# SKIN1004 Madagascar Centella Tone Brightening Capsule Ampoule for acne-prone skin

**Lovi Fit: High fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/nl/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Brand: [SKIN1004](https://lovi.care/skincare/nl/brands/skin1004)
Category: [Serums and treatments](https://lovi.care/skincare/nl/best/serums)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for acne-prone skin; a few serums fit it even better.

## Why this fit

- Excellent for your combination, acne-prone skin as Centella Asiatica Extract and Niacinamide soothe inflammation and regulate sebum production, while 3-O-Ethyl Ascorbic Acid brightens and evens skin tone.
- Tranexamic Acid further aids in improving skin radiance and addressing blemishes, complementing the primary ingredients' actions.
- The formulation is safe for your skin, containing soothing ingredients like Centella Asiatica Extract and Panthenol with no harsh or irritating components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/nl/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/nl/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/nl/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/nl/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/nl/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/acne-prone-skin): High (this page)
- [Skin with dark spots](https://lovi.care/skincare/nl/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/nl/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/nl/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/nl/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/oily-acne-prone-skin): High

## Key ingredients

Centella Asiatica Extract, Niacinamide, Tranexamic Acid, 3-O-Ethyl Ascorbic Acid, Madecassoside

## What the research says

- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))

## What reviewers say

Based on a very large amount of data, users with sensitive and acne-prone skin highly praise this ampoule for its lightweight, fast-absorbing hydration that effectively calms redness without causing irritation. Many users report achieving a healthy glow and improved skin texture. However, the brightening of dark spots is often described as a slow, gradual process that requires consistent long-term use.

- Liked: Lightweight, fast absorbing (mostly mentioned)
- Liked: Generous size, value (often mentioned)
- Liked: Soothing and gentle (often mentioned)
- Disliked: Slow brightening results (often mentioned)
- Liked: Gradual brightening (sometimes noted)
- Disliked: Capsule texture (rarely noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Not moisturizing enough (rarely noted)

## How to apply

- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes SKIN1004 Tone Brightening Capsule Ampoule a great fit for acne-prone skin?

This product is a great fit for your acne-prone skin because Centella Asiatica Extract and Niacinamide soothe inflammation and balance oil production, while vitamin C and Tranexamic Acid brighten dark spots and even out your skin tone. It also contains gentle, soothing ingredients like Panthenol that help calm irritation without harsh components.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### Which ingredients make this serum a good fit for acne-prone skin?

Centella Asiatica Extract and Niacinamide make this serum a great fit for acne-prone skin because they soothe inflammation and regulate sebum production. Madecassoside and Panthenol also help repair the skin barrier and calm irritation without clogging pores.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### What does Centella Asiatica Extract do for acne-prone skin?

Centella asiatica extract helps calm angry skin, reduces redness, and supports healing for breakouts. It is unlikely to cause irritation and may improve overall skin clarity when used consistently.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/)

### What does Niacinamide do for acne-prone skin?

Niacinamide helps acne-prone skin by reducing both inflamed and uninflamed breakouts and calming redness. It is also very helpful for keeping oily skin balanced by cutting down on excess oil production, and it is well tolerated by most people.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38299457/), [Cureus, 2024](https://pubmed.ncbi.nlm.nih.gov/38725769/)

### Where does this serum go in a skincare routine for acne-prone skin?

This treatment goes in the evening routine after cleansing toner and before moisturizer. Putting it in the PM routine keeps things simple and helps avoid any extra sensitivity around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this treatment with retinol by applying the treatment first and following with your retinol, or by using them on alternating nights to keep your skin calm. This helps you balance blemish-fighting benefits while keeping your skin comfortable and reducing the likelihood of irritation.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### How often should I use this serum?

This treatment is a great fit for your acne-prone skin and is designed to be used in your evening routine. Centella Asiatica Extract and Niacinamide help soothe inflammation and balance oil, while brightening ingredients even out your skin tone safely.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### Can this serum clog pores, cause breakouts or purging for acne-prone skin?

This serum is unlikely to clog pores or cause breakouts for acne-prone skin. It features soothing ingredients like Centella Asiatica Extract and Niacinamide that help calm inflammation and control oil without harsh components.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/nl/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/acne-prone-skin) — Superior fit — €10.20 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/nl/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/acne-prone-skin) — Superior fit — €35.80 at Amazon
- [Clinique Fresh Pressed Daily Booster with Pure Vitamin C 10%](https://lovi.care/skincare/nl/p/clinique/fresh-pressed-daily-booster-with-pure-vitamin-c-10/for/acne-prone-skin) — Superior fit — €99.41 at Amazon

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/nl/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — €13.99 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/nl/p/some-by-mi/snail-truecica-miracle-repair-toner/for/acne-prone-skin) — Superior fit — €19.90 at Amazon
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/nl/p/skin1004/centella-cream/for/acne-prone-skin) — Superior fit — €19.20 at Amazon

## Where to buy

- Amazon.nl: €19.54 (https://www.amazon.nl/dp/B0H5K6TT6V?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- Notino: €12.90 (https://www.notino.nl/skin1004/madagascar-centella-tone-brightening-capsule-ampoule-hydraterende-serum-voor-stralende-en-gladde-huid/p-16153588/)
Prices checked 14 Oct – 6 Nov 2026.

## Ingredients

Centella Asiatica Extract, Butylene Glycol, Glycerin, Niacinamide, Tranexamic Acid, 1,2-Hexanediol, Water, Betaine, Madecassoside, Hydrogenated Lecithin, Xylitylglucoside, Anhydroxylitol, Xylitol, Panthenol, Zea Mays Starch, Arginine, Mannitol, 3-O-Ethyl Ascorbic Acid, Microcrystalline Cellulose, Lactobacillus Ferment, Hydroxyethylcellulose, Pentylene Glycol, Glucose, Ethylhexylglycerin, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Xanthan Gum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/acne-prone-skin (this page)
- Spain: https://lovi.care/skincare/es/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/acne-prone-skin