CHANEL Le Lift Crème Yeux for mature skin

Questions and answers

What the research says

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone.

  Dermatologic Therapy, 2022

• Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants.

  Journal of Cosmetic Dermatology, 2026

• A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo.

  Journal of Cosmetic Dermatology, 2015

• A body cream formulation containing coffee silverskin and Medicago sativa extracts demonstrated stability over 180 days, no in vitro cell toxicity, skin safety without irritant effects, and improved skin hydration after 30 days of use in human subjects.

  Drug Development and Industrial Pharmacy, 2016

• Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components.

  International Journal of Cosmetic Science, 2026

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events.

  Lasers in Medical Science, 2025

• A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells.

  International Journal of Cosmetic Science, 2025

• Alfalfa and polycaprolactone composite nanofibers enhanced cellular proliferation of dermal fibroblasts and epidermal keratinocytes in vitro and promoted re-epithelialization and granulation tissue formation in mouse and human skin.

  ACS Applied Materials & Interfaces, 2019

• Medicago sativa methanol extract combined with UVA light enhanced skin and hair pigmentation in a hydroquinone-induced depigmentation mouse model compared to reference, placebo, and control groups.

  Journal of Cosmetic Dermatology, 2022

• A hydroxypropyl-beta-cyclodextrin-based extract of Medicago sativa reduced glycosaminoglycan levels by 41.2% and 51.1% at concentrations of 3 and 6 microg/mL in skin fibroblasts of a mucopolysaccharidose III patient.

  Planta Medica, 2017

Ingredients

Water, Glycerin, Butylene Glycol, Aluminum Octenylsuccinate Starch, Cetearyl Alcohol, Isododecane, Isostearyl Neopentanoate, Butyrospermum Parkii Butter Shea Butter, Pentylene Glycol, Peg-8, Rice Powder, Squalane, Ipomoea Batatas Root Extract, Medicago Sativa Extract, Yeast Extract, Alba Cera Beeswax Cera, Jojoba Esters, Dipropylene Glycol, Glyceryl Stearate, Peg-100 Stearate, Sodium Carbomer, Cetearyl Glucoside, Tocopheryl Acetate, Chlorphenesin, Hydrolyzed Soy Protein, Caprylyl Glycol, Sodium Acrylates C10-30 Alkyl Acrylate Crosspolymer, Escin, Phenoxyethanol, Sodium Citrate, Beta-Sitosterol, Biosaccharide Gum-1, Polyquaternium-51, Sodium Polyacrylate, Adenosine, Sodium Hyaluronate, Phytic Acid, Polysorbate 20, Ethylhexylglycerin, Hydrochloric Acid, Tocopherol, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Sodium Benzoate, Citric Acid

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.