# SkinCeuticals Glycolic 10 Renew Overnight for mature skin

**Lovi Fit: Average fit for mature skin.**
Normal Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/nl/p/skinceuticals/glycolic-10-renew-overnight/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Brand: [SkinCeuticals](https://lovi.care/skincare/nl/brands/skinceuticals)
Category: [Exfoliants](https://lovi.care/skincare/nl/best/exfoliators)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for mature skin; other products fit it better.

## Why this fit

- Offers moderate exfoliation for your normal skin due to glycolic acid and phytic acid, which promote skin renewal and texture smoothing, but these ingredients are not specialized enough to significantly address your primary concerns of wrinkles and fine lines.
- While the formula provides general skincare benefits and is suitable for normal skin, it lacks sufficient humectant and emollient ingredients for optimal hydration and barrier support.
- The product is safe for your normal skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/nl/p/skinceuticals/glycolic-10-renew-overnight/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/nl/p/skinceuticals/glycolic-10-renew-overnight/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/nl/p/skinceuticals/glycolic-10-renew-overnight/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/nl/p/skinceuticals/glycolic-10-renew-overnight/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/nl/p/skinceuticals/glycolic-10-renew-overnight/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/nl/p/skinceuticals/glycolic-10-renew-overnight/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/nl/p/skinceuticals/glycolic-10-renew-overnight/for/mature-skin): Average (this page)
- [Dry sensitive skin](https://lovi.care/skincare/nl/p/skinceuticals/glycolic-10-renew-overnight/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/nl/p/skinceuticals/glycolic-10-renew-overnight/for/oily-acne-prone-skin): High

## Key ingredients

Glycolic Acid, Phytic Acid, Salicylic Acid, Glycerin, Dimethicone

## What the research says

- Repeated short-contact 70% glycolic acid peels provided superior results in atrophic acne scars compared to daily low-strength glycolic acid cream or placebo in 58 women over 24 weeks. ([International Journal of Dermatology, 2000](https://pubmed.ncbi.nlm.nih.gov/11095203/))
- Serial glycolic acid peels combined with a modified Kligman formula significantly reduced facial PIH severity in Indian patients compared to the modified Kligman formula alone. ([Dermatologic Surgery, 2017](https://pubmed.ncbi.nlm.nih.gov/28114204/))
- L-ascorbic acid 10% plus phytic acid 2% serum significantly reduced the pigmentation index of solar lentigines compared to a vehicle control in 30 healthy subjects. ([Journal of Cosmetic Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22151934/))
- Chemical peels using 35% glycolic acid, 20% salicylic-10% mandelic acid, and phytic acid reduce acne scores by 70.55%, 74.14%, and 69.7% respectively, and significantly decline the postacne hyperpigmentation index in Asian patients with mild to moderate acne. ([Journal of Cutaneous and Aesthetic Surgery, 2019](https://pubmed.ncbi.nlm.nih.gov/31619887/))
- A topical facial emulsion containing 10% glycolic acid, 2% phytic acid, and a soothing complex significantly improved skin hyperpigmentation, texture, and tone homogeneity from week 4 through week 12 in American female volunteers with Fitzpatrick skin types II-VI. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33458927/))
- Cryotherapy with liquid nitrogen achieved a higher cure rate (39%) than salicylic acid (24%) and a wait-and-see approach (16%) for cutaneous warts at 13 weeks in primary care patients. ([CMAJ, 2010](https://pubmed.ncbi.nlm.nih.gov/20837684/))
- A moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid significantly reduced noninflammatory, inflammatory, and total acne lesion counts compared to a vehicle control in Thai patients during a 12-week maintenance phase. ([BioMed Research International, 2020](https://pubmed.ncbi.nlm.nih.gov/33150170/))
- Treatment with 2% supramolecular salicylic acid hydrogel resulted in a regression and markedly improvement rate of 51.01% compared to 43.10% for Adapaline gel in patients with mild to moderate facial acne vulgaris, showing no significant difference in efficacy. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590107/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Wearing an N95 mask alone compared to using dimethicone cream or hydrocolloid dressing caused more adverse skin reactions among 73 military health care workers, with no significant differences in fit test failure rates between groups. ([Military Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38771104/))
- A dimethicone skin protectant lotion significantly decreased visual scoring and transepidermal water loss compared to vehicle control and SLS-only treated sites in 12 healthy humans exposed to sodium lauryl sulfate. ([Skin Research and Technology, 2000](https://pubmed.ncbi.nlm.nih.gov/11428946/))
- Treatment with a moisturizer containing dimethicone and glycerine increased epidermal thickness by 0.019 mm, improved barrier function by decreasing transepidermal water loss by 13%, decreased melanin intensity, and induced keratins 6 and 16 in fifteen women with moderately photoaged forearms. ([Clinical and Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17137484/))

## Why other products fit mature skin better

- Topical application of retinol and retinoic acid both increased epidermal thickness and upregulated collagen genes and proteins in human skin, with retinol producing similar histological and molecular changes to retinoic acid alongside a significant reduction in facial wrinkles after 12 weeks. ([Journal of Cosmetic Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/26578346/))
- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))

## What reviewers say

Based on a very large amount of data, this nighttime glycolic acid treatment is widely praised for delivering a radiant glow and significantly smoothing skin texture. It is also frequently noted for helping to clear acne and minimize pores. However, a significant number of recent reviews indicate a disappointing change in formula, resulting in a watery consistency that makes application difficult and can lead to waste.

- Liked: Noticeable glow (mostly mentioned)
- Liked: Smoother texture (often mentioned)
- Disliked: Watery consistency (often mentioned)
- Liked: Acne and pores (sometimes noted)
- Liked: Gentle exfoliation (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Dispensing issues (rarely noted)
- Disliked: Initial irritation (rarely noted)

## How to apply

- Use this exfoliant product in your PM routine once a week to start, increasing frequency only if your skin tolerates it well. Always apply SPF the next morning to protect your skin.
- Apply this exfoliant product after cleansing and toner, but before your moisturizer. This ensures the best absorption into your skin.
- Gently press 2-3 drops of the exfoliant product into your face, avoiding any rubbing. Let it absorb for a minute before moving to the next step.
- Apply this exfoliant product on completely dry skin to get the best results. This helps your normal skin accept the product smoothly.
- Avoid the sensitive eye area while using this exfoliant product. Do a patch test before your first use and avoid mixing it with strong acids.
- Video: https://storage.pora.ai/028e5e793422a3b665c02ff502cf5a68.mp4

## Questions and answers

### How well does SkinCeuticals Glycolic 10 Renew Overnight work for mature skin?

SkinCeuticals Glycolic 10 Renew Overnight works moderately well for mature skin by offering gentle exfoliation and smoothing texture, but it is not specialized enough to significantly target wrinkles and fine lines. While it is safe and provides general benefits, a product for this skin needs more powerful anti-aging ingredients, along with rich hydrating and barrier-supporting components.

### Which ingredients make this exfoliant a good fit for mature skin?

Glycolic acid and phytic acid help smooth texture and renew mature skin, while salicylic acid, glycerin, and dimethicone provide additional formulation benefits. However, this treatment needs stronger anti-aging ingredients, potent antioxidants, and nourishing hydrating components to truly target lines and wrinkles.

### What does Glycolic Acid do for mature skin?

Glycolic acid helps smooth mature skin by encouraging fresh skin renewal and supporting firmness. It may also help improve signs of photoaging and increase moisture levels over time.
Sources: [Dermatologic Surgery, 1998](https://pubmed.ncbi.nlm.nih.gov/9793513/), [Acta Medica, 2016](https://pubmed.ncbi.nlm.nih.gov/27131351/)

### What does Phytic Acid do for mature skin?

Phytic acid helps smooth and brighten mature skin while keeping it moisturized and firm. It may also improve overall skin tone and reduce the look of wrinkles over time.
Sources: [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/36056802/), [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33458927/)

### Where does this exfoliant go in a skincare routine for mature skin?

This exfoliant treatment goes in your evening routine, starting at once a week so your skin can adjust. A product of this type needs specialized ingredients for wrinkles and fine lines, along with extra softening and moisture-locking ingredients for mature skin.

### Can I use this exfoliant with retinol, and in what order?

It is best to use this exfoliant on different nights than your retinol, as using both together on mature skin may cause dryness and irritation.

### How often should I use this exfoliant?

Start by using this exfoliant once a week in the evening, and if your skin feels fine and you see good results, you can carefully use it more often. This product is unlikely to irritate your skin, though mature skin also needs extra moisture and ingredients that target fine lines and wrinkles for the best results.

### Can this exfoliant clog pores, cause breakouts or purging for mature skin?

This exfoliant is unlikely to clog pores or cause breakouts on mature skin, though it may cause a bit of initial irritation. To work best for this skin, a product of this type needs richer hydrating ingredients and specialized wrinkle-smoothing support.

### Is this exfoliant fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for mature skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/nl/p/skinceuticals/c-e-ferulic/for/mature-skin) — Superior fit — €160.00 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/nl/p/neogen-dermalogy/real-vita-c-serum/for/mature-skin) — High fit — €35.50 at Amazon
- [La Mer The Regenerating Serum](https://lovi.care/skincare/nl/p/la-mer/the-regenerating-serum/for/mature-skin) — High fit — €419.00 at Amazon

## Pairs well with

- Cleanser: [d'Alba White Truffle Return Oil Cream Cleanser](https://lovi.care/skincare/nl/p/d-alba/white-truffle-return-oil-cream-cleanser/for/mature-skin) — Superior fit — €25.07 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/nl/p/some-by-mi/snail-truecica-miracle-repair-toner/for/mature-skin) — Superior fit — €19.90 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/nl/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/mature-skin) — Superior fit — €48.84 at Amazon

## Where to buy

- Amazon.nl: €99.99 (https://www.amazon.nl/dp/B07BGHFQF1?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: €104.65 (https://www.lookfantastic.nl/p/skinceuticals-glycolic-10-renew-overnight-cream-50ml/11705721/)
Prices checked 10 Oct – 6 Nov 2026.

## Ingredients

Water, Glycolic Acid, Dicaprylyl Carbonate, Dimethicone, Sodium Hydroxide, Butylene Glycol, Propanediol, Glycerin, Phytic Acid, Cetyl Peg Ppg-10 1 Dimethicone, Aluminum Octenylsuccinate Starch, Nylon-12, Polyglyceryl-4 Isostearate, Magnesium Sulfate, Jojoba Esters, Phenoxyethanol, Helianthus Annuus Sunflower Wax Seed Cera, Caprylyl Glycol, Disodium Edta, Salicylic Acid, Acacia Decurrens Accia Decurrens Wax Flower Cera, Polyglycerin-3, Tocopherol, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/skinceuticals/glycolic-10-renew-overnight/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/skinceuticals/glycolic-10-renew-overnight/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/skinceuticals/glycolic-10-renew-overnight/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/skinceuticals/glycolic-10-renew-overnight/for/mature-skin
- France: https://lovi.care/skincare/fr/p/skinceuticals/glycolic-10-renew-overnight/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/skinceuticals/glycolic-10-renew-overnight/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/skinceuticals/glycolic-10-renew-overnight/for/mature-skin (this page)
- Spain: https://lovi.care/skincare/es/p/skinceuticals/glycolic-10-renew-overnight/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/skinceuticals/glycolic-10-renew-overnight/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/skinceuticals/glycolic-10-renew-overnight/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/skinceuticals/glycolic-10-renew-overnight/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/skinceuticals/glycolic-10-renew-overnight/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/skinceuticals/glycolic-10-renew-overnight/for/mature-skin