🇺🇸United States

Biossance Squalane + Omega Repair Cream for acne-prone skin

Biossance Squalane + Omega Repair Cream

Average

  • AverageCombination Skin Fit
  • AverageEffectiveness
  • ExcellentSafety

Works for acne-prone skin; other moisturizers fit it better.

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Offers moderate suitability for your combination skin, as squalane and glycerin provide emollient and humectant actions to hydrate and enhance barrier resilience without causing irritation. These ingredients are supportive for general skincare benefits but not specifically targeted for your acne, blemishes, and breakouts.
  • While the formula lacks sufficient ingredients for optimal oil control on your oily areas, the presence of ceramides and squalane ensures a good safety profile by soothing the skin.
  • The product is safe for your acne-prone skin due to the absence of harsh ingredients and the inclusion of soothing components.

How to apply

  • Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
  • Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
  • Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
  • Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
  • Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.

People Say

★4.3Overall rating based on 3.0k+ reviews

Many users love its luxurious, non-greasy texture and find it soothing for sensitive skin, also noting it works well as a makeup base. A significant portion of reviews consistently cite a distinct, unpleasant natural scent as a major drawback, despite the product's effective performance in plumping and smoothing skin texture. Some users also find the price point high and a minority with extremely dry skin felt it wasn't rich enough.

Highlights

  • Deep hydration Mostly Mentioned
    • “melts into my skin like butter”
    • “leaves skin feeling instantly hydrated and plump”
    • “my dry patches? gone.”
  • Unpleasant scent Mostly Mentioned
    • “smells like dirty feet”
    • “smells straight up fishy”
    • “weird fermented smell”
  • Non-greasy texture Often Mentioned
    • “rich but lightweight”
    • “absorbs fast, no residue”
    • “decadent whipped texture”
  • Excellent makeup base Sometimes Noted
    • “makeup sits better”
    • “great primer for dry skins”
    • “leaves a lit-from-within glow”
  • Soothing for sensitive Sometimes Noted
    • “only one that doesn't make my skin flare up”
    • “calm and clear”
  • High price point Sometimes Noted
    • “expensive for what it is”
    • “wish it were more concentrated for the cost”
    • “splurge product”
  • Not rich enough Rarely Noted
    • “have to use more product than expected”
    • “felt too lightweight”
    • “skin felt parched hours later”
  • Packaging issues Rarely Noted
    • “lid was busted”
    • “jar arrived open”
    • “broken glass”

Sources: lovi.care, sephora.com.au, biossance.com, reddit.com, womenshealthmag.com, organicbeautylover.com, and more

Questions and answers

How well does Biossance Squalane + Omega Repair Cream work for acne-prone skin?

Biossance Squalane + Omega Repair Cream works well for acne-prone skin by providing hydration and soothing the skin without causing irritation, though it lacks targeted ingredients for breakouts. To fit acne-prone skin better, a moisturizing treatment needs ingredients specifically targeted for acne and blemishes.

Clinical, Cosmetic and Investigational Dermatology, 2017

Which ingredients make this cream a good fit for acne-prone skin?

Squalane and ceramides make this cream a safe fit by soothing your skin and supporting its barrier without causing irritation. However, a product for acne-prone skin also needs ingredients that specifically target blemishes and breakouts while helping to control oil.

Molecules, 2025

What does Squalane do for acne-prone skin?

Squalane may help keep acne-prone skin soft and smooth, but peroxidated forms can trigger inflammation in skin cells. For a better fit on acne-prone skin, products need non-clogging, soothing ingredients that balance oil without causing irritation.

The Journal of Investigative Dermatology, 2006

What do Ceramides do for acne-prone skin?

Ceramides help acne-prone skin by restoring a weak water barrier, which is often damaged and low in these protective lipids in people with acne. Using them helps reduce dryness, redness, and irritation caused by acne treatments while keeping the skin calm and smooth.

Journal of Drugs in Dermatology, 2023Archives of Dermatological Research, 1995

Where does this cream go in a skincare routine for acne-prone skin?

This cream goes toward the end of your morning and evening routines as your moisturizer step, right after your hydrating toner and treatment. It keeps your skin soft and calm with a safe, gentle formula, though acne-prone skin needs a product that also provides targeted oil control and blemish-fighting ingredients.

Can I use this cream with retinol, and in what order?

You can use this cream with retinol by applying the retinol first, letting it dry, and then smoothing on your moisturizer to help calm the skin. Using a barrier-supporting moisturizer alongside retinol is unlikely to cause irritation and may make your routine more comfortable.

Cutis, 2006

How often should I use this cream?

You can use this moisturizing treatment twice daily to keep your skin soft and hydrated. Daily application helps improve moisture and protects the skin barrier without causing irritation.

Journal of Cosmetic Dermatology, 2020Health Science Reports, 2021

Can this cream clog pores, cause breakouts or purging for acne-prone skin?

This cream is unlikely to clog pores or cause breakouts on your acne-prone skin because it avoids harsh ingredients and includes soothing components. However, because it lacks targeted ingredients for oil control, acne-prone skin generally needs lightweight hydrators and oil-balancing ingredients like salicylic acid or niacinamide to help keep breakouts clear.

Can I use this cream around the eyes or on my body?

You can use this moisturizing treatment around the eyes and on the body because it is safe for the skin, but a product of this type needs lighter textures for very thin eye areas and richer hydration for dry body skin.

Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.

What the research says

  • A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

    Clinical, Cosmetic and Investigational Dermatology, 2017
  • Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts.

    Molecules, 2025
  • Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway.

    Antioxidants, 2025
  • Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

    Journal of Drugs in Dermatology, 2011
  • Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

    Clinical Oral Investigations, 2022
  • Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

    BMC Oral Health, 2019
  • A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events.

    Lasers in Medical Science, 2025
  • A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells.

    International Journal of Cosmetic Science, 2025

Why other moisturizers fit acne-prone skin better

Ingredients

Water, Squalane, Glycerin, Caprylic Capric Triglyceride, Isoamyl Laurate, Butyrospermum Parkii Butter Shea Butter, Sorbitan Olivate, Cetearyl Olivate, Ceramide Np, Jojoba Esters, Sodium Hyaluronate, Euterpe Oleracea Sterols, Linoleic Acid, Oleic Acid, Linolenic Acid, Ethyl Linoleate, Tocopherol, Isoamyl Cocoate, Cetyl Palmitate, Sorbitan Palmitate, Cetearyl Alcohol, Ethylhexylglycerin, Carbomer, Sodium Hydroxide, Phenoxyethanol, Sodium Gluconate

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

How does it fit your skin?

Scan your face, then any product: Lovi shows how well it fits you and what fits even better.