# Skin Better Science Alto Advanced Defense and Repair Serum for oily skin

**Lovi Fit: Average fit for oily skin.**
Oily Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/nl/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/oily-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Brand: [Skin Better Science](https://lovi.care/skincare/nl/brands/skin-better-science)
Category: [Serums and treatments](https://lovi.care/skincare/nl/best/serums)

This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily skin; other serums fit it better.

## Why this fit

- Offers moderate suitability for your oily skin, as niacinamide helps with seboregulation and antioxidant ingredients like Euterpe Oleracea Fruit Extract provide support, though stronger sebum-controlling agents are absent for optimal shine control.
- The serum provides excellent protection against environmental stressors with ergothioneine and arabidopsis thaliana extract, while glycerin and ubiquinone offer general hydration and antioxidant benefits.
- The product is safe for your oily skin, with no risks of irritation due to the absence of harsh ingredients and the inclusion of soothing components like Bisabolol and Camellia Sinensis Leaf Extract.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/nl/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/oily-skin): Average (this page)
- [Dry skin](https://lovi.care/skincare/nl/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/nl/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/nl/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/nl/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/nl/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/nl/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/nl/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/nl/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Niacinamide, Superoxide Dismutase, Tetrahexyldecyl Ascorbate, Carnosine, Ceramide Ap

## What the research says

- A triple combination of ergothioneine, collagen peptides, and sodium hyaluronate attenuated UV-induced skin damage ex vivo and improved facial skin hydration, elasticity, barrier function, and wrinkles in Chinese women. ([Frontiers in Nutrition, 2026](https://pubmed.ncbi.nlm.nih.gov/42698538/))
- Topical treatment with coenzyme Q10 formulas replenishes Q10 levels in the skin surface and deeper epidermis, augments cellular energy metabolism, and reduces free radicals while increasing antioxidant capacity in stressed skin. ([BioFactors, 2015](https://pubmed.ncbi.nlm.nih.gov/26648450/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of TAT-SOD significantly suppresses UVB-induced erythema formation, blood flow rise, and apoptotic sunburn cell formation in human volunteers compared to a vehicle control. ([European Journal of Pharmaceutics and Biopharmaceutics, 2016](https://pubmed.ncbi.nlm.nih.gov/27460952/))
- Topical treatment with the synthetic SOD/catalase mimetic EUK-134 reduced lipid peroxide levels both at baseline on non-irradiated human skin and at the surface of UVA-exposed skin when applied before or after irradiation, compared to controls. ([International Journal of Cosmetic Science, 2004](https://pubmed.ncbi.nlm.nih.gov/18492138/))
- Topical superoxide dismutase formulations maintained physical stability and enzymatic activity for 6 months at 4 and 30 degrees C, and effectively inhibited UVB-induced skin erythema for 48 hours, whereas formulations combined with alpha-tocopherol were unstable. ([European Journal of Pharmaceutics and Biopharmaceutics, 2007](https://pubmed.ncbi.nlm.nih.gov/17196809/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- A night cream containing melatonin, carnosine, and Helichrysum italicum extract reduced oxidative stress ex vivo and improved hydration, reduced transepidermal water loss, decreased wrinkles and spots, and lowered skin reactivity in 117 individuals over up to 12 weeks of nightly use. ([Dermatology and Therapy, 2020](https://pubmed.ncbi.nlm.nih.gov/32915393/))
- Supramolecular carnosine improves skin reactivity, upregulates Nrf2 expression, activates antioxidant defenses, and reduces AGE levels while demonstrating whitening efficacy in cells and clinical tests compared to conventional carnosine. ([Advanced Healthcare Materials, 2024](https://pubmed.ncbi.nlm.nih.gov/39279568/))
- A targeted skincare regimen containing active ingredients such as rhodophyceae extract, ergothioneine, and L-carnosine significantly reduced transepidermal water loss by 24.09%, improved skin elasticity, and decreased redness, dryness, and desquamation in thirty-five female Chinese participants over 4 weeks following advanced optimal pulse technology treatment. ([International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/40497421/))

## Why other serums fit oily skin better

- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))
- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week and build up to daily use if your skin tolerates it well.
- Apply the serum after cleansing and toning, but right before your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin. Let it absorb ⏱ for a minute before applying the next product.
- Apply the serum on clean and dry skin since your skin is not sensitive and you want to target oily shine. This helps control excess oil throughout the night.
- Avoid the delicate eye area and do a patch test before using the serum for the very first time.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Skin Better Alto Advanced Defense work for oily skin?

This serum works moderately well for oily skin, helping manage oil and protecting against environmental stress with antioxidants while remaining safe and gentle. Oily skin types need a product that includes strong oil-controlling ingredients and mattifying agents for the best shine control.
Sources: [Frontiers in Nutrition, 2026](https://pubmed.ncbi.nlm.nih.gov/42698538/), [BioFactors, 2015](https://pubmed.ncbi.nlm.nih.gov/26648450/)

### Which ingredients make this serum a good fit for oily skin?

Niacinamide helps control excess oil, while antioxidants like ergothioneine and coenzyme Q10 protect your skin from daily stress. Oily skin works best with treatments that combine sebum-controlling ingredients like niacinamide and zinc PCA with lightweight hydrators and soothing extracts to manage shine and pores without causing breakouts.
Sources: [Frontiers in Nutrition, 2026](https://pubmed.ncbi.nlm.nih.gov/42698538/), [BioFactors, 2015](https://pubmed.ncbi.nlm.nih.gov/26648450/)

### What does Niacinamide do for oily skin?

Niacinamide helps balance oily skin by significantly reducing excess oil production and shine. It is well tolerated and may improve skin texture without clogging pores.
Sources: [Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### What does Superoxide Dismutase do for oily skin?

Superoxide dismutase helps oily skin by neutralizing free radicals and managing oxidative stress that can worsen skin irritation and breakouts. This ingredient helps calm the skin and maintain a balanced, healthy look when used regularly.
Sources: [Antioxidants, 2023](https://pubmed.ncbi.nlm.nih.gov/37759978/), [European Journal of Pharmaceutics and Biopharmaceutics, 2016](https://pubmed.ncbi.nlm.nih.gov/27460952/)

### Where does this serum go in a skincare routine for oily skin?

This treatment serum goes in the evening routine after cleansing and before moisturizing, keeping things simple and safe around sun exposure. Oily skin of this type also needs stronger sebum-controlling ingredients to properly manage shine.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first and following with your retinol product, or by using this serum in the morning and your retinol at night. The formula is unlikely to cause irritation on oily skin since it contains soothing ingredients like bisabolol and green tea extract. Oily skin also needs stronger sebum-controlling agents for optimal shine control.

### How often should I use this serum?

This treatment serum fits into your evening routine, where you can apply it once a day after cleansing and toning. Using antioxidants like this helps protect your skin from daily environmental damage while keeping your routine simple and safe around sun exposure.
Sources: [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/), [BioFactors, 2015](https://pubmed.ncbi.nlm.nih.gov/26648450/)

### Can this serum clog pores, cause breakouts or purging for oily skin?

This serum is unlikely to clog pores or cause breakouts on oily skin, as it has a very safe profile with soothing ingredients like bisabolol and green tea leaf extract that keep irritation at bay. However, because it lacks stronger oil-controlling agents, oily skin often needs targeted sebum-regulating ingredients to better manage shine and prevent clogged pores.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for oily skin

- [Clinique Fresh Pressed Daily Booster with Pure Vitamin C 10%](https://lovi.care/skincare/nl/p/clinique/fresh-pressed-daily-booster-with-pure-vitamin-c-10/for/oily-skin) — Superior fit — €99.41 at Amazon
- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/nl/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/oily-skin) — Superior fit — €10.20 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/nl/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/oily-skin) — Superior fit — €35.80 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/nl/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — €21.00 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/nl/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — €19.90 at Amazon
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/nl/p/skin1004/centella-cream/for/oily-skin) — Superior fit — €19.20 at Amazon

## Where to buy

No store in Netherlands has a checked price for this product, so the page shows none.

## Ingredients

Acacia Decurrens Wax Flower, Acacia Senegal Gum, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Water, Arabidopsis Thaliana Extract, Arginine, Benzylidene Dimethoxydimethylindanone, Bisabolol, Buddleja Officinalis Flower Extract, Butylene Glycol, Camellia Sinensis Leaf Extract, Carbomer, Carnosine, Ceramide Ap, Ceramide Eop, Ceramide Np, Cetearyl Alcohol, Ceteth-20 Phosphate, Chlorogenic Acids, Cholesterol, Citric Acid, Coffea Arabica Extract Cell Leaf Coffee Extract Cell Leaf, Crocus Sativus Extract Cell Leaf Culture, Curcuma Longa Root Extract, Dextran, Dicetyl Phosphate, Diisostearyl Malate, Dimethyl Isosorbide, Ergothioneine, Ethylhexyl Olivate, Ethylhexylglycerin, Euterpe Oleracea Fruit Extract, Glycerin, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Helianthus Annuus Wax Seed Sunflower Wax Seed, Hydrolyzed Sodium Hyaluronate, Jojoba Esters, Lauryl Lactate, Lecithin, Linoleic Acid, Linolenic Acid, Methyl Gluceth-20, Micrococcus Lysate, Niacinamide, Olea Europaea Fruit Extract Olive Fruit Extract, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Pentylene Glycol, Phenoxyethanol, Phytosphingosine, Plankton Extract, Polyglycerin-3, Propanediol, Propanediol Dicaprylate Caprate, Pyrroloquinoline Quinone Allyl Ester, Ricinoleth-40, Sea Whip Extract, Sodium Hydroxide, Sodium Lauroyl Lactylate, Sodium Pca, Sodium Phytate, Steareth-2, Superoxide Dismutase, Tetrahexyldecyl Ascorbate, Theobroma Cacao Seed Extract, Tocopherol, Tocopheryl Acetate, Trifluoroacetyl Tripeptide-2, Ubiquinone, Vitis Vinifera Seed Extract Grape Seed Extract, Xanthan Gum, Zingiber Officinale Root Extract
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/oily-skin
- United Kingdom: https://lovi.care/skincare/uk/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/oily-skin
- Ireland: https://lovi.care/skincare/ie/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/oily-skin
- Germany: https://lovi.care/skincare/de/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/oily-skin
- France: https://lovi.care/skincare/fr/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/oily-skin
- Italy: https://lovi.care/skincare/it/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/oily-skin
- Netherlands: https://lovi.care/skincare/nl/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/oily-skin (this page)
- Spain: https://lovi.care/skincare/es/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/oily-skin
- Canada: https://lovi.care/skincare/ca/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/oily-skin
- Australia: https://lovi.care/skincare/au/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/oily-skin
- Singapore: https://lovi.care/skincare/sg/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/oily-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/oily-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/oily-skin