Advanced Clinicals HYALURONIC SERUM for mature skin
Hyaluronic Acid
Glycerin
Aloe Barbadensis Leaf JuiceAverage
- HighNormal Skin Fit
- AverageEffectiveness
- HighSafety
Works for mature skin; other moisturizers fit it better.
- Clinical, Cosmetic and Investigational Dermatology, 2017
- International Journal of Cosmetic Science, 2019
This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate moisturizing for your normal skin due to the humectant action of glycerin and hyaluronic acid, which hydrate effectively but do not directly address your wrinkles and fine lines.
- The presence of Pyrus Malus Fruit Extract and Camellia Sinensis Leaf Extract provides general skincare benefits, but these are not targeted for anti-aging concerns.
- The product is safe for your normal skin, as it lacks harsh ingredients and poses no irritation risks.
How to apply
- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help smooth fine lines.
- Apply this product after your toner and serum, but before your SPF in the morning. Follow your cleanser and toner steps to keep your skin balanced.
- Gently press a small amount into your face and neck. Avoid rubbing the skin too harshly to prevent extra tension.
- Apply the moisturizer on slightly damp skin to help lock in extra moisture. Clean skin helps the product absorb much more evenly.
- Avoid the sensitive eye area during application. Do a quick patch test before your very first use to stay safe.
People Say
★4.8Overall rating based on 800+ reviewsThis serum is highly effective for providing instant and deep hydration, improving skin texture, and reducing the appearance of fine lines, making it a popular choice for dry, dehydrated, and aging skin types. Users frequently experience a plumper complexion and diminished fine lines. Some users note a slightly sticky finish or a strong fragrance.
Highlights
Deeply hydrating Mostly Mentioned
- “instant hydration for dry skin”
- “keeps my skin feeling hydrated”
- “It moisturizes. It is used daily.”
- “It became less dehydrated”
Great value Often Mentioned
- “EXCELLENT PRODUCT FOR PRICE”
- “Great product at a great price”
- “superb price”
- “more reasonably priced than other products”
Reduces fine lines Often Mentioned
- “reducing the appearance of my laugh lines”
- “fine lines are less noticeable”
- “visibly plumps skin”
- “smooths fine lines”
Absorbs quickly Sometimes Noted
- “absorbs well”
- “gets soaked up completely”
- “still absorbs quickly!”
- “absorbs quickly without any greasy residue”
Noticeable fragrance Sometimes Noted
- “the limonene is pretty strong”
- “switch to something with less fragrance”
- “The scent is a bit like vitamin B complex.”
- “strong scent”
Slightly sticky finish Sometimes Noted
- “It's a little sticky but It absorbs well.”
- “sticky. It provides good hydration”
- “sticky”
Potential ingredient concerns Rarely Noted
- “if I used this when my barrier didn't exist it probably would have irritated me”
- “I am surprised that it didn't break me out that time”
- “I don't know what happened to my skin after I learn to analyze the ingredients”
Sources: lovi.care, walmart.com, ebay.com, iherb.com, skinsort.com, desertcart.ae, and more
Questions and answers
How well does Advanced Clinicals Hyaluronic Serum work for mature skin?
Advanced Clinicals Hyaluronic Serum works moderately well for mature skin by keeping it hydrated with glycerin and hyaluronic acid, though it lacks specific ingredients to target wrinkles and fine lines. To truly fit mature skin, a moisturizing treatment needs targeted anti-wrinkle ingredients alongside hydrating agents to effectively smooth and nourish the skin.
Which ingredients make this serum a good fit for mature skin?
This serum helps hydrate your skin through the action of hyaluronic acid and glycerin, though it does not directly target wrinkles and fine lines. To better suit mature skin, a product of this type needs effective anti-wrinkle ingredients and skin-repairing ingredients that enhance vitality and radiance.
What does Hyaluronic Acid do for mature skin?
Hyaluronic acid helps mature skin by deeply boosting moisture, improving elasticity, and smoothing the appearance of fine lines and wrinkles. Regular use keeps the skin looking plump and soft while supporting overall firmness and hydration.
Journal of Drugs in Dermatology, 2011Skin Research and Technology, 2024
What does Glycerin do for mature skin?
Glycerin helps keep mature skin feeling soft and smooth by drawing moisture into the outer layer and locking it in. This daily hydration boost supports the skin barrier, keeping dry areas comfortable and protected against irritation.
The British Journal of Dermatology, 2008Clinical, Cosmetic and Investigational Dermatology, 2017
Where does this serum go in a skincare routine for mature skin?
Apply this serum in your evening routine, putting it on after cleansing and before your moisturizer. This timing helps keep your skin safe around sun exposure while providing hydration.
Can I use this serum with retinol, and in what order?
You can use this serum with retinol by applying the serum first to hydrate your skin before following with your retinol treatment. This approach helps support skin comfort, though mature skin also needs targeted anti-aging ingredients and firming peptides to effectively smooth wrinkles and fine lines.
How often should I use this serum?
You can use this treatment in the evening as part of your routine. This product of this type needs targeted anti-aging ingredients and firming peptides to effectively care for mature skin.
Can this serum clog pores, cause breakouts or purging for mature skin?
This serum is unlikely to clog pores or cause breakouts for mature skin, as it has a safe formula without harsh ingredients. However, to truly care for mature skin, a product of this type needs firming ingredients and targeted anti-aging actives that smooth out wrinkles and fine lines.
Can I use this serum around the eyes or on my body?
Yes, you can use this serum on your body and around your eyes, as it is safe for the skin and poses no irritation risks. Products of this type need targeted anti-aging ingredients and rich moisturizers to properly care for mature skin and reduce wrinkles and fine lines.
Is this serum fragrance-free and alcohol-free?
It has no drying alcohol and contains fragrance (limonene, geraniol, hexyl cinnamal, and linalool).
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017A cosmetic cream with 6% standardized wild apple fruit extract and a conventional emulsifier demonstrated stable antioxidant activity of 19.25 %RSC, increased skin moisturization, and a decreased melanin index by -31.40 without causing skin irritation.
International Journal of Cosmetic Science, 2019Dermocosmetic creams containing 6%, 12%, and 15% of standardized wild apple fruit ultrasonic extract increased skin hydration proportionally to extract concentration after 28 days of application on healthy volunteers without altering transepidermal water loss or skin pH.
Journal of Cosmetic Dermatology, 2022Topical low-dose green tea extract reduces UVB-induced p53 expression and apoptosis in human skin keratinocytes compared to placebo.
Experimental Dermatology, 2009Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.
Journal of Cosmetic Dermatology, 2020Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.
International Journal of Cosmetic Science, 2001Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.
Journal of Drugs in Dermatology, 2012A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo.
Clinical Pharmacology, 2018Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief.
Plastic and Reconstructive Surgery, 2018Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo.
Journal of Alternative and Complementary Medicine, 2010
Why other moisturizers fit mature skin better
Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.
Journal of Cosmetic Dermatology, 2021Treatment with a combination of niacinamide and hyaluronic acid improved skin aging signs and demonstrated a senomorphic effect by decreasing SASP and autocrine signaling genes in women.
Scientific Reports, 2024
Ingredients
Water, Ethoxydiglycol, Glycerin, Pyrus Malus Fruit Extract, Peg-12 Dimethicone, Hyaluronic Acid, Chondrus Crispus Extract, Camellia Sinensis Leaf Extract, Aloe Barbadensis Leaf Juice, Sodium Carboxymethyl Beta-Glucan, Epilobium Angustifolium Stem Extract Flower Leaf, Tocopheryl Acetate, Xanthan Gum, Phenoxyethanol, Maltodextrin, Tetrasodium Glutamate Diacetate, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Citric Acid, Limonene, Geraniol, Hexyl Cinnamal, Linalool
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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