# Biossance Squalane + Probiotic Gel Moisturizer for sensitive skin

**Lovi Fit: High fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/p/biossance/squalane-probiotic-gel-moisturizer/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Biossance](https://lovi.care/skincare/brands/biossance)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/best/moisturizers)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for sensitive skin; a few moisturizers fit it even better.

## Why this fit

- Highly suitable for your normal skin, this moisturizer effectively hydrates with squalane and glycerin, supporting your skin's natural moisture balance and barrier resilience.
- Allantoin and bisabolol offer moderate benefits for your redness and irritation by soothing and calming the skin.
- The formulation is safe for your normal skin with sensitivity, as it lacks prohibited or harsh ingredients and poses no risk of irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/biossance/squalane-probiotic-gel-moisturizer/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/p/biossance/squalane-probiotic-gel-moisturizer/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/p/biossance/squalane-probiotic-gel-moisturizer/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/p/biossance/squalane-probiotic-gel-moisturizer/for/sensitive-skin): High (this page)
- [Acne-prone skin](https://lovi.care/skincare/p/biossance/squalane-probiotic-gel-moisturizer/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/p/biossance/squalane-probiotic-gel-moisturizer/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/p/biossance/squalane-probiotic-gel-moisturizer/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/p/biossance/squalane-probiotic-gel-moisturizer/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/p/biossance/squalane-probiotic-gel-moisturizer/for/oily-acne-prone-skin): High

## Key ingredients

Squalane, Probiotics, Glycerin, Lactococcus Lysate Ferment, Zingiber Officinale Root Extract

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- A 1-year clinical study on human facial skin demonstrated that Zingiber officinale (L.) Rose extract inhibits the UV-induced decrease in skin elasticity and prevents or improves wrinkle formation around the eye. ([Archives of Dermatological Research, 2008](https://pubmed.ncbi.nlm.nih.gov/17968573/))
- Ginger extract transethosomal hydrogel improved skin permeability, sustained drug release, and exhibited significant inhibition of edema swelling along with reduced reactive oxygen species and prostaglandin E2 compared to free ginger extract hydrogel and ketoprofen gel in a rat-paw edema model. ([International Journal of Nanomedicine, 2023](https://pubmed.ncbi.nlm.nih.gov/36945254/))
- Topical delivery of ginger extract-loaded nanoemulsions significantly reduced arthritic symptoms, paw edema inhibition by 27.7%, and inflammatory cytokines in RA-induced rats compared to the negative control. ([Journal of Pharmaceutical Sciences, 2023](https://pubmed.ncbi.nlm.nih.gov/36773928/))

## What reviewers say

Based on a very large amount of data, this lightweight gel moisturizer is highly recommended for oily, combination, and sensitive skin types, effectively hydrating without pore clogging and visibly reducing redness. However, a significant number of recent reviews indicate dissatisfaction with a formula change, noting a stickier texture and less pleasant scent compared to the original. Dry skin types may find it insufficient for hydration, and some users express concerns about the price point. A small number of users have reported irritation or breakouts.

- Liked: Lightweight & fast absorbing (mostly mentioned)
- Liked: Balances oily skin (often mentioned)
- Liked: Calms redness & irritation (often mentioned)
- Disliked: Reformulation complaints (often mentioned)
- Liked: Excellent makeup base (sometimes noted)
- Disliked: Not hydrating enough (sometimes noted)
- Disliked: Price point (sometimes noted)
- Disliked: Irritation and breakouts (rarely noted)

## How to apply

- Use this soothing AM and PM routine every day to keep your normal skin calm. Always remember to apply SPF in the morning after your moisturizer.
- Apply your moisturizer after your toner in the morning, and after your serum in the evening. This step locks in hydration and protects your skin.
- Gently press a small amount of the moisturizer evenly across your face. Avoid rubbing to keep your sensitive skin happy and calm.
- You can apply this gentle formula on dry or slightly damp skin for the best comfort. It works wonderfully on clean skin to soothe redness and irritation.
- Do a patch test before your very first use to check your skin's reaction. Avoid getting the product directly into your eyes .
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Biossance Squalane + Probiotic Gel Moisturizer a great fit for sensitive skin?

This moisturizer is a great fit because it hydrates with squalane and glycerin to support your skin barrier, while allantoin and bisabolol help soothe and calm redness and irritation. It has a very safe profile for sensitive skin as it lacks harsh ingredients and poses no risk of irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this moisturizer a good fit for sensitive skin?

Squalane and glycerin make this moisturizer a good fit because they hydrate and support your skin barrier, while allantoin and bisabolol help calm redness and irritation. The formulation is safe for sensitive skin as it lacks harsh ingredients and is unlikely to cause irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Squalane do for sensitive skin?

Squalane helps calm sensitive skin by defending against everyday irritation and keeping it smooth and soft. It is unlikely to cause irritation and supports your skin barrier so it stays comfortable and hydrated.
Sources: [International Journal of Molecular Sciences, 2017](https://pubmed.ncbi.nlm.nih.gov/29280987/)

### What do Probiotics do for sensitive skin?

Probiotics help calm sensitive skin, reduce redness, and keep it moisturized by strengthening the skin barrier. Using them daily may also decrease skin reactivity and make your skin feel more comfortable.
Sources: [Scientific Reports, 2023](https://pubmed.ncbi.nlm.nih.gov/37803101/), [Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38186043/)

### Where does this moisturizer go in a skincare routine for sensitive skin?

This moisturizer goes as the final step of your evening routine to lock in hydration and support your skin barrier. It follows your cleansing, toning, and treatment steps.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/)

### Can I use this moisturizer with retinol, and in what order?

You can use this moisturizer with retinol by applying the retinol first, letting it absorb, and then following with the moisturizer to help calm and hydrate your skin. This type of routine layer is unlikely to cause irritation and may support your skin barrier while using stronger ingredients.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22648223/)

### How often should I use this moisturizer?

This moisturizer is a great fit for your sensitive skin and can be used daily as part of your morning and evening routine. Regular use helps keep skin hydrated while soothing redness and irritation, as the gentle formula supports your natural moisture balance.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this moisturizer clog pores, cause breakouts or purging for sensitive skin?

This moisturizer is unlikely to cause breakouts or clog pores on sensitive skin because it lacks harsh or prohibited ingredients that trigger irritation. It helps keep your skin calm and balanced while providing lightweight hydration.

### Can I use this moisturizer around the eyes or on my body?

This moisturizer is generally safe to apply around the eyes or on the body, though the skin there may respond differently due to varying thickness across body regions. The formulation is gentle and lacks harsh ingredients, making it unlikely to cause irritation on delicate areas.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/)

### Is this moisturizer fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for sensitive skin

- [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/sensitive-skin) — Superior fit — $22.00 at Amazon
- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/p/cosrx/advanced-snail-96-mucin-power-essence/for/sensitive-skin) — Superior fit — $15.88 at Amazon
- [COSRX Advanced Snail 92 All in One Cream](https://lovi.care/skincare/p/cosrx/advanced-snail-92-all-in-one-cream/for/sensitive-skin) — Superior fit — $16.50 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — $28.08 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/p/clarins/soothing-toning-lotion/for/sensitive-skin) — Superior fit — $28.05 at Amazon
- Moisturizer with Sun Protection: [innisfree Daily Mild Sunscreen](https://lovi.care/skincare/p/innisfree/daily-mild-sunscreen/for/sensitive-skin) — Superior fit — $18.00 at Amazon

## Where to buy

No store in United States has a checked price for this product, so the page shows none.

## Ingredients

Water, Squalane, Glycerin, Dimethicone, Pentylene Glycol, Ammonium Acryloyldimethyltaurate Vp Copolymer, Lactococcus Lysate Ferment, Caprylic Capric Triglyceride, Phenoxyethanol, Caprylyl Glycol, Dimethiconol, Chondrus Crispus Extract, Allantoin, Bisabolol, Glycine Soja Soybean Sterols, Linoleic Acid, Sodium Phytate, Lecithin, Sodium Hydroxide, Sodium Hyaluronate, Lactic Acid, Lepidium Sativum Extract Sprout, Sodium Chloride, Sodium Benzoate, Citric Acid, Zingiber Officinale Root Extract
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/biossance/squalane-probiotic-gel-moisturizer/for/sensitive-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/biossance/squalane-probiotic-gel-moisturizer/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/biossance/squalane-probiotic-gel-moisturizer/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/biossance/squalane-probiotic-gel-moisturizer/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/biossance/squalane-probiotic-gel-moisturizer/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/biossance/squalane-probiotic-gel-moisturizer/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/biossance/squalane-probiotic-gel-moisturizer/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/biossance/squalane-probiotic-gel-moisturizer/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/biossance/squalane-probiotic-gel-moisturizer/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/biossance/squalane-probiotic-gel-moisturizer/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/biossance/squalane-probiotic-gel-moisturizer/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/biossance/squalane-probiotic-gel-moisturizer/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/biossance/squalane-probiotic-gel-moisturizer/for/sensitive-skin