxane, Butyl Methoxydibenzoylmethane, Ethylhexyl Salicylate, Octocrylene, Alcohol Denat, Tapioca Starch, Phenylbenzimidazole Sulfonic Acid, Cyclomethicone, Behenyl Alcohol, Cetearyl Alcohol, Menthoxypropanediol, Silica Dimethyl Silylate, Glycerin, Carnitine, Acid Gliciretinic, Glycyrrhiza Inflata Root Extract, Sodium Stearoyl Glutamate, Acrylates-C10-30-Alkyl-Acrylate-Crosspolymer, Carbomer, Xanthan Gum, Sodium Hydroxide, Sodium Chloride, Trisodium Edta, Ethylhexylglycerin, Phenoxyethanol

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.