# Anua Niacinamide 10% + TXA 4% Dark Spot Correcting Serum for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Anua](https://lovi.care/skincare/brands/anua)
Category: [Serums and treatments](https://lovi.care/skincare/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other serums fit it better.

## Why this fit

- This serum offers moderate suitability for your combination skin, with niacinamide and tranexamic acid effectively addressing dark spots and providing some oil control. Glycerin and sodium hyaluronate offer general hydration, supporting your combination skin without specifically targeting oily shine.
- The inclusion of Centella Asiatica Extract and Panthenol ensures a soothing experience, minimizing irritation potential for your combination skin.
- The product is safe for your skin, containing no harsh ingredients and featuring beneficial soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/oily-acne-prone-skin): High

## Key ingredients

Niacinamide, Tranexamic Acid, Arbutin, Sodium Hyaluronate, Centella Asiatica Extract

## What the research says

- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- A non-hydroquinone topical formulation (SKNB19) improved hyperpigmentation by 28.5% in patient self-assessment and 27% in independent reviewer assessment compared with 4% hydroquinone in 18 adult subjects, while showing significantly less irritation and better tolerability. ([Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/33022197/))
- Encapsulation of alpha arbutin in an optimized ethosomal gel significantly improved skin melanin reduction, moisture content, and elasticity in human volunteers compared to conventional formulations. ([Heliyon, 2023](https://pubmed.ncbi.nlm.nih.gov/37681127/))
- Combining a home-based radiofrequency device and arbutin cream reduced mMASI scores by 25.6% and melanin index by 22.8% at 8 weeks compared to baseline in 38 participants. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/39918262/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))

## Why other serums fit combination skin better

- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))

## What reviewers say

Based on a very large amount of data, users consistently praise this serum for its ability to fade stubborn hyperpigmentation and post-acne marks while delivering a radiant glow. A notable minority experiences a sticky residue or skin irritation due to the high concentration of active ingredients.

- Liked: Fades dark spots (mostly mentioned)
- Liked: Brightens complexion (often mentioned)
- Liked: Lightweight texture (often mentioned)
- Disliked: Sticky residue (often mentioned)
- Liked: Hydrating finish (sometimes noted)
- Disliked: Causes breakouts (sometimes noted)
- Disliked: Skin irritation (rarely noted)
- Disliked: Slow results (rarely noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Anua Dark Spot Correcting Serum work for combination skin?

This serum works moderately well for your combination skin, using niacinamide and tranexamic acid to help fade dark spots and control oil while keeping skin calm. It also includes glycerin and sodium hyaluronate to provide general hydration, though a treatment for combination skin needs ingredients like zinc PCA or propolis to better manage oily shine while balancing dry areas.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for combination skin?

Niacinamide and tranexamic acid help fade dark spots while offering some oil control, and glycerin along with sodium hyaluronate provides balanced hydration. Centella asiatica extract and panthenol further soothe the skin to keep irritation low. To best support combination skin, this type of product needs ingredients like propolis or zinc PCA that regulate oiliness and maintain hydration without causing excess shine.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### What does Niacinamide do for combination skin?

Niacinamide helps balance oily areas by reducing excess shine and pore size while keeping dry patches hydrated and smooth. It also works to calm redness and even out skin tone, making it very suitable for combination skin.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### What does Tranexamic Acid do for combination skin?

Tranexamic acid helps fade dark spots and uneven areas across different parts of combination skin while improving overall brightness. This ingredient is generally well-tolerated and may help target unwanted pigment without causing widespread irritation.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38549196/), [Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/33022197/)

### Where does this serum go in a skincare routine for combination skin?

This treatment serum goes in the evening routine after your cleansing toner and before your moisturizer. Combination skin needs products with targeted active ingredients to fade dark spots and lightweight hydrators that balance oily shine without feeling heavy.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying this treatment first and following with your retinol once your skin is used to both. Combining active ingredients may sometimes cause irritation, so introducing them slowly helps your skin adjust safely.

### How often should I use this serum?

You can use this serum in the evening. Combination skin needs targeted oil control and lightweight hydration that balances dry and oily areas without clogging pores.

### Can this serum clog pores, cause breakouts or purging for combination skin?

This serum may occasionally cause breakouts for combination skin, as some reviewers have experienced, though irritation is unlikely. Combination skin usually needs lightweight hydration, targeted oil control, and non-pore-clogging soothing ingredients to keep the face clear and balanced.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/combination-skin) — Superior fit — $16.75 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin) — Superior fit — $28.88 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/p/augustinus-bader/the-serum/for/combination-skin) — Superior fit — $200.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — $28.08 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — $25.60 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — $18.99 at Amazon

## Where to buy

- Amazon.com: $21.85 (https://www.amazon.com/dp/B0CLLV2T1P?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Glycerin, Niacinamide, Tranexamic Acid, Butylene Glycol, Diethoxyethyl Succinate, 1,2-Hexanediol, Arbutin, Sodium Hyaluronate, Alpha-Arbutin, Coccinia Indica Fruit Extract, Eclipta Prostrata Extract, Macadamia Ternifolia Seed Oil, Olea Europaea Oil Fruit Olive Oil Fruit, Jojoba Seed Oil, Vitis Vinifera Seed Oil Grape Seed Oil, Theobroma Cacao Extract, Hydrolyzed Hyaluronic Acid, Chamaecyparis Obtusa Leaf Extract, Prunus Persica Flower Extract, Camellia Sinensis Seed Oil, Yeast Extract Ferment, Centella Asiatica Extract, Artemisia Princeps Leaf Extract, Candida Bombicola Glucose Methyl Rapeseedate Ferment, Pentylene Glycol, Betaine Salicylate, Sucrose Palmitate, Hydrogenated Lecithin, Gellan Gum, Sodium Phytate, Cellulose, Caprylic Capric Triglyceride, Panthenol, Cyanocobalamin, Polyglutamic Acid, 3-O-Ethyl Ascorbic Acid, Ceramide Np, Dextrin, Asiaticoside, Madecassic Acid, Asiatic Acid, Dimethylsilanol Hyaluronate, Hydrolyzed Sodium Hyaluronate, Potassium Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Sodium Hyaluronate Crosspolymer, Sodium Hyaluronate Dimethylsilanol, Sodium Acetylated Hyaluronate, Xanthan Gum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/combination-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/combination-skin
- France: https://lovi.care/skincare/fr/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/combination-skin