# Advanced Clinicals HYALURONIC SERUM for dry sensitive skin

**Lovi Fit: Average fit for dry sensitive skin.**
Dry Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/p/advanced-clinicals/hyaluronic-serum/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Advanced Clinicals](https://lovi.care/skincare/brands/advanced-clinicals)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/best/moisturizers)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry sensitive skin; other moisturizers fit it better.

## Why this fit

- Offers moderate hydration for your dry or flaky skin, as glycerin and hyaluronic acid provide humectant action while chondrus crispus extract and aloe barbadensis leaf juice offer emollient benefits.
- This formula is highly suitable for dry skin due to its humectant and emollient ingredients, though it does not offer targeted treatment for flakiness.
- The safety profile is excellent, with no risks of irritation for your dry and sensitive skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/advanced-clinicals/hyaluronic-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/p/advanced-clinicals/hyaluronic-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/p/advanced-clinicals/hyaluronic-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/p/advanced-clinicals/hyaluronic-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/p/advanced-clinicals/hyaluronic-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/p/advanced-clinicals/hyaluronic-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/p/advanced-clinicals/hyaluronic-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/p/advanced-clinicals/hyaluronic-serum/for/dry-sensitive-skin): Average (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/p/advanced-clinicals/hyaluronic-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Hyaluronic Acid, Glycerin, Aloe Barbadensis Leaf Juice

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- κ-carrageenan tetrasaccharide treatment protects against particulate matter-induced oxidative stress, inflammation, and skin barrier dysfunction in human HaCaT keratinocytes by chelating metal ions and modulating STAT3, PI3K/AKT, and PPAR-γ pathways. ([International Journal of Biological Macromolecules, 2025](https://pubmed.ncbi.nlm.nih.gov/39880261/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief. ([Plastic and Reconstructive Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29649056/))
- Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo. ([Journal of Alternative and Complementary Medicine, 2010](https://pubmed.ncbi.nlm.nih.gov/20569031/))

## Why other moisturizers fit dry sensitive skin better

- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- A cream containing panthenol, prebiotics, and probiotic lysate improved facial sensitive skin symptoms and skin barrier function in 110 participants over 28 days. ([Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38186043/))
- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))

## What reviewers say

This serum is highly effective for providing instant and deep hydration, improving skin texture, and reducing the appearance of fine lines, making it a popular choice for dry, dehydrated, and aging skin types. Users frequently experience a plumper complexion and diminished fine lines. Some users note a slightly sticky finish or a strong fragrance.

- Liked: Deeply hydrating (mostly mentioned)
- Liked: Great value (often mentioned)
- Liked: Reduces fine lines (often mentioned)
- Liked: Absorbs quickly (sometimes noted)
- Disliked: Noticeable fragrance (sometimes noted)
- Disliked: Slightly sticky finish (sometimes noted)
- Disliked: Potential ingredient concerns (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine. Start using this moisturizer 3 times a week and move to daily use if your dry skin tolerates it well.
- Apply this moisturizer after cleansing and toner in the morning, or after your serum in the evening. Always pair it with SPF in the morning.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing it harshly to protect your sensitive skin.
- Apply the moisturizer on slightly damp skin to help with hydration absorption. This also works well for dry and flaky skin types.
- Do a patch test before your first use. Avoid the eye area to prevent any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Advanced Clinicals Hyaluronic Serum work for dry sensitive skin?

This serum works reasonably well for your dry sensitive skin, offering moderate hydration and a safe formula without harsh ingredients. To fit this skin type best, a product of this type needs multiple forms of hyaluronic acid, pro vitamin B5, and ceramides for deep moisture and barrier support.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for dry sensitive skin?

Hyaluronic acid and glycerin help make this serum a good fit by pulling moisture into dry skin, while aloe leaf juice helps calm it. To fit this skin type even better, a moisturizing treatment needs multiple forms of hyaluronic acid, pro vitamin B5, and ceramides for deep hydration and barrier support.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Hyaluronic Acid do for dry sensitive skin?

Hyaluronic acid is a great fit for dry, sensitive skin because it brings a large boost in hydration, making the skin feel soft and smooth while improving barrier function. It helps calm tightness and dryness, and is unlikely to cause irritation.
Sources: [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/), [Dermatology and Therapy, 2021](https://pubmed.ncbi.nlm.nih.gov/34176098/)

### What does Glycerin do for dry sensitive skin?

Glycerin helps dry sensitive skin by drawing moisture into the skin and keeping it there, making the skin soft and smooth. It is very gentle and unlikely to cause irritation while improving how well the skin holds onto water. This type of skin needs ingredients that boost hydration and repair the barrier without causing stinging.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/)

### Where does this serum go in a skincare routine for dry sensitive skin?

This serum goes in the evening routine, placed after your cleanser and toner and before your moisturizer. Putting it in the evening keeps things simple and avoids extra safety concerns around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum before your retinol product to help keep your dry sensitive skin comfortable. This type of product needs rich moisturizing ingredients like ceramides and nourishing oils to fully support and protect sensitive skin.

### How often should I use this serum?

Use this serum in your evening routine for simplicity and extra safety around sun exposure. If your dry sensitive skin tolerates it well and you see good results, you may carefully use it more often.

### Can this serum clog pores, cause breakouts or purging for dry sensitive skin?

This serum is unlikely to clog pores or cause irritation for your dry sensitive skin due to the absence of harsh ingredients. To care for skin like this, a product needs gentle soothing ingredients and rich moisturizers to keep the skin calm and comfortable.

### Can I use this serum around the eyes or on my body?

You can use this serum on the thin skin around your eyes and on your body because its safety profile is excellent and it is unlikely to cause irritation. However, a product for dry sensitive skin needs stronger ingredients like targeted moisturizers and rich emollients to better handle flakiness.

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (limonene, geraniol, hexyl cinnamal, and linalool).

## Alternatives for dry sensitive skin

- [COSRX Hydrium Triple Hyaluronic Moisture Ampoule](https://lovi.care/skincare/p/cosrx/hydrium-triple-hyaluronic-moisture-ampoule/for/dry-sensitive-skin) — Superior fit — $19.99 at Amazon
- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/dry-sensitive-skin) — High fit — $22.25 at Amazon
- [Kiehl's Midnight Recovery Concentrate](https://lovi.care/skincare/p/kiehl-s/midnight-recovery-concentrate/for/dry-sensitive-skin) — High fit — $139.00 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — $16.97 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/p/clarins/soothing-toning-lotion/for/dry-sensitive-skin) — Superior fit — $28.05 at Amazon
- Moisturizer with Sun Protection: [d'Alba UVessence Mild Waterfull Sun Cream SPF 50](https://lovi.care/skincare/p/d-alba/uvessence-mild-waterfull-sun-cream-spf-50/for/dry-sensitive-skin) — Superior fit — $18.99 at Amazon

## Where to buy

No store in United States has a checked price for this product, so the page shows none.

## Ingredients

Water, Ethoxydiglycol, Glycerin, Pyrus Malus Fruit Extract, Peg-12 Dimethicone, Hyaluronic Acid, Chondrus Crispus Extract, Camellia Sinensis Leaf Extract, Aloe Barbadensis Leaf Juice, Sodium Carboxymethyl Beta-Glucan, Epilobium Angustifolium Stem Extract Flower Leaf, Tocopheryl Acetate, Xanthan Gum, Phenoxyethanol, Maltodextrin, Tetrasodium Glutamate Diacetate, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Citric Acid, Limonene, Geraniol, Hexyl Cinnamal, Linalool
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/advanced-clinicals/hyaluronic-serum/for/dry-sensitive-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/advanced-clinicals/hyaluronic-serum/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/advanced-clinicals/hyaluronic-serum/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/advanced-clinicals/hyaluronic-serum/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/advanced-clinicals/hyaluronic-serum/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/advanced-clinicals/hyaluronic-serum/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/advanced-clinicals/hyaluronic-serum/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/advanced-clinicals/hyaluronic-serum/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/advanced-clinicals/hyaluronic-serum/for/dry-sensitive-skin
- Australia: https://lovi.care/skincare/au/p/advanced-clinicals/hyaluronic-serum/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/advanced-clinicals/hyaluronic-serum/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/advanced-clinicals/hyaluronic-serum/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/advanced-clinicals/hyaluronic-serum/for/dry-sensitive-skin