Peach Slices Redness Relief Azelaic Acid Serum for mature skin

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Questions and answers

What the research says

• A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability.

  The Journal of Dermatological Treatment, 2017

• Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment.

  American Journal of Clinical Dermatology, 2002

• A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment.

  Journal of Cosmetic Dermatology, 2025

• Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements.

  Indian Journal of Pharmaceutical Sciences, 2016

• Topical C-phycocyanin application on UVB-irradiated mouse skin improved macroscopic characteristics, reduced epidermal thickening, increased hydroxyproline and antioxidant enzyme activities, and decreased inflammatory factors, oxidative stress, and matrix metalloproteinases.

  Frontiers in Bioengineering and Biotechnology, 2023

• Azelaic acid nanocrystal hydrogel 10% achieved a higher success rate and greater lesion reduction than azelaic acid cream 20% in patients with mild to moderate facial acne.

  Pharmaceutics, 2021

• Application of 15% azelaic acid gel significantly reduced post-inflammatory erythema and hyperpigmentation, decreased hemoglobin and melanin content, improved quality of life, and contributed to acne improvement in patients with mild to moderate acne compared to placebo.

  Dermatology and Therapy, 2024

• Topical application of a dermocosmetic containing Myrtus communis extract and azelaic acid reduced acne relapses and helped maintain remission compared to a light moisturizing cream in adult females in the acne maintenance phase over 16 weeks.

  Journal of the European Academy of Dermatology and Venereology, 2023

• Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing.

  Journal of Alternative and Complementary Medicine, 2020

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.

  Journal of Cosmetic Dermatology, 2019

• Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans.

  Arzneimittel-Forschung, 2000

• Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two.

  Auris, Nasus, Larynx, 2020

• A combination serum containing galactomyces ferment filtrate, dexpanthenol, and Centella asiatica effectively treated post-acne hyperpigmentation in subjects with colored skin by significantly increasing lightness scores in Fitzpatrick skin type V and reducing the melanin index in Fitzpatrick skin type IV compared to placebo.

  Skinmed, 2021

• Supplementation of a broad-spectrum sunscreen with Spirulina and dimethylmethoxy chromanol significantly improved skin pigmentation, reduced collagen degradation, and enhanced net elasticity in 44 healthy subjects after 84 days compared to sunscreen alone.

  European Journal of Pharmaceutical Sciences, 2017

• Spirulina and its bioactive compounds provide antioxidant, anti-aging, and photoprotective benefits in cosmetic formulations by promoting skin hydration, reducing wrinkles, enhancing collagen production, and protecting skin cells from UV-induced apoptosis.

  Biotech), 2025

• Topical application of a gel formulated with spray dried Spirulina protein and muscadine grape pomace polyphenol particles mitigated oxidative protein damage, inflammation, and skin barrier disruption in ex vivo human biopsies exposed to diesel engine exhaust.

  Antioxidants, 2023

• Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel.

  Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016

• A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo.

  Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020

• An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment.

  Aesthetic Plastic Surgery, 2018

Ingredients

Water, Azelaic Acid, Butylene Glycol, Dipropylene Glycol, 1,2-Hexanediol, Propanediol, Caprylic Capric Triglyceride, Panthenol, Cetyl Ethylhexanoate, Butylene Glycol Dicaprylate Dicaprate, Spirulina Platensis Extract, Rhodomyrtus Tomentosa Fruit Extract, Artemisia Vulgaris Extract, Centella Asiatica Extract, Spinach Leaf Extract, Brassica Oleracea Italica Extract, Tapioca Starch, Allantoin, Betaine, Sodium Polyacryloyldimethyl Taurate, Arginine, Ethylhexyl Palmitate, Sorbitan Isostearate, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Dextrin, Carthamus Tinctorius Flower Extract, Gardenia Florida Fruit Extract, Polyacrylate-13, Hydrogenated Polyisobutene, Polyglyceryl-10 Laurate, Caprylyl Glycol

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.