# Centellian 24 Madeca Cream for acne-prone skin

**Lovi Fit: High fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/p/centellian-24/madeca-cream/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Centellian 24](https://lovi.care/skincare/brands/centellian-24)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/best/moisturizers)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for acne-prone skin; a few moisturizers fit it even better.

## Why this fit

- Offers moderate benefits for your combination skin, as Centella Asiatica Extract and Madecassoside provide anti-inflammatory action and support barrier repair, which is helpful for your acne and breakouts.
- Glycerin and Hyaluronic Acid offer general hydration and soothing effects suitable for your skin type and concerns.
- The product is safe for your acne-prone skin, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/centellian-24/madeca-cream/for/oily-skin): Caution
- [Dry skin](https://lovi.care/skincare/p/centellian-24/madeca-cream/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/p/centellian-24/madeca-cream/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/p/centellian-24/madeca-cream/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/p/centellian-24/madeca-cream/for/acne-prone-skin): High (this page)
- [Skin with dark spots](https://lovi.care/skincare/p/centellian-24/madeca-cream/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/p/centellian-24/madeca-cream/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/p/centellian-24/madeca-cream/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/p/centellian-24/madeca-cream/for/oily-acne-prone-skin): Average

## Key ingredients

Centella Asiatica Extract, Madecassoside, Teca Extract Titrated Of Centella Asiatica Extract

## What the research says

- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Treatment with an asiaticoside-containing cream applied twice daily for 12 weeks significantly improved periorbital wrinkles in 65% of 27 female volunteers compared to a vehicle control cream. ([International Journal of Cosmetic Science, 2008](https://pubmed.ncbi.nlm.nih.gov/18452433/))

## What reviewers say

This moisturizer is highly praised for its ability to repair damaged skin barriers and provide a radiant glow, effectively soothing sensitive, dry, or mature skin and reducing redness. However, its rich, ointment-like texture and strong herbal scent may not be suitable for individuals with oily or acne-prone skin.

- Liked: Deeply hydrating (mostly mentioned)
- Liked: Improves texture (often mentioned)
- Liked: Soothing and calming (often mentioned)
- Disliked: Strong herbal scent (often mentioned)
- Liked: Rich but absorbent (sometimes noted)
- Disliked: Heavy for oily skin (sometimes noted)
- Disliked: Confusing versions (rarely noted)
- Disliked: Potential breakouts (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Centellian 24 Madeca Cream a great fit for acne-prone skin?

CENTELLIAN 24 Madeca Cream is a great fit for acne-prone skin because Centella Asiatica Extract and Madecassoside help calm redness and breakouts while supporting your skin barrier. Glycerin and Hyaluronic Acid add gentle hydration, and the formula is unlikely to cause irritation.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Which ingredients make this cream a good fit for acne-prone skin?

Centella Asiatica Extract and Madecassoside make this cream a great fit for your acne-prone skin because they help calm inflammation and repair your skin barrier. Glycerin and Hyaluronic Acid add gentle hydration, while the absence of harsh ingredients means the product is unlikely to cause irritation.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### What does Centella Asiatica Extract do for acne-prone skin?

Centella asiatica extract helps calm angry skin, reduces redness, and supports healing for breakouts. It is unlikely to cause irritation and may improve overall skin clarity when used consistently.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/)

### What does Madecassoside do for acne-prone skin?

Madecassoside helps acne-prone skin by calming redness, reducing acne breakouts, and repairing the skin barrier to keep it healthy. It may also lower water loss and soothe irritation when used consistently in your routine.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Bioengineering, 2025](https://pubmed.ncbi.nlm.nih.gov/41007180/)

### Where does this cream go in a skincare routine for acne-prone skin?

This moisturizing treatment goes in the evening routine after your cleansing toner and before your moisturizer. Using a moisturizer helps calm breakouts and repair the skin barrier without causing irritation.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Can I use it with retinol, and in what order?

You can use it with retinol by applying your retinol first and following with this moisturizer to help calm your skin and lower the chances of irritation. Using a soothing moisturizer alongside active treatments supports your skin barrier and improves comfort.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [The Journal of Dermatological Treatment, 2016](https://pubmed.ncbi.nlm.nih.gov/26293170/)

### How often should I use this cream?

You can use this moisturizing treatment twice a day as part of your morning and evening routine. Regular daily application helps improve skin moisture and calm breakouts without causing irritation.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can it clog pores, cause breakouts or purging for acne-prone skin?

CENTELLIAN 24 Madeca Cream is unlikely to clog pores or cause breakouts on acne-prone skin because it contains soothing components and lacks harsh ingredients that trigger irritation. The formula helps calm breakouts with Centella Asiatica Extract and Madecassoside, though a low number of reviewers mention potential breakouts.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Can I use this cream around the eyes or on my body?

You can use this moisturizing treatment safely on the body, but take care near the eyes because the skin there is much thinner and more sensitive. The soothing and calming ingredients make it gentle enough for general use, though testing a small patch first is always a good idea.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for acne-prone skin

- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/acne-prone-skin) — Superior fit — $15.50 at Amazon
- [Drunk Elephant Protini Polypeptide Cream](https://lovi.care/skincare/p/drunk-elephant/protini-polypeptide-cream/for/acne-prone-skin) — Superior fit — $49.95 at Amazon
- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/p/cosrx/advanced-snail-96-mucin-power-essence/for/acne-prone-skin) — Superior fit — $15.88 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/p/cerave/foaming-facial-cleanser/for/acne-prone-skin) — Superior fit — $15.97 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/p/some-by-mi/snail-truecica-miracle-repair-toner/for/acne-prone-skin) — Superior fit — $15.60 at Amazon
- SPF: [d'Alba Piedmont Waterfull Mild Sunscreen](https://lovi.care/skincare/p/d-alba/piedmont-waterfull-mild-sunscreen/for/acne-prone-skin) — Superior fit — $15.99 at Amazon

## Where to buy

- Amazon.com: $28.98 (https://www.amazon.com/dp/B0DFY92NDB?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Centella Asiatica Extract, Madecassoside, Teca Extract Titrated Of Centella Asiatica Extract, Glycerin, Butylene Glycol, Caprylic Capric Triglyceride, Cetearyl Alcohol, Dimethicone, Hyaluronic Acid, Panthenol, Allantoin
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/centellian-24/madeca-cream/for/acne-prone-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/centellian-24/madeca-cream/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/centellian-24/madeca-cream/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/centellian-24/madeca-cream/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/centellian-24/madeca-cream/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/centellian-24/madeca-cream/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/centellian-24/madeca-cream/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/centellian-24/madeca-cream/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/centellian-24/madeca-cream/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/centellian-24/madeca-cream/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/centellian-24/madeca-cream/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/centellian-24/madeca-cream/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/centellian-24/madeca-cream/for/acne-prone-skin