# Dear, Klairs Midnight Blue Youth Activating Drop for sensitive skin

**Lovi Fit: Average fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/p/dear-klairs/midnight-blue-youth-activating-drop/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Dear, Klairs](https://lovi.care/skincare/brands/dear-klairs)
Category: [Serums and treatments](https://lovi.care/skincare/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for sensitive skin; other serums fit it better.

## Why this fit

- Offers moderate rejuvenation for normal skin, as Sh-Oligopeptide-1 and Sh-Polypeptide-1 stimulate collagen and boost ECM synthesis, but lacks ingredients to specifically target your redness and irritation concerns.
- Guaiazulene provides some soothing benefits, which is helpful for your sensitive skin, but the overall formulation does not prioritize anti-inflammatory action.
- The product is safe for your sensitive skin due to the absence of harsh ingredients and the inclusion of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/dear-klairs/midnight-blue-youth-activating-drop/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/p/dear-klairs/midnight-blue-youth-activating-drop/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/p/dear-klairs/midnight-blue-youth-activating-drop/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/p/dear-klairs/midnight-blue-youth-activating-drop/for/sensitive-skin): Average (this page)
- [Acne-prone skin](https://lovi.care/skincare/p/dear-klairs/midnight-blue-youth-activating-drop/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/p/dear-klairs/midnight-blue-youth-activating-drop/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/p/dear-klairs/midnight-blue-youth-activating-drop/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/p/dear-klairs/midnight-blue-youth-activating-drop/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/p/dear-klairs/midnight-blue-youth-activating-drop/for/oily-acne-prone-skin): High

## Key ingredients

Rh-Oligopeptide-1, Sh-Oligopeptide-1, Sh-Polypeptide-1, Blueberry Fruit Extract, Guaiazulene

## What the research says

- Bovine basic fibroblast growth factor combined with ultrapulsed fractional CO2 laser increased the overall response rate, reduced ECCA scores, scar base depth, skin pore value, texture value, transepidermal water loss, redness duration, scabbing duration, erythema duration, and adverse reactions, while increasing skin water and epidermal oil content in patients with acne scars compared to ultrapulsed fractional CO2 laser therapy alone. ([Clinical, Cosmetic and Investigational Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37841061/))
- Topical epidermal growth factor combined with silver sulfadiazine accelerated the rate of epidermal regeneration and significantly decreased healing time by approximately 1 to 1.5 days across all stages of healing in skin-graft-donor sites of 12 patients compared to silver sulfadiazine alone. ([The New England Journal of Medicine, 1989](https://pubmed.ncbi.nlm.nih.gov/2659995/))
- Topical recombinant human epidermal growth factor combined with ablative fractional carbon dioxide laser significantly improved striae surface texture and showed significantly greater participant satisfaction regarding marked improvement compared to ablative fractional carbon dioxide laser combined with Aloe vera gel in patients with striae alba. ([Lasers in Surgery and Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/30614013/))
- Topical EGF combined with fractional CO2 laser significantly improves the clinical appearance of atrophic acne scars and decreases skin pigmentation compared to fractional CO2 laser alone in patients with atrophic acne scars. ([The Journal of Clinical and Aesthetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35942017/))
- Topical application of PTD-EGF and FGF1 increased cell proliferation and collagen accumulation while protecting against UV-induced damage and improving wrinkle parameters in human skin. ([Journal of Cosmetic Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/24305427/))
- Basic fibroblast growth factor-loaded human serum albumin nanoparticles enhanced the proliferation and migration of human dermal fibroblasts, down-regulated myofibroblast-related genes, and accelerated wound healing with enhanced angiogenesis in vivo compared to unstable native forms. ([Journal of Nanobiotechnology, 2023](https://pubmed.ncbi.nlm.nih.gov/37658367/))
- Topical application of basic fibroblast growth factor decreases elevated transepidermal water loss and increases Ki67 expression in keratinocytes following mechanical scratching in a mouse model. ([Skin Pharmacology and Physiology, 2013](https://pubmed.ncbi.nlm.nih.gov/23108135/))
- Applying a topical product containing blueberry extract and Pro-xylane following micro-focused ultrasound significantly improved global aesthetic improvement, skin elasticity, and fine lines compared to standard moisturizer in 50 patients. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40635529/))
- Topical usage of blueberries may prevent skin damage from environmental stressors by inducing an active skin response against noxious effects. ([Antioxidants, 2023](https://pubmed.ncbi.nlm.nih.gov/37371992/))
- Pretreatment with blueberry extracts prevented ozone-induced ROS production, NLRP1-ASC scaffold formation, and CASP1 and IL-18 transcripts across 2D, 3D, and human skin explant models. ([Oxidative Medicine and Cellular Longevity, 2020](https://pubmed.ncbi.nlm.nih.gov/32855770/))

## Why other serums fit sensitive skin better

- Topical application of TAT-SOD significantly suppresses UVB-induced erythema formation, blood flow rise, and apoptotic sunburn cell formation in human volunteers compared to a vehicle control. ([European Journal of Pharmaceutics and Biopharmaceutics, 2016](https://pubmed.ncbi.nlm.nih.gov/27460952/))

## What reviewers say

Based on a very large amount of data, this product is widely praised as a lightweight, watery anti-aging serum that absorbs instantly and is exceptionally gentle, making it a favorite for oily and sensitive skin types. Many users report smoother skin texture, reduced redness, and a plump feel. Some find the 20ml bottle too small for the price and note that its preventative anti-aging effects take time to become visible.

- Liked: Rapid absorption (mostly mentioned)
- Disliked: Small volume/price (mostly mentioned)
- Liked: Gentle formula (often mentioned)
- Liked: Soothing & calming (often mentioned)
- Liked: Improves texture (sometimes noted)
- Disliked: Slow visible results (sometimes noted)
- Disliked: Watery consistency (sometimes noted)
- Disliked: Not moisturizing (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does the Midnight Blue Youth Activating Drop work for sensitive skin?

Dear, Klairs Midnight Blue Youth Activating Drop works moderately well for sensitive skin, offering some soothing benefits from guaiazulene while lacking targeted ingredients for redness and irritation. A product of this type needs powerful antioxidants, hydrating components, and specialized skin-repairing ingredients to properly calm and protect this skin.

### Which ingredients make this treatment a good fit for sensitive skin?

Guaiazulene helps soothe sensitive skin, while Sh-Oligopeptide-1 and Sh-Polypeptide-1 support skin repair without causing irritation. However, a treatment for this skin needs dedicated anti-inflammatory ingredients like niacinamide or snail secretion filtrate to properly target redness and irritation.

### What does EGF do for sensitive skin?

EGF helps calm sensitive skin by supporting barrier recovery and reducing moisture loss after irritation. It also helps protect skin cells from environmental damage and lowers inflammation to keep your face feeling soft and smooth.
Sources: [Skin Pharmacology and Physiology, 2013](https://pubmed.ncbi.nlm.nih.gov/23108135/)

### Where does this treatment go in a skincare routine for sensitive skin?

This treatment goes in the evening routine after your soothing toner and before your moisturizer. It is safe for sensitive skin because it lacks harsh ingredients and includes soothing components, though a product for this skin also needs ingredients to specifically target redness and irritation.

### Can I use this treatment with retinol, and in what order?

You can use this treatment alongside retinol by applying the treatment first and following with your retinol after it absorbs. This product is generally safe for your skin because it lacks harsh ingredients and includes soothing components.

### How often should I use this treatment?

You can use this treatment in the evening as part of your routine. This product works for your sensitive skin, though it is an average fit because it lacks ingredients to specifically target your redness and irritation. Sensitive skin needs a product of this type that also includes extra soothing components and anti-inflammatory ingredients to calm irritation.

### Can this treatment clog pores, cause breakouts or purging for sensitive skin?

This treatment is unlikely to clog pores or cause breakouts on sensitive skin due to the absence of heavy or harsh ingredients in its formula. However, because it does not trigger cell turnover like retinoids do, it will not cause purging either.

### Is this treatment fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for sensitive skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/sensitive-skin) — Superior fit — $53.00 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/p/skinceuticals/c-e-ferulic/for/sensitive-skin) — High fit — $39.99 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/p/neogen-dermalogy/real-vitamin-c-serum/for/sensitive-skin) — High fit — $25.08 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — $28.08 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/p/clarins/soothing-toning-lotion/for/sensitive-skin) — Superior fit — $28.05 at Amazon
- Moisturizer with Sun Protection: [innisfree Daily Mild Sunscreen](https://lovi.care/skincare/p/innisfree/daily-mild-sunscreen/for/sensitive-skin) — Superior fit — $18.00 at Amazon

## Where to buy

- Amazon.com: $22.00 (https://www.amazon.com/dp/B0HL91QJ2J?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Butylene Glycol, Sh-Oligopeptide-1, Sh-Polypeptide-1, Blueberry Fruit Extract, Lecithin, Sorbitan Sesquioleate, 1,2-Hexanediol, Caprylyl Glycol, Peg-60 Hydrogenated Castor Oil, Glycerin, Chlorphenesin, Guaiazulene, Ethylhexylglycerin, Adenosine
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/dear-klairs/midnight-blue-youth-activating-drop/for/sensitive-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/dear-klairs/midnight-blue-youth-activating-drop/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/dear-klairs/midnight-blue-youth-activating-drop/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/dear-klairs/midnight-blue-youth-activating-drop/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/dear-klairs/midnight-blue-youth-activating-drop/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/dear-klairs/midnight-blue-youth-activating-drop/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/dear-klairs/midnight-blue-youth-activating-drop/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/dear-klairs/midnight-blue-youth-activating-drop/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/dear-klairs/midnight-blue-youth-activating-drop/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/dear-klairs/midnight-blue-youth-activating-drop/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/dear-klairs/midnight-blue-youth-activating-drop/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/dear-klairs/midnight-blue-youth-activating-drop/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/dear-klairs/midnight-blue-youth-activating-drop/for/sensitive-skin