# Derma E Anti-Wrinkle Renewal Cream for oily acne-prone skin

**Lovi Fit: Average fit for oily acne-prone skin.**
Oily Skin Fit: High · Effectiveness: Average · Safety: Low Risk.

Page: https://lovi.care/skincare/p/derma-e/anti-wrinkle-renewal-cream/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Derma E](https://lovi.care/skincare/brands/derma-e)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/best/moisturizers)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily acne-prone skin; other moisturizers fit it better.

## Why this fit

- Offers moderate moisturizing and anti-aging effects for your oily skin, with retinol and glycerin working to hydrate and smooth texture, though bakuchiol's keratolytic action may be too strong for some.
- While it provides general skincare benefits, the inclusion of oils like Carthamus Tinctorius Seed Oil and Persea Gratissima Oil Avocado Oil may not be ideal for managing your acne, blemishes, and breakouts or oiliness.
- The product is generally safe for your oily skin, with a low risk of irritation from retinol.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/derma-e/anti-wrinkle-renewal-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/p/derma-e/anti-wrinkle-renewal-cream/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/p/derma-e/anti-wrinkle-renewal-cream/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/p/derma-e/anti-wrinkle-renewal-cream/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/p/derma-e/anti-wrinkle-renewal-cream/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/p/derma-e/anti-wrinkle-renewal-cream/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/p/derma-e/anti-wrinkle-renewal-cream/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/p/derma-e/anti-wrinkle-renewal-cream/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/p/derma-e/anti-wrinkle-renewal-cream/for/oily-acne-prone-skin): Average (this page)

## Key ingredients

Retinol, Bakuchiol, Panthenol Vitamin B5, Tocopheryl Acetate Vitamin E, Carthamus Tinctorius Seed Oil

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))
- Topical stabilized retinol treatment induced HAS gene expression and increased hyaluronic acid production in human skin in vitro, ex vivo, and in vivo compared to vehicle. ([Archives of Dermatological Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28247017/))
- A dermocosmetic containing bakuchiol, Ginkgo biloba extract, and mannitol improves inflammatory lesions, Investigator Global Assessment, and seborrhea intensity when added to adapalene 0.1% gel in patients with acne vulgaris. ([Clinical, Cosmetic and Investigational Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25914553/))
- Topical application of a serum containing supramolecular Bakuchiol and Terminalia chebula extract significantly improved barrier function, reduced redness and sensitivity, and improved wrinkles and elasticity in 34 Chinese subjects with sensitive skin after 28 days. ([Health Science Reports, 2025](https://pubmed.ncbi.nlm.nih.gov/41424674/))
- Bakuchiol functions as an anti-aging compound through retinol-like regulation of gene expression, producing significant improvements in lines, wrinkles, pigmentation, elasticity, firmness, and photo-damage after 12 weeks of twice-a-day facial application without usual retinol therapy-associated undesirable effects. ([International Journal of Cosmetic Science, 2014](https://pubmed.ncbi.nlm.nih.gov/24471735/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40642809/))
- Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate. ([Contemporary Clinical Trials Communications, 2021](https://pubmed.ncbi.nlm.nih.gov/34471722/))
- Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590207/))
- Safflower oil body-human epidermal growth factor microgel emulsions mixed with xanthan gum enhance transdermal absorption, regulate inflammation, accelerate angiogenesis, and promote re-epithelialization and remodeling in full-layer skin wounds in rats. ([International Journal of Biological Macromolecules, 2022](https://pubmed.ncbi.nlm.nih.gov/36126813/))

## How to apply

- Use this AM and PM routine every day to help clear your skin. Always remember to finish with SPF in the morning.
- Apply the moisturizer after your cleanser and toner, right before your SPF during the day.
- Gently press a small amount into your skin and avoid rubbing to keep pores clear.
- Apply on clean, slightly damp skin to help the product absorb better and control oil.
- Avoid the sensitive eye area and do a simple patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Derma-E Anti-Wrinkle Renewal Cream work for oily acne-prone skin?

This cream works moderately well for oily skin, offering smoothing and hydrating benefits, though the included oils may not be ideal for managing breakouts and excess shine. A better product for this skin needs lightweight texture, no heavy oils, and ingredients that support the skin barrier while targeting blemishes.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/)

### Which ingredients make this cream a good fit for oily acne-prone skin?

Retinol and glycerin make this cream a fit by helping hydrate and smooth texture for oily skin. To work well for this skin type, a product of this type needs lightweight hydration without heavy oils and ingredients that support the skin barrier without clogging pores.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Retinol do for oily acne-prone skin?

Retinol helps oily acne-prone skin by clearing up breakouts and smoothing the skin, though it may occasionally cause some mild scaling or stinging. This ingredient works by addressing the root causes of acne, making it a reliable choice for keeping pores clear and skin smooth.
Sources: [American Journal of Clinical Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30674002/), [Journal of Drugs in Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/30586483/)

### What does Bakuchiol do for oily acne-prone skin?

Bakuchiol helps clear oily acne-prone skin by reducing pimples and dark spots left behind. It is gentle on the face and is unlikely to cause the heavy peeling or stinging that often comes with traditional acne treatments.
Sources: [Journal of Drugs in Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33683079/), [Clinical, Cosmetic and Investigational Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25914553/)

### Where does this cream go in a skincare routine for oily acne-prone skin?

This moisturizing treatment goes in the evening routine after cleansing and before your regular moisturizer. Oily, acne-prone skin needs lightweight products with oil-free hydrators and blemish-clearing ingredients rather than heavy oils.

### Can I use this cream with vitamin C, and in what order?

You can use this cream with vitamin C, applying your vitamin C serum first in the morning or evening, followed by this moisturizer. Because this product contains retinol and oils, it is a moderate fit for oily acne-prone skin, which needs lightweight, oil-free hydration and gentle blemish-fighting ingredients to stay clear and smooth.

### How often should I use this cream?

You can use this cream in the evening as part of your routine. This product of this type needs lightweight, oil-free hydration and acne-clearing ingredients to properly care for oily, acne-prone skin.

### Can this cream clog pores, cause breakouts or purging for oily acne-prone skin?

This cream may clog pores and trigger breakouts on oily acne-prone skin because it contains oils that are not ideal for managing excess oil and blemishes. To better fit this skin type, a product needs lightweight, non-clogging hydrators and blemish-clearing ingredients that keep pores clear without heavy oils.

### Can I use this cream around the eyes or on my body?

You can use this moisturizing treatment on your body, but it is not specifically tested or formulated for the thin skin around the eyes. While the product is generally safe, body skin is thicker and tolerates heavier oils better than the delicate eye area.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for oily acne-prone skin

- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/p/cosrx/advanced-snail-96-mucin-power-essence/for/oily-acne-prone-skin) — Superior fit — $15.88 at Amazon
- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/oily-acne-prone-skin) — Superior fit — $15.50 at Amazon
- [Drunk Elephant Protini Polypeptide Cream](https://lovi.care/skincare/p/drunk-elephant/protini-polypeptide-cream/for/oily-acne-prone-skin) — High fit — $49.95 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/p/cerave/foaming-facial-cleanser/for/oily-acne-prone-skin) — Superior fit — $15.97 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — $25.60 at Amazon
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/oily-acne-prone-skin) — Superior fit — $25.99 at Amazon

## Where to buy

No store in United States has a checked price for this product, so the page shows none.

## Ingredients

Water, Carthamus Tinctorius Seed Oil, Stearic Acid, Glycerin, Glyceryl Stearate Se, Cetyl Alcohol, Microcrystalline Cellulose, Cellulose Gum, Persea Gratissima Oil Avocado Oil, Sesamum Indicum Seed Oil, Helianthus Annuus Seed Oil Sunflower Seed Oil, Bakuchiol, Retinol, Panthenol Vitamin B5, Tocopheryl Acetate Vitamin E, Allantoin, Phenoxyethanol, Ethylhexylglycerin, Oils
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/derma-e/anti-wrinkle-renewal-cream/for/oily-acne-prone-skin (this page)
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