# SENTÉ Bio Complete Serum for dry sensitive skin

**Lovi Fit: Average fit for dry sensitive skin.**
Dry Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/nl/p/sente/bio-complete-serum/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Brand: [SENTÉ](https://lovi.care/skincare/nl/brands/sente)
Category: [Serums and treatments](https://lovi.care/skincare/nl/best/serums)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry sensitive skin; other serums fit it better.

## Why this fit

- Offers moderate suitability for your dry and sensitive skin, as Glycerin and Sodium Hyaluronate provide some hydration, while Retinol and Myristoyl Pentapeptide-17 effectively target fine lines and wrinkles.
- The inclusion of Allantoin and Panthenol further supports skin comfort and barrier function, though additional emollient ingredients would enhance overall hydration for your dry skin.
- The product is safe for your skin, with no identified risks of irritation due to its gentle formulation and absence of harsh components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/nl/p/sente/bio-complete-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/nl/p/sente/bio-complete-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/nl/p/sente/bio-complete-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/nl/p/sente/bio-complete-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/nl/p/sente/bio-complete-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/nl/p/sente/bio-complete-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/nl/p/sente/bio-complete-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/nl/p/sente/bio-complete-serum/for/dry-sensitive-skin): Average (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/nl/p/sente/bio-complete-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Sodium Hyaluronate, Retinol, Glycosaminoglycans, Heparan Sulfate, Niacinamide

## What the research says

- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))
- Topical stabilized retinol treatment induced HAS gene expression and increased hyaluronic acid production in human skin in vitro, ex vivo, and in vivo compared to vehicle. ([Archives of Dermatological Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28247017/))
- Topical treatment with sphingolipids and glycosaminoglycans attenuated clinical worsening and reduced CADESI and PVAS scores compared to the untreated control group in house dust mite-allergic beagle dogs. ([BMC Veterinary Research, 2020](https://pubmed.ncbi.nlm.nih.gov/32197613/))
- Glycosaminoglycans restored type I collagen synthesis, reduced matrix metalloproteinase-1 levels, upregulated tissue inhibitor of metalloproteinase-1, and attenuated apoptosis in tumor necrosis factor-alpha-stimulated human dermal fibroblasts by inhibiting extracellular signal-regulated kinase/activator protein-1 signaling. ([International Journal of Molecular Medicine, 2018](https://pubmed.ncbi.nlm.nih.gov/29436595/))
- Fraction 3 of glycosaminoglycans from Liparis tessellatus eggs showed 20.1% tyrosinase inhibition at 50mg/mL and effective skin regeneration activities at 200mg/mL against skin fibroblast CCD-986sk cell lines. ([International Journal of Biological Macromolecules, 2017](https://pubmed.ncbi.nlm.nih.gov/28917941/))
- A topical eye cream containing low molecular weight heparan sulfate and naturally derived extracts improved periorbital hyperpigmentation, fine and coarse wrinkles, puffiness, and dark circles in 15 subjects over 12 weeks. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30636356/))
- Topical low molecular weight heparan sulfate improved periorbital discoloration and wrinkles starting at week two with continuous improvement up to week 12. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32562303/))
- Topical low molecular weight heparan sulfate improved skin hydration, firmness, elasticity, barrier function, and fine lines and wrinkles in 15 patients over 8 weeks. ([Journal of Drugs in Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/26151781/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))

## Why other serums fit dry sensitive skin better

- Tocopherol succinate-loaded ethosomal gel increased skin deposition, stability, moisture, and mechanical properties in 13 human subjects compared to a control gel over 12 weeks. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35274433/))
- In 50 participants with sensitive skin, a Ceramide NP C15-containing emollient improved skin barrier function with a significant reduction in transepidermal water loss and induced modest changes in skin microbiota compared to the vehicle. ([Skin Pharmacology and Physiology, 2026](https://pubmed.ncbi.nlm.nih.gov/41758783/))
- Hydrogels containing vitamin E-loaded nanostructured lipid carriers exhibited better occlusive properties and long-lasting effects, while vitamin E-loaded nanoemulsions performed a faster skin hydration effect and were selected as more attractive for skin application. ([Colloids and Surfaces. B, Biointerfaces, 2019](https://pubmed.ncbi.nlm.nih.gov/30974262/))

## What reviewers say

Based on limited data, this serum is highly praised for its anti-aging effects, improving skin texture and firmness while reducing fine lines. Some users experienced a greasy feel or slow results, and a negligible number mentioned the presence of fragrance.

- Liked: Gentle formula (mostly mentioned)
- Liked: Improves texture (often mentioned)
- Liked: Anti-aging benefits (sometimes noted)
- Liked: Hydrating (sometimes noted)
- Disliked: Contains fragrance (rarely noted)
- Disliked: Greasy feel (rarely noted)
- Disliked: Slow results (rarely noted)

## How to apply

- Use this PM routine for your evening skincare. Start using the serum 3 times a week and increase to daily use if your skin feels comfortable.
- Apply the serum after cleansing and toner, but right before your moisturizer. This step locks in deep hydration for dry skin.
- Gently press 2-3 drops of the serum into your skin using your palms. Let it absorb completely for a minute ⏱ before applying your next product.
- Since your skin is sensitive, apply the serum on completely dry skin for better tolerance and less irritation.
- Avoid the sensitive eye area during application. Always do a patch test before your first use to ensure your skin reacts well.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does SENTÉ Bio Complete Serum work for dry sensitive skin?

This serum works moderately well for dry sensitive skin because hydrating ingredients like glycerin and sodium hyaluronate provide some moisture while retinol targets fine lines. It is unlikely to cause irritation due to its gentle formula and soothing ingredients like allantoin and panthenol, though a product of this type needs richer softening ingredients to fully comfort dry skin.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for dry sensitive skin?

Glycerin and sodium hyaluronate provide hydration, while retinol and myristoyl pentapeptide-17 target fine lines, and allantoin and panthenol support skin comfort. However, this skin type needs extra rich moisturizing ingredients to build better hydration.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Hyaluronic Acid do for dry sensitive skin?

Hyaluronic acid is a great fit for dry, sensitive skin because it brings a large boost in hydration, making the skin feel soft and smooth while improving barrier function. It helps calm tightness and dryness, and is unlikely to cause irritation.
Sources: [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/), [Dermatology and Therapy, 2021](https://pubmed.ncbi.nlm.nih.gov/34176098/)

### What does Retinol do for dry sensitive skin?

Retinol is often too strong for dry sensitive skin because it may cause scaling and stinging, so a product of this type needs gentle soothing ingredients and extra moisture to keep the skin calm and smooth.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/), [Toxicology Letters, 2003](https://pubmed.ncbi.nlm.nih.gov/14615068/)

### Where does this serum go in a skincare routine for dry sensitive skin?

This serum goes in the evening routine after your toner and before your moisturizer. A product of this type needs extra soothing and softening ingredients to provide better hydration for dry skin.

### Can I use this serum with glycolic acid, and in what order?

Using this serum with glycolic acid may easily irritate dry and sensitive skin, so it is best to use them on alternate nights or skip the glycolic acid when applying this treatment. To keep this skin type comfortable, a product of this type needs rich moisturizing ingredients and oils to lock in hydration and prevent dryness.

### How often should I use this serum?

You can use this treatment in your evening routine, applying it once a day or a few times a week as your skin adjusts. Retinols serve as a low-risk mainstay for skin rejuvenation, though a product of this type needs extra rich moisturizing ingredients to fully comfort dry skin.
Sources: [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/)

### Can this serum clog pores, cause breakouts or purging for dry sensitive skin?

This serum is unlikely to clog pores or cause breakouts for dry sensitive skin, as its formulation is gentle and free of heavy, pore-clogging oils. However, because it contains retinol, you may experience mild initial purging or flaking as your skin adjusts to cellular renewal.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry sensitive skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/nl/p/skinceuticals/c-e-ferulic/for/dry-sensitive-skin) — Superior fit — €160.00 at Amazon
- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/nl/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/dry-sensitive-skin) — Superior fit — €10.20 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/nl/p/augustinus-bader/the-serum/for/dry-sensitive-skin) — Superior fit — €474.90 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/nl/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — €15.00 at Amazon
- Soothing Toner: [SKIN1004 Centella Asiatica Toning Toner](https://lovi.care/skincare/nl/p/skin1004/centella-asiatica-toning-toner/for/dry-sensitive-skin) — Superior fit — €17.96 at Amazon
- Moisturizer with Sun Protection: [d'Alba UVessence Mild Waterfull Sun Cream SPF 50](https://lovi.care/skincare/nl/p/d-alba/uvessence-mild-waterfull-sun-cream-spf-50/for/dry-sensitive-skin) — Superior fit — €16.75 at Amazon

## Where to buy

No store in Netherlands has a checked price for this product, so the page shows none.

## Ingredients

Water, Butylene Glycol, Dipropylene Glycol, Cyclopentasiloxane, Peg-12 Dimethicone Crosspolymer, Dimethicone Crosspolymer, Dimethicone Vinyl Dimethicone Crosspolymer, Dimethiconol, Dimethicone, Laureth-23, Laureth-4, Glycerin, Heparan Sulfate, Pentylene Glycol, Retinyl Safflowerate, Retinol, Lysophosphatidic Acid, Myristoyl Nonapeptide-3, Myristoyl Pentapeptide-17, Ethyl Safflowerate, Ethyl Flaxseedate, Dipalmitoyl Hydroxyproline, Allantoin, Panthenol, Sodium Hyaluronate, Sodium Ascorbyl Phosphate, Alanine, Arginine Hcl, Asparagine, Aspartic Acid, Cystine, Glutamic Acid, Glutamine, Histidine Hcl, Isoleucine, Leucine, Lysine Hcl, Acetyl Methionine, Phenylalanine, Proline, Serine, Threonine, Tryptophan, Tyrosine, Valine, Calcium Pantothenate, Folic Acid, Inositol, Niacinamide, Pyridoxal Hcl, Riboflavin, Thiamine Hcl, Calcium Chloride, Magnesium Sulfate, Potassium Chloride, Sodium Chloride, Sodium Phosphate, Beta-Carotene, Polysorbate 80, Polyaminopropyl Biguanide, Tromethamine
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/sente/bio-complete-serum/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/sente/bio-complete-serum/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/sente/bio-complete-serum/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/sente/bio-complete-serum/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/sente/bio-complete-serum/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/sente/bio-complete-serum/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/sente/bio-complete-serum/for/dry-sensitive-skin (this page)
- Spain: https://lovi.care/skincare/es/p/sente/bio-complete-serum/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/sente/bio-complete-serum/for/dry-sensitive-skin
- Australia: https://lovi.care/skincare/au/p/sente/bio-complete-serum/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/sente/bio-complete-serum/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/sente/bio-complete-serum/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/sente/bio-complete-serum/for/dry-sensitive-skin