# Clean & Clear Persa-Gel 10 for combination skin

**Lovi Fit: High fit for combination skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/p/clean-and-clear/persa-gel-10/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Clean & Clear](https://lovi.care/skincare/brands/clean-and-clear)
Category: [Serums and treatments](https://lovi.care/skincare/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for combination skin; a few serums fit it even better.

## Why this fit

- Offers high suitability for your combination skin and oily shine concerns, as benzoyl peroxide effectively targets acne-causing bacteria and reduces excess oil without causing irritation.
- Benzyl alcohol provides a soothing effect, further enhancing comfort for your skin type.
- The formulation is safe for your skin, containing no harsh ingredients and including soothing agents.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/clean-and-clear/persa-gel-10/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/p/clean-and-clear/persa-gel-10/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/p/clean-and-clear/persa-gel-10/for/combination-skin): High (this page)
- [Sensitive skin](https://lovi.care/skincare/p/clean-and-clear/persa-gel-10/for/sensitive-skin): Low
- [Acne-prone skin](https://lovi.care/skincare/p/clean-and-clear/persa-gel-10/for/acne-prone-skin): Superior
- [Skin with dark spots](https://lovi.care/skincare/p/clean-and-clear/persa-gel-10/for/dark-spots): Low
- [Mature skin](https://lovi.care/skincare/p/clean-and-clear/persa-gel-10/for/mature-skin): Low
- [Dry sensitive skin](https://lovi.care/skincare/p/clean-and-clear/persa-gel-10/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/p/clean-and-clear/persa-gel-10/for/oily-acne-prone-skin): Superior

## Key ingredients

Benzoyl Peroxide, Carbomer Homopolymer Type B, Hydroxypropyl Methylcellulose, Sodium Hydroxide

## What the research says

- Preoperative treatment with benzoyl peroxide significantly decreases the bacterial skin load of Cutibacterium acnes in patients undergoing elective shoulder surgery from skin incision until wound closure compared to preparation with soap. ([Journal of Shoulder and Elbow Surgery, 2021](https://pubmed.ncbi.nlm.nih.gov/33545336/))
- Topical benzoyl peroxide may improve acne more effectively than placebo or no treatment, while showing little to no difference compared with adapalene or clindamycin, but with an increased risk of treatment discontinuation due to adverse effects compared to placebo. ([The Cochrane Database of Systematic Reviews, 2020](https://pubmed.ncbi.nlm.nih.gov/32175593/))
- Once-daily fixed-dose clindamycin phosphate 1.2%/benzoyl peroxide 3.1%/adapalene 0.15% gel achieved superior treatment success (52.5%) and greater reductions in inflammatory and noninflammatory lesions compared to vehicle (8.1%) and dyad component gels in participants with moderate-to-severe acne over 12 weeks. ([American Journal of Clinical Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34674160/))
- Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate can be used safely in cosmetic formulations at concentrations up to 5%, and Benzyl Alcohol is safe up to 10% in hair dyes, despite causing nonimmunologic contact reactions. ([International Journal of Toxicology, 2001](https://pubmed.ncbi.nlm.nih.gov/11766131/))
- Twice daily application of a multitargeted dermocosmetic cream provided comparable efficacy to benzoyl peroxide 5% gel in reducing inflammatory, non-inflammatory, and total lesions in 150 Caucasian subjects with mild-to-moderate acne over 56 days, while demonstrating superior skin tolerability. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/))
- Topical clindamycin phosphate 1.2%/adapalene 0.15%/benzoyl peroxide 3.1% gel achieved significantly greater treatment success and lesion reductions compared to vehicle in participants with moderate-to-severe acne. ([Journal of the American Academy of Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37656094/))
- Daily application of adapalene 0.3%/benzoyl peroxide 2.5% gel reduced and prevented atrophic acne scar formation, achieving a total scar count change of -15.5% versus +14.4% for vehicle over 24 weeks in 67 subjects with moderate or severe facial acne. ([American Journal of Clinical Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29549588/))
- Topical chloramphenicol-betamethasone combined with sodium hyaluronate/trehalose/carbomer gel compared to chloramphenicol-betamethasone alone reduced most subjective symptoms at 1 week but increased blurred vision at 4 weeks following strabismus surgery in 31 patients, with no significant differences in conjunctival inflammation between treatments. ([Journal of Ocular Pharmacology and Therapeutics, 2019](https://pubmed.ncbi.nlm.nih.gov/31298607/))
- Incorporating nanoemulsions into hydrogels with increasing Carbopol 934 proportions from 1% to 3% progressively decreased the percutaneous flux rates of terbinafine and citral, increased drug accumulation in the stratum corneum while decreasing it in the epidermis/dermis compared to nanoemulsions alone, and shifted delivery routes from skin appendages to intercellular paths. ([International Journal of Nanomedicine, 2016](https://pubmed.ncbi.nlm.nih.gov/27877042/))
- Topical liquiritin carbomer gel treatment restored skin barrier function, increased barrier proteins and antioxidant enzymes, and decreased inflammatory cytokines and oxidative stress in a mouse model of glucocorticoid-induced skin inflammation. ([Pharmaceutics, 2024](https://pubmed.ncbi.nlm.nih.gov/39204346/))
- Biodegradable wound dressings functionalized with silver nanoparticles showed >99% pathogen growth inhibition, bactericidal effects, free radical scavenging, reduced inflammatory response in macrophages, and accelerated wound healing in animals. ([International Journal of Biological Macromolecules, 2022](https://pubmed.ncbi.nlm.nih.gov/35780920/))
- Hydroxypropyl methylcellulose hydrogel formulations of berberine chloride-loaded escinosomes increased skin residence time and transdermal permeability while maintaining high safety and biocompatibility without skin irritation. ([International Journal of Biological Macromolecules, 2020](https://pubmed.ncbi.nlm.nih.gov/32682035/))

## What reviewers say

Based on a very large amount of data, users consistently praise this maximum-strength benzoyl peroxide gel as a highly effective and affordable spot treatment for stubborn acne and cystic bumps. Because of its potency, it frequently causes significant dryness and peeling, making it best suited for oily skin types or targeted application rather than all-over use.

- Liked: Affordable price (mostly mentioned)
- Disliked: Excessive drying (mostly mentioned)
- Liked: Clears pimples (often mentioned)
- Liked: Effective spot treatment (often mentioned)
- Disliked: Bleaches fabrics (often mentioned)
- Disliked: Causes burning (sometimes noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Clean & Clear Persa-Gel 10 a great fit for combination skin?

Clean & Clear Persa-Gel 10 is a great fit because benzoyl peroxide targets acne-causing bacteria and reduces excess oil, while benzyl alcohol soothes your skin. This combination offers excellent suitability for combination skin and oily shine without harsh ingredients.
Sources: [Journal of Shoulder and Elbow Surgery, 2021](https://pubmed.ncbi.nlm.nih.gov/33545336/), [The Cochrane Database of Systematic Reviews, 2020](https://pubmed.ncbi.nlm.nih.gov/32175593/)

### Which ingredients make this treatment a good fit for combination skin?

Benzoyl peroxide and benzyl alcohol make this treatment a great fit for your combination skin. Benzoyl peroxide helps target acne-causing bacteria and reduces excess oil, while benzyl alcohol provides a soothing effect to keep your skin comfortable.
Sources: [Journal of Shoulder and Elbow Surgery, 2021](https://pubmed.ncbi.nlm.nih.gov/33545336/), [International Journal of Toxicology, 2001](https://pubmed.ncbi.nlm.nih.gov/11766131/)

### What does Benzoyl Peroxide do for combination skin?

Benzoyl peroxide helps clear acne and reduce blemishes for combination skin by targeting breakout-causing bacteria. Because it can sometimes cause dryness or tightness in sensitive areas, it is important to follow with a good moisturizer to keep the skin balanced.
Sources: [The Cochrane Database of Systematic Reviews, 2020](https://pubmed.ncbi.nlm.nih.gov/32175593/), [Journal of Drugs in Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23839205/)

### What does Water do for combination skin?

Water helps keep combination skin hydrated, though a product of this type needs additional barrier-protecting ingredients like ceramides or petrolatum to lock in that moisture and support overall skin health.

### Where does this treatment go in a skincare routine for combination skin?

Clean & Clear Persa-Gel 10 goes in your evening routine as a treatment step, used after cleansing and toning and before your moisturizer. This keeps things simple and provides extra safety around sun exposure when using active ingredients like benzoyl peroxide.

### Can I use this treatment with retinol, and in what order?

You can use this treatment with retinol by applying them on alternating nights or separating them into different routines to keep your skin calm. Using both together in the same routine may be too strong and cause dryness, so alternating helps your skin stay smooth and comfortable.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/), [American Family Physician, 2012](https://pubmed.ncbi.nlm.nih.gov/23062156/)

### How often should I use this treatment?

Use this treatment in your evening routine. It contains benzoyl peroxide, which helps target acne-causing bacteria and reduce excess oil.
Sources: [Journal of Shoulder and Elbow Surgery, 2021](https://pubmed.ncbi.nlm.nih.gov/33545336/), [The Cochrane Database of Systematic Reviews, 2020](https://pubmed.ncbi.nlm.nih.gov/32175593/)

### Can this treatment clog pores, cause breakouts or purging for combination skin?

This treatment is a great fit for your combination skin because benzoyl peroxide targets acne-causing bacteria and reduces oily shine without causing irritation. While it is unlikely to clog pores, it may cause excessive drying or burning in some people.
Sources: [Journal of Shoulder and Elbow Surgery, 2021](https://pubmed.ncbi.nlm.nih.gov/33545336/), [The Cochrane Database of Systematic Reviews, 2020](https://pubmed.ncbi.nlm.nih.gov/32175593/)

### Is this treatment fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (benzyl alcohol).

## Alternatives for combination skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/combination-skin) — Superior fit — $16.75 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin) — Superior fit — $28.88 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/p/augustinus-bader/the-serum/for/combination-skin) — Superior fit — $200.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — $28.08 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — $25.60 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — $18.99 at Amazon

## Where to buy

- Amazon.com: $5.43 (https://www.amazon.com/dp/B00KZ22ED4?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Benzoyl Peroxide, Water, Carbomer Homopolymer Type B, Hydroxypropyl Methylcellulose, Sodium Hydroxide, Laureth-4, Disodium Edta, Benzyl Alcohol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/clean-and-clear/persa-gel-10/for/combination-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/clean-and-clear/persa-gel-10/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/clean-and-clear/persa-gel-10/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/clean-and-clear/persa-gel-10/for/combination-skin
- France: https://lovi.care/skincare/fr/p/clean-and-clear/persa-gel-10/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/clean-and-clear/persa-gel-10/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/clean-and-clear/persa-gel-10/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/clean-and-clear/persa-gel-10/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/clean-and-clear/persa-gel-10/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/clean-and-clear/persa-gel-10/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/clean-and-clear/persa-gel-10/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/clean-and-clear/persa-gel-10/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/clean-and-clear/persa-gel-10/for/combination-skin