Too Faced Hangover Pillow Cream for mature skin

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Questions and answers

What the research says

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group.

  American Journal of Clinical Dermatology, 2013

• Treatment with a combination of niacinamide and hyaluronic acid improved skin aging signs and demonstrated a senomorphic effect by decreasing SASP and autocrine signaling genes in women.

  Scientific Reports, 2024

• Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone.

  Dermatologic Therapy, 2022

• Argireline applied twice daily for 4 weeks achieved a total anti-wrinkle efficiency of 48.9% and notably reduced wrinkle depth compared to placebo in Chinese subjects.

  Journal of Cosmetic and Laser Therapy, 2013

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events.

  Lasers in Medical Science, 2025

• A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells.

  International Journal of Cosmetic Science, 2025

• Overnight virgin coconut oil application provides a skin protective effect against damage and increased TEWL from frequent alcohol-based hand sanitizer usage in 60 volunteers, resulting in a 25% increase in perceived moisture content compared to the control group.

  Journal of Cosmetic Dermatology, 2021

• Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.

  Journal of Cosmetic Dermatology, 2021

• Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.

  The Journal of Investigative Dermatology, 2008

• Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.

  Dermatologic Surgery, 2005

Ingredients

Water, Dimethicone, Petrolatum, Glycerin, Caprylic Capric Myristic Stearic Triglyceride, Isopropyl Isostearate, Glycereth-26, Butylene Glycol, Peg-100 Stearate, Niacinamide, Squalane, Hydroxyethyl Urea, Rice Bran Oil, Polysilicone-11, Cetearyl Alcohol, Sodium Polyaspartate, Meteorite Powder, Lactobacillus Ferment, Yogurt Powder, Tocopheryl Acetate, Sodium Hyaluronate, Caffeine, Coconut Oil, Coconut Liquid Endosperm, Coconut Fruit Juice, Butyrospermum Parkii Butter Shea Butter, Laminaria Digitata Extract, Olea Europaea Oil Fruit Olive Oil Fruit, Mangifera Indica Seed Butter, Persea Gratissima Oil Avocado Oil, Punica Granatum Sterols, Sigesbeckia Orientalis Extract, Porphyridium Cruentum Extract, Palmitoyl Hexapeptide-12, Acetyl Hexapeptide-8, Linoleic Acid, Caprylic Capric Triglyceride, Trehalose, Cetearyl Glucoside, Sorbitol, Myristyl Myristate, Isohexadecane, Aluminum Hydroxide, Tin Oxide, Tromethamine, Peg-8, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Polysorbate 80, Sucrose, Silica, Glyceryl Polymethacrylate, Acrylamide Sodium Acryloyldimethyltaurate Copolymer, Synthetic Fluorphlogopite, Caprylyl Glycol, Citric Acid, Stearic Acid, Glyceryl Stearate, Myristyl Alcohol, Hydrogenated Oil, Parfum, Tocopherol, Disodium Edta, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Bht, Potassium Sorbate, Phenoxyethanol, Mica, Titanium Dioxide Ci 77891, Red 4 Ci 14700

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.