ZO Skin Health Enzymatic Peel for mature skin
Glycolic Acid
Bromelain
Papain
Helianthus Annuus Seed Oil Sunflower Seed Oil
Brassica Oleracea Italica ExtractHigh
- HighNormal Skin Fit
- HighEffectiveness
- HighSafety
A great choice for mature skin; a few products fit it even better.
This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers excellent exfoliation for your normal skin, as glycolic acid, bromelain, and papain work synergistically to smooth texture and promote skin renewal, effectively addressing your concerns with wrinkles and fine lines.
- The keratolytic action of these ingredients is well-suited for normal skin, enhancing the product's functionality for your specific goals.
- The formulation is safe for your normal skin, with no reported risks of irritation due to the absence of harsh or prohibited ingredients.
How to apply
- Use this exfoliant product in your PM routine once a week to start, increasing frequency only if your skin tolerates it well. Always apply SPF the next morning to protect your skin.
- Apply this exfoliant product after cleansing and toner, but before your moisturizer. This ensures the best absorption into your skin.
- Gently press 2-3 drops of the exfoliant product into your face, avoiding any rubbing. Let it absorb for a minute before moving to the next step.
- Apply this exfoliant product on completely dry skin to get the best results. This helps your normal skin accept the product smoothly.
- Avoid the sensitive eye area while using this exfoliant product. Do a patch test before your first use and avoid mixing it with strong acids.
People Say
★4.5Overall rating based on 1.8k+ reviewsBased on a very large amount of data, this product is highly praised for its ability to gently exfoliate, leaving skin feeling smoother, brighter, and more radiant without significant downtime. Users frequently report that it effectively addresses dullness, rough texture, and minor sun damage, making it a popular choice for maintaining skin health between professional treatments.
Highlights
Smoother skin texture Mostly Mentioned
- “Skin feels amazingly soft”
- “noticeably smoother”
- “promotes smoother texture”
Brighter complexion Often Mentioned
- “Look renewed”
- “brighter appearance”
- “skin glow”
Easy to use Sometimes Noted
- “Amazing and so simple”
- “perfect at-home treat”
- “simple application”
No visible peeling Sometimes Noted
- “No obvious peeling”
- “minimal downtime”
- “no shedding”
High price point Sometimes Noted
- “Expensive”
- “investment”
- “premium cost”
Requires consistency Sometimes Noted
- “Takes time to see results”
- “needs regular use”
Sun sensitivity Rarely Noted
- “Increases sun sensitivity”
- “must use sunscreen”
Sources: lovi.care, zoskinhealth.com, leboskincare.com, myfacedr.com, dermstreet.com, aptmedicalaesthetics.com, and more
Questions and answers
What makes ZO Skin Health Enzymatic Peel a great fit for mature skin?
This exfoliant treatment is a great fit because glycolic acid, bromelain, and papain work together to smooth texture and encourage skin renewal, which helps target wrinkles and fine lines. This action is well-suited for your skin, and the formula has a very safe profile with no reported irritation risks.
Which ingredients make this exfoliant a good fit for mature skin?
Glycolic acid, bromelain, and papain make this exfoliant a great fit by smoothing texture and helping with wrinkles and fine lines. These ingredients gently sweep away dead skin to leave normal skin looking fresh and renewed.
What does Glycolic Acid do for mature skin?
Glycolic acid helps smooth mature skin by encouraging fresh skin renewal and supporting firmness. It may also help improve signs of photoaging and increase moisture levels over time.
What does Bromelain do for mature skin?
Bromelain helps smooth mature skin by acting as an exfoliating agent to clear away dead surface layers and improve overall texture. Studies show that proteolytic enzymes like bromelain can successfully exfoliate the skin and enhance its cosmetic characteristics with a low risk of irritation.
Where does this exfoliant go in a skincare routine for mature skin?
This exfoliant treatment goes in your evening routine once a week. You start by using it weekly, and if your skin handles it well, you can carefully use it more often.
Can I use this exfoliant with retinol, and in what order?
You can use this exfoliant in your evening routine, but it is best to avoid using it on the same nights as retinol to keep your skin calm and smooth. Use the exfoliant first on its own on designated treatment nights, and apply your retinol on alternate nights to prevent dryness and irritation.
How often should I use this exfoliant?
Start by using this exfoliant once a week in your evening routine, and if your skin handles it well with good results, you can carefully use it more often. This gentle approach helps smooth texture and soften wrinkles while keeping irritation unlikely.
Journal of Cosmetic Dermatology, 2021Journal of Cosmetic Dermatology, 2024
Can this exfoliant clog pores, cause breakouts or purging for mature skin?
This exfoliant is unlikely to clog pores or cause breakouts on mature skin, as it features ingredients that smooth texture without heavy oils that trap debris. It may cause mild purging as glycolic acid, bromelain, and papain speed up skin renewal to clear fine lines, but this temporary adjustment usually passes quickly with consistent use.
Is this exfoliant fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol. Cetyl alcohol is a fatty alcohol, which soften the skin.
What the research says
Repeated short-contact 70% glycolic acid peels provided superior results in atrophic acne scars compared to daily low-strength glycolic acid cream or placebo in 58 women over 24 weeks.
International Journal of Dermatology, 2000Serial glycolic acid peels combined with a modified Kligman formula significantly reduced facial PIH severity in Indian patients compared to the modified Kligman formula alone.
Dermatologic Surgery, 2017Oral bromelain slightly reduced pain compared to controls (mean difference -0.27) and topical bromelain reduced time to complete debridement by 6.89 days, with no major health risks reported.
Nutrition and Health, 2023An upcycled pineapple leaf fibre crosspolymer forms a physical barrier that protects against environmental aggressors while providing antioxidant, anti-inflammatory, antipollution, UV protection, hydration, and hair benefits.
International Journal of Cosmetic Science, 2026A coaxial electrospun core-shell nanofiber scaffold delivering bromelain and salvianolic acid B demonstrated sustained drug release, in vitro endothelial cell migration, increased capillary formation in an in ovo assay, and in vivo efficacy for skin regeneration and wound healing.
Biomedical Materials, 2017Topical papain treatment may slightly decrease pain within 30 minutes in humans stung by Chrysaora chinensis compared to placebo.
Wilderness & Environmental Medicine, 2016A fixed combination of hydroxypinacolone retinoate, retinol glycospheres, and papain glycospheres in aqueous gel applied once daily for 12 weeks achieved a 41% mean reduction in GAGS score and a 40.8% mean reduction in total lesions, with 15.3% of patients experiencing mild to moderate local side effects, in 94 evaluable patients with comedonal-papular, mild to moderate acne of the face.
Giornale Italiano Di Dermatologia E Venereologia, 2015Reflux extraction of Carica papaya leaves yielded higher antioxidant capacity and superior in vitro wound-healing activities including fibroblast proliferation, cell migration, and collagen synthesis in human skin fibroblasts compared to ultrasonic-assisted extraction and agitation.
Molecules, 2020Topical sulforaphane treatment reduced mottled skin pigmentation in humans and UV-induced pigmentation in wild-type mice through NRF2 and keratinocyte-specific IL-6Rα signaling.
JCI Insight, 2020Topical application of sulforaphane-rich broccoli sprout extracts reduced UVR-induced erythema by a mean of 37.7% in six human subjects.
Proceedings of the National Academy of Sciences of the United States of America, 2007Pre-treatment with sulforaphane and phenylethyl isothiocyanate significantly counteracted UVR-induced increases in apoptosis and decreases in catalase in human skin by inducing Nrf2-dependent antioxidant pathways.
Pharmacological Research, 2013
Ingredients
Water, Cyclopentasiloxane, Glycolic Acid, Dimethicone, Methylheptyl Isostearate, Cetyl Alcohol, Diglycerin, Dimethicone Crosspolymer, Glyceryl Stearate, Peg-100 Stearate, Isohexadecane, Helianthus Annuus Seed Oil Sunflower Seed Oil, Dimethiconol, Carthamus Tinctorius Seed Oil, Maltodextrin, Aleurites Moluccana Seed Oil, Brassica Oleracea Italica Extract, Oleth-20, Bromelain, Algin, Tocopherol, Papain, Xanthan Gum, Carbomer, Disodium Edta, Caprylyl Glycol, 1,2-Hexanediol, Ascorbyl Palmitate, Sodium Hydroxide, Phenoxyethanol, Chlorphenesin
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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