# 47 Skin Serum for sensitive skin

**Lovi Fit: Average fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/p/47-skin/serum/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [47 Skin](https://lovi.care/skincare/brands/47-skin)
Category: [Serums and treatments](https://lovi.care/skincare/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for sensitive skin; other serums fit it better.

## Why this fit

- Suitable for normal skin, this serum utilizes glycerin and azelaic acid to hydrate and reduce inflammation, maintaining skin balance.
- While it offers general skincare benefits, it lacks specialized ingredients like niacinamide or centella asiatica to specifically target your redness and irritation.
- The formulation is safe for your sensitive skin, as it contains no harsh or prohibited ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/47-skin/serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/p/47-skin/serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/p/47-skin/serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/p/47-skin/serum/for/sensitive-skin): Average (this page)
- [Acne-prone skin](https://lovi.care/skincare/p/47-skin/serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/p/47-skin/serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/p/47-skin/serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/p/47-skin/serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/p/47-skin/serum/for/oily-acne-prone-skin): Average

## Key ingredients

Silver Chitoderm, Azelaic Acid, Glycerin, Dimethicone

## What the research says

- Application of 15% azelaic acid gel significantly reduced post-inflammatory erythema and hyperpigmentation, decreased hemoglobin and melanin content, improved quality of life, and contributed to acne improvement in patients with mild to moderate acne compared to placebo. ([Dermatology and Therapy, 2024](https://pubmed.ncbi.nlm.nih.gov/38734843/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Azelaic acid nanocrystal hydrogel 10% achieved a higher success rate and greater lesion reduction than azelaic acid cream 20% in patients with mild to moderate facial acne. ([Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/))
- Topical application of a dermocosmetic containing Myrtus communis extract and azelaic acid reduced acne relapses and helped maintain remission compared to a light moisturizing cream in adult females in the acne maintenance phase over 16 weeks. ([Journal of the European Academy of Dermatology and Venereology, 2023](https://pubmed.ncbi.nlm.nih.gov/36729399/))
- Topical administration of 20% azelaic acid cream and 5% tranexamic acid solution comparably improved acne-related postinflammatory hyperpigmentation in patients with acne vulgaris, while tranexamic acid demonstrated a significantly better safety profile at week 4. ([Journal of Research in Medical Sciences, 2023](https://pubmed.ncbi.nlm.nih.gov/37213446/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Wearing an N95 mask alone compared to using dimethicone cream or hydrocolloid dressing caused more adverse skin reactions among 73 military health care workers, with no significant differences in fit test failure rates between groups. ([Military Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38771104/))
- A dimethicone skin protectant lotion significantly decreased visual scoring and transepidermal water loss compared to vehicle control and SLS-only treated sites in 12 healthy humans exposed to sodium lauryl sulfate. ([Skin Research and Technology, 2000](https://pubmed.ncbi.nlm.nih.gov/11428946/))
- Treatment with a moisturizer containing dimethicone and glycerine increased epidermal thickness by 0.019 mm, improved barrier function by decreasing transepidermal water loss by 13%, decreased melanin intensity, and induced keratins 6 and 16 in fifteen women with moderately photoaged forearms. ([Clinical and Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17137484/))

## Why other serums fit sensitive skin better

- Topical application of TAT-SOD significantly suppresses UVB-induced erythema formation, blood flow rise, and apoptotic sunburn cell formation in human volunteers compared to a vehicle control. ([European Journal of Pharmaceutics and Biopharmaceutics, 2016](https://pubmed.ncbi.nlm.nih.gov/27460952/))

## What reviewers say

Based on a very large amount of data, this serum is highly effective for clearing active breakouts and fading acne scars without causing dryness. Thousands of users report significant improvements in acne and redness, with many experiencing their clearest skin. A smaller number of users found it ineffective for hormonal acne or saw no visible changes. The product is also noted for its hydrating properties and pleasant texture, though some find it expensive for the size and a few sensitive-skinned individuals experienced irritation from the scent.

- Liked: Clears breakouts (mostly mentioned)
- Liked: Fades scarring (often mentioned)
- Liked: Hydrating, non-drying (often mentioned)
- Liked: Pleasant texture (sometimes noted)
- Disliked: High price (sometimes noted)
- Disliked: Ineffective for some (rarely noted)
- Disliked: Irritation/scent (rarely noted)
- Disliked: Subscription issues (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does 47 SKIN Serum work for sensitive skin?

This serum is an average fit for sensitive skin because, while it is safe and hydrating, it lacks specialized ingredients to specifically target redness and irritation. To fit this skin type well, a treatment needs soothing ingredients like niacinamide or centella asiatica.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for sensitive skin?

This serum works for sensitive skin because it uses glycerin and azelaic acid to hydrate and calm redness, helping keep your skin balanced. It is safe to use since it has no harsh ingredients, though a better choice for this skin would include specialized soothing ingredients like niacinamide or centella asiatica.
Sources: [Dermatology and Therapy, 2024](https://pubmed.ncbi.nlm.nih.gov/38734843/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Silver Chitoderm do for sensitive skin?

Silver Chitoderm helps calm sensitive skin and keeps it feeling soft and smooth. It is unlikely to cause irritation and supports a comfortable, balanced feel.

### What does Azelaic Acid do for sensitive skin?

Azelaic acid helps calm sensitive, red, or easily irritated skin by soothing inflammation and reducing redness. It is generally well-tolerated and is unlikely to cause severe reactions, making it a gentle option for skin that flares up easily.
Sources: [Experimental Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20545756/), [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/21637903/)

### Where does it go in a skincare routine for sensitive skin?

This serum goes in the evening routine, after cleansing and soothing toner, and before moisturizer. It is safe for sensitive skin, but to specifically target redness and irritation, a product of this type needs specialized ingredients like niacinamide or centella asiatica.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first and your retinol afterwards during your evening routine, as the formulation is safe and contains no harsh or prohibited ingredients for sensitive skin. To truly calm redness and irritation on sensitive skin, this type of product needs specialized ingredients like niacinamide or centella asiatica.

### How often should I use it?

This treatment is used in the evening routine. A product of this type for sensitive skin needs calming ingredients like niacinamide or centella asiatica to soothe redness and irritation.

### Can this serum clog pores, cause breakouts or purging for sensitive skin?

This serum is unlikely to clog pores or cause purging for sensitive skin since it contains no harsh or prohibited ingredients that disrupt skin balance. However, because it lacks specialized soothing ingredients like niacinamide or centella asiatica, a product of this type for sensitive skin needs calming and barrier-supporting ingredients to truly keep irritation at bay.

### Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for sensitive skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/sensitive-skin) — Superior fit — $53.00 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/p/skinceuticals/c-e-ferulic/for/sensitive-skin) — High fit — $39.99 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/p/neogen-dermalogy/real-vitamin-c-serum/for/sensitive-skin) — High fit — $25.08 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — $28.08 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/p/clarins/soothing-toning-lotion/for/sensitive-skin) — Superior fit — $28.05 at Amazon
- Moisturizer with Sun Protection: [innisfree Daily Mild Sunscreen](https://lovi.care/skincare/p/innisfree/daily-mild-sunscreen/for/sensitive-skin) — Superior fit — $18.00 at Amazon

## Where to buy

- Amazon.com: $44.99 (https://www.amazon.com/dp/B09VQ6JLGR?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
Prices checked 5 Nov 2026.

## Ingredients

Water, Glycerin, Cyclopentasiloxane, Caprylic Capric Triglyceride, Dimethicone, Glyceryl Stearate, Peg-100 Stearate, Cetearyl Alcohol, Silver Chitoderm, Azelaic Acid
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/47-skin/serum/for/sensitive-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/47-skin/serum/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/47-skin/serum/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/47-skin/serum/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/47-skin/serum/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/47-skin/serum/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/47-skin/serum/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/47-skin/serum/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/47-skin/serum/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/47-skin/serum/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/47-skin/serum/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/47-skin/serum/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/47-skin/serum/for/sensitive-skin