# Vichy Liftactiv Specialist B3 Serum for oily acne-prone skin

**Lovi Fit: High fit for oily acne-prone skin.**
Oily Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/nl/p/vichy/liftactiv-specialist-b3-serum/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Brand: [Vichy](https://lovi.care/skincare/nl/brands/vichy)
Category: [Serums and treatments](https://lovi.care/skincare/nl/best/serums)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for oily acne-prone skin; a few serums fit it even better.

## Why this fit

- Highly suitable for your oily skin, this serum leverages niacinamide and glycolic acid to effectively regulate oil production and refine skin texture, addressing your concerns with acne, blemishes, and breakouts.
- The inclusion of tranexamic acid and allantoin further supports skin tone evening and provides a soothing effect, enhancing the overall benefits for your skin.
- The safety profile is excellent, with no risks of irritation for your oily skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/nl/p/vichy/liftactiv-specialist-b3-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/nl/p/vichy/liftactiv-specialist-b3-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/nl/p/vichy/liftactiv-specialist-b3-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/nl/p/vichy/liftactiv-specialist-b3-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/nl/p/vichy/liftactiv-specialist-b3-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/nl/p/vichy/liftactiv-specialist-b3-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/nl/p/vichy/liftactiv-specialist-b3-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/nl/p/vichy/liftactiv-specialist-b3-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/nl/p/vichy/liftactiv-specialist-b3-serum/for/oily-acne-prone-skin): High (this page)

## Key ingredients

Niacinamide, Glycolic Acid, Tranexamic Acid, Ascorbyl Glucoside, Hydrolyzed Rice Protein

## What the research says

- Glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene showed no hindrance compared to adapalene monotherapy and provided benefits in reducing complications in 25 subjects with mild-to-moderate acne vulgaris. ([Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30858720/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Repeated short-contact 70% glycolic acid peels provided superior results in atrophic acne scars compared to daily low-strength glycolic acid cream or placebo in 58 women over 24 weeks. ([International Journal of Dermatology, 2000](https://pubmed.ncbi.nlm.nih.gov/11095203/))
- Serial glycolic acid peels combined with a modified Kligman formula significantly reduced facial PIH severity in Indian patients compared to the modified Kligman formula alone. ([Dermatologic Surgery, 2017](https://pubmed.ncbi.nlm.nih.gov/28114204/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Rice protein hydrolysate and its characteristic peptides Leu-Leu-Lys, Leu-Pro-Lys, and pyroGlu-Lys reduced melanin content, tyrosinase activity, and ROS production in UVB-induced human epidermal melanocyte PIG1 cells by regulating the JNK/Β-Trcp/NFΗB-p65/MITF signaling pathway and lowering TRP-1 and TRP-2 expression. ([Food & Function, 2020](https://pubmed.ncbi.nlm.nih.gov/32955075/))

## What reviewers say

Based on a very large amount of data, this serum is highly praised by users dealing with hyperpigmentation, dullness, and uneven skin tone for its ability to visibly fade dark spots and brighten the complexion. Its lightweight, fast-absorbing formula is frequently noted as gentle on sensitive skin. Some users indicate that consistent, long-term use is necessary to see significant results on stubborn dark spots and deep wrinkles.

- Liked: Evens skin tone (often mentioned)
- Liked: Fades dark spots (often mentioned)
- Liked: Lightweight and fast-absorbing (often mentioned)
- Liked: Gentle on sensitive skin (sometimes noted)
- Disliked: Takes time for results (sometimes noted)
- Disliked: Applicator design issues (rarely noted)
- Disliked: Ineffective on deep wrinkles (rarely noted)

## How to apply

- Could be used as part of your PM routine. Start 3 times a week and build up to daily use if your skin tolerates it well.
- Apply your serum after cleansing and toning, but before putting on your moisturizer.
- Gently press 2 to 3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on clean, dry skin to help manage your blemishes safely.
- Do a patch test before your first use and avoid the delicate eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Liftactiv B3 Serum a great fit for oily acne-prone skin?

Vichy Liftactiv Specialist B3 Serum is a great fit because it uses niacinamide and glycolic acid to control oil and smooth your skin while helping with acne and breakouts. Tranexamic acid and allantoin also help even out your skin tone and keep it calm. It is very safe for this skin type and is unlikely to cause irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30858720/), [Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/)

### Which ingredients make this serum a good fit for oily acne-prone skin?

Niacinamide and glycolic acid make this serum a great fit because they help regulate oil production and refine texture to tackle breakouts. Tranexamic acid and allantoin also support an even skin tone and calm the skin.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30858720/), [Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/)

### What does Niacinamide do for oily acne-prone skin?

Niacinamide helps balance oil production, calms redness, and is unlikely to irritate oily, acne-prone skin while improving blemishes. Clinical tests show it reduces excess oil and helps clear up both inflammatory and non-inflammatory acne breakouts.
Sources: [Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38299457/)

### What does Glycolic Acid do for oily acne-prone skin?

Glycolic acid helps clear acne-prone skin by reducing pimples and soothing breakouts. It exfoliates the surface to keep pores clear and leaves the skin feeling smooth.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30858720/), [Dermatologic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24447110/)

### Where does this serum go in a skincare routine for oily acne-prone skin?

This treatment serum goes in the evening routine after cleansing and before moisturizing. Lovi routines put treatments in the evening for simplicity and extra safety around sun exposure, though some can also be used in the morning or twice a day.

### Can I use this serum with retinol, and in what order?

You can use this treatment alongside retinol by applying the serum first in your evening routine, allowing it to absorb fully before putting on your retinol. This serum is unlikely to cause irritation for your oily skin because it lacks harsh ingredients, but using both active products together may still cause some dryness or sensitivity if you are not careful. Try starting slowly, perhaps alternating nights or using the serum in the morning and retinol at night, to see how your skin feels.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/)

### How often should I use this serum?

Start by using this treatment once a week in the evening, and if your skin feels comfortable and results look good, you can carefully use it more often. It is unlikely to cause irritation for your oily skin because it avoids harsh ingredients.

### Can this serum clog pores, cause breakouts or purging for oily acne-prone skin?

This serum is unlikely to clog pores or cause breakouts for oily acne-prone skin, as it contains no harsh ingredients and is very safe for your skin type. Niacinamide and glycolic acid help control oil and smooth texture, while allantoin and tranexamic acid help calm the skin.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30858720/), [Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily acne-prone skin

- [Clinique Fresh Pressed Daily Booster with Pure Vitamin C 10%](https://lovi.care/skincare/nl/p/clinique/fresh-pressed-daily-booster-with-pure-vitamin-c-10/for/oily-acne-prone-skin) — Superior fit — €99.41 at Amazon
- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/nl/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/oily-acne-prone-skin) — Superior fit — €10.20 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/nl/p/neogen-dermalogy/real-vitamin-c-serum/for/oily-acne-prone-skin) — Superior fit — €35.50 at Amazon

## Pairs well with

- Cleanser: [Paula's Choice CLEAR Pore Normalizing Cleanser](https://lovi.care/skincare/nl/p/paula-s-choice/clear-pore-normalizing-cleanser/for/oily-acne-prone-skin) — Superior fit — €29.00 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/nl/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — €36.00 at Amazon
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/nl/p/skin1004/centella-cream/for/oily-acne-prone-skin) — Superior fit — €19.20 at Amazon

## Where to buy

- Amazon.nl: €42.95 (https://www.amazon.nl/dp/B09WF84L17?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: €49.45 (https://www.lookfantastic.nl/p/vichy-liftactiv-specialist-b3-5-niacinamide-aha-complex-dark-spots-pigmentation-serum-30ml/13441814/)
Prices checked 17 Oct – 5 Nov 2026.

## Ingredients

Water, Butylene Glycol, Niacinamide, Hydroxyethylpiperazine Ethane Sulfonic Acid, Glycerin, Hydroxyethyl Urea, Propylene Glycol, Glycolic Acid, Tranexamic Acid, Allantoin, Sodium Hydroxide, Phenoxyethanol, Chlorphenesin, Ascorbyl Glucoside, Caprylyl Glycol, Hydrolyzed Rice Protein, Vitreoscilla Ferment, Trisodium Ethylenediamine Disuccinate, Xanthan Gum, Pentylene Glycol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/vichy/liftactiv-specialist-b3-serum/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/vichy/liftactiv-specialist-b3-serum/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/vichy/liftactiv-specialist-b3-serum/for/oily-acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/vichy/liftactiv-specialist-b3-serum/for/oily-acne-prone-skin
- France: https://lovi.care/skincare/fr/p/vichy/liftactiv-specialist-b3-serum/for/oily-acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/vichy/liftactiv-specialist-b3-serum/for/oily-acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/vichy/liftactiv-specialist-b3-serum/for/oily-acne-prone-skin (this page)
- Spain: https://lovi.care/skincare/es/p/vichy/liftactiv-specialist-b3-serum/for/oily-acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/vichy/liftactiv-specialist-b3-serum/for/oily-acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/vichy/liftactiv-specialist-b3-serum/for/oily-acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/vichy/liftactiv-specialist-b3-serum/for/oily-acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/vichy/liftactiv-specialist-b3-serum/for/oily-acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/vichy/liftactiv-specialist-b3-serum/for/oily-acne-prone-skin