# Caudalie Vinoperfect Radiance Serum for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/p/caudalie/vinoperfect-radiance-serum/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Caudalie](https://lovi.care/skincare/brands/caudalie)
Category: [Serums and treatments](https://lovi.care/skincare/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other serums fit it better.

## Why this fit

- Offers moderate brightening for your combination skin due to Palmitoyl Grapevine Shoot Extract, while glycerin and squalane provide hydration that is supportive but not directly targeted at your oily shine concerns.
- The formula is generally safe for your combination skin, as it lacks harsh ingredients and is unlikely to cause irritation.
- While it offers general skincare benefits, it does not provide stronger ingredients for significant oil control, which is your main goal.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/caudalie/vinoperfect-radiance-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/p/caudalie/vinoperfect-radiance-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/p/caudalie/vinoperfect-radiance-serum/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/p/caudalie/vinoperfect-radiance-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/p/caudalie/vinoperfect-radiance-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/p/caudalie/vinoperfect-radiance-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/p/caudalie/vinoperfect-radiance-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/p/caudalie/vinoperfect-radiance-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/p/caudalie/vinoperfect-radiance-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Viniferine, Palmitoyl Grapevine Shoot Extract, Squalane, Glycerin, Tocopheryl Acetate

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A combination of Vitis vinifera shoot extract and a biotechnological extract demonstrated significant in vitro and in vivo antioxidant effects and improved clinical signs of photoaged skin in female subjects after a 4-week application. ([Journal of Drugs in Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17691204/))
- Pre-treatment with Vitis vinifera L. water extract (100 ΓΙg/mL) demonstrated antioxidant and scavenger activity against UV-A radiation and exerted an anti-mutagenic effect by maintaining apoptosis in UV-A and UV-B irradiated human keratinocytes (HaCaT). ([Journal of Photochemistry and Photobiology. B, Biology, 2020](https://pubmed.ncbi.nlm.nih.gov/32028189/))
- A water extract from grapevine leaves inhibited proinflammatory-induced interleukin-8 and vascular endothelial growth factor secretion in human keratinocytes compared to untreated challenged cells. ([Antioxidants, 2019](https://pubmed.ncbi.nlm.nih.gov/31100904/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40642809/))
- Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate. ([Contemporary Clinical Trials Communications, 2021](https://pubmed.ncbi.nlm.nih.gov/34471722/))
- Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590207/))

## Why other serums fit combination skin better

- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))
- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))

## What reviewers say

Based on a very large amount of data, this serum is highly regarded for its ability to gently brighten and even skin tone, making it a suitable option for sensitive skin and addressing concerns like dark spots and redness. Users frequently note its pleasant texture and hydrating finish, though it's important to note that consistent, long-term use is often required to see results. Some users also report a sticky sensation after application and find the product to be expensive.

- Liked: Brightens & evens tone (mostly mentioned)
- Liked: Gentle & non-irritating (mostly mentioned)
- Disliked: High price (mostly mentioned)
- Liked: Pleasant texture (often mentioned)
- Disliked: Slow results (often mentioned)
- Liked: Fresh scent (sometimes noted)
- Liked: Hydrating finish (sometimes noted)
- Disliked: Sticky finish (sometimes noted)
- Disliked: Rare breakouts (rarely noted)
- Disliked: Scent dislike (rarely noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Caudalie Vinoperfect Radiance Serum work for combination skin?

This serum works moderately well for combination skin because it offers gentle brightening and supportive hydration, though it lacks stronger ingredients for significant oil control. To fit this skin better, a product of this type needs effective ingredients like niacinamide, propolis, or zinc PCA that provide excellent benefits, enhance radiance, and regulate oiliness without causing excess oiliness or dryness.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for combination skin?

Palmitoyl Grapevine Shoot Extract makes this serum a good fit by offering moderate brightening for your combination skin, while glycerin and squalane provide hydration. Because it lacks stronger ingredients for significant oil control, a treatment of this type needs ingredients like niacinamide, zinc PCA, or propolis to regulate oiliness and manage oily shine.

### What does Viniferine do for combination skin?

Viniferine helps combination skin by smoothing out uneven spots and protecting against daily damage with powerful antioxidants. It is unlikely to feel heavy or clog your pores while keeping your skin looking bright and fresh.
Sources: [Journal of Food and Drug Analysis, 2021](https://pubmed.ncbi.nlm.nih.gov/35696226/), [Recent Advances in Food, Nutrition & Agriculture, 2025](https://pubmed.ncbi.nlm.nih.gov/39108105/)

### Where does it go in a skincare routine for combination skin?

This treatment goes in your evening routine after cleansing and toning, and before moisturizing. To better fit combination skin, this type of product needs stronger ingredients for significant oil control.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first and following with your retinol. This routine is unlikely to cause irritation since the formula lacks harsh ingredients, and a supportive routine helps keep the skin calm.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/)

### How often should I use it?

You can use this treatment in your evening routine for simplicity and extra safety around sun exposure. It is unlikely to cause irritation on your combination skin since it lacks harsh ingredients.

### Can this serum clog pores, cause breakouts or purging for combination skin?

This serum is unlikely to cause breakouts or clog pores on combination skin, as it lacks harsh ingredients and has a safe profile for your skin type. However, because it does not target oily shine, combination skin usually needs lightweight, oil-balancing ingredients like niacinamide or salicylic acid to help keep pores clear.

### Is it fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum).

## Alternatives for combination skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/combination-skin) — Superior fit — $16.75 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin) — Superior fit — $28.88 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/p/augustinus-bader/the-serum/for/combination-skin) — Superior fit — $200.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — $28.08 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — $25.60 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — $18.99 at Amazon

## Where to buy

- Amazon.com: $82.00 (https://www.amazon.com/dp/B0CX5B5VTX?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Butylene Glycol, Glycerin, Coco-Caprylate Caprate, Squalane, Palmitoyl Grapevine Shoot Extract, Polyglyceryl-3 Distearate, Bisabolol, Glyceryl Stearate, Xanthan Gum, Caprylyl Glycol, Microcrystalline Cellulose, Polyacrylate Crosspolymer-6, Potassium Sorbate, Glyceryl Stearate Citrate, Citric Acid, Sodium Phytate, Sodium Hydroxide, Parfum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/caudalie/vinoperfect-radiance-serum/for/combination-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/caudalie/vinoperfect-radiance-serum/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/caudalie/vinoperfect-radiance-serum/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/caudalie/vinoperfect-radiance-serum/for/combination-skin
- France: https://lovi.care/skincare/fr/p/caudalie/vinoperfect-radiance-serum/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/caudalie/vinoperfect-radiance-serum/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/caudalie/vinoperfect-radiance-serum/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/caudalie/vinoperfect-radiance-serum/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/caudalie/vinoperfect-radiance-serum/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/caudalie/vinoperfect-radiance-serum/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/caudalie/vinoperfect-radiance-serum/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/caudalie/vinoperfect-radiance-serum/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/caudalie/vinoperfect-radiance-serum/for/combination-skin