# AXIS-Y Dark Spot Correcting Glow Serum for skin with dark spots

**Lovi Fit: High fit for skin with dark spots.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/p/axis-y/dark-spot-correcting-glow-serum/for/dark-spots

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [AXIS-Y](https://lovi.care/skincare/brands/axis-y)
Category: [Serums and treatments](https://lovi.care/skincare/best/serums)

This fit is calculated for the concerns frequently associated with dark spots: hyperpigmentation, sun spots, and uneven skin tone. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for skin with dark spots; a few serums fit it even better.

## Why this fit

- Highly suitable for your normal skin, this serum effectively addresses pigmentation concerns with niacinamide and glutathione, which work to visibly reduce dark spots and even skin tone.
- The inclusion of sodium hyaluronate and rice bran extract further supports skin hydration and barrier function, complementing the brightening effects for overall skin health.
- The product is safe for your skin, featuring soothing ingredients like Calendula Officinalis Flower Extract and Allantoin, and contains no harsh or prohibited substances.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/axis-y/dark-spot-correcting-glow-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/p/axis-y/dark-spot-correcting-glow-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/p/axis-y/dark-spot-correcting-glow-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/p/axis-y/dark-spot-correcting-glow-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/p/axis-y/dark-spot-correcting-glow-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/p/axis-y/dark-spot-correcting-glow-serum/for/dark-spots): High (this page)
- [Mature skin](https://lovi.care/skincare/p/axis-y/dark-spot-correcting-glow-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/p/axis-y/dark-spot-correcting-glow-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/p/axis-y/dark-spot-correcting-glow-serum/for/oily-acne-prone-skin): High

## Key ingredients

Niacinamide, Squalane, Hippophae Rhamnoides Fruit Extract, Glutathione, Rice Bran Extract

## What the research says

- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- Topical oxidized glutathione significantly decreases the skin melanin index and improves moisture content, smoothness, wrinkle formation, and elasticity compared to placebo in healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/25378941/))
- Topical treatment of nicotinamide, alone or in combination with other active ingredients, reduces the progression of skin aging and hyperpigmentation in clinical trials while being well tolerated. ([Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/))
- Optimized transfersomes loaded with epigallocatechin-3-gallate and hyaluronic acid increased cell viability while reducing lipid peroxidation, intracellular ROS, and MMP expression in HaCaT cells, and exhibited higher skin permeation and deposition compared to plain EGCG. ([Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- Topical application of a sea buckthorn fruit extract formulation significantly reduced skin sebum secretion in 10 healthy human volunteers compared to the control base over an 8-week period. ([Journal of Pharmacy & Bioallied Sciences, 2010](https://pubmed.ncbi.nlm.nih.gov/21814424/))
- Topical emulsions containing Hippophae rhamnoides and Cassia fistula plant extracts significantly reduced skin sebum contents compared to placebo in patients with grade I and grade II acne vulgaris. ([Postepy Dermatologii I Alergologii, 2014](https://pubmed.ncbi.nlm.nih.gov/25254008/))
- Topical application of a 5% Hippophae rhamnoides oil-in-water emulsion significantly improved skin hydration (p=0.0003) and transepidermal water loss (p=0.0087) compared to a placebo base formulation in 13 healthy male subjects over 84 days. ([Pakistan Journal of Pharmaceutical Sciences, 2014](https://pubmed.ncbi.nlm.nih.gov/25362595/))
- Glutathione amino acid precursors effectively increase cellular glutathione levels, reducing oxidative stress, ATP depletion, and DNA damage in human keratinocytes, clinical subjects, and ex vivo skin compared to controls. ([Journal of the European Academy of Dermatology and Venereology, 2024](https://pubmed.ncbi.nlm.nih.gov/38189670/))
- Topical glutathione improves hyperpigmentation, reduces ultraviolet-induced erythema and wrinkles, decreases transepidermal water loss, and enhances antioxidant capacity. ([The Journal of Clinical and Aesthetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41416233/))
- RayGel reduced skin reaction severity with a lower average score of 93.7 compared to 123.3 for the placebo group in patients undergoing whole breast external-beam irradiation. ([American Journal of Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/15862509/))
- Topical gel and cream formulations containing niosomes entrapped with rice bran bioactive compounds improved skin hydration, lightening, thickness, roughness, and elasticity in 30 human volunteers over 28 days compared to baseline. ([Pharmaceutical Biology, 2012](https://pubmed.ncbi.nlm.nih.gov/22235888/))
- Gel and cream formulations containing rice bran bioactive compounds entrapped in niosomes increased in vitro antioxidant activity (ORAC values of 20-28 micromol TE/g versus 16-18 micromol TE/g for placebo), enhanced lipid peroxidation inhibition in human sebum by about 1.5 times, and improved in vivo human skin hydration by approximately 3 to 30% depending on the measurement technique. ([Journal of Nanoscience and Nanotechnology, 2011](https://pubmed.ncbi.nlm.nih.gov/21449379/))
- Stirring Nukadoko fermented rice bran beds by hand leads to temporary settlement of microorganisms on human skin with quick shedding. ([FEMS Microbiology Letters, 2023](https://pubmed.ncbi.nlm.nih.gov/37960971/))

## What reviewers say

Based on a very large amount of data, this lightweight serum is highly recommended for acne-prone and sensitive skin, effectively calming redness and gradually fading post-acne marks without causing irritation. It also hydrates and brightens the complexion. Users should note that consistent, long-term application is necessary to see significant results on dark spots, and it may not be potent enough for older or deeper hyperpigmentation.

- Liked: Lightweight texture (mostly mentioned)
- Liked: Fades acne marks (often mentioned)
- Liked: Gentle on sensitive skin (often mentioned)
- Disliked: Slow results (often mentioned)
- Liked: Brightens complexion (sometimes noted)
- Liked: Layers well (sometimes noted)
- Disliked: Ineffective for old scars (sometimes noted)
- Disliked: Breakouts (rare) (rarely noted)
- Disliked: Herbal scent (rarely noted)
- Disliked: Packaging issues (rarely noted)

## How to apply

- Apply this serum as part of your PM routine starting 3x/week and build up to daily use if your skin likes it.
- Place the serum after cleansing and toning, but before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute for it to absorb.
- Apply the serum on dry skin to help fade pigmentation effectively.
- Avoid the eye area and always use SPF 30+ during the day.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes AXIS-Y Dark Spot Correcting Glow Serum a great fit for skin with dark spots?

This serum is a great fit because it uses niacinamide and glutathione to visibly fade dark spots and even out your skin tone. It also includes soothing and hydrating ingredients like calendula, squalane, and rice bran extract to keep your skin calm and moisturized while brightening.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Clinical, Cosmetic and Investigational Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/25378941/)

### Which ingredients make this serum a good fit for skin with dark spots?

Niacinamide and glutathione make this serum a great fit because they help fade dark spots and even out your skin tone. Sodium hyaluronate and rice bran extract also support hydration, while calendula and allantoin help keep your skin calm.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Clinical, Cosmetic and Investigational Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/25378941/)

### What does Niacinamide do for skin with dark spots?

Niacinamide helps fade dark spots and uneven pigmentation by slowing down the transfer of pigment in the skin. It is generally well tolerated and may improve overall skin brightness with consistent use.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### What does Squalane do for skin with dark spots?

Squalane helps keep skin soft and smooth, but it is unlikely to directly fade dark spots on its own. For hyperpigmentation, this type of product needs added brightening ingredients like vitamin C or antioxidants to help even out skin tone.

### Where does this serum go in a skincare routine for skin with dark spots?

This serum goes in your evening routine, applied after cleansing and before moisturizing. Putting this type of treatment in the evening keeps things simple and provides extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

Yes, you can use this serum with retinol by applying your retinol first and following with this treatment serum, or by using retinol at night and this serum in the morning. This combination is generally well tolerated, though starting slowly helps ensure your skin stays calm and smooth as it adjusts to both active ingredients.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Clinical, Cosmetic and Investigational Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/25378941/)

### How often should I use this serum?

This serum is used in the evening routine for simplicity and extra safety around sun exposure, though some treatments can also be used in the morning or twice a day. Niacinamide and glutathione help reduce dark spots and even skin tone with regular daily use.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Clinical, Cosmetic and Investigational Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/25378941/)

### Can this serum clog pores, cause breakouts or purging for skin with dark spots?

This serum is unlikely to clog pores or cause breakouts, as it features a safe and gentle formula designed for daily use. While reactions are rare, any new treatment carries a slight chance of skin adjustment, but this product avoids harsh substances that typically trigger irritation.
Sources: [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for skin with dark spots

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/dark-spots) — Superior fit — $53.00 at Amazon
- [AMOREPACIFIC Time Response Skin Reserve Serum](https://lovi.care/skincare/p/amorepacific/time-response-skin-reserve-serum/for/dark-spots) — Superior fit — $525.00 at Amazon
- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/dark-spots) — High fit — $16.75 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/p/cerave/foaming-facial-cleanser/for/dark-spots) — Superior fit — $15.97 at Amazon
- Hydrating Toner: [Pyunkang Yul Calming Deep Moisture Toner](https://lovi.care/skincare/p/pyunkang-yul/calming-deep-moisture-toner/for/dark-spots) — Superior fit — $16.99 at Amazon
- Moisturizer: [Isntree Green Tea Fresh Serum](https://lovi.care/skincare/p/isntree/green-tea-fresh-serum/for/dark-spots) — Superior fit — $17.90 at Amazon

## Where to buy

- Amazon.com: $14.55 (https://www.amazon.com/dp/B091238V7N?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Glycerin, Niacinamide, Sodium Hyaluronate, Propanediol, Erythritol, Butylene Glycol, Squalane, Rice Bran Extract, Calendula Officinalis Flower Extract, Carica Papaya Fruit Extract, Hippophae Rhamnoides Fruit Extract, Acerola Fruit Extract, Polyglyceryl-10 Laurate, Chlorphenesin, Arginine, Ethylhexylglycerin, Carbomer, Glutathione, 1,2-Hexanediol, Hydroxypropyl Cyclodextrin, Disodium Edta, Hydroxyethylcellulose, Allantoin, Rosmarinus Officinalis Oil Leaf Rosemary Oil Leaf
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/axis-y/dark-spot-correcting-glow-serum/for/dark-spots (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/axis-y/dark-spot-correcting-glow-serum/for/dark-spots
- Ireland: https://lovi.care/skincare/ie/p/axis-y/dark-spot-correcting-glow-serum/for/dark-spots
- Germany: https://lovi.care/skincare/de/p/axis-y/dark-spot-correcting-glow-serum/for/dark-spots
- France: https://lovi.care/skincare/fr/p/axis-y/dark-spot-correcting-glow-serum/for/dark-spots
- Italy: https://lovi.care/skincare/it/p/axis-y/dark-spot-correcting-glow-serum/for/dark-spots
- Netherlands: https://lovi.care/skincare/nl/p/axis-y/dark-spot-correcting-glow-serum/for/dark-spots
- Spain: https://lovi.care/skincare/es/p/axis-y/dark-spot-correcting-glow-serum/for/dark-spots
- Canada: https://lovi.care/skincare/ca/p/axis-y/dark-spot-correcting-glow-serum/for/dark-spots
- Australia: https://lovi.care/skincare/au/p/axis-y/dark-spot-correcting-glow-serum/for/dark-spots
- Singapore: https://lovi.care/skincare/sg/p/axis-y/dark-spot-correcting-glow-serum/for/dark-spots
- Saudi Arabia: https://lovi.care/skincare/sa/p/axis-y/dark-spot-correcting-glow-serum/for/dark-spots
- United Arab Emirates: https://lovi.care/skincare/ae/p/axis-y/dark-spot-correcting-glow-serum/for/dark-spots