# SkinCeuticals Silymarin CF for oily skin

**Lovi Fit: Superior fit for oily skin.**
Oily Skin Fit: Superior · Effectiveness: Superior · Safety: Excellent.

Page: https://lovi.care/skincare/nl/p/skinceuticals/silymarin-cf/for/oily-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Brand: [SkinCeuticals](https://lovi.care/skincare/nl/brands/skinceuticals)
Category: [Serums and treatments](https://lovi.care/skincare/nl/best/serums)

This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best serums for oily skin.

## Why this fit

- Excellent suitability for your oily skin is provided by salicylic acid and ferulic acid, which offer keratolytic action and antioxidant activity respectively, ideal for managing excess sebum and providing optimal benefits.
- The formulation also offers excellent treatment for oily and acne-prone skin due to the presence of salicylic acid and silymarin for pore decongestion and antioxidant protection in high concentrations.
- There are no risks of irritation for your oily skin due to the absence of prohibited or harsh ingredients, and the presence of soothing ingredients like Silybum Marianum Fruit Extract.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/nl/p/skinceuticals/silymarin-cf/for/oily-skin): Superior (this page)
- [Dry skin](https://lovi.care/skincare/nl/p/skinceuticals/silymarin-cf/for/dry-skin): Caution
- [Combination skin](https://lovi.care/skincare/nl/p/skinceuticals/silymarin-cf/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/nl/p/skinceuticals/silymarin-cf/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/nl/p/skinceuticals/silymarin-cf/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/nl/p/skinceuticals/silymarin-cf/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/nl/p/skinceuticals/silymarin-cf/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/nl/p/skinceuticals/silymarin-cf/for/dry-sensitive-skin): Caution
- [Oily acne-prone skin](https://lovi.care/skincare/nl/p/skinceuticals/silymarin-cf/for/oily-acne-prone-skin): High

## Key ingredients

Silymarin, Ascorbic Acid, Ferulic Acid, Salicylic Acid

## What the research says

- A moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid significantly reduced noninflammatory, inflammatory, and total acne lesion counts compared to a vehicle control in Thai patients during a 12-week maintenance phase. ([BioMed Research International, 2020](https://pubmed.ncbi.nlm.nih.gov/33150170/))
- Twice daily application of a multitargeted dermocosmetic cream provided comparable efficacy to benzoyl peroxide 5% gel in reducing inflammatory, non-inflammatory, and total lesions in 150 Caucasian subjects with mild-to-moderate acne over 56 days, while demonstrating superior skin tolerability. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/))
- The use of a salicylic acid-based dermocosmetic significantly reduces the needed quantity of benzoyl peroxide without impacting efficacy in mild to moderate acne, and as maintenance post-benzoyl peroxide allows a significant reduction of acne relapse compared to vehicle. ([Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/38051857/))
- Topical 0.5% silymarin-loaded antioxidant serum applied twice daily significantly reduced clinical acne severity, lesion counts, and melanin pigmentation in 22 Korean acne patients over 4 weeks without associated adverse events. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36204969/))
- Topical silymarin cream 1.4% showed comparable results to salicylic acid 30% peels in reducing acne severity in 30 patients with mild to moderate acne vulgaris. ([Journal of Cutaneous Medicine and Surgery, 2024](https://pubmed.ncbi.nlm.nih.gov/37942562/))
- Silymarin antioxidant serum reduced inflammatory lesions by 45% and noninflammatory lesions by 43% in 56 subjects over 12 weeks, and improved tolerability by reducing erythema, dryness, and scaling when added to prescription acne therapy in 40 subjects. ([Journal of Drugs in Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38564394/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Treatment with 14% ferulic acid and 12% l-ascorbic acid significantly reduced pigmentation and erythema while improving hydration and elasticity in 20 women with photoaged skin, with neither acid proving definitively more effective overall though ascorbic acid showed slightly greater skin lightening. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/34877760/))
- Combining fractional microneedle radiofrequency with a topical antioxidant serum significantly reduced wrinkle severity by 29.9% versus 18.0%, increased elasticity by 12.9% versus 2.3%, and improved aesthetic outcomes in 31 participants compared to radiofrequency and placebo. ([The Journal of Dermatological Treatment, 2025](https://pubmed.ncbi.nlm.nih.gov/40464749/))
- Pretreatment with a topical antioxidant mixture of vitamin C, ferulic acid, and phloretin attenuated ultraviolet-induced sunburn cell formation, thymine dimer formation, matrix metalloproteinase-9 expression, p53 protein expression, and the suppression of CD1a-expressing Langerhans cells in human skin compared to vehicle control. ([Journal of Cosmetic Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19146606/))
- Cryotherapy with liquid nitrogen achieved a higher cure rate (39%) than salicylic acid (24%) and a wait-and-see approach (16%) for cutaneous warts at 13 weeks in primary care patients. ([CMAJ, 2010](https://pubmed.ncbi.nlm.nih.gov/20837684/))
- Treatment with 2% supramolecular salicylic acid hydrogel resulted in a regression and markedly improvement rate of 51.01% compared to 43.10% for Adapaline gel in patients with mild to moderate facial acne vulgaris, showing no significant difference in efficacy. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590107/))
- Topical 5% benzoyl peroxide plus salicylic acid achieved the greatest lesion reduction at early 2 to 4 week time points compared to benzoyl peroxide, clindamycin, and combination benzoyl peroxide/clindamycin, while 5% benzoyl peroxide plus salicylic acid and combination benzoyl peroxide/clindamycin showed similar efficacy at 10 to 12 weeks in acne patients. ([Journal of the American Academy of Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20488582/))

## What reviewers say

Users with oily and acne-prone skin frequently describe this serum as a "game-changer" that significantly reduces excess sebum and prevents breakouts. Many reviewers report visible improvements in skin texture and clarity, noting a reduction in pore size and a smoother, more radiant complexion after consistent use.

- Liked: Effective for oily/acne (mostly mentioned)
- Liked: Improves texture/clarity (often mentioned)
- Disliked: High price point (often mentioned)
- Disliked: Unpleasant smell (often mentioned)
- Liked: Lightweight and fast-absorbing (sometimes noted)
- Liked: Prevents breakouts (sometimes noted)
- Disliked: Caused irritation (rarely noted)
- Disliked: Sticky finish (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week and build up to daily use if your skin tolerates it well.
- Apply the serum after cleansing and toning, but right before your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin. Let it absorb ⏱ for a minute before applying the next product.
- Apply the serum on clean and dry skin since your skin is not sensitive and you want to target oily shine. This helps control excess oil throughout the night.
- Avoid the delicate eye area and do a patch test before using the serum for the very first time.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes SkinCeuticals Silymarin CF one of the best fits for oily skin?

SkinCeuticals Silymarin CF is one of the best fits for your oily skin because it uses salicylic acid and silymarin to clear out pores and manage excess oil. It also includes ferulic acid and silymarin extract to provide antioxidant protection while keeping your skin calm and comfortable.
Sources: [BioMed Research International, 2020](https://pubmed.ncbi.nlm.nih.gov/33150170/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/)

### Which ingredients make this serum a good fit for oily skin?

Salicylic acid and silymarin make this serum a great fit by clearing out pores and managing excess oil, while ferulic acid provides antioxidant protection. Soothing plant extract helps keep the skin calm and comfortable without irritation.
Sources: [BioMed Research International, 2020](https://pubmed.ncbi.nlm.nih.gov/33150170/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/)

### What does Silymarin do for oily skin?

Silymarin helps keep oily skin clear by reducing blemishes and breakouts while calming redness. This ingredient is well-tolerated and may improve overall skin texture without causing dryness.
Sources: [Journal of Drugs in Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38564394/)

### What does Vitamin C do for oily skin?

Vitamin C helps brighten skin tone and smooth texture while providing antioxidant protection that prevents sebum oxidation. For oily skin, this type of product typically needs to be paired with oil-controlling or pore-clearing ingredients like salicylic acid or plant extracts.
Sources: [International Journal of Cosmetic Science, 2005](https://pubmed.ncbi.nlm.nih.gov/18492184/), [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37128827/)

### Where does it go in a skincare routine for oily skin?

This treatment goes in the evening routine after cleansing and before your moisturizer. Putting it at night helps manage excess oil and unclog pores while keeping your skin safe from sun exposure.

### Can I use this serum with retinol, and in what order?

Apply this serum in your morning routine and save your retinol for the evening to help prevent skin irritation. Using them at different times of day allows the salicylic acid and vitamin C in this treatment to manage oil and protect your skin without overwhelming it.

### How often should I use it?

Apply this treatment in the evening, starting once a week to see how your skin reacts. If your skin feels comfortable and you see good results, you can carefully use it more often.

### Can it clog pores, cause breakouts or purging for oily skin?

SkinCeuticals Silymarin CF is unlikely to clog your pores or cause breakouts because it contains salicylic acid and silymarin to help clear out pores and manage excess oil. The formula has a safe design for oily skin without harsh ingredients, so irritation and purging are uncommon.
Sources: [BioMed Research International, 2020](https://pubmed.ncbi.nlm.nih.gov/33150170/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/)

### Is this serum fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (alcohol denat).

## Alternatives for oily skin

- [Clinique Fresh Pressed Daily Booster with Pure Vitamin C 10%](https://lovi.care/skincare/nl/p/clinique/fresh-pressed-daily-booster-with-pure-vitamin-c-10/for/oily-skin) — Superior fit — €99.41 at Amazon
- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/nl/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/oily-skin) — Superior fit — €10.20 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/nl/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/oily-skin) — Superior fit — €35.80 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/nl/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — €21.00 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/nl/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — €19.90 at Amazon
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/nl/p/skin1004/centella-cream/for/oily-skin) — Superior fit — €19.20 at Amazon

## Where to buy

- Amazon.nl: €182.75 (https://www.amazon.nl/dp/B08WCM8PK4?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: €165.26 (https://www.lookfantastic.nl/p/skinceuticals-silymarin-cf-vitamin-c-salicylic-acid-antioxidant-serum-30ml/12781515/)
Prices checked 10 Oct – 5 Nov 2026.

## Ingredients

Water, Alcohol Denat, Ascorbic Acid, Propylene Glycol, Dipropylene Glycol, Laureth-23, Silybum Marianum Fruit Extract, Sodium Citrate, Salicylic Acid, Ferulic Acid
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/skinceuticals/silymarin-cf/for/oily-skin
- United Kingdom: https://lovi.care/skincare/uk/p/skinceuticals/silymarin-cf/for/oily-skin
- Ireland: https://lovi.care/skincare/ie/p/skinceuticals/silymarin-cf/for/oily-skin
- Germany: https://lovi.care/skincare/de/p/skinceuticals/silymarin-cf/for/oily-skin
- France: https://lovi.care/skincare/fr/p/skinceuticals/silymarin-cf/for/oily-skin
- Italy: https://lovi.care/skincare/it/p/skinceuticals/silymarin-cf/for/oily-skin
- Netherlands: https://lovi.care/skincare/nl/p/skinceuticals/silymarin-cf/for/oily-skin (this page)
- Spain: https://lovi.care/skincare/es/p/skinceuticals/silymarin-cf/for/oily-skin
- Canada: https://lovi.care/skincare/ca/p/skinceuticals/silymarin-cf/for/oily-skin
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- United Arab Emirates: https://lovi.care/skincare/ae/p/skinceuticals/silymarin-cf/for/oily-skin