# Cica-Hyalon Reedle Shot 100 for mature skin

**Lovi Fit: Superior fit for mature skin.**
Normal Skin Fit: Superior · Effectiveness: Superior · Safety: Excellent.

Page: https://lovi.care/skincare/p/cica-hyalon/reedle-shot-100/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Cica-Hyalon](https://lovi.care/skincare/brands/cica-hyalon)
Category: [Exfoliants](https://lovi.care/skincare/best/exfoliators)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best products for mature skin.

## Why this fit

- Excellent suitability for your normal skin is provided by Glycerin and Hyaluronic Acid for humectant action and Centella Asiatica Extract for anti-inflammatory benefits, which work synergistically to hydrate and soothe.
- The formula offers excellent exfoliation and skin treatment due to the presence of asiaticoside, madecassoside, and madecassic acid, promoting skin renewal and healing for your wrinkles and fine lines.
- The safety profile is excellent, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/cica-hyalon/reedle-shot-100/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/p/cica-hyalon/reedle-shot-100/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/p/cica-hyalon/reedle-shot-100/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/p/cica-hyalon/reedle-shot-100/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/p/cica-hyalon/reedle-shot-100/for/acne-prone-skin): Superior
- [Skin with dark spots](https://lovi.care/skincare/p/cica-hyalon/reedle-shot-100/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/p/cica-hyalon/reedle-shot-100/for/mature-skin): Superior (this page)
- [Dry sensitive skin](https://lovi.care/skincare/p/cica-hyalon/reedle-shot-100/for/dry-sensitive-skin): Superior
- [Oily acne-prone skin](https://lovi.care/skincare/p/cica-hyalon/reedle-shot-100/for/oily-acne-prone-skin): High

## Key ingredients

Centella Asiatica, Hyaluronic Acid, Niacinamide, Centella Asiatica Extract, Propolis Extract

## What the research says

- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Topical treatment of nicotinamide, alone or in combination with other active ingredients, reduces the progression of skin aging and hyperpigmentation in clinical trials while being well tolerated. ([Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Treatment with an asiaticoside-containing cream applied twice daily for 12 weeks significantly improved periorbital wrinkles in 65% of 27 female volunteers compared to a vehicle control cream. ([International Journal of Cosmetic Science, 2008](https://pubmed.ncbi.nlm.nih.gov/18452433/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Topical propolis application significantly reduced postoperative pain, hemorrhage, and accelerated wound healing in patients undergoing tonsillectomy compared to a control group. ([Clinical and Experimental Otorhinolaryngology, 2018](https://pubmed.ncbi.nlm.nih.gov/29665628/))
- Topical treatment with ethanol propolis extract resulted in complete mycological and clinical cure in 56.25% of patients with onychomycosis, demonstrating non-toxicity and effective antifungal activity against Trichophyton spp. both in vitro and in patients. ([Frontiers in Microbiology, 2018](https://pubmed.ncbi.nlm.nih.gov/29922236/))

## What reviewers say

Based on a very large amount of data, users describe this product as a potent treatment that significantly refines skin texture and enhances the absorption of other skincare products. The characteristic tingling sensation is widely noted. Most users with concerns like dullness, enlarged pores, or rough texture report achieving smoother, more radiant skin and a reduction in acne scarring with regular application, which should be taken into account.

- Liked: Smoother Skin Texture (mostly mentioned)
- Disliked: Prickling/Tingling Sensation (mostly mentioned)
- Liked: Enhances Product Absorption (often mentioned)
- Liked: Brightens & Glows (sometimes noted)
- Liked: Reduces Pores & Acne (sometimes noted)
- Disliked: Insufficient Hydration (rarely noted)
- Disliked: Lack of Visible Results (rarely noted)
- Disliked: Purging or Breakouts (rarely noted)

## How to apply

- Use this exfoliant product in your PM routine once a week to start, increasing frequency only if your skin tolerates it well. Always apply SPF the next morning to protect your skin.
- Apply this exfoliant product after cleansing and toner, but before your moisturizer. This ensures the best absorption into your skin.
- Gently press 2-3 drops of the exfoliant product into your face, avoiding any rubbing. Let it absorb for a minute before moving to the next step.
- Apply this exfoliant product on completely dry skin to get the best results. This helps your normal skin accept the product smoothly.
- Avoid the sensitive eye area while using this exfoliant product. Do a patch test before your first use and avoid mixing it with strong acids.
- Video: https://storage.pora.ai/028e5e793422a3b665c02ff502cf5a68.mp4

## Questions and answers

### What makes Cica-Hyalon Reedle Shot 100 one of the best fits for mature skin?

Cica-Hyalon Reedle Shot 100 is one of the best fits for mature skin because glycerin and hyaluronic acid keep skin hydrated while centella asiatica extract soothes it. Its specific ingredients also promote skin renewal and healing to help smooth out wrinkles and fine lines with an extremely low risk of irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Which ingredients make this exfoliant a good fit for mature skin?

This exfoliant is a great fit for mature skin because ingredients like hyaluronic acid and glycerin hydrate dry areas, while centella asiatica extract and asiaticoside help calm skin and smooth out fine lines. It is also very safe to use with a low risk of irritation.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Centella Asiatica do for mature skin?

Centella asiatica helps mature skin by boosting moisture, keeping it smooth, and supporting collagen to make skin look firmer and less wrinkled. It also helps calm redness and protect skin from daily stress and aging.
Sources: [International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/41516082/), [Scientific Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34188145/)

### What does Hyaluronic Acid do for mature skin?

Hyaluronic acid helps mature skin by deeply boosting moisture, improving elasticity, and smoothing the appearance of fine lines and wrinkles. Regular use keeps the skin looking plump and soft while supporting overall firmness and hydration.
Sources: [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/), [Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38591218/)

### Where does this exfoliant go in a skincare routine for mature skin?

This exfoliant treatment is applied in the evening. Lovi routines put treatments with active ingredients in the PM to keep things simple and safe around sun exposure, and they are usually started once a week.

### Can I use it with retinol, and in what order?

This product is generally unlikely to cause irritation when combined thoughtfully, but using it with retinol requires caution since both encourage skin renewal. Apply your retinol on alternate nights or keep them in separate routines to help your skin stay calm and smooth.

### How often should I use it?

This exfoliant treatment is a great fit for mature skin and should be used once a week in your evening routine. If your skin tolerates it well and you see good results, you may carefully use it more often.

### Can this exfoliant clog pores, cause breakouts or purging for mature skin?

This exfoliant is unlikely to cause breakouts or purging for mature skin, as it has a very low likelihood of these issues and features soothing ingredients that help keep skin calm. The formula relies on gentle components with a very safe profile, so it should not clog your pores.

### Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for mature skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/mature-skin) — Superior fit — $53.00 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/p/skinceuticals/c-e-ferulic/for/mature-skin) — Superior fit — $39.99 at Amazon
- [Drunk Elephant A-Passioni Retinol Cream](https://lovi.care/skincare/p/drunk-elephant/a-passioni-retinol-cream/for/mature-skin) — High fit — $76.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — $28.08 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — $17.00 at Amazon
- Moisturizer: [Obagi Hydrate Luxe Moisture-Rich Cream](https://lovi.care/skincare/p/obagi/hydrate-luxe/for/mature-skin) — Superior fit — $85.00 at Amazon

## Where to buy

- Amazon.com: $23.40 (https://www.amazon.com/dp/B0C2TQ24VY?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Dipropylene Glycol, Glycerin, Niacinamide, Butylene Glycol, Macadamia Ternifolia Seed Oil, 1,2-Hexanediol, Ethylhexyl Palmitate, Sodium Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Polyisobutene, Silica, Glycereth-26, Ethylhexylglycerin, Caprylyl Glycol, Adenosine, Sodium Polyacrylate, Hyaluronic Acid, Centella Asiatica Extract, Caprylyl Capryl Glucoside, Sorbitan Oleate, Xanthan Gum, Propolis Extract, Asiaticoside, Madecassoside, Madecassic Acid, Asiatic Acid, Glycine, Serine, Glutamic Acid, Aspartic Acid, Leucine, Alanine, Lysine, Arginine, Tyrosine, Phenylalanine, Threonine, Proline, Valine, Isoleucine, Histidine, Methionine, Cysteine
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/cica-hyalon/reedle-shot-100/for/mature-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/cica-hyalon/reedle-shot-100/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/cica-hyalon/reedle-shot-100/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/cica-hyalon/reedle-shot-100/for/mature-skin
- France: https://lovi.care/skincare/fr/p/cica-hyalon/reedle-shot-100/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/cica-hyalon/reedle-shot-100/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/cica-hyalon/reedle-shot-100/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/cica-hyalon/reedle-shot-100/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/cica-hyalon/reedle-shot-100/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/cica-hyalon/reedle-shot-100/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/cica-hyalon/reedle-shot-100/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/cica-hyalon/reedle-shot-100/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/cica-hyalon/reedle-shot-100/for/mature-skin