# Bioderma Sébium Lotion for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: Superior · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/p/bioderma/sebium-lotion/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Bioderma](https://lovi.care/skincare/brands/bioderma)
Category: [Toners](https://lovi.care/skincare/best/toners)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other toners fit it better.

## Why this fit

- Offers excellent hydration for your oily skin due to the presence of glycerin and xylitol, which provide moisturizing effects that balance your combination skin type.
- Provides moderate pore-refining benefits for oily shine with salicylic acid and seboregulation from zinc gluconate, which are suitable for your combination skin.
- The product is safe for your combination skin as it lacks prohibited or harsh ingredients, minimizing irritation risks.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/bioderma/sebium-lotion/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/p/bioderma/sebium-lotion/for/dry-skin): Caution
- [Combination skin](https://lovi.care/skincare/p/bioderma/sebium-lotion/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/p/bioderma/sebium-lotion/for/sensitive-skin): Low
- [Acne-prone skin](https://lovi.care/skincare/p/bioderma/sebium-lotion/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/p/bioderma/sebium-lotion/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/p/bioderma/sebium-lotion/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/p/bioderma/sebium-lotion/for/dry-sensitive-skin): Caution
- [Oily acne-prone skin](https://lovi.care/skincare/p/bioderma/sebium-lotion/for/oily-acne-prone-skin): Average

## Key ingredients

Salicylic Acid, Zinc Gluconate, Fomes Officinalis Extract Mushroom Extract, Capryloyl Glycine, Glycerin

## What the research says

- A formulation containing glycerol (5%) and xylitol (5%) applied twice daily for 14 days increased skin hydration, filaggrin protein quantity, interdigitation index, and biomechanical properties, and decreased transepidermal water loss compared to untreated and vehicle-treated skin in twelve volunteers with dry skin. ([Acta Dermato-venereologica, 2017](https://pubmed.ncbi.nlm.nih.gov/27349297/))
- A mixture of propanediol, xylitol, and caprylic acid demonstrated in vitro antimicrobial activity against C. acnes and S. aureus, reduced 5-alpha reductase expression, and decreased skin oiliness, porphyrin, and inflammatory lesions in participants over 28 days. ([Molecules, 2021](https://pubmed.ncbi.nlm.nih.gov/34771112/))
- Daily use of a deep cleansing gel containing salicylic acid 2%, zinc gluconate 0.2% and lipohydroxy acid 0.05% significantly reduced total lesion count by 56.3% after 84 days in 35 subjects with mild to moderate truncal acne. ([Clinical, Cosmetic and Investigational Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36698447/))
- A dermocosmetic cream containing Punica granatum Pericarp extract, Salicylic acid, Niacinamide, Zinc gluconate, and Aqua Posae Filiformis significantly decreased inflammatory, non-inflammatory, and total lesion counts in subjects with mild to moderate acne compared to untreated hemi-faces after 15 days. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41487026/))
- Cryotherapy with liquid nitrogen achieved a higher cure rate (39%) than salicylic acid (24%) and a wait-and-see approach (16%) for cutaneous warts at 13 weeks in primary care patients. ([CMAJ, 2010](https://pubmed.ncbi.nlm.nih.gov/20837684/))
- A moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid significantly reduced noninflammatory, inflammatory, and total acne lesion counts compared to a vehicle control in Thai patients during a 12-week maintenance phase. ([BioMed Research International, 2020](https://pubmed.ncbi.nlm.nih.gov/33150170/))
- Treatment with 2% supramolecular salicylic acid hydrogel resulted in a regression and markedly improvement rate of 51.01% compared to 43.10% for Adapaline gel in patients with mild to moderate facial acne vulgaris, showing no significant difference in efficacy. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590107/))
- Different strains of Propionibacterium acnes modulate cutaneous innate immunity with varying pro-inflammatory potentials, with P. acnes type III showing the highest and P. avidum the weakest, and zinc gluconate down-regulates the expression of most induced immune markers. ([Experimental Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23947673/))
- Zinc gluconate induced alpha2, alpha3, alphaV, and alpha6 integrins, copper gluconate induced alpha2, alpha6, and beta1, and manganese gluconate induced most studied integrins in cultured keratinocytes. ([The British Journal of Dermatology, 1999](https://pubmed.ncbi.nlm.nih.gov/10215764/))
- White button mushroom extract treatment increased VEGF densities, EGF, PCNA, and collagen fibers, while decreasing apoptotic cells and limiting TGF-beta and CD4 reactions in ICR mice and chorioallantoic culture, indicating beneficial effects on skin regeneration and injury. ([Microscopy Research and Technique, 2012](https://pubmed.ncbi.nlm.nih.gov/22581761/))
- Topical application of a formulation containing capryloyl glycine 4% significantly decreased hair density, median hair length, and terminal hair density on the forearms compared to placebo in female patients with hypertrichosis after 120 days. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33347705/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))

## What reviewers say

Users with combination to oily skin frequently praise this lotion for its effectiveness in regulating sebum and reducing shine, while also providing lightweight hydration. Many reviewers report a visible reduction in breakouts and refined pore texture, noting it as a beneficial prep step for balanced skin. A moderate number of users find the fragrance to be strong or artificial, and a low number report a sticky residue or minor irritation.

- Liked: Effective oil control (mostly mentioned)
- Liked: Lightweight hydration (often mentioned)
- Liked: Reduces breakouts (sometimes noted)
- Liked: Refines pores (sometimes noted)
- Disliked: Strong fragrance (sometimes noted)
- Disliked: Eye/skin irritation (rarely noted)
- Disliked: Price point (rarely noted)
- Disliked: Sticky residue (rarely noted)

## How to apply

- Use this hydrating toner in your AM and PM routines. Start 3 times a week and move to daily use if your skin likes it.
- Apply this hydrating toner after your cleanser and before your moisturizer or SPF. This keeps your skin balanced and ready.
- Gently press 2-3 drops of the hydrating toner into your skin with your hands. Let it ⏳absorb for a minute before the next step.
- Apply the hydrating toner on slightly damp skin to help it absorb better. Clean skin gives the best results for your oily shine goal.
- Avoid the eye area when using your hydrating toner. Always do a quick patch test before your first use.
- Video: https://storage.pora.ai/25abe7eb181ba53153fd15de2058c2a9.mp4

## Questions and answers

### How well does Bioderma Sébium Lotion work for combination skin?

Bioderma Sébium Lotion works moderately well for combination skin, offering balanced hydration and managing oily shine safely without irritation. However, a product of this type needs an optimal blend of soothing ingredients and lightweight hydrators that specifically cater to combination skin without overwhelming oilier areas.
Sources: [Acta Dermato-venereologica, 2017](https://pubmed.ncbi.nlm.nih.gov/27349297/), [Molecules, 2021](https://pubmed.ncbi.nlm.nih.gov/34771112/)

### Which ingredients make this toner a good fit for combination skin?

Glycerin and xylitol help balance your combination skin by providing moisture, while salicylic acid and zinc gluconate help manage oily shine. A toner for this skin type needs an optimal blend of soothing plant extracts and lightweight hydrators that manage oil without causing irritation.
Sources: [Acta Dermato-venereologica, 2017](https://pubmed.ncbi.nlm.nih.gov/27349297/), [Molecules, 2021](https://pubmed.ncbi.nlm.nih.gov/34771112/)

### What does Salicylic Acid do for combination skin?

Salicylic acid helps clear clogged pores and balance oily areas while remaining gentle enough for dry spots on combination skin. It reduces breakouts and oiliness effectively with a low likelihood of irritation.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/), [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/38051857/)

### What does Zinc Gluconate do for combination skin?

Zinc Gluconate is a good fit for combination skin because it helps calm redness and manage breakouts while supporting skin health. This type of skin needs gentle oil-balancing ingredients and soothing elements to keep areas clear and comfortable.
Sources: [Dermatologic Therapy, 2018](https://pubmed.ncbi.nlm.nih.gov/29193602/), [Dermatology, 2001](https://pubmed.ncbi.nlm.nih.gov/11586012/)

### Where does it go in a skincare routine for combination skin?

Bioderma Sébium Lotion goes in your morning routine right after cleansing and before your moisturizer. It works well for combination skin by keeping oily shine under control with salicylic acid and zinc gluconate, while glycerin and xylitol provide reliable moisture. To get an even better fit for this skin type, a product of this type needs extra soothing and strengthening ingredients that deeply balance dry and oily areas.
Sources: [Acta Dermato-venereologica, 2017](https://pubmed.ncbi.nlm.nih.gov/27349297/), [Clinical, Cosmetic and Investigational Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36698447/)

### Can I use this toner with retinol, and in what order?

You can use this toner with retinol by applying the toner first after cleansing to hydrate your skin, and following it with your retinol treatment. This product of this type needs soothing and hydrating ingredients like ceramides and hyaluronic acid to better support a combination skin barrier alongside retinol.
Sources: [Acta Dermato-venereologica, 2017](https://pubmed.ncbi.nlm.nih.gov/27349297/)

### How often should I use it?

You can use this hydrating toner daily in your morning routine after cleansing, as it has a safe formula that is unlikely to cause irritation. Ingredients like glycerin and xylitol help keep your combination skin soft and balanced by boosting hydration. To better fit combination skin, products of this type also need ingredients that provide oil control and pore-refining benefits.
Sources: [Acta Dermato-venereologica, 2017](https://pubmed.ncbi.nlm.nih.gov/27349297/)

### Can this toner clog pores, cause breakouts or purging for combination skin?

This toner is unlikely to clog pores or cause breakouts for combination skin because it features ingredients that clear pores and keep oil in check safely. To get a better fit for combination skin, a product of this type needs extra pore-clearing ingredients and deep hydrators that balance oily and dry areas without leaving a sticky feel.
Sources: [Acta Dermato-venereologica, 2017](https://pubmed.ncbi.nlm.nih.gov/27349297/), [Clinical, Cosmetic and Investigational Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36698447/)

### Is it fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum).

## Alternatives for combination skin

- [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/p/some-by-mi/snail-truecica-miracle-repair-toner/for/combination-skin) — Superior fit — $15.60 at Amazon
- [Dear, Klairs Supple Preparation Facial Toner](https://lovi.care/skincare/p/dear-klairs/supple-preparation-facial-toner/for/combination-skin) — Superior fit — $16.60 at Amazon
- [Mizon Snail Repair Intensive Toner](https://lovi.care/skincare/p/mizon/snail-repair-intensive-toner/for/combination-skin) — Superior fit — $21.50 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — $28.08 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — $18.99 at Amazon
- SPF: [CeraVe AM Facial Moisturizing Lotion](https://lovi.care/skincare/p/cerave/am-facial-moisturizing-lotion-spf-30/for/combination-skin) — Superior fit — $14.97 at Amazon

## Where to buy

No store in United States has a checked price for this product, so the page shows none.

## Ingredients

Water, Peg-11 Methyl Ether Dimethicone, Butylene Glycol, Glycerin, Fomes Officinalis Extract Mushroom Extract, Capryloyl Glycine, Polysorbate 20, Sodium Citrate, Zinc Gluconate, Salicylic Acid, Sodium Hydroxide, Mannitol, Sodium Metabisulfite, Xylitol, Rhamnose, Pyridoxine Hcl, Propyl Gallate, Peg-40 Hydrogenated Castor Oil, Fructooligosaccharides, Phenoxyethanol, Parfum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/bioderma/sebium-lotion/for/combination-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/bioderma/sebium-lotion/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/bioderma/sebium-lotion/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/bioderma/sebium-lotion/for/combination-skin
- France: https://lovi.care/skincare/fr/p/bioderma/sebium-lotion/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/bioderma/sebium-lotion/for/combination-skin
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- Canada: https://lovi.care/skincare/ca/p/bioderma/sebium-lotion/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/bioderma/sebium-lotion/for/combination-skin
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- United Arab Emirates: https://lovi.care/skincare/ae/p/bioderma/sebium-lotion/for/combination-skin