# COSRX The 6 Peptide Skin Booster Serum for sensitive skin

**Lovi Fit: High fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/p/cosrx/the-6-peptide-skin-booster-serum/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [COSRX](https://lovi.care/skincare/brands/cosrx)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/best/moisturizers)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for sensitive skin; a few moisturizers fit it even better.

## Why this fit

- Highly suitable for your normal skin, this serum effectively addresses redness and irritation with Niacinamide and Palmitoyl Tripeptide-8, which work to soothe inflammation and reduce redness.
- The inclusion of Acetyl Hexapeptide-8 and Copper Tripeptide-1 provides excellent moisturizing and anti-aging benefits, enhancing skin plumpness and minimizing fine lines.
- The product is safe for your sensitive skin, containing no harsh or prohibited ingredients that could cause irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/cosrx/the-6-peptide-skin-booster-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/p/cosrx/the-6-peptide-skin-booster-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/p/cosrx/the-6-peptide-skin-booster-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/p/cosrx/the-6-peptide-skin-booster-serum/for/sensitive-skin): High (this page)
- [Acne-prone skin](https://lovi.care/skincare/p/cosrx/the-6-peptide-skin-booster-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/p/cosrx/the-6-peptide-skin-booster-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/p/cosrx/the-6-peptide-skin-booster-serum/for/mature-skin): Superior
- [Dry sensitive skin](https://lovi.care/skincare/p/cosrx/the-6-peptide-skin-booster-serum/for/dry-sensitive-skin): Superior
- [Oily acne-prone skin](https://lovi.care/skincare/p/cosrx/the-6-peptide-skin-booster-serum/for/oily-acne-prone-skin): High

## Key ingredients

Sodium Hyaluronate, Peptides, N-Acetyl Glucosamine, Niacinamide, Allantoin

## What the research says

- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group. ([American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/))
- Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/))
- Argireline applied twice daily for 4 weeks achieved a total anti-wrinkle efficiency of 48.9% and notably reduced wrinkle depth compared to placebo in Chinese subjects. ([Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/))
- Topical treatment of nicotinamide, alone or in combination with other active ingredients, reduces the progression of skin aging and hyperpigmentation in clinical trials while being well tolerated. ([Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical 2% N-acetyl glucosamine reduced facial hyperpigmentation in an 8-week split-face clinical test, with an even greater effect observed when combined with 4% niacinamide. ([Journal of Cosmetic Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17348991/))
- N-acetyl-glucosamine-loaded nanostructured lipid carriers successfully delivered the hydrophilic agent through the skin and reduced melanin distribution in healthy volunteers. ([Advanced Pharmaceutical Bulletin, 2016](https://pubmed.ncbi.nlm.nih.gov/28101465/))
- Topical cosmetic products containing hyaluronic acid, N-acetyl glucosamine, and gamma-amino butyric acid improved skin hydration by 24.28% to 33.60%, elasticity by 11.98%, and skin lightening by 5.26% over 2 months in 20 female participants. ([Journal of Cosmetic and Laser Therapy, 2019](https://pubmed.ncbi.nlm.nih.gov/30040516/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical 2% niacinamide significantly decreased sebum excretion rate in Japanese individuals and casual sebum levels in Caucasian individuals compared to placebo or baseline. ([Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))

## What reviewers say

Based on a very large amount of data, users consistently praise this serum as a lightweight, water-like "booster" that significantly improves skin texture and hydration without heaviness. It is widely celebrated for smoothing pores and creating a "glass skin" glow. A small minority of users with specific sensitivities experienced breakouts or closed comedones.

- Liked: Lightweight & fast-absorbing (mostly mentioned)
- Liked: Hydrating & plumping (often mentioned)
- Liked: Improves skin texture (often mentioned)
- Liked: Gentle & non-irritating (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Ingredient sensitivities (rarely noted)
- Disliked: No visible results (rarely noted)
- Disliked: Sticky residue (rarely noted)

## How to apply

- Use this soothing AM and PM routine every day to keep your normal skin calm. Always remember to apply SPF in the morning after your moisturizer.
- Apply your moisturizer after your toner in the morning, and after your serum in the evening. This step locks in hydration and protects your skin.
- Gently press a small amount of the moisturizer evenly across your face. Avoid rubbing to keep your sensitive skin happy and calm.
- You can apply this gentle formula on dry or slightly damp skin for the best comfort. It works wonderfully on clean skin to soothe redness and irritation.
- Do a patch test before your very first use to check your skin's reaction. Avoid getting the product directly into your eyes .
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes COSRX 6 Peptide Skin Booster a great fit for sensitive skin?

This serum is a great fit because it contains Niacinamide and Palmitoyl Tripeptide-8, which help soothe redness and irritation on sensitive skin. It is also formulated safely without harsh ingredients, while peptides and Sodium Hyaluronate provide extra moisture and help smooth fine lines.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/)

### Which ingredients make this serum a good fit for sensitive skin?

This serum is a great fit for sensitive skin because it contains Niacinamide and Palmitoyl Tripeptide-8 to calm redness and irritation, along with Acetyl Hexapeptide-8 and Copper Tripeptide-1 to keep skin smooth and plump. It is also formulated safely without harsh ingredients that could trigger discomfort.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/)

### What does Hyaluronic Acid do for sensitive skin?

Hyaluronic acid helps calm and hydrate sensitive skin while supporting the skin barrier to keep it soft and comfortable. Clinical studies show it improves surface moisture and reduces dryness, roughness, and redness without irritation.
Sources: [Journal of Drugs in Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41037531/), [Journal of Cosmetic Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29356277/)

### What do Peptides do for sensitive skin?

Peptides help support the skin barrier and improve the feel of sensitive skin by encouraging firmness and a smooth look. When paired with soothing and hydrating ingredients, peptide products are generally well tolerated and unlikely to cause irritation.
Sources: [Advanced Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39783908/), [Journal of Biomedical Materials Research, 1998](https://pubmed.ncbi.nlm.nih.gov/9457557/)

### Where does this serum go in a skincare routine for sensitive skin?

This serum goes in the evening routine after your soothing toner and before your moisturizer. It is safe for sensitive skin because it contains no harsh ingredients that could cause irritation.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying it right before your retinol to help keep your sensitive skin calm and hydrated. This type of routine helps soothe irritation while supporting your skin barrier during active treatments.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22648223/)

### How often should I use this serum?

You can safely use this serum in your evening routine every day. Daily application helps keep your sensitive skin calm and well moisturized.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this serum clog pores, cause breakouts or purging for sensitive skin?

This serum is unlikely to clog pores or cause breakouts for sensitive skin, as it has a very safe profile with negligible risk of ingredient sensitivities and low reviewer complaints about breakouts. It helps soothe redness and calm irritation while providing gentle moisture.

### Can I use this serum around the eyes or on my body?

This serum is a great fit for sensitive skin, making it safe to use around the eyes and on the body. Its gentle ingredients like Sodium Hyaluronate and Allantoin help hydrate and soothe delicate areas without causing irritation.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37896378/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for sensitive skin

- [innisfree Green Tea Seed Hyaluronic Acid Hydrating Serum](https://lovi.care/skincare/p/innisfree/green-tea-seed-hyaluronic-acid-hydrating-serum/for/sensitive-skin) — High fit — $30.00 at Amazon
- [Isntree Green Tea Fresh Serum](https://lovi.care/skincare/p/isntree/green-tea-fresh-serum/for/sensitive-skin) — High fit — $17.90 at Amazon
- [Revision Skincare Hydrating Serum](https://lovi.care/skincare/p/revision-skincare/hydrating-serum/for/sensitive-skin) — High fit — $109.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — $28.08 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/p/clarins/soothing-toning-lotion/for/sensitive-skin) — Superior fit — $28.05 at Amazon
- Moisturizer with Sun Protection: [innisfree Daily Mild Sunscreen](https://lovi.care/skincare/p/innisfree/daily-mild-sunscreen/for/sensitive-skin) — Superior fit — $18.00 at Amazon

## Where to buy

- Amazon.com: $17.50 (https://www.amazon.com/dp/B0CCJ3SRB9?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Dipropylene Glycol, Glycerin, Pentylene Glycol, 1,2-Hexanediol, Niacinamide, Ammonium Acryloyldimethyltaurate Vp Copolymer, Polyacrylate Crosspolymer-6, Butylene Glycol, Xanthan Gum, Ethylhexylglycerin, Adenosine, Polyquaternium-51, Disodium Edta, Citric Acid, Caprylyl Glycol, Betaine, T-Butyl Alcohol, Sodium Pca, Sodium Lactate, Acetyl Hexapeptide-8, Copper Tripeptide-1, Pca, Sh-Polypeptide-121, Serine, Alanine, Allantoin, Sodium Hyaluronate, Acetyl Glucosamine, Glycine, Glutamic Acid, Lysine Hcl, Threonine, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Arginine, Tocopherol, Oligopeptide-68, Proline, Dextran, Palmitoyl Tripeptide-8, Glycine Soja Oil Soybean Oil, Hydrogenated Lecithin, Potassium Sorbate, Sodium Oleate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/cosrx/the-6-peptide-skin-booster-serum/for/sensitive-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/cosrx/the-6-peptide-skin-booster-serum/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/cosrx/the-6-peptide-skin-booster-serum/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/cosrx/the-6-peptide-skin-booster-serum/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/cosrx/the-6-peptide-skin-booster-serum/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/cosrx/the-6-peptide-skin-booster-serum/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/cosrx/the-6-peptide-skin-booster-serum/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/cosrx/the-6-peptide-skin-booster-serum/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/cosrx/the-6-peptide-skin-booster-serum/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/cosrx/the-6-peptide-skin-booster-serum/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/cosrx/the-6-peptide-skin-booster-serum/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/cosrx/the-6-peptide-skin-booster-serum/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/cosrx/the-6-peptide-skin-booster-serum/for/sensitive-skin