# BY ECOM Heartleaf Ampoule for dry skin

**Lovi Fit: Average fit for dry skin.**
Dry Skin Fit: Average · Effectiveness: Average · Safety: Low Risk.

Page: https://lovi.care/skincare/p/by-ecom/heartleaf-ampoule/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: BY ECOM
Category: [Serums and treatments](https://lovi.care/skincare/best/serums)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry skin; other serums fit it better.

## Why this fit

- Offers moderate suitability for your dry skin, as glycerin and beta-glucan provide humectant action, but it lacks sufficient emollient and occlusive ingredients for optimal hydration.
- The presence of houttuynia cordata extract and willow bark extract offers excellent treatment for acne-prone skin by decongesting pores and reducing blemishes.
- The formula is generally safe for your dry skin, though the inclusion of alcohol carries a slight risk of irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/by-ecom/heartleaf-ampoule/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/p/by-ecom/heartleaf-ampoule/for/dry-skin): Average (this page)
- [Combination skin](https://lovi.care/skincare/p/by-ecom/heartleaf-ampoule/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/p/by-ecom/heartleaf-ampoule/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/p/by-ecom/heartleaf-ampoule/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/p/by-ecom/heartleaf-ampoule/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/p/by-ecom/heartleaf-ampoule/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/p/by-ecom/heartleaf-ampoule/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/p/by-ecom/heartleaf-ampoule/for/oily-acne-prone-skin): High

## Key ingredients

Heartleaf Extract, Sodium Hyaluronate, Glycerin, Centella Asiatica Extract, Curcuma Longa Root Extract

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Skin care regimens containing beta-glucan improved hemoglobin index, skin hydration, and transepidermal water loss compared to vehicle control in 20 patients undergoing fractional laser therapy. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/))
- A botanical face cleanser with hops and willow bark extract continuously reduced skin sebum levels without reactive seborrhea after treatment in 21 healthy volunteers compared to a sodium laureth sulfate cleanser, with neither cleanser causing skin irritation. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30022595/))
- Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate can be used safely in cosmetic formulations at concentrations up to 5%, and Benzyl Alcohol is safe up to 10% in hair dyes, despite causing nonimmunologic contact reactions. ([International Journal of Toxicology, 2001](https://pubmed.ncbi.nlm.nih.gov/11766131/))
- Quercetin phospholipids 1% cream significantly reduced UV-, histamine-, and chemical-induced skin erythema (-10.05%) and mean wheal diameter in 30 healthy human volunteers, showing comparable efficacy to 1% dexchlorpheniramine cream. ([Clinical, Cosmetic and Investigational Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/27013898/))
- Quercetin-loaded niosomes formulated with Span60-RH40 at a 9:11 mass ratio improved quercetin solubility, photostability, sustained release, and transdermal penetration, yielding a skin retention 2.95 times higher than quercetin solution. ([Molecules, 2019](https://pubmed.ncbi.nlm.nih.gov/31238562/))
- Optimized rutin-loaded glycerosomes formulated into a nanosunscreen gel demonstrated sustained drug release, greater skin permeation, good antioxidant activity, and better epidermal retention compared to the dermis, indicating high safety, stability, and sun protection factor values for topical administration. ([Gels, 2023](https://pubmed.ncbi.nlm.nih.gov/37754433/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Topical application of curcumin or turmeric treats various skin conditions by leveraging antioxidant, anti-inflammatory, and antimicrobial properties. ([Skin Pharmacology and Physiology, 2023](https://pubmed.ncbi.nlm.nih.gov/38008088/))
- Topical formulations of curcumin target oxidative damage and inflammation to improve wound healing in animal models. ([Drug Discovery Today, 2017](https://pubmed.ncbi.nlm.nih.gov/28711364/))
- A curcumin-loaded spanlastic anti-aging gel utilizing formula F5 incorporated into 2% HPMC E50 demonstrated sustained release action, compatibility, and the ability to penetrate skin layers to a depth of about 112.5 um without signs of irritation. ([Saudi Pharmaceutical Journal, 2024](https://pubmed.ncbi.nlm.nih.gov/38178851/))

## Why other serums fit dry skin better

- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))
- Treatment with 14% ferulic acid and 12% l-ascorbic acid significantly reduced pigmentation and erythema while improving hydration and elasticity in 20 women with photoaged skin, with neither acid proving definitively more effective overall though ascorbic acid showed slightly greater skin lightening. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/34877760/))

## What reviewers say

Users with oily and acne-prone skin frequently report that this ampoule effectively soothes inflammation and provides a cooling sensation. A moderate number of users also find it hydrating and notice some pore refining effects. A significant minority of reviewers mention a sticky finish and a strong alcohol scent, with some experiencing irritation or breakouts. Results for pore shrinking are mixed.

- Liked: Hydrating texture (often mentioned)
- Liked: Soothing and calming (often mentioned)
- Liked: Aesthetic packaging (sometimes noted)
- Liked: Pore refining (sometimes noted)
- Disliked: Alcohol scent (sometimes noted)
- Disliked: Pore claims weak (sometimes noted)
- Disliked: Sticky finish (sometimes noted)
- Disliked: Caused irritation (rarely noted)

## How to apply

- Apply this serum PM, starting 3×/week and working up to daily use as your skin adjusts.
- Place the serum after cleansing and toner, but right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on slightly damp skin to help lock in extra moisture.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does BY ECOM Heartleaf Ampoule work for dry skin?

This product works moderately well for your dry skin because glycerin and beta-glucan help draw in moisture, though it lacks enough rich softeners and sealing ingredients to lock that hydration in. Dry skin of this type needs rich soothing ingredients, skin barrier support, ceramides, and nourishing vitamins to keep it properly hydrated and healthy.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/)

### Which ingredients make this ampoule a good fit for dry skin?

Glycerin and beta-glucan make this ampoule work for dry skin by drawing in moisture, though this dry skin type needs rich sealing ingredients and skin-softening oils to lock it in.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/)

### What does Heartleaf Extract do for dry skin?

Heartleaf extract helps calm irritated dry skin by reducing redness and inflammation while supporting the skin's moisture barrier. For very dry skin, a product of this type needs added rich oils and butters to deeply soften and lock in hydration.
Sources: [International Journal of Biological Macromolecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40393586/)

### What does Hyaluronic Acid do for dry skin?

Hyaluronic acid draws moisture into dry skin, giving an immediate and lasting boost in hydration that helps smooth out fine lines and soften rough patches. It is very gentle and unlikely to cause irritation while improving overall skin smoothness and plumpness.
Sources: [Dermatology and Therapy, 2021](https://pubmed.ncbi.nlm.nih.gov/34176098/), [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/)

### Where does this ampoule go in a skincare routine for dry skin?

This treatment goes in the evening routine after cleansing and before moisturizing, though some can also be used in the morning or twice a day. This product works for dry skin, but because it lacks sufficient rich and sealing ingredients, dry skin needs additional soothing and softening creams and oils to lock in moisture.

### Can I use this ampoule with retinol, and in what order?

You can use this ampoule with retinol by applying the ampoule first to help hydrate, followed by your retinol once it absorbs. Dry skin also needs rich emollient and occlusive ingredients to properly lock in that moisture.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/)

### How often should I use this ampoule?

You can use this ampoule in your evening routine. A product of this type for dry skin needs rich, softening ingredients and protective creams to lock in moisture.

### Can this ampoule clog pores, cause breakouts or purging for dry skin?

This ampoule is unlikely to clog your pores or cause breakouts, as ingredients like willow bark extract help decongest pores and reduce blemishes. However, dry skin of this type needs richer, nourishing ingredients that seal in moisture to keep skin fully hydrated and soft.
Sources: [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30022595/)

### Is this ampoule fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (alcohol).

## Alternatives for dry skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/dry-skin) — Superior fit — $16.75 at Amazon
- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/dry-skin) — Superior fit — $53.00 at Amazon
- [ma:nyo Bifida Biome Complex Ampoule](https://lovi.care/skincare/p/ma-nyo/bifida-biome-complex-ampoule/for/dry-skin) — Superior fit — $19.90 at Amazon

## Pairs well with

- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — $19.99 at Amazon
- Hydrating Toner: [Pyunkang Yul Calming Deep Moisture Toner](https://lovi.care/skincare/p/pyunkang-yul/calming-deep-moisture-toner/for/dry-skin) — Superior fit — $16.99 at Amazon
- Moisturizer: [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/dry-skin) — Superior fit — $22.00 at Amazon

## Where to buy

No store in United States has a checked price for this product, so the page shows none.

## Ingredients

Houttuynia Cordata Extract, Methylpropanediol, Butylene Glycol, Glycerin, 2-Hexanediol, Cyclohexasiloxane, Laminaria Japonica Extract, Eclipta Prostrata Leaf Extract, Camellia Sinensis Leaf Extract, Centella Asiatica Extract, Melia Azadirachta Flower Extract, Melia Azadirachta Leaf Extract, Lemon Fruit Extract, Monarda Didyma Leaf Extract, Citrus Aurantium Dulcis Fruit Extract, Anthemis Nobilis Flower Extract, Avena Sativa Kernel Extract Oat Kernel Extract, Pteris Multifida Extract, Cynara Scolymus Leaf Extract, Curcuma Longa Root Extract, Ocimum Sanctum Leaf Extract, Chestnut Shell Extract, Piper Methysticum Stem Extract Root Leaf, Panax Ginseng Extract Berry, Corallina Officinalis Extract, Willow Bark Extract, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Paeonia Albiflora Root Extract, Cnidium Officinale Root Extract, Pueraria Thunbergiana Root Extract, Portulaca Oleracea Extract, Enantia Chlorantha Bark Extract, Persea Gratissima Fruit Extract Avocado Fruit Extract, Hydrogenated Lecithin, Sodium Hyaluronate, Water-Soluble Collagen, Aloe Barbadensis Leaf Juice, Sh-Polypeptide-19, Ammonium Acryloyldimethyltaurate Vp Copolymer, Xanthan Gum, Water, Carbomer, Fructooligosaccharides, Beta-Glucan, Disodium Edta, Tromethamine, Polyquaternium-51, Hydrolyzed Hyaluronic Acid, Alcohol, Lecithin, Pistacia Lentiscus Gum, Maltodextrin, Sodium Phosphate, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Oleanolic Acid, Ethylhexylglycerin, Caprylyl Glycol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/by-ecom/heartleaf-ampoule/for/dry-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/by-ecom/heartleaf-ampoule/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/by-ecom/heartleaf-ampoule/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/by-ecom/heartleaf-ampoule/for/dry-skin
- France: https://lovi.care/skincare/fr/p/by-ecom/heartleaf-ampoule/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/by-ecom/heartleaf-ampoule/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/by-ecom/heartleaf-ampoule/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/by-ecom/heartleaf-ampoule/for/dry-skin
- Canada: https://lovi.care/skincare/ca/p/by-ecom/heartleaf-ampoule/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/by-ecom/heartleaf-ampoule/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/by-ecom/heartleaf-ampoule/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/by-ecom/heartleaf-ampoule/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/by-ecom/heartleaf-ampoule/for/dry-skin