# Derma E Hydrating Gentle Cleanser for mature skin

**Lovi Fit: Average fit for mature skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/p/derma-e/hydrating-gentle-cleanser/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Derma E](https://lovi.care/skincare/brands/derma-e)
Category: [Cleansers](https://lovi.care/skincare/best/cleansers)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for mature skin; other cleansers fit it better.

## Why this fit

- Suitable for normal skin, this cleanser contains sodium hyaluronate and panthenol vitamin b5 to provide humectant action and barrier repair, though it lacks specialized ingredients like peptides or retinoids to effectively target your wrinkles and fine lines.
- It offers moderate cleansing benefits due to the inclusion of Sodium Methyl Cocoyl Taurate and Cocamidopropyl Betaine, which help to effectively cleanse pores.
- The product is safe for your normal skin, with no risks of irritation from harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/derma-e/hydrating-gentle-cleanser/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/p/derma-e/hydrating-gentle-cleanser/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/p/derma-e/hydrating-gentle-cleanser/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/p/derma-e/hydrating-gentle-cleanser/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/p/derma-e/hydrating-gentle-cleanser/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/p/derma-e/hydrating-gentle-cleanser/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/p/derma-e/hydrating-gentle-cleanser/for/mature-skin): Average (this page)
- [Dry sensitive skin](https://lovi.care/skincare/p/derma-e/hydrating-gentle-cleanser/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/p/derma-e/hydrating-gentle-cleanser/for/oily-acne-prone-skin): High

## Key ingredients

Sodium Hyaluronate, Chamomile, Vitamin E, Carica Papaya Extract, Lemongrass Extract

## What the research says

- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- A topical antioxidant serum significantly reduced air pollution-induced skin pigmentation and proinflammatory gene expression ex vivo, and improved skin aging signs in 40 healthy adult females after 90 days of daily use. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35150043/))
- Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Apigenin protects against UVA-induced cytotoxicity and senescence in normal human dermal fibroblasts, decreases MMP-1 expression, and when applied topically as a cream in human subjects, increases dermal density and elasticity while reducing fine wrinkle length, skin evenness, moisture content, and transepidermal water loss compared to control cream. ([International Journal of Molecular Medicine, 2016](https://pubmed.ncbi.nlm.nih.gov/27279007/))
- Topical chamomile oil combined with a night splint significantly improved the symptomatic and functional status of patients with severe carpal tunnel syndrome compared to placebo, while electrodiagnostic parameters showed no significant changes. ([Complementary Therapies in Clinical Practice, 2015](https://pubmed.ncbi.nlm.nih.gov/26573447/))
- German chamomile solution applied twice a day healed peristomal skin lesions significantly faster than once-a-day 1% hydrocortisone ointment in colostomy patients, with a mean healing time of 8.89 days versus 14.53 days. ([Ostomy/wound Management, 2011](https://pubmed.ncbi.nlm.nih.gov/21617262/))
- Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40642809/))
- Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate. ([Contemporary Clinical Trials Communications, 2021](https://pubmed.ncbi.nlm.nih.gov/34471722/))
- Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590207/))
- Topical papain treatment may slightly decrease pain within 30 minutes in humans stung by Chrysaora chinensis compared to placebo. ([Wilderness & Environmental Medicine, 2016](https://pubmed.ncbi.nlm.nih.gov/26827260/))
- A fixed combination of hydroxypinacolone retinoate, retinol glycospheres, and papain glycospheres in aqueous gel applied once daily for 12 weeks achieved a 41% mean reduction in GAGS score and a 40.8% mean reduction in total lesions, with 15.3% of patients experiencing mild to moderate local side effects, in 94 evaluable patients with comedonal-papular, mild to moderate acne of the face. ([Giornale Italiano Di Dermatologia E Venereologia, 2015](https://pubmed.ncbi.nlm.nih.gov/25876142/))
- Reflux extraction of Carica papaya leaves yielded higher antioxidant capacity and superior in vitro wound-healing activities including fibroblast proliferation, cell migration, and collagen synthesis in human skin fibroblasts compared to ultrasonic-assisted extraction and agitation. ([Molecules, 2020](https://pubmed.ncbi.nlm.nih.gov/31991676/))
- A topical emulgel formulation containing lemongrass essential oil and olive oil showed good stability, a moderate SPF value of 5.5, and significant improvements in cooling effect, odor, smoothness, and moisture in 20 volunteers. ([Journal of Cosmetic Science, 2021](https://pubmed.ncbi.nlm.nih.gov/35349422/))
- Lemongrass essential oil treatment demonstrated similar efficacy to chlorhexidine and doxycycline in treating periodontitis, gingivitis, and oral malodour, while also showing potential for treating pityriasis versicolor, preventing skin aging, and providing anti-dandruff effects. ([Pharmaceuticals, 2024](https://pubmed.ncbi.nlm.nih.gov/38399374/))
- Lemon grass essential oil demonstrated in vitro antifungal activity against pathogenic yeasts and filamentous fungi alongside in vivo topical and oral anti-inflammatory effects in animal models. ([The Libyan Journal of Medicine, 2014](https://pubmed.ncbi.nlm.nih.gov/25242268/))

## Why other cleansers fit mature skin better

- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Treatment with a combination of niacinamide and hyaluronic acid improved skin aging signs and demonstrated a senomorphic effect by decreasing SASP and autocrine signaling genes in women. ([Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/))

## How to apply

- Use your cleanser as part of both your AM and PM routine. Start using it daily since your skin is normal and not sensitive.
- Apply this first in your routine before using your toner, moisturizer, and SPF.
- Gently massage the cleanser onto your face using circular motions, then rinse well with water. Avoid rubbing your skin too hard.
- Apply the cleanser directly onto slightly damp skin for the best fresh feeling. Make sure your face is clean of heavy makeup first.
- Avoid the sensitive eye area while washing. Do a quick patch test before your very first use to be safe.
- Video: https://storage.pora.ai/6a08416bd9315041c09c72f61cf27cc1.mp4

## Questions and answers

### How well does Derma-E Hydrating Gentle Cleanser work for mature skin?

This cleanser works well enough for mature skin by cleaning pores safely while keeping the skin soft with sodium hyaluronate and panthenol, though it lacks specialized ingredients like peptides or retinoids to target fine lines. To truly fit mature skin, this type of product needs extra ingredients that smooth lines and firm the skin while providing deep hydration.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Which ingredients make this cleanser a good fit for mature skin?

This cleanser is a fair fit for mature skin because it contains sodium hyaluronate and panthenol vitamin B5 to help keep skin hydrated and repair the skin barrier. However, a product of this type needs specialized ingredients like peptides or retinoids to effectively target fine lines and wrinkles for this skin type.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### What does Hyaluronic Acid do for mature skin?

Hyaluronic acid helps mature skin by deeply boosting moisture, improving elasticity, and smoothing the appearance of fine lines and wrinkles. Regular use keeps the skin looking plump and soft while supporting overall firmness and hydration.
Sources: [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/), [Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38591218/)

### What does Chamomile do for mature skin?

Chamomile helps smooth mature skin by reducing wrinkles, improving firmness, and keeping it soft and well-hydrated. It also has a strong safety profile and is unlikely to cause irritation while protecting against daily sun damage.
Sources: [International Journal of Molecular Medicine, 2016](https://pubmed.ncbi.nlm.nih.gov/27279007/), [Revista Latino-americana de Enfermagem, 2018](https://pubmed.ncbi.nlm.nih.gov/30517572/)

### Where does this cleanser go in a skincare routine for mature skin?

This cleanser goes in both your morning and evening routine, used right after removing makeup at night. A gentle cleanser helps keep your skin clean without irritation, though mature skin also needs specialized ingredients like peptides or retinoids in targeted treatments to smooth wrinkles and fine lines.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/)

### Can I use this cleanser with retinol, and in what order?

You can use this cleanser with retinol by applying the cleanser first, followed by your retinol treatment in your evening routine. This cleanser is safe for your skin with no risks of irritation, but it lacks ingredients like peptides or retinoids that actively target wrinkles and fine lines.

### How often should I use this cleanser?

You can use this cleanser daily in the morning and evening as part of your routine. A daily skincare routine with a mild cleanser and moisturizer helps improve skin condition and hydration.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/)

### Can this cleanser clog pores, cause breakouts or purging for mature skin?

This cleanser is unlikely to clog pores or cause breakouts for mature skin, as it contains gentle cleansing ingredients that effectively clear out pores without irritation. However, mature skin looking to target wrinkles and fine lines needs specialized ingredients like peptides or retinoids.

### Can I use this cleanser around the eyes or on my body?

Yes, you can safely use this cleanser on your body, but mature skin around the eyes needs a gentle formula with specialized ingredients like peptides or retinoids to target wrinkles and fine lines.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/)

### Is this cleanser fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for mature skin

- [SOME BY MI Snail Truecica Miracle Repair Low pH Gel Cleanser](https://lovi.care/skincare/p/some-by-mi/snail-truecica-miracle-repair-low-ph-gel-cleanser/for/mature-skin) — Superior fit — $13.40 at Amazon
- [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/mature-skin) — Superior fit — $19.99 at Amazon
- [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/p/cerave/foaming-facial-cleanser/for/mature-skin) — High fit — $15.97 at Amazon

## Pairs well with

- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — $17.00 at Amazon
- Moisturizer: [Obagi Hydrate Luxe Moisture-Rich Cream](https://lovi.care/skincare/p/obagi/hydrate-luxe/for/mature-skin) — Superior fit — $85.00 at Amazon
- SPF: [ISDIN Eryfotona Actinica SPF 50+](https://lovi.care/skincare/p/isdin/eryfotona-actinica-spf-50/for/mature-skin) — Superior fit — $46.00 at Amazon

## Where to buy

No store in United States has a checked price for this product, so the page shows none.

## Ingredients

Water, Sodium Methyl Cocoyl Taurate, Cocamidopropyl Hydroxysultaine, Cocamidopropyl Betaine, Disodium Laureth Sulfosuccinate, Glyceryl Laurate, Sodium Hyaluronate, Panthenol Vitamin B5, Tocopheryl Acetate Vitamin E, Retinyl Palmitate Vitamin A, Cymbopogon Schoenanthus Extract Lemongrass Extract, Equisetum Arvense Extract, Carica Papaya Fruit Extract, Chamomilla Recutita Flower Extract Matricaria Flower Extract, Allantoin, Potassium Sorbate, Phenoxyethanol, Ethylhexylglycerin, Oils
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/derma-e/hydrating-gentle-cleanser/for/mature-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/derma-e/hydrating-gentle-cleanser/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/derma-e/hydrating-gentle-cleanser/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/derma-e/hydrating-gentle-cleanser/for/mature-skin
- France: https://lovi.care/skincare/fr/p/derma-e/hydrating-gentle-cleanser/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/derma-e/hydrating-gentle-cleanser/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/derma-e/hydrating-gentle-cleanser/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/derma-e/hydrating-gentle-cleanser/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/derma-e/hydrating-gentle-cleanser/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/derma-e/hydrating-gentle-cleanser/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/derma-e/hydrating-gentle-cleanser/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/derma-e/hydrating-gentle-cleanser/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/derma-e/hydrating-gentle-cleanser/for/mature-skin