# Eucerin Hyaluron-Filler Epigenetic Serum for oily skin

**Lovi Fit: Low fit for oily skin.**
Oily Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/p/eucerin/hyaluron-filler-epigenetic-serum/for/oily-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Eucerin](https://lovi.care/skincare/brands/eucerin)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/best/moisturizers)

This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A weak match for oily skin; the moisturizers alongside fit it better.

## Why this fit

- Offers moderate moisturizing for your oily skin due to glycerin and hyaluronic acid, which hydrate without exacerbating oiliness, but does not directly address the main goal of reducing oily shine.
- Glyceryl glucoside and panthenol provide additional hydration and support, though the formula lacks ingredients specifically targeting oil reduction.
- The safety profile is excellent, with no risks of irritation for your oily skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/eucerin/hyaluron-filler-epigenetic-serum/for/oily-skin): Low (this page)
- [Dry skin](https://lovi.care/skincare/p/eucerin/hyaluron-filler-epigenetic-serum/for/dry-skin): Warning
- [Combination skin](https://lovi.care/skincare/p/eucerin/hyaluron-filler-epigenetic-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/p/eucerin/hyaluron-filler-epigenetic-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/p/eucerin/hyaluron-filler-epigenetic-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/p/eucerin/hyaluron-filler-epigenetic-serum/for/dark-spots): Low
- [Mature skin](https://lovi.care/skincare/p/eucerin/hyaluron-filler-epigenetic-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/p/eucerin/hyaluron-filler-epigenetic-serum/for/dry-sensitive-skin): Caution
- [Oily acne-prone skin](https://lovi.care/skincare/p/eucerin/hyaluron-filler-epigenetic-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Glycerin, Hyaluronic Acid

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- Topical application of glyceryl glucoside significantly increased AQP3 mRNA levels and reduced transepidermal water loss compared with vehicle-controlled areas in volunteer subjects. ([Skin Pharmacology and Physiology, 2012](https://pubmed.ncbi.nlm.nih.gov/22584263/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## Why other moisturizers fit oily skin better

- Gluconolactone chemical peels lower skin pH and transepidermal water loss while demonstrating seboregulatory properties in 16 female subjects. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37335807/))
- Combining 10% gluconolactone chemical peeling with oxybrasion or microneedle mesotherapy increased skin hydration and decreased sebum, pH, and TEWL in twenty-one Caucasian women, with no significant differences between the two methods. ([Skin Research and Technology, 2023](https://pubmed.ncbi.nlm.nih.gov/37357656/))
- A peel-off facial mask containing myoinositol and trehalose-loaded liposomes improved adult female acne by decreasing lesion counts, sebum production, GAGS scores, and local androgen levels while increasing beclin-1 levels. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28342238/))

## What reviewers say

Based on a very large amount of data, users consistently report that the serum provides an immediate boost of hydration, leaving skin feeling significantly smoother, softer, and more radiant. While many observed a reduction in fine lines and a "plumped" effect within a few weeks, a small minority experienced skin irritation or felt the anti-aging results were not visible enough to justify the price.

- Liked: Lightweight, fast absorption (mostly mentioned)
- Liked: Layers well (often mentioned)
- Liked: Smoother, plumper skin (often mentioned)
- Liked: Pleasant, subtle scent (sometimes noted)
- Liked: Radiant, fresh glow (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Allergic reactions (rarely noted)
- Disliked: No visible results (rarely noted)
- Disliked: Scent too strong (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine every day to keep your face fresh.
- Apply this moisturizer after cleansing and toning, but right before your SPF in the morning.
- Gently press a small amount into your skin and let it absorb fully.
- Apply on clean, slightly dry skin to help control that oily shine.
- Avoid the eye area and do a quick patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### Why is Eucerin Hyaluron-Filler Epigenetic Serum a weak match for oily skin?

This product is a weak match because it offers only moderate hydration from glycerin and hyaluronic acid without directly reducing oily shine. An oily skin treatment needs ingredients like niacinamide to help regulate oil production and minimize the appearance of pores while keeping the skin balanced.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a poor fit for oily skin?

This serum is a weak match for oily skin because it lacks ingredients like niacinamide that actively reduce oily shine and pore size, even though its glycerin and hyaluronic acid provide light hydration without adding greasiness. Oily skin of this type needs a formula with niacinamide to control oil, alongside soothing allantoin and lightweight hydrators.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Water do for oily skin?

Water helps keep oily skin hydrated without adding grease or clogging pores. Keeping oily skin properly hydrated may also help balance oil production and reduce unwanted shine.

### What does Glycerin do for oily skin?

Glycerin helps keep oily skin hydrated without feeling heavy and supports the skin barrier. Because this product is a weak fit for your skin, an ideal product of this type needs lightweight hydrators and ingredients that balance oil while protecting the skin.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [International Journal of Toxicology, 2019](https://pubmed.ncbi.nlm.nih.gov/31840548/)

### Where does this serum go in a skincare routine for oily skin?

This treatment goes in your evening routine after cleansing and before your moisturizer. It is unlikely to irritate your oily skin because it lacks harsh ingredients, though a product for this skin also needs specific ingredients to reduce oily shine.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol, applying the serum before your retinol product to help keep your skin comfortable and hydrated. This formula is unlikely to cause irritation on oily skin, but an oily skin type also needs ingredients that help reduce shine and balance oil production.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### How often should I use this serum?

Apply this treatment in the evening as part of your routine. This product offers moderate hydration for your oily skin, though an oily skin routine of this type needs ingredients that target oil reduction.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this serum clog pores, cause breakouts or purging for oily skin?

This serum is unlikely to cause irritation or breakouts on oily skin due to its safe ingredients and lack of harsh components. However, because it only offers moderate hydration without targeting oily shine, oily skin typically needs lightweight, oil-free formulas with ingredients that help control excess oil.

### Can I use this serum around the eyes or on my body?

This moisturizing treatment can be used around the eyes and on the body, as its gentle ingredients like glycerin, hyaluronic acid, panthenol, and glyceryl glucoside help hydrate thin or dry areas safely without irritation. Because skin thickness varies greatly across different body regions, formulas with soothing and hydrating components like panthenol are well tolerated in delicate areas.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Is this serum fragrance-free and alcohol-free?

It contains fragrance (parfum) and drying alcohol (alcohol denat).

## Alternatives for oily skin

- [Elizavecca Witch Piggy Hell Pore Control Hyaluronic Acid 97%](https://lovi.care/skincare/p/elizavecca/witch-piggy-hell-pore-control-hyaluronic-acid-97/for/oily-skin) — High fit — $8.40 at Amazon
- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/oily-skin) — High fit — $22.25 at Amazon
- [COSRX Hydrium Triple Hyaluronic Moisture Ampoule](https://lovi.care/skincare/p/cosrx/hydrium-triple-hyaluronic-moisture-ampoule/for/oily-skin) — High fit — $19.99 at Amazon

## Routine for oily skin

### AM

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — $15.97 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — $15.60 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-skin) — Superior fit — $18.99 at Amazon
- SPF: [CeraVe AM Facial Moisturizing Lotion](https://lovi.care/skincare/p/cerave/am-facial-moisturizing-lotion-spf-30/for/oily-skin) — Superior fit — $14.97 at Amazon

### PM

- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/oily-skin) — Superior fit — $50.00 at Amazon
- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — $15.97 at Amazon
- Cleansing Toner: [Pixi Glow Tonic](https://lovi.care/skincare/p/pixi/glow-tonic/for/oily-skin) — Superior fit — $28.42 at Amazon
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/p/peach-and-lily/glass-skin-refining-serum/for/oily-skin) — Superior fit — $39.00 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-skin) — Superior fit — $18.99 at Amazon

### Weekly

- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/oily-skin) — Superior fit — $50.00 at Amazon
- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — $15.97 at Amazon
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — $69.00 at Amazon
- Cleansing Mask: [Revision Skincare Black Mask](https://lovi.care/skincare/p/revision-skincare/black-mask/for/oily-skin) — Superior fit — $79.00 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — $15.60 at Amazon
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/p/peach-and-lily/glass-skin-refining-serum/for/oily-skin) — Superior fit — $39.00 at Amazon

## Where to buy

No store in United States has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Alcohol Denat, Hyaluronic Acid, Epicelline, Panthenol, Glyceryl Glucoside, Sodium Hydroxide, Phenoxyethanol, Parfum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/eucerin/hyaluron-filler-epigenetic-serum/for/oily-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/eucerin/hyaluron-filler-epigenetic-serum/for/oily-skin
- Ireland: https://lovi.care/skincare/ie/p/eucerin/hyaluron-filler-epigenetic-serum/for/oily-skin
- Germany: https://lovi.care/skincare/de/p/eucerin/hyaluron-filler-epigenetic-serum/for/oily-skin
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- United Arab Emirates: https://lovi.care/skincare/ae/p/eucerin/hyaluron-filler-epigenetic-serum/for/oily-skin