# Biologique Recherche Crème Dermopurifiante for sensitive skin

**Lovi Fit: Average fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/p/biologique-recherche/creme-dermopurifiante/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Biologique Recherche](https://lovi.care/skincare/brands/biologique-recherche)
Category: [Serums and treatments](https://lovi.care/skincare/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for sensitive skin; other serums fit it better.

## Why this fit

- Suitable for normal skin, this product contains niacinamide and glycerin to support barrier repair and hydration, but lacks specialized ingredients to directly address your redness and irritation concerns.
- While it offers general soothing benefits, the formulation does not prioritize ingredients that would effectively calm inflammation or reduce visible redness.
- The product is safe for your sensitive skin, as it avoids harsh ingredients and includes soothing components like Centella Asiatica Extract.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/biologique-recherche/creme-dermopurifiante/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/p/biologique-recherche/creme-dermopurifiante/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/p/biologique-recherche/creme-dermopurifiante/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/p/biologique-recherche/creme-dermopurifiante/for/sensitive-skin): Average (this page)
- [Acne-prone skin](https://lovi.care/skincare/p/biologique-recherche/creme-dermopurifiante/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/p/biologique-recherche/creme-dermopurifiante/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/p/biologique-recherche/creme-dermopurifiante/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/p/biologique-recherche/creme-dermopurifiante/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/p/biologique-recherche/creme-dermopurifiante/for/oily-acne-prone-skin): Average

## Key ingredients

Niacinamide, Mimosa Tenuiflora Extract, Centella Asiatica Extract, Arnica Montana Extract, Salicylic Acid

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Chitosan/Mimosa tenuiflora bio-composite films exhibited improved thermal stability, increased water-uptake ability, antibacterial properties against Escherichia Coli and Micrococcus, and were non-toxic in cytotoxicity assays. ([International Journal of Biological Macromolecules, 2016](https://pubmed.ncbi.nlm.nih.gov/27693339/))
- Arabinogalactan-enriched fractions isolated from Mimosa tenuiflora bark significantly stimulated mitochondrial activity and proliferation in human primary dermal fibroblasts while having minor influence on HaCaT keratinocytes. ([Journal of Ethnopharmacology, 2009](https://pubmed.ncbi.nlm.nih.gov/19505559/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Gels containing 1% Arnica montana L. flower extract successfully enhanced the volume of the lips and face with a reduction of wrinkles in humans. ([International Journal of Cosmetic Science, 2023](https://pubmed.ncbi.nlm.nih.gov/35984685/))
- Topical application of Arnica montana ointment reduced the inflammatory response and oxidative damage in mice exposed to UVB radiation compared to untreated UVB-exposed skin. ([Cutaneous and Ocular Toxicology, 2020](https://pubmed.ncbi.nlm.nih.gov/32183539/))
- The protocol combining microcurrent with topical Arnica montana reduces inflammation, increases myofibroblast proliferation, and decreases macrophage presence in rats with skin lesions compared to controls. ([International Journal of Experimental Pathology, 2023](https://pubmed.ncbi.nlm.nih.gov/36752313/))
- Cryotherapy with liquid nitrogen achieved a higher cure rate (39%) than salicylic acid (24%) and a wait-and-see approach (16%) for cutaneous warts at 13 weeks in primary care patients. ([CMAJ, 2010](https://pubmed.ncbi.nlm.nih.gov/20837684/))
- A moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid significantly reduced noninflammatory, inflammatory, and total acne lesion counts compared to a vehicle control in Thai patients during a 12-week maintenance phase. ([BioMed Research International, 2020](https://pubmed.ncbi.nlm.nih.gov/33150170/))
- Treatment with 2% supramolecular salicylic acid hydrogel resulted in a regression and markedly improvement rate of 51.01% compared to 43.10% for Adapaline gel in patients with mild to moderate facial acne vulgaris, showing no significant difference in efficacy. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590107/))

## Why other serums fit sensitive skin better

- Topical application of TAT-SOD significantly suppresses UVB-induced erythema formation, blood flow rise, and apoptotic sunburn cell formation in human volunteers compared to a vehicle control. ([European Journal of Pharmaceutics and Biopharmaceutics, 2016](https://pubmed.ncbi.nlm.nih.gov/27460952/))
- Topically applied Avena sativa and Avena Rhealba oatmeal extracts significantly reduced skin irritation parameters including a* parameter increase and blood flow increase compared to vehicle in 12 healthy individuals subjected to the sodium lauryl sulfate irritation model. ([Skin Pharmacology and Applied Skin Physiology, 2002](https://pubmed.ncbi.nlm.nih.gov/11867969/))

## What reviewers say

Users with oily, acne-prone, and congested skin frequently report that this cream effectively regulates sebum and clears breakouts without causing dryness. The distinct, often-mentioned yeasty scent is a common drawback, but the majority of users find the balancing, purifying, and redness-reducing benefits outweigh this sensory aspect.

- Liked: Clears acne (mostly mentioned)
- Disliked: Unpleasant scent (mostly mentioned)
- Liked: Balances oil production (often mentioned)
- Disliked: High price (often mentioned)
- Liked: Hydrates without greasiness (sometimes noted)
- Liked: Refines texture (sometimes noted)
- Liked: Soothes redness (sometimes noted)
- Disliked: Initial reaction (rarely noted)
- Disliked: Reformulation concerns (rarely noted)
- Disliked: Texture issues (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Biologique Recherche Crème Dermopurifiante work for sensitive skin?

This cream works for sensitive skin by using niacinamide and glycerin to support barrier repair and hydration, though it lacks specialized ingredients to directly target redness and irritation. While it is safe and includes soothing components like Centella Asiatica Extract, treatments that fit sensitive skin better need targeted ingredients that effectively calm inflammation and reduce visible redness.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Which ingredients make this cream a good fit for sensitive skin?

This cream works for your sensitive skin because it includes niacinamide and glycerin to support hydration and barrier repair, alongside soothing plant extracts like Centella Asiatica. However, this skin type needs a treatment with specialized ingredients that actively calm inflammation and target visible redness.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### What does Niacinamide do for sensitive skin?

Niacinamide helps calm sensitive skin by strengthening the skin barrier and reducing redness and irritation. It is very well tolerated and may improve overall comfort and resilience with regular use.
Sources: [Cutis, 2005](https://pubmed.ncbi.nlm.nih.gov/16209160/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### What does Mimosa Tenuiflora Extract do for sensitive skin?

Mimosa Tenuiflora Extract helps calm sensitive skin and supports its natural recovery process. It is unlikely to cause irritation and may soothe red or dry areas.

### Where does this cream go in a skincare routine for sensitive skin?

This treatment goes in the evening routine after cleansing and toning, and before moisturizing. A product of this type needs barrier-supporting ingredients like niacinamide and glycerin alongside soothing components like centella asiatica extract, but for sensitive skin it also needs targeted ingredients to calm inflammation and reduce visible redness.

### Can I use it with retinol, and in what order?

You can use this treatment alongside retinol by applying it after your retinol and before your moisturizer in your evening routine. This product is unlikely to irritate your skin, though a sensitive skin routine works best with calming ingredients that directly target redness and inflammation.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/)

### How often should I use this cream?

This treatment should be used once a week in the evening for your sensitive skin, and if you tolerate it well and see good results, you can carefully use it more often. While it has a safe profile and includes soothing Centella Asiatica Extract, this product needs extra anti-inflammatory ingredients and focused redness-calming components to be a great fit for sensitive skin.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Can it clog pores, cause breakouts or purging for sensitive skin?

This cream is unlikely to clog pores or cause breakouts on sensitive skin, as it avoids harsh ingredients and includes soothing components like Centella Asiatica Extract. Sensitive skin prone to breakouts instead needs targeted formulas rich in anti-inflammatory extracts and specialized ingredients that actively calm irritation and reduce redness.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for sensitive skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/sensitive-skin) — Superior fit — $53.00 at Amazon
- [Clarins Double Serum](https://lovi.care/skincare/p/clarins/double-serum/for/sensitive-skin) — High fit — $142.00 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/p/skinceuticals/c-e-ferulic/for/sensitive-skin) — High fit — $39.99 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — $28.08 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/p/clarins/soothing-toning-lotion/for/sensitive-skin) — Superior fit — $28.05 at Amazon
- Moisturizer with Sun Protection: [innisfree Daily Mild Sunscreen](https://lovi.care/skincare/p/innisfree/daily-mild-sunscreen/for/sensitive-skin) — Superior fit — $18.00 at Amazon

## Where to buy

- Amazon.com: $187.90 (https://www.amazon.com/dp/B0BMMBF9BX?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
Prices checked 5 Nov 2026.

## Ingredients

Water, Propylene Glycol, Glycerin, Dicaprylyl Carbonate, Butylene Glycol, Sucrose Polystearate, C10-18 Triglycerides, Cetyl Alcohol, 1,2-Hexanediol, Niacinamide, Polyamide-5, Arctium Lappa Root Extract, Betula Alba Bark Extract, Enantia Chlorantha Bark Extract Moambe Jaune Bark Extract, Equisetum Arvense Extract, Mimosa Tenuiflora Bark Extract Acacia Decurrens Bark Extract, Hedera Helix Stem Extract Leaf, Fucus Vesiculosus Extract, Centella Asiatica Extract, Spiraea Ulmaria Extract, Arnica Montana Flower Extract, Rosa Canina Fruit Extract, Achillea Millefolium Extract Common Yarrow Extract, Aesculus Hippocastanum Seed Extract, Lavandula Angustifolia Flower Extract Lavender Flower Extract, Thymus Vulgaris Extract, Myrtus Communis Extract, Onion Bulb Extract, Commiphora Myrrha Extract Resin, Oleanolic Acid, Glycine Soja Oil Soybean Oil, Yeast Extract, Citric Acid, Tocopherol, Sodium Stearoyl Glutamate, Hydrogenated Polyisobutene, Polyacrylate Crosspolymer-6, Caprylyl Glycol, Phenoxyethanol, Sodium Benzoate, Potassium Sorbate, Sorbic Acid
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/biologique-recherche/creme-dermopurifiante/for/sensitive-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/biologique-recherche/creme-dermopurifiante/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/biologique-recherche/creme-dermopurifiante/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/biologique-recherche/creme-dermopurifiante/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/biologique-recherche/creme-dermopurifiante/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/biologique-recherche/creme-dermopurifiante/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/biologique-recherche/creme-dermopurifiante/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/biologique-recherche/creme-dermopurifiante/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/biologique-recherche/creme-dermopurifiante/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/biologique-recherche/creme-dermopurifiante/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/biologique-recherche/creme-dermopurifiante/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/biologique-recherche/creme-dermopurifiante/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/biologique-recherche/creme-dermopurifiante/for/sensitive-skin