# Biossance Squalane + Omega Repair Cream for acne-prone skin

**Lovi Fit: Average fit for acne-prone skin.**
Combination Skin Fit: Average · Effectiveness: Average · Safety: Excellent.

Page: https://lovi.care/skincare/p/biossance/squalane-omega-repair-cream/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Biossance](https://lovi.care/skincare/brands/biossance)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/best/moisturizers)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for acne-prone skin; other moisturizers fit it better.

## Why this fit

- Offers moderate suitability for your combination skin, as squalane and glycerin provide emollient and humectant actions to hydrate and enhance barrier resilience without causing irritation. These ingredients are supportive for general skincare benefits but not specifically targeted for your acne, blemishes, and breakouts.
- While the formula lacks sufficient ingredients for optimal oil control on your oily areas, the presence of ceramides and squalane ensures a good safety profile by soothing the skin.
- The product is safe for your acne-prone skin due to the absence of harsh ingredients and the inclusion of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/biossance/squalane-omega-repair-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/p/biossance/squalane-omega-repair-cream/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/p/biossance/squalane-omega-repair-cream/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/p/biossance/squalane-omega-repair-cream/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/p/biossance/squalane-omega-repair-cream/for/acne-prone-skin): Average (this page)
- [Skin with dark spots](https://lovi.care/skincare/p/biossance/squalane-omega-repair-cream/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/p/biossance/squalane-omega-repair-cream/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/p/biossance/squalane-omega-repair-cream/for/dry-sensitive-skin): Superior
- [Oily acne-prone skin](https://lovi.care/skincare/p/biossance/squalane-omega-repair-cream/for/oily-acne-prone-skin): High

## Key ingredients

Squalane, Ceramide Np, Sodium Hyaluronate, Butyrospermum Parkii Butter Shea Butter, Euterpe Oleracea Sterols

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events. ([Lasers in Medical Science, 2025](https://pubmed.ncbi.nlm.nih.gov/41134387/))
- A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells. ([International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39528438/))

## Why other moisturizers fit acne-prone skin better

- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))
- A facial serum containing snail secretion filtrate, Calendula officinalis, and Glycyrrhiza glabra root extract significantly reduced inflammatory acne lesions compared to placebo in 66 participants with mild-to-moderate maskne over 12 weeks. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35763437/))

## What reviewers say

Many users love its luxurious, non-greasy texture and find it soothing for sensitive skin, also noting it works well as a makeup base. A significant portion of reviews consistently cite a distinct, unpleasant natural scent as a major drawback, despite the product's effective performance in plumping and smoothing skin texture. Some users also find the price point high and a minority with extremely dry skin felt it wasn't rich enough.

- Liked: Deep hydration (mostly mentioned)
- Disliked: Unpleasant scent (mostly mentioned)
- Liked: Non-greasy texture (often mentioned)
- Liked: Excellent makeup base (sometimes noted)
- Liked: Soothing for sensitive (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Not rich enough (rarely noted)
- Disliked: Packaging issues (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Biossance Squalane + Omega Repair Cream work for acne-prone skin?

Biossance Squalane + Omega Repair Cream works well for acne-prone skin by providing hydration and soothing the skin without causing irritation, though it lacks targeted ingredients for breakouts. To fit acne-prone skin better, a moisturizing treatment needs ingredients specifically targeted for acne and blemishes.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this cream a good fit for acne-prone skin?

Squalane and ceramides make this cream a safe fit by soothing your skin and supporting its barrier without causing irritation. However, a product for acne-prone skin also needs ingredients that specifically target blemishes and breakouts while helping to control oil.
Sources: [Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/)

### What does Squalane do for acne-prone skin?

Squalane may help keep acne-prone skin soft and smooth, but peroxidated forms can trigger inflammation in skin cells. For a better fit on acne-prone skin, products need non-clogging, soothing ingredients that balance oil without causing irritation.
Sources: [The Journal of Investigative Dermatology, 2006](https://pubmed.ncbi.nlm.nih.gov/16778793/)

### What do Ceramides do for acne-prone skin?

Ceramides help acne-prone skin by restoring a weak water barrier, which is often damaged and low in these protective lipids in people with acne. Using them helps reduce dryness, redness, and irritation caused by acne treatments while keeping the skin calm and smooth.
Sources: [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37276158/), [Archives of Dermatological Research, 1995](https://pubmed.ncbi.nlm.nih.gov/7763094/)

### Where does this cream go in a skincare routine for acne-prone skin?

This cream goes toward the end of your morning and evening routines as your moisturizer step, right after your hydrating toner and treatment. It keeps your skin soft and calm with a safe, gentle formula, though acne-prone skin needs a product that also provides targeted oil control and blemish-fighting ingredients.

### Can I use this cream with retinol, and in what order?

You can use this cream with retinol by applying the retinol first, letting it dry, and then smoothing on your moisturizer to help calm the skin. Using a barrier-supporting moisturizer alongside retinol is unlikely to cause irritation and may make your routine more comfortable.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this cream?

You can use this moisturizing treatment twice daily to keep your skin soft and hydrated. Daily application helps improve moisture and protects the skin barrier without causing irritation.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for acne-prone skin?

This cream is unlikely to clog pores or cause breakouts on your acne-prone skin because it avoids harsh ingredients and includes soothing components. However, because it lacks targeted ingredients for oil control, acne-prone skin generally needs lightweight hydrators and oil-balancing ingredients like salicylic acid or niacinamide to help keep breakouts clear.

### Can I use this cream around the eyes or on my body?

You can use this moisturizing treatment around the eyes and on the body because it is safe for the skin, but a product of this type needs lighter textures for very thin eye areas and richer hydration for dry body skin.

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for acne-prone skin

- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/acne-prone-skin) — Superior fit — $15.50 at Amazon
- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/p/cosrx/advanced-snail-96-mucin-power-essence/for/acne-prone-skin) — Superior fit — $15.88 at Amazon
- [Drunk Elephant Protini Polypeptide Cream](https://lovi.care/skincare/p/drunk-elephant/protini-polypeptide-cream/for/acne-prone-skin) — Superior fit — $49.95 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/p/cerave/foaming-facial-cleanser/for/acne-prone-skin) — Superior fit — $15.97 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/p/some-by-mi/snail-truecica-miracle-repair-toner/for/acne-prone-skin) — Superior fit — $15.60 at Amazon
- SPF: [d'Alba Piedmont Waterfull Mild Sunscreen](https://lovi.care/skincare/p/d-alba/piedmont-waterfull-mild-sunscreen/for/acne-prone-skin) — Superior fit — $15.99 at Amazon

## Where to buy

- Amazon.com: $60.00 (https://www.amazon.com/dp/B07GMS1L24?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Squalane, Glycerin, Caprylic Capric Triglyceride, Isoamyl Laurate, Butyrospermum Parkii Butter Shea Butter, Sorbitan Olivate, Cetearyl Olivate, Ceramide Np, Jojoba Esters, Sodium Hyaluronate, Euterpe Oleracea Sterols, Linoleic Acid, Oleic Acid, Linolenic Acid, Ethyl Linoleate, Tocopherol, Isoamyl Cocoate, Cetyl Palmitate, Sorbitan Palmitate, Cetearyl Alcohol, Ethylhexylglycerin, Carbomer, Sodium Hydroxide, Phenoxyethanol, Sodium Gluconate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/biossance/squalane-omega-repair-cream/for/acne-prone-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/biossance/squalane-omega-repair-cream/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/biossance/squalane-omega-repair-cream/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/biossance/squalane-omega-repair-cream/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/biossance/squalane-omega-repair-cream/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/biossance/squalane-omega-repair-cream/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/biossance/squalane-omega-repair-cream/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/biossance/squalane-omega-repair-cream/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/biossance/squalane-omega-repair-cream/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/biossance/squalane-omega-repair-cream/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/biossance/squalane-omega-repair-cream/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/biossance/squalane-omega-repair-cream/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/biossance/squalane-omega-repair-cream/for/acne-prone-skin