Alastin Skincare HA Immerse Serum for combination skin

Sodium Hyaluronate
Tremella Fuciformis Sporocarp Extract Silver Ear Mushroom Extract
Hexapeptide-11
Lactoferrin
Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate
High
- HighCombination Skin Fit
- HighEffectiveness
- ExcellentSafety
One of the best moisturizers for combination skin.
This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Highly suitable for your combination skin, this serum utilizes Glycerin and Sodium Hyaluronate to provide excellent humectant action, effectively hydrating and plumping your skin to address oily shine.
- The inclusion of Tremella Fuciformis Sporocarp Extract further enhances its moisturizing capabilities, offering moderate hydration benefits.
- The safety profile is excellent, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components.
How to apply
- Use this moisturizer in your AM and PM routine every day to control shine. Always pair with SPF in the morning.
- Apply this moisturizer after your cleanser and toner, right before your morning SPF.
- Gently press a small amount of the moisturizer into your skin and avoid harsh rubbing. Let it ⏳absorb for a minute.
- Apply the moisturizer on slightly damp skin to help it lock in moisture better. This keeps your combination skin balanced.
- Avoid the eye area when applying the moisturizer. Do a patch test before your first use.
People Say
★4.7Overall rating based on 400+ reviewsThis serum is widely celebrated for its transformative hydrating properties, with users reporting significant improvements in skin suppleness, radiance, and the reduction of fine lines. It is particularly favored by those with dry or mature skin for its ability to provide a "plumped" and youthful appearance without causing irritation or leaving a heavy, sticky residue.
Highlights
Instant hydration Mostly Mentioned
- “Hydrates and plumps instantly”
- “Sweet, sweet relief”
- “Quenches all the dryness”
Layers well Often Mentioned
- “Doesn't pill under makeup”
- “Layers well with other products”
- “No mask-like feeling”
Non-greasy texture Often Mentioned
- “No greasy residue”
- “Lightweight, absorbs completely”
- “Smooth and silky”
High price Often Mentioned
- “A little pricey”
- “Triple dollar sign territory”
- “Worth the investment but pricey”
Smooths fine lines Sometimes Noted
- “Less creases”
- “Lines look smoother”
- “Don't see them when I use this”
Packaging issues Rarely Noted
- “Pop-up part stops working”
- “Inner chamber came loose”
- “Rendered the spout useless”
Product longevity Rarely Noted
- “Wish it lasted longer”
- “Need to reapply during the day”
Sources: lovi.care, alastin.com, ellemesmedspa.com, lovelyskin.com, newbeauty.com, nicolesimonek.com, and more
Questions and answers
What makes Alastin HA Immerse Serum a great fit for combination skin?
Which ingredients make this serum a good fit for combination skin?
This serum is a great fit for your combination skin because it uses glycerin and sodium hyaluronate to deeply hydrate and plump your skin while helping to control oily shine. It also includes silver ear mushroom extract for extra moisture, and lactoferrin, which helps regulate oil production and calm inflammation.
What does Hyaluronic Acid do for combination skin?
Hyaluronic acid is a great fit for combination skin because it quenches dry areas with a boost of hydration while keeping oily zones balanced. Regular use helps smooth out fine lines and makes your skin feel soft and plump without causing irritation.
Dermatology and Therapy, 2021Journal of Drugs in Dermatology, 2011
What does Tremella Fuciformis Sporocarp Extract do for combination skin?
Tremella Fuciformis Sporocarp Extract helps combination skin by holding onto moisture and protecting the skin barrier, leaving dry areas soft while staying light on oily spots. It also provides antioxidant support and helps keep the skin looking smooth.
Bioscience, Biotechnology, and Biochemistry, 2014Archives of Dermatological Research, 2023
Where does this serum go in a skincare routine for combination skin?
This serum goes in the evening routine after cleansing and before moisturizing, though some serums may also be used in the morning or twice a day. Applying it at night helps keep your routine simple and provides extra safety around sun exposure.
Can I use this serum with retinol, and in what order?
You can use this serum with retinol, applying the serum before your retinol to keep your skin plump and hydrated while reducing the likelihood of dryness or irritation.
Cutis, 2006Clinical, Cosmetic and Investigational Dermatology, 2017
How often should I use this serum?
You can use this serum in your evening routine every day. Its gentle formula is very safe for daily use and helps keep your skin feeling hydrated and smooth.
Health Science Reports, 2021Clinical, Cosmetic and Investigational Dermatology, 2017
Can this serum clog pores, cause breakouts or purging for combination skin?
This serum is unlikely to clog pores or cause breakouts on combination skin because its gentle formula avoids harsh ingredients and features soothing components that help keep skin calm. It also includes lactoferrin, which may help balance oil production.
Can I use this serum around the eyes or on my body?
You can use this serum around the eyes, where the skin is particularly thin, as its gentle formula has an excellent safety profile with very good skin tolerance. Regular application of products containing hyaluronic acid helps reduce wrinkles in this delicate area without causing irritation.
Is this serum fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Lactoferrin treatment decreased lipid content and attenuated the mRNA expression of lipid metabolism and inflammatory genes in SZ95 human sebocytes, and reduced inflammation, lipid production, and sebaceous gland cell proliferation while increasing apoptosis in a mouse model of acne.
Journal of Cosmetic Dermatology, 2023Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019Snow mushroom alcohol-based hand rub gel significantly improved skin moisture better than the placebo through 180 minutes while maintaining comparable antiseptic efficacy in 20 human volunteers.
Journal of Cosmetic Dermatology, 2021Tremella fuciformis extract demonstrates potential cutaneous benefits including skin antiaging, photoprotection, wound healing, and barrier protection based on in vitro and animal models.
Archives of Dermatological Research, 2023Tremella fuciformis inhibits melanogenesis by decreasing melanin content and tyrosinase expression in B16F10 cells while promoting wound healing in human HaCaT keratinocytes and Detroit 551 fibroblasts.
In Vivo, 2022Hexapeptide-11 activated proteasome, autophagy, chaperones, and antioxidant response genes, protected fibroblasts against oxidative-stress-mediated premature cellular senescence, and improved skin elasticity in human subjects.
Redox Biology, 2015Hexapeptide-11 reversibly downregulated ATM and p53 protein expression in intrinsically aged fibroblasts, extrinsically aged fibroblasts, and extrinsically aged dermal papillae cells at concentrations between 0.1% and 1.0% in vitro, thereby influencing the onset of cellular senescence.
Journal of Cosmetic Science, 2013The combination of sodium ascorbate and lactoferrin demonstrated a significant synergistic effect on tropoelastin stimulation with intact and increased elastin fibers compared to single treatments in an ex vivo human skin model.
Journal of Cosmetic Dermatology, 2024Colostrum-derived exosome-encapsulated lactoferrin promoted cell viability and migration while reducing pro-inflammatory cytokines and phosphorylated JNK in mouse NIH/3T3 and human HS-68 fibroblasts treated with lipopolysaccharide.
Current Issues in Molecular Biology, 2025Supramolecular collagen nanoparticles composed of lactoferrin, recombinant human collagen, and palmitoyl tripeptide-5 improved transdermal efficiency by 69.90% and demonstrated moisturizing, whitening, wrinkle reduction, and firming effects.
Colloids and Surfaces. B, Biointerfaces, 2025
Ingredients
Water, Glycerin, Polyacrylate-13, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Octapeptide-45, Hexapeptide-11, Tremella Fuciformis Sporocarp Extract Silver Ear Mushroom Extract, Lactoferrin, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Xylitol, Propanediol, Anhydroxylitol, Xylitylglucoside, Phosphatidylserine, Glucose, Hydroxymethoxyphenyl Decanone, Tocopherol, Ascorbyl Palmitate, Dimethicone, Caprylyl Methicone, Caprylic Capric Triglyceride, Polyisobutene, Caprylyl Glycol, Disodium Edta, Betaine, Polysorbate 20, Ethylhexylglycerin, Caprylhydroxamic Acid, Sorbitan Isostearate, Helianthus Annuus Seed Oil Sunflower Seed Oil, Lecithin, Pentylene Glycol, Magnesium Chloride, Phenoxyethanol, Potassium Sorbate, Sodium Hydroxide
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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