# Alastin Ultra Nourishing Moisturizer for mature skin

**Lovi Fit: Superior fit for mature skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/p/alastin/ultra-nourishing-moisturizer/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Alastin](https://lovi.care/skincare/brands/alastin)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/best/moisturizers)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best moisturizers for mature skin.

## Why this fit

- Excellent for your normal skin, this moisturizer effectively targets wrinkles and fine lines with Palmitoyl Tripeptide-1 and Palmitoyl Hexapeptide-12 to support collagen production and skin elasticity. Glycerin and Tremella Fuciformis Sporocarp Extract provide superior hydration and barrier support, aligning perfectly with your skin's needs.
- The formula's rich blend of emollients like Caprylic Capric Triglyceride and humectants ensures deep moisturization and enhances barrier resilience for your normal skin.
- Safety is well-addressed with soothing ingredients such as Bisabolol and Oat Kernel Extract, ensuring no irritation for your normal skin.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/alastin/ultra-nourishing-moisturizer/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/p/alastin/ultra-nourishing-moisturizer/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/p/alastin/ultra-nourishing-moisturizer/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/p/alastin/ultra-nourishing-moisturizer/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/p/alastin/ultra-nourishing-moisturizer/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/p/alastin/ultra-nourishing-moisturizer/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/p/alastin/ultra-nourishing-moisturizer/for/mature-skin): Superior (this page)
- [Dry sensitive skin](https://lovi.care/skincare/p/alastin/ultra-nourishing-moisturizer/for/dry-sensitive-skin): Superior
- [Oily acne-prone skin](https://lovi.care/skincare/p/alastin/ultra-nourishing-moisturizer/for/oily-acne-prone-skin): Average

## Key ingredients

Trihex Technology, Palmitoyl Tripeptide-1, Glycerin, Tremella Fuciformis Sporocarp Extract, Helianthus Annuus Extract Sunflower Extract

## What the research says

- Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Palmitoyl hexapeptide-12 permeates the stratum corneum and epidermis, initiating gel formation via endogenous ions and strengthening and repairing the skin barrier after delipidation in human skin. ([ACS Applied Bio Materials, 2025](https://pubmed.ncbi.nlm.nih.gov/39964201/))
- Topical application of an emollient emulsion containing 15.0% caprylic/capric triglyceride doubled the amount of urocanic acid isomers and increased skin hydration with reduced transepidermal water loss in healthy subjects, though it did not prevent ultraviolet-induced urocanic acid isomerization. ([Life, 2023](https://pubmed.ncbi.nlm.nih.gov/37109405/))
- Pre-conditioning with TriHex Technology Serum Nectar 2.0 improved healing, global skin health, and extracellular matrix remodeling compared to a vehicle in 5 patients undergoing elective facelift surgery. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41358458/))
- Topical ReFORM & RePAIR COMPLEX with TriHex Technology significantly accelerated the resolution of internal fibrous banding and improved external scar quality compared with comparators in patients undergoing body contouring procedures. ([Aesthetic Surgery Journal. Open Forum, 2026](https://pubmed.ncbi.nlm.nih.gov/41608079/))
- Topical application of TransFORM Body Treatment significantly increased adipose volume loss compared to placebo in 15 subjects following abdominal cryolipolysis or radiofrequency procedures over 12 weeks. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32009299/))
- A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo. ([Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/))
- Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components. ([International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42683869/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Snow mushroom alcohol-based hand rub gel significantly improved skin moisture better than the placebo through 180 minutes while maintaining comparable antiseptic efficacy in 20 human volunteers. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/32531816/))
- Tremella fuciformis extract demonstrates potential cutaneous benefits including skin antiaging, photoprotection, wound healing, and barrier protection based on in vitro and animal models. ([Archives of Dermatological Research, 2023](https://pubmed.ncbi.nlm.nih.gov/36757441/))
- Tremella fuciformis inhibits melanogenesis by decreasing melanin content and tyrosinase expression in B16F10 cells while promoting wound healing in human HaCaT keratinocytes and Detroit 551 fibroblasts. ([In Vivo, 2022](https://pubmed.ncbi.nlm.nih.gov/35241526/))

## What reviewers say

This moisturizer is highly rated for providing deep, lasting hydration without a heavy feel, making it suitable for dry, sensitive, and aging skin. It is frequently praised for improving skin texture, calming redness, and supporting the skin barrier, and is often used as a makeup base or for post-procedure care. The product is considered expensive by many users, and its availability is sometimes limited.

- Liked: Deeply hydrating (mostly mentioned)
- Liked: Lightweight feel (often mentioned)
- Liked: Sensitive skin friendly (often mentioned)
- Disliked: Expensive product (often mentioned)
- Liked: Improves texture (sometimes noted)
- Disliked: Limited availability (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help smooth fine lines.
- Apply this product after your toner and serum, but before your SPF in the morning. Follow your cleanser and toner steps to keep your skin balanced.
- Gently press a small amount into your face and neck. Avoid rubbing the skin too harshly to prevent extra tension.
- Apply the moisturizer on slightly damp skin to help lock in extra moisture. Clean skin helps the product absorb much more evenly.
- Avoid the sensitive eye area during application. Do a quick patch test before your very first use to stay safe.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Alastin Ultra Nourishing Moisturizer one of the best fits for mature skin?

This moisturizer is an exceptional fit because Palmitoyl Tripeptide-1 and Palmitoyl Hexapeptide-12 target wrinkles and fine lines to support collagen production and firmness. Glycerin and Tremella Fuciformis Sporocarp Extract provide deep hydration and barrier support, while Bisabolol and oat kernel extract keep skin calm and comfortable.
Sources: [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this cream a good fit for mature skin?

Palmitoyl Tripeptide-1 and Palmitoyl Hexapeptide-12 make this cream a great fit because they support collagen production to help smooth out wrinkles and firm up mature skin. Glycerin and Tremella Fuciformis Sporocarp Extract add deep hydration, while soothing ingredients like Bisabolol and Oat Kernel Extract help keep the skin calm and comfortable.
Sources: [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/), [ACS Applied Bio Materials, 2025](https://pubmed.ncbi.nlm.nih.gov/39964201/)

### What does Trihex Technology do for mature skin?

Trihex Technology helps clear out damaged collagen and elastin in mature skin while supporting the production of fresh, healthy fibers to restore firmness and smooth the look of lines. Because it helps rebuild the underlying support network, this type of formula typically needs to include peptides and antioxidants to properly target the structural breakdown seen in aging skin.
Sources: [Skin Pharmacology and Physiology, 2014](https://pubmed.ncbi.nlm.nih.gov/24401291/), [Journal of Drugs in Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30909351/)

### What does Palmitoyl Tripeptide-1 do for mature skin?

Palmitoyl tripeptide-1 helps improve firmness, smooths out wrinkles, and enhances skin brightness when used as part of an anti-aging routine. Studies show that when applied at night or combined with complementary peptides, it supports collagen production to make mature skin look more firm and elastic.
Sources: [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/), [International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42683869/)

### Where does this cream go in a skincare routine for mature skin?

This moisturizer goes near the end of your morning routine before sunscreen, and as the final step in your evening routine. Using it daily helps deeply hydrate mature skin, smooth fine lines, and support firmness.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/)

### Can I use it with retinol, and in what order?

You can use this moisturizer with retinol to help keep your skin comfortable and smooth. Apply your retinol treatment first, let it sink in, and then smooth on the moisturizer to lock in hydration.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this cream?

This cream fits mature skin very well and is gentle enough to use twice a day as part of your morning and evening routine. Regular daily use helps smooth fine lines, supports collagen production, and keeps dry skin deeply moisturized.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Journal of Drugs in Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/26151786/)

### Can it clog pores, cause breakouts or purging for mature skin?

This moisturizer is unlikely to clog pores or cause breakouts for mature skin, as its soothing ingredients like bisabolol and oat kernel extract help prevent irritation. It also does not contain active exfoliating ingredients, so it will not cause purging.

### Can I use it around the eyes or on my body?

This moisturizer is safe and effective to use on the thin skin around the eyes and on the body to smooth wrinkles and provide deep hydration. Its gentle ingredients and rich blend of moisturizers are well-suited to care for delicate areas without causing irritation.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [European Journal of Pharmaceutics and Biopharmaceutics, 2014](https://pubmed.ncbi.nlm.nih.gov/24056055/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for mature skin

- [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/mature-skin) — Superior fit — $22.00 at Amazon
- [Obagi Hydrate Luxe Moisture-Rich Cream](https://lovi.care/skincare/p/obagi/hydrate-luxe/for/mature-skin) — Superior fit — $85.00 at Amazon
- [L'Occitane Immortelle Divine Cream](https://lovi.care/skincare/p/l-occitane/immortelle-divine-cream/for/mature-skin) — Superior fit — $120.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — $28.08 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — $17.00 at Amazon
- SPF: [ISDIN Eryfotona Actinica SPF 50+](https://lovi.care/skincare/p/isdin/eryfotona-actinica-spf-50/for/mature-skin) — Superior fit — $46.00 at Amazon

## Where to buy

No store in United States has a checked price for this product, so the page shows none.

## Ingredients

Water, Caprylic Capric Triglyceride, Caprylyl Methicone, Glycerin, Cetearyl Alcohol, Dimethicone, Glyceryl Oleate Citrate, Glyceryl Stearate, Potassium Cocoyl Hydrolyzed Oat Protein, Palmitoyl Tripeptide-1, Palmitoyl Hexapeptide-12, Helianthus Annuus Extract Sunflower Extract, Avena Sativa Kernel Extract Oat Kernel Extract, Tremella Fuciformis Sporocarp Extract, Rice Bran Extract, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract, Betaine, Bisabolol, Linoleic Acid, Tocopherol, Glyceryl Oleate, Caprylyl Glycol, Glycine Soja Soybean Sterols, Disodium Edta, Polyacrylate-13, Polyisobutene, Polysorbate 20, Caprylhydroxamic Acid, Ethylhexylglycerin, Phenoxyethanol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/alastin/ultra-nourishing-moisturizer/for/mature-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/alastin/ultra-nourishing-moisturizer/for/mature-skin
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- Germany: https://lovi.care/skincare/de/p/alastin/ultra-nourishing-moisturizer/for/mature-skin
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- United Arab Emirates: https://lovi.care/skincare/ae/p/alastin/ultra-nourishing-moisturizer/for/mature-skin