# Cetaphil Healthy Radiance Renewing Cream for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/p/cetaphil/healthy-radiance-renewing-cream/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Cetaphil](https://lovi.care/skincare/brands/cetaphil)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/best/moisturizers)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other moisturizers fit it better.

## Why this fit

- Offers moderate suitability for your combination skin, as niacinamide helps regulate oil production and glycerin provides essential hydration, though it may not fully address all your concerns.
- The inclusion of phenylethyl resorcinol and sodium hyaluronate offers general brightening and moisturizing benefits, supporting overall skin health.
- The product is safe for your skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/cetaphil/healthy-radiance-renewing-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/p/cetaphil/healthy-radiance-renewing-cream/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/p/cetaphil/healthy-radiance-renewing-cream/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/p/cetaphil/healthy-radiance-renewing-cream/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/p/cetaphil/healthy-radiance-renewing-cream/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/p/cetaphil/healthy-radiance-renewing-cream/for/dark-spots): Superior
- [Mature skin](https://lovi.care/skincare/p/cetaphil/healthy-radiance-renewing-cream/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/p/cetaphil/healthy-radiance-renewing-cream/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/p/cetaphil/healthy-radiance-renewing-cream/for/oily-acne-prone-skin): Average

## Key ingredients

Gentlebright Complex, Niacinamide, Bakuchiol, Sodium Hyaluronate, Phenylethyl Resorcinol

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Nano-microneedle-assisted phenylethyl resorcinol significantly reduced the melanin index in infraorbital dark circles compared to baseline and topical-only treatment in 20 female participants without serious adverse effects. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/32783330/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical 2% niacinamide significantly decreased sebum excretion rate in Japanese individuals and casual sebum levels in Caucasian individuals compared to placebo or baseline. ([Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 4% nicotinamide and 1% clindamycin gels showed similar overall efficacy in reducing acne grade in patients with moderate inflammatory facial acne vulgaris over 8 weeks, with nicotinamide being more effective for oily skin and clindamycin for non-oily skin. ([International Journal of Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23786503/))
- Topical nicotinamide protected against immunosuppression caused by UVB, longwave UVA, and single and repeated solar-simulated UV exposures in healthy volunteers compared to vehicle. ([The British Journal of Dermatology, 2009](https://pubmed.ncbi.nlm.nih.gov/19804594/))
- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- A dermocosmetic containing bakuchiol, Ginkgo biloba extract, and mannitol improves inflammatory lesions, Investigator Global Assessment, and seborrhea intensity when added to adapalene 0.1% gel in patients with acne vulgaris. ([Clinical, Cosmetic and Investigational Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25914553/))
- Topical application of a serum containing supramolecular Bakuchiol and Terminalia chebula extract significantly improved barrier function, reduced redness and sensitivity, and improved wrinkles and elasticity in 34 Chinese subjects with sensitive skin after 28 days. ([Health Science Reports, 2025](https://pubmed.ncbi.nlm.nih.gov/41424674/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## What reviewers say

Users with dull or uneven skin tones generally report that this cream provides deep hydration and a noticeable "glow" without feeling heavy, thanks to its souffle-like texture. While many with sensitive skin praise its gentleness, a subset of users experienced immediate burning or stinging sensations, and results regarding the fading of dark spots were mixed, with some seeing improvements and others noticing no change.

- Liked: Deep hydration (mostly mentioned)
- Liked: Lightweight, soufflé texture (often mentioned)
- Liked: Brightens complexion (sometimes noted)
- Liked: Gentle on sensitive skin (sometimes noted)
- Disliked: Burning/stinging sensation (sometimes noted)
- Disliked: Ineffective on dark spots (rarely noted)
- Disliked: Medicinal/unpleasant smell (rarely noted)
- Disliked: Small product quantity (rarely noted)

## How to apply

- Use this moisturizer in your AM and PM routine every day to control shine. Always pair with SPF in the morning.
- Apply this moisturizer after your cleanser and toner, right before your morning SPF.
- Gently press a small amount of the moisturizer into your skin and avoid harsh rubbing. Let it ⏳absorb for a minute.
- Apply the moisturizer on slightly damp skin to help it lock in moisture better. This keeps your combination skin balanced.
- Avoid the eye area when applying the moisturizer. Do a patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Cetaphil Healthy Radiance Renewing Cream work for combination skin?

This cream works moderately well for combination skin, as niacinamide helps control oily shine and glycerin provides essential hydration. Because other products may fit this skin type better, a treatment of this type needs targeted brightening ingredients and balanced hydration to manage oily zones while nourishing dry areas without feeling heavy.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this cream a good fit for combination skin?

Niacinamide helps regulate oil production and glycerin provides essential hydration for combination skin. Phenylethyl resorcinol and sodium hyaluronate offer general brightening and moisturizing benefits to support overall skin health. Combination skin needs ingredients that reduce oily shine and target hydration and brightness without causing irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Gentlebright Complex do for combination skin?

Gentlebright Complex helps brighten dark spots and even out combination skin by targeting unwanted pigment. It is unlikely to cause irritation when used as directed in your daily routine.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### What does Niacinamide do for combination skin?

Niacinamide helps balance oily areas by reducing excess shine and pore size while keeping dry patches hydrated and smooth. It also works to calm redness and even out skin tone, making it very suitable for combination skin.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Where does this cream go in a skincare routine for combination skin?

This moisturizing treatment goes near the end of your evening routine, after your cleanser, toner, and treatment. Combination skin needs a product with niacinamide and glycerin to balance oil and hydration without feeling heavy.
Sources: [International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/31461548/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this cream with retinol, and in what order?

You can use this cream alongside retinol to help keep your skin comfortable and hydrated while you use strong treatments. Apply your retinol first, let it sink in, and then smooth this moisturizer over top to lock in hydration and help prevent dryness.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this cream?

You can use this moisturizing treatment twice daily as part of your morning and evening routines. Regular application helps improve skin hydration, brightness, and texture, while supporting overall skin health.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/)

### Can this cream clog pores, cause breakouts or purging for combination skin?

This cream is unlikely to clog pores or cause breakouts for combination skin, as it has a safe profile with no harsh ingredients. However, to truly balance combination skin without breakouts, a product of this type needs lightweight hydration alongside oil-controlling ingredients like niacinamide.

### Can I use this cream around the eyes or on my body?

You can use this moisturizing treatment safely on the body and around the eyes, though it is primarily designed for facial care. A product of this type needs lightweight hydrators like glycerin and soothing ingredients to care for thin or body skin without feeling heavy.

### Is this cream fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (alcohol).

## Alternatives for combination skin

- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/combination-skin) — Superior fit — $15.50 at Amazon
- [Drunk Elephant Protini Polypeptide Cream](https://lovi.care/skincare/p/drunk-elephant/protini-polypeptide-cream/for/combination-skin) — Superior fit — $49.95 at Amazon
- [The Ordinary Natural Moisturizing Factors + HA](https://lovi.care/skincare/p/the-ordinary/natural-moisturizing-factors-ha/for/combination-skin) — High fit — $12.50 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — $28.08 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — $25.60 at Amazon
- SPF: [CeraVe AM Facial Moisturizing Lotion](https://lovi.care/skincare/p/cerave/am-facial-moisturizing-lotion-spf-30/for/combination-skin) — Superior fit — $14.97 at Amazon

## Where to buy

No store in United States has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Propanediol, Dimethicone, Tricaprylin, Myristyl Myristate, Cetyl Alcohol, Niacinamide, Glyceryl Stearate Se, Peg-100 Stearate, C12-15 Alkyl Benzoate, Bakuchiol, Silica, Phenoxyethanol, Pentaerythrityl Tetraethylhexanoate, Ammonium Acryloydimethyltaurate Vp Copolymer, Behenyl Alcohol, Phytosteryl Octyldodecyl Lauroyl Glutamate, Sorbitan Tristearate, Isostearic Acid, Stearyl Alcohol, Alcohol, Ethylhexylglycerin, Phenylethyl Resorcinol, Disodium Edta, Malva Sylvestris Stem Extract Flower Leaf, Peppermint Leaf Extract, Primula Veris Flower Extract, Alchemilla Vulgaris Stem Extract Flower Leaf, Veronica Officinalis Stem Extract Flower Leaf, Melissa Officinalis Leaf Extract, Achillea Millefolium Stem Extract Flower Leaf, Citric Acid, Sodium Hyaluronate, Sodium Hydroxide
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/cetaphil/healthy-radiance-renewing-cream/for/combination-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/cetaphil/healthy-radiance-renewing-cream/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/cetaphil/healthy-radiance-renewing-cream/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/cetaphil/healthy-radiance-renewing-cream/for/combination-skin
- France: https://lovi.care/skincare/fr/p/cetaphil/healthy-radiance-renewing-cream/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/cetaphil/healthy-radiance-renewing-cream/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/cetaphil/healthy-radiance-renewing-cream/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/cetaphil/healthy-radiance-renewing-cream/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/cetaphil/healthy-radiance-renewing-cream/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/cetaphil/healthy-radiance-renewing-cream/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/cetaphil/healthy-radiance-renewing-cream/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/cetaphil/healthy-radiance-renewing-cream/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/cetaphil/healthy-radiance-renewing-cream/for/combination-skin