# CLIV PHA Mild Enzyme Powder for combination skin

**Lovi Fit: High fit for combination skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/p/cliv/pha-mild-enzyme-powder/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: CLIV
Category: [Exfoliants](https://lovi.care/skincare/best/exfoliators)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for combination skin; a few products fit it even better.

## Why this fit

- Offers high suitability for your combination skin, as papain and bromelain provide enzymatic exfoliation to address oily shine, while sodium hyaluronate ensures adequate hydration.
- The inclusion of allantoin and Lactobacillus Punica Granatum Extract Fruit Ferment further soothes and supports your skin's barrier function.
- The product is safe for your skin, with no risk of irritation due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/cliv/pha-mild-enzyme-powder/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/p/cliv/pha-mild-enzyme-powder/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/p/cliv/pha-mild-enzyme-powder/for/combination-skin): High (this page)
- [Sensitive skin](https://lovi.care/skincare/p/cliv/pha-mild-enzyme-powder/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/p/cliv/pha-mild-enzyme-powder/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/p/cliv/pha-mild-enzyme-powder/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/p/cliv/pha-mild-enzyme-powder/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/p/cliv/pha-mild-enzyme-powder/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/p/cliv/pha-mild-enzyme-powder/for/oily-acne-prone-skin): High

## Key ingredients

Papain, Bromelain, Gluconolactone, Sodium Hyaluronate, Allantoin

## What the research says

- A fixed combination of hydroxypinacolone retinoate, retinol glycospheres, and papain glycospheres in aqueous gel applied once daily for 12 weeks achieved a 41% mean reduction in GAGS score and a 40.8% mean reduction in total lesions, with 15.3% of patients experiencing mild to moderate local side effects, in 94 evaluable patients with comedonal-papular, mild to moderate acne of the face. ([Giornale Italiano Di Dermatologia E Venereologia, 2015](https://pubmed.ncbi.nlm.nih.gov/25876142/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- Hyaluronic acid extracts are safe and efficacious products for skin repair when used in tissue regeneration alone or in combination with herbal or Western medicine. ([Journal of Pharmacy & Pharmaceutical Sciences, 2015](https://pubmed.ncbi.nlm.nih.gov/25877441/))
- Combining 10% gluconolactone chemical peeling with oxybrasion or microneedle mesotherapy increased skin hydration and decreased sebum, pH, and TEWL in twenty-one Caucasian women, with no significant differences between the two methods. ([Skin Research and Technology, 2023](https://pubmed.ncbi.nlm.nih.gov/37357656/))
- Topical papain treatment may slightly decrease pain within 30 minutes in humans stung by Chrysaora chinensis compared to placebo. ([Wilderness & Environmental Medicine, 2016](https://pubmed.ncbi.nlm.nih.gov/26827260/))
- Reflux extraction of Carica papaya leaves yielded higher antioxidant capacity and superior in vitro wound-healing activities including fibroblast proliferation, cell migration, and collagen synthesis in human skin fibroblasts compared to ultrasonic-assisted extraction and agitation. ([Molecules, 2020](https://pubmed.ncbi.nlm.nih.gov/31991676/))
- Carica papaya leaf extracts obtained via supercritical fluid and conventional methods demonstrated antioxidant and cytoprotective effects on skin fibroblasts against oxidative stress, driven by their respective lipophilic and hydrophilic constituents. ([Molecules, 2021](https://pubmed.ncbi.nlm.nih.gov/33803330/))
- Oral bromelain slightly reduced pain compared to controls (mean difference -0.27) and topical bromelain reduced time to complete debridement by 6.89 days, with no major health risks reported. ([Nutrition and Health, 2023](https://pubmed.ncbi.nlm.nih.gov/37157782/))
- An upcycled pineapple leaf fibre crosspolymer forms a physical barrier that protects against environmental aggressors while providing antioxidant, anti-inflammatory, antipollution, UV protection, hydration, and hair benefits. ([International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/41524117/))
- A coaxial electrospun core-shell nanofiber scaffold delivering bromelain and salvianolic acid B demonstrated sustained drug release, in vitro endothelial cell migration, increased capillary formation in an in ovo assay, and in vivo efficacy for skin regeneration and wound healing. ([Biomedical Materials, 2017](https://pubmed.ncbi.nlm.nih.gov/28580904/))
- Glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene showed no hindrance compared to adapalene monotherapy and provided benefits in reducing complications in 25 subjects with mild-to-moderate acne vulgaris. ([Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30858720/))
- Gluconolactone and tartaric acid significantly lower transepidermal water loss and erythema after sodium lauryl sulphate challenge compared to vehicle, untreated control, and glycolic acid in healthy subjects. ([The British Journal of Dermatology, 1997](https://pubmed.ncbi.nlm.nih.gov/9470910/))
- Gluconolactone 14% solution significantly improved mild to moderate acne by reducing inflamed and non-inflamed lesions similarly to 5% benzoyl peroxide, but with fewer side-effects in 150 patients. ([The Australasian Journal of Dermatology, 1992](https://pubmed.ncbi.nlm.nih.gov/1303072/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))
- Prophylactic application of a topical scar gel containing Allium cepae extract, allantoin, and heparin significantly improves patient-assessed scar color, stiffness, and irregularity compared to no treatment in women following a cesarean section. ([Journal of Drugs in Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/24509969/))
- Prophylactic use of a topical gel containing Allium cepa extract, allantoin and heparin significantly reduced vascularity, pigmentation and height of scars compared to an untreated control group and in intra-individual analysis in 120 patients after caesarean section. ([Journal of Wound Care, 2020](https://pubmed.ncbi.nlm.nih.gov/33052789/))

## What reviewers say

Based on limited data, this enzyme powder is highly praised for its ability to gently exfoliate and deeply cleanse the skin without causing irritation or dryness. Users with sensitive and mixed skin types report that it effectively removes impurities and makeup, leaving the skin feeling exceptionally smooth, soft, and hydrated.

- Liked: Non-stripping cleanse (mostly mentioned)
- Liked: Gentle exfoliation (often mentioned)
- Liked: Skin texture improvement (often mentioned)
- Disliked: Limited availability (often mentioned)
- Liked: Suitable for sensitive skin (sometimes noted)
- Disliked: Price point (sometimes noted)
- Disliked: Messy application (rarely noted)
- Disliked: Potential irritants (rarely noted)

## How to apply

- Use this enzyme powder exfoliant in your PM weekly routine. Start 1x/week and increase frequency slowly if your skin tolerates it well.
- Apply this enzyme powder exfoliant after your cleaner and before your hydrating toner. Follow up with your regular serum and moisturizer.
- Dispense a small amount of the enzyme powder exfoliant into wet hands and lather into a soft foam. Gently massage onto your face while avoiding any harsh rubbing.
- Apply this enzyme powder exfoliant to slightly damp skin to help with even distribution. Rinse thoroughly with lukewarm water after a minute.
- Avoid the eye area and do a patch test before your first use. Stop using this enzyme powder exfoliant if you notice any irritation.
- Video: https://storage.pora.ai/767f9b79c33b777aa28f84f66e309d62.mp4

## Questions and answers

### What makes CLIV PHA Mild Enzyme Powder a great fit for combination skin?

CLIV PHA Mild Enzyme Powder is a great fit because papain and bromelain provide gentle enzymatic exfoliation to help control oily shine while sodium hyaluronate keeps your skin hydrated. Allantoin and fruit ferment extracts further soothe the skin and support your barrier without causing irritation.
Sources: [Giornale Italiano Di Dermatologia E Venereologia, 2015](https://pubmed.ncbi.nlm.nih.gov/25876142/), [Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/)

### Which ingredients make this exfoliant a good fit for combination skin?

Papain and bromelain make this exfoliant a great fit for combination skin by providing gentle enzymatic exfoliation to manage oily shine, while sodium hyaluronate keeps skin hydrated. Additionally, allantoin helps soothe the skin and support its barrier function.
Sources: [Giornale Italiano Di Dermatologia E Venereologia, 2015](https://pubmed.ncbi.nlm.nih.gov/25876142/), [Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/)

### What does Papain do for combination skin?

Papain gently exfoliates the skin by breaking down dead surface proteins, which helps keep oily and dry areas balanced and smooth. It is unlikely to cause severe irritation when used properly, though mild tingling may occur.
Sources: [International Journal of Cosmetic Science, 2022](https://pubmed.ncbi.nlm.nih.gov/35892222/)

### What does Bromelain do for combination skin?

Bromelain helps clear away dead skin and smooth out rough areas by gently breaking down outer skin proteins. A product of this type needs soothing hydrators and gentle exfoliants to balance combination skin without causing irritation.
Sources: [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34897928/)

### Where does this exfoliant go in a skincare routine for combination skin?

This exfoliant is used once a week as part of your weekly routine, applied after cleansing and before your mask and toner. It helps address oily shine while keeping your skin calm and hydrated.

### Can I use this exfoliant with retinol, and in what order?

You can use this enzyme powder exfoliant in your weekly routine, but avoid applying it on the same nights you use your retinol treatment to prevent irritation. Use the powder after your cleanser on your weekly exfoliation night, and save your retinol for a different evening.
Sources: [Giornale Italiano Di Dermatologia E Venereologia, 2015](https://pubmed.ncbi.nlm.nih.gov/25876142/), [Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/)

### How often should I use this exfoliant?

This exfoliant is a great fit for your combination skin, and you can start using it once a week. People who tolerate it well and see good results may carefully use it more often.

### Can this exfoliant clog pores, cause breakouts or purging for combination skin?

This exfoliant is unlikely to clog pores or cause breakouts for your combination skin, as it contains soothing and gentle components with no harsh ingredients that could irritate. It helps smooth the skin while keeping areas calm and hydrated.
Sources: [Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/), [Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/)

### Is this exfoliant fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [Dermalogica Daily Microfoliant](https://lovi.care/skincare/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — $69.00 at Amazon
- [Dermalogica Daily Superfoliant](https://lovi.care/skincare/p/dermalogica/daily-superfoliant/for/combination-skin) — High fit — $19.50 at Amazon
- [Good Molecules Pineapple Exfoliating Powder](https://lovi.care/skincare/p/good-molecules/pineapple-exfoliating-powder/for/combination-skin) — High fit — $16.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — $28.08 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — $25.60 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — $18.99 at Amazon

## Where to buy

No store in United States has a checked price for this product, so the page shows none.

## Ingredients

Zea Mays Starch, Sodium Cocoyl Isethionate, Sodium Lauroyl Glutamate, Sodium Palmitate, Diglycerin, Allantoin, Maltodextrin, Papain, Bromelain, Gluconolactone, Sodium Hyaluronate, Lauryl Betaine, Sodium Chloride, Lactobacillus Punica Granatum Extract Fruit Ferment, Portulaca Oleracea Extract, Rosa Multiflora Fruit Extract, Ceratonia Siliqua Fruit Extract, Chenopodium Quinoa Seed Extract, Lens Esculenta Fruit Extract, Nelumbo Nucifera Seed Extract, Glycerin, 1,2-Hexanediol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/cliv/pha-mild-enzyme-powder/for/combination-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/cliv/pha-mild-enzyme-powder/for/combination-skin
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- Canada: https://lovi.care/skincare/ca/p/cliv/pha-mild-enzyme-powder/for/combination-skin
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