# Azclear Medicated Lotion for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/p/azclear/medicated-lotion/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Azclear](https://lovi.care/skincare/brands/azclear)
Category: [Serums and treatments](https://lovi.care/skincare/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other serums fit it better.

## Why this fit

- Offers moderate treatment for your acne-prone combination skin, as azelaic acid helps reduce acne lesions and blemishes while glycerin provides hydration.
- Aluminum and magnesium silicate offer mattifying effects that can help with oily shine, though stronger mattifying agents might be more effective for your primary concern.
- The product is safe for your combination skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/azclear/medicated-lotion/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/p/azclear/medicated-lotion/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/p/azclear/medicated-lotion/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/p/azclear/medicated-lotion/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/p/azclear/medicated-lotion/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/p/azclear/medicated-lotion/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/p/azclear/medicated-lotion/for/mature-skin): Low
- [Dry sensitive skin](https://lovi.care/skincare/p/azclear/medicated-lotion/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/p/azclear/medicated-lotion/for/oily-acne-prone-skin): High

## Key ingredients

Azelaic Acid W W, Glycerin, Phenoxyethanol, Xanthan Gum

## What the research says

- Azelaic acid nanocrystal hydrogel 10% achieved a higher success rate and greater lesion reduction than azelaic acid cream 20% in patients with mild to moderate facial acne. ([Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/))
- Application of 15% azelaic acid gel significantly reduced post-inflammatory erythema and hyperpigmentation, decreased hemoglobin and melanin content, improved quality of life, and contributed to acne improvement in patients with mild to moderate acne compared to placebo. ([Dermatology and Therapy, 2024](https://pubmed.ncbi.nlm.nih.gov/38734843/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical application of a dermocosmetic containing Myrtus communis extract and azelaic acid reduced acne relapses and helped maintain remission compared to a light moisturizing cream in adult females in the acne maintenance phase over 16 weeks. ([Journal of the European Academy of Dermatology and Venereology, 2023](https://pubmed.ncbi.nlm.nih.gov/36729399/))
- Topical administration of 20% azelaic acid cream and 5% tranexamic acid solution comparably improved acne-related postinflammatory hyperpigmentation in patients with acne vulgaris, while tranexamic acid demonstrated a significantly better safety profile at week 4. ([Journal of Research in Medical Sciences, 2023](https://pubmed.ncbi.nlm.nih.gov/37213446/))
- Azelaic acid 15% gel showed comparable efficacy to adapalene 0.1% gel in reducing lesions, severity, and Dermatology Life Quality Index in women with adult acne, with significantly lower dryness and scaling, and demonstrated superiority during maintenance compared to no further treatment. ([Journal of the European Academy of Dermatology and Venereology, 2015](https://pubmed.ncbi.nlm.nih.gov/25399481/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Biodegradable wound dressings functionalized with silver nanoparticles showed >99% pathogen growth inhibition, bactericidal effects, free radical scavenging, reduced inflammatory response in macrophages, and accelerated wound healing in animals. ([International Journal of Biological Macromolecules, 2022](https://pubmed.ncbi.nlm.nih.gov/35780920/))
- A topical xanthan gum nanogel containing gamma-oryzanol-loaded nanostructured lipid carriers and nanosized TiO2 and MBBT filters demonstrated high photoprotection with an SPF of 34 and no skin irritation or sensitization in a rat model. ([Pharmaceuticals, 2023](https://pubmed.ncbi.nlm.nih.gov/37242453/))
- Dense chitosan-xanthan membranes associated with multipotent mesenchymal stromal cells accelerated wound healing in Wistar rats compared to untreated conditions, demonstrating safety and feasibility for dermo-epidermal wound treatment. ([Journal of Biomaterials Applications, 2015](https://pubmed.ncbi.nlm.nih.gov/25281644/))

## Why other serums fit combination skin better

- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))
- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))

## What reviewers say

A common drawback is the product's tendency to pill or ball up when layered with other products.

- Liked: Effective acne treatment (mostly mentioned)
- Disliked: Pilling and texture (mostly mentioned)
- Liked: Reduces redness (often mentioned)
- Liked: Affordable value (sometimes noted)
- Liked: Gentle and non-drying (sometimes noted)
- Disliked: Stinging sensation (sometimes noted)
- Disliked: Slow absorption (rarely noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Azclear Medicated Lotion work for combination skin?

Azclear Medicated Lotion works moderately well for combination skin by helping clear acne spots with azelaic acid, hydrating with glycerin, and reducing oily shine with aluminum and magnesium silicate. It is safe for this skin type, but this skin needs ingredients like niacinamide, zinc PCA, and propolis to balance moisture and regulate oiliness more effectively.
Sources: [Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this lotion a good fit for combination skin?

Azelaic acid helps reduce blemishes and glycerin provides hydration for your combination skin. A treatment for combination skin needs effective ingredients like niacinamide, propolis, and zinc PCA to enhance radiance and regulate oiliness without irritation.
Sources: [Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/), [Dermatology and Therapy, 2024](https://pubmed.ncbi.nlm.nih.gov/38734843/)

### What does Azelaic Acid do for combination skin?

Azelaic acid helps calm angry, red spots and smooth out rough or uneven patches on combination skin. It also helps clear pores and keeps skin looking even without causing extra dryness.
Sources: [Postepy Dermatologii I Alergologii, 2023](https://pubmed.ncbi.nlm.nih.gov/38282869/), [Journal of Drugs in Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/26355614/)

### What does Glycerin do for combination skin?

Glycerin helps keep combination skin soft and smooth by pulling moisture in and keeping it there. It improves hydration and supports your skin barrier, which is unlikely to cause irritation.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Where does this lotion go in a skincare routine for combination skin?

This treatment goes in your evening routine, applied after cleansing and before moisturizing. It is safe for your combination skin and helps reduce blemishes, though combination skin also needs stronger mattifying agents to fully control oily shine.

### Can I use it with retinol, and in what order?

You can use this treatment alongside retinol by applying the retinol first at night and following with this lotion, though your combination skin needs a product with stronger mattifying ingredients to best handle oily shine.

### How often should I use this lotion?

Use this lotion in the evening routine. A product of this type needs stronger mattifying agents to best care for combination skin.

### Can it clog pores, cause breakouts or purging for combination skin?

This treatment is unlikely to clog pores or cause breakouts on your combination skin because it contains acne-fighting azelaic acid and hydrating glycerin. It is safe for your skin type with no risk of irritation from harsh ingredients, though a product for this skin needs stronger mattifying agents to better handle oily shine.
Sources: [Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this lotion fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/combination-skin) — Superior fit — $16.75 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin) — Superior fit — $28.88 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/p/augustinus-bader/the-serum/for/combination-skin) — Superior fit — $200.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — $28.08 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — $25.60 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — $18.99 at Amazon

## Where to buy

No store in United States has a checked price for this product, so the page shows none.

## Ingredients

Azelaic Acid, Aluminum, Magnesium Silicate, Colloidal Silicon Dioxide, Glycerin, Phenoxyethanol, Water, Xanthan Gum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/azclear/medicated-lotion/for/combination-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/azclear/medicated-lotion/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/azclear/medicated-lotion/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/azclear/medicated-lotion/for/combination-skin
- France: https://lovi.care/skincare/fr/p/azclear/medicated-lotion/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/azclear/medicated-lotion/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/azclear/medicated-lotion/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/azclear/medicated-lotion/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/azclear/medicated-lotion/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/azclear/medicated-lotion/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/azclear/medicated-lotion/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/azclear/medicated-lotion/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/azclear/medicated-lotion/for/combination-skin