# Vichy LiftActiv Vitamin C Serum for mature skin

**Lovi Fit: Average fit for mature skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/nl/p/vichy/liftactiv-vitamin-c-serum/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Brand: [Vichy](https://lovi.care/skincare/nl/brands/vichy)
Category: [Serums and treatments](https://lovi.care/skincare/nl/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for mature skin; other serums fit it better.

## Why this fit

- Offers moderate benefits for your normal skin, as ascorbic acid and tocopherol provide antioxidant activity and support collagen synthesis, though it does not specifically target your wrinkles and fine lines.
- Hydrolyzed hyaluronic acid offers general hydration, which is supportive for your skin, but not a primary treatment for your main concerns.
- The product is safe for your normal skin due to the absence of harsh ingredients, minimizing irritation risks.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/nl/p/vichy/liftactiv-vitamin-c-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/nl/p/vichy/liftactiv-vitamin-c-serum/for/dry-skin): Caution
- [Combination skin](https://lovi.care/skincare/nl/p/vichy/liftactiv-vitamin-c-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/nl/p/vichy/liftactiv-vitamin-c-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/nl/p/vichy/liftactiv-vitamin-c-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/nl/p/vichy/liftactiv-vitamin-c-serum/for/dark-spots): Low
- [Mature skin](https://lovi.care/skincare/nl/p/vichy/liftactiv-vitamin-c-serum/for/mature-skin): Average (this page)
- [Dry sensitive skin](https://lovi.care/skincare/nl/p/vichy/liftactiv-vitamin-c-serum/for/dry-sensitive-skin): Caution
- [Oily acne-prone skin](https://lovi.care/skincare/nl/p/vichy/liftactiv-vitamin-c-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Ascorbic Acid, Hydrolyzed Hyaluronic Acid, Neohesperidin Dihydrochalcone, Tocopherol Vitamin E, Pinus Pinaster Bud Extract Bark

## What the research says

- Profhilo treatment led to significant improvements in superficial skin hydration and transepidermal water loss over time in Chinese females, while demonstrating good product tolerability. ([Aesthetic Plastic Surgery, 2026](https://pubmed.ncbi.nlm.nih.gov/40921777/))
- Profhilo gel combined with Dysport Botox significantly improved skin hydration, skin thickness, and GAIS scores compared to Dysport Botox injection alone in 19 participants seeking neck rejuvenation. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/35775872/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40642809/))
- Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate. ([Contemporary Clinical Trials Communications, 2021](https://pubmed.ncbi.nlm.nih.gov/34471722/))
- Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590207/))
- A topical antioxidant serum significantly reduced air pollution-induced skin pigmentation and proinflammatory gene expression ex vivo, and improved skin aging signs in 40 healthy adult females after 90 days of daily use. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35150043/))
- A xanthan gum and alginate-based bioadhesive film loaded with pycnogenol provides sustained drug release within 24 hours, achieves a safe maximum concentration of ~ 0.2 mg/mL for keratinocytes, and absorbs simulated wound fluid, demonstrating suitability for topical wound treatment. ([Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33802607/))
- Topical treatment with Pinus brutia bark extract cream significantly accelerated incision wound healing in albino rats, demonstrating a 35% decrease in MDA and a 46.8% increase in SOD activity compared to the control group. ([Die Pharmazie, 2013](https://pubmed.ncbi.nlm.nih.gov/23444785/))

## Why other serums fit mature skin better

- Caviar oil enhanced adipocyte differentiation in vitro, reduced MMP expression while increasing collagen and elastin formation ex vivo, and improved skin moisture, elasticity, and density in 102 participants over four weeks of Cavi Balm usage compared to baseline. ([In Vivo, 2023](https://pubmed.ncbi.nlm.nih.gov/37652485/))
- Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/))

## What reviewers say

Based on a very large amount of data, users report this serum effectively brightens dull complexions and evens skin tone, with many seeing radiance within weeks. Its lightweight, fast-absorbing texture is often appreciated, even by those with sensitive skin. Some users note a sticky finish, and a smaller number experience issues with the product oxidizing or an unpleasant smell.

- Liked: Brightens complexion (mostly mentioned)
- Liked: Evens skin tone (often mentioned)
- Liked: Smoother texture (often mentioned)
- Liked: Fast absorption (sometimes noted)
- Liked: Gentle on skin (sometimes noted)
- Disliked: Sticky finish (sometimes noted)
- Disliked: Oxidation issues (rarely noted)
- Disliked: Packaging flaws (rarely noted)
- Disliked: Skin irritation (rarely noted)
- Disliked: Unpleasant smell (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Vichy LiftActiv Vitamin C work for mature skin?

This serum works moderately well for mature skin, as it provides antioxidants and general hydration to keep skin healthy, but it does not specifically target deeper wrinkles and fine lines. A treatment of this type needs high concentrations of potent antioxidants, peptides, and skin-repairing ingredients that target wrinkles and improve firmness and elasticity for mature skin.
Sources: [Aesthetic Plastic Surgery, 2026](https://pubmed.ncbi.nlm.nih.gov/40921777/)

### Which ingredients make this serum a good fit for mature skin?

Ascorbic acid and tocopherol make this serum a good fit for mature skin because they provide antioxidant activity and support collagen synthesis, while hydrolyzed hyaluronic acid offers general hydration. However, a product for this skin type needs high-quality anti-aging ingredients that specifically target wrinkles and fine lines, along with potent antioxidants, peptides, and skin-repairing components for optimal results.
Sources: [Aesthetic Plastic Surgery, 2026](https://pubmed.ncbi.nlm.nih.gov/40921777/)

### What does Vitamin C do for mature skin?

Vitamin C helps mature skin by smoothing out wrinkles, brightening dark spots, and boosting firmness. It works by encouraging collagen production to keep skin looking youthful and radiant.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/), [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37128827/)

### What does Hydrolyzed Hyaluronic Acid do for mature skin?

Hydrolyzed hyaluronic acid helps mature skin by significantly boosting skin hydration, improving elasticity, and reducing the look of deep wrinkles. It is unlikely to cause irritation, making it a well-suited choice for keeping dry and aging skin looking smooth.
Sources: [Colloids and Surfaces. B, Biointerfaces, 2022](https://pubmed.ncbi.nlm.nih.gov/36279763/)

### Where does this serum go in a skincare routine for mature skin?

This serum goes in the evening routine for mature skin. A vitamin C antioxidant serum like this helps improve overall skin clarity and brightness when used as part of a regular daily skincare regimen.
Sources: [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36607762/)

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the vitamin C serum in the morning and your retinol at night to avoid overwhelming your skin. Using them at different times of day helps reduce the likelihood of irritation while still giving you the antioxidant and firming benefits.

### How often should I use this serum?

You can use this treatment in the evening as part of your routine. A product of this type for mature skin needs ingredients like retinoids and targeted anti-aging peptides to visibly smooth lines and wrinkles.

### Can this serum clog pores, cause breakouts or purging for mature skin?

This serum is unlikely to clog pores or cause breakouts for mature skin due to the absence of heavy oils and harsh ingredients. A product of this type needs antioxidants like ascorbic acid and tocopherol, along with hydrating ingredients such as hydrolyzed hyaluronic acid, to keep your skin smooth and protected without causing blemishes.

### Is this serum fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (alcohol denat).

## Alternatives for mature skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/nl/p/skinceuticals/c-e-ferulic/for/mature-skin) — Superior fit — €160.00 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/nl/p/neogen-dermalogy/real-vita-c-serum/for/mature-skin) — High fit — €35.50 at Amazon
- [La Mer The Regenerating Serum](https://lovi.care/skincare/nl/p/la-mer/the-regenerating-serum/for/mature-skin) — High fit — €419.00 at Amazon

## Pairs well with

- Cleanser: [d'Alba White Truffle Return Oil Cream Cleanser](https://lovi.care/skincare/nl/p/d-alba/white-truffle-return-oil-cream-cleanser/for/mature-skin) — Superior fit — €25.07 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/nl/p/some-by-mi/snail-truecica-miracle-repair-toner/for/mature-skin) — Superior fit — €19.90 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/nl/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/mature-skin) — Superior fit — €48.84 at Amazon

## Where to buy

- Lookfantastic: €36.66 (https://www.lookfantastic.nl/p/vichy-liftactiv-supreme-16-pure-vitamin-c-brightening-serum-20ml/13494902/)
Prices checked 10 Oct 2026.

## Ingredients

Water, Ascorbic Acid, Alcohol Denat, Dipropylene Glycol, Glycerin, Laureth-23, Neohesperidin Dihydrochalcone, Sodium Hydroxide, Tocopherol, Hydrolyzed Hyaluronic Acid, Pinus Pinaster Bud Extract Bark
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/vichy/liftactiv-vitamin-c-serum/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/vichy/liftactiv-vitamin-c-serum/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/vichy/liftactiv-vitamin-c-serum/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/vichy/liftactiv-vitamin-c-serum/for/mature-skin
- France: https://lovi.care/skincare/fr/p/vichy/liftactiv-vitamin-c-serum/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/vichy/liftactiv-vitamin-c-serum/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/vichy/liftactiv-vitamin-c-serum/for/mature-skin (this page)
- Spain: https://lovi.care/skincare/es/p/vichy/liftactiv-vitamin-c-serum/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/vichy/liftactiv-vitamin-c-serum/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/vichy/liftactiv-vitamin-c-serum/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/vichy/liftactiv-vitamin-c-serum/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/vichy/liftactiv-vitamin-c-serum/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/vichy/liftactiv-vitamin-c-serum/for/mature-skin