# PanOxyl PM Balancing Repair Moisturizer for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/nl/p/panoxyl/pm-balancing-repair-moisturizer/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Brand: [PanOxyl](https://lovi.care/skincare/nl/brands/panoxyl)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/nl/best/moisturizers)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for mature skin; a few moisturizers fit it even better.

## Why this fit

- Highly suitable for your normal skin as niacinamide and sodium hyaluronate provide excellent humectant action and barrier repair, addressing your concerns with wrinkles and fine lines by supporting skin repair and antioxidant protection.
- Glycerin and Vitamin E further enhance moisturizing and plumping effects, contributing to smoother, more hydrated skin.
- The formulation is safe for your normal skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/nl/p/panoxyl/pm-balancing-repair-moisturizer/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/nl/p/panoxyl/pm-balancing-repair-moisturizer/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/nl/p/panoxyl/pm-balancing-repair-moisturizer/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/nl/p/panoxyl/pm-balancing-repair-moisturizer/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/nl/p/panoxyl/pm-balancing-repair-moisturizer/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/nl/p/panoxyl/pm-balancing-repair-moisturizer/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/nl/p/panoxyl/pm-balancing-repair-moisturizer/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/nl/p/panoxyl/pm-balancing-repair-moisturizer/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/nl/p/panoxyl/pm-balancing-repair-moisturizer/for/oily-acne-prone-skin): High

## Key ingredients

Niacinamide, Ceramides, Sodium Hyaluronate, Centella Asiatica Leaf Extract, Glycerin

## What the research says

- Treatment with a combination of niacinamide and hyaluronic acid improved skin aging signs and demonstrated a senomorphic effect by decreasing SASP and autocrine signaling genes in women. ([Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical treatment of nicotinamide, alone or in combination with other active ingredients, reduces the progression of skin aging and hyperpigmentation in clinical trials while being well tolerated. ([Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical 2% niacinamide significantly decreased sebum excretion rate in Japanese individuals and casual sebum levels in Caucasian individuals compared to placebo or baseline. ([Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))

## What reviewers say

Based on a very large amount of data, users with acne-prone and oily skin generally praise this moisturizer for its lightweight, non-greasy hydration that effectively calms redness and minimizes breakouts without clogging pores. A significant subset of users reports adverse reactions, including a strong, unpleasant chemical scent and immediate burning or stinging sensations upon application.

- Liked: Lightweight texture (mostly mentioned)
- Liked: Calms acne (often mentioned)
- Liked: Effective hydration (often mentioned)
- Disliked: Unpleasant smell (often mentioned)
- Liked: Good value (sometimes noted)
- Disliked: Burning sensation (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Irritation/dryness (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help smooth fine lines.
- Apply this product after your toner and serum, but before your SPF in the morning. Follow your cleanser and toner steps to keep your skin balanced.
- Gently press a small amount into your face and neck. Avoid rubbing the skin too harshly to prevent extra tension.
- Apply the moisturizer on slightly damp skin to help lock in extra moisture. Clean skin helps the product absorb much more evenly.
- Avoid the sensitive eye area during application. Do a quick patch test before your very first use to stay safe.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes PanOxyl PM Balancing Repair Moisturizer a great fit for mature skin?

PanOxyl PM Balancing Repair Moisturizer is a great fit for mature skin because niacinamide and sodium hyaluronate provide excellent moisture-holding action and barrier repair, which helps smooth out wrinkles and fine lines. Glycerin and Vitamin E further boost hydration and plumping, leading to softer, smoother skin with a very low risk of irritation.
Sources: [Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this moisturizer a good fit for mature skin?

Niacinamide, ceramides, and sodium hyaluronate make this moisturizer a great fit for mature skin by supporting skin repair, smoothing fine lines, and providing deep hydration. Glycerin and Vitamin E further help plump the skin, leaving it feeling smooth and well-moisturized with a very low risk of irritation.
Sources: [Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Niacinamide do for mature skin?

Niacinamide helps mature skin by smoothing out fine lines and wrinkles, reducing dark spots, and improving overall skin elasticity. It is also very well tolerated and supports a strong skin barrier to keep skin looking healthy.
Sources: [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### What do Ceramides do for mature skin?

Ceramides help keep mature skin hydrated and smooth by repairing the outer moisture barrier and supporting water retention. This type of ingredient helps improve skin texture and elasticity while reducing dryness, which makes it particularly useful for aging skin that tends to lose moisture easily.
Sources: [Dermatologic Therapy, 2019](https://pubmed.ncbi.nlm.nih.gov/31585489/), [International Journal of Immunopathology and Pharmacology, 2008](https://pubmed.ncbi.nlm.nih.gov/18336739/)

### Where does this moisturizer go in a skincare routine for mature skin?

This moisturizer goes as the final step in the evening routine and right before sunscreen in the morning routine. Using it regularly helps keep your mature skin soft, smooth, and well-hydrated.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this moisturizer with retinol, and in what order?

You can use this moisturizer with retinol because its barrier-repairing and soothing ingredients help offset dryness and irritation. Apply the retinol first, let it absorb, and then follow with the moisturizer to keep your skin calm and hydrated.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this moisturizer?

This moisturizer is suitable for daily use to help keep mature skin soft and smooth. Applying it regularly supports skin moisture and barrier function, helping to reduce the look of fine lines and wrinkles over time.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this moisturizer clog pores, cause breakouts or purging for mature skin?

PanOxyl PM Balancing Repair Moisturizer is unlikely to cause breakouts for mature skin, as only a small number of reviewers report this issue. The formula is designed with gentle ingredients like glycerin and ceramides that hydrate without clogging pores.

### Can I use this moisturizer around the eyes or on my body?

Yes, you can use this moisturizer on your body and around the eyes to help smooth fine lines and boost hydration. Its gentle blend of niacinamide, ceramides, and sodium hyaluronate is well-tolerated by thin skin areas.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37896378/)

### Is this moisturizer fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for mature skin

- [L'Occitane Immortelle Divine Cream](https://lovi.care/skincare/nl/p/l-occitane/immortelle-divine-cream/for/mature-skin) — Superior fit — €69.99 at Amazon
- [The Ordinary Natural Moisturizing Factors + HA](https://lovi.care/skincare/nl/p/the-ordinary/natural-moisturizing-factors-ha/for/mature-skin) — High fit — €13.02 at Amazon
- [MISSHA Super Aqua Ultra Hyalron Cream](https://lovi.care/skincare/nl/p/missha/super-aqua-ultra-hyalron-cream/for/mature-skin) — High fit — €39.42 at Amazon

## Pairs well with

- Cleanser: [d'Alba White Truffle Return Oil Cream Cleanser](https://lovi.care/skincare/nl/p/d-alba/white-truffle-return-oil-cream-cleanser/for/mature-skin) — Superior fit — €25.07 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/nl/p/some-by-mi/snail-truecica-miracle-repair-toner/for/mature-skin) — Superior fit — €19.90 at Amazon
- SPF: [SKIN1004 MADAGASCAR CENTELLA AIR-FIT SUNCREAM PLUS](https://lovi.care/skincare/nl/p/skin1004/madagascar-centella-air-fit-suncream-plus/for/mature-skin) — Superior fit — €14.70 at Amazon

## Where to buy

- Amazon.nl: €26.99 (https://www.amazon.nl/dp/B0C1HKM67J?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Glycerin, Niacinamide, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Linoleic Acid, Sphingolipids Ceramides, Tocopherol Vitamin E, Sodium Hyaluronate, Centella Asiatica Leaf Extract, Allantoin, Phenylpropanol, Hydroxyacetophenone, Propanediol, Caprylyl Glycol, Oleic Acid, Palmitic Acid, Polysorbate 60, Sorbitan Isostearate, Stearic Acid, Tetrasodium Glutamate Diacetate, 1,2-Hexanediol, Linolenic Acid, Polylysine
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/panoxyl/pm-balancing-repair-moisturizer/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/panoxyl/pm-balancing-repair-moisturizer/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/panoxyl/pm-balancing-repair-moisturizer/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/panoxyl/pm-balancing-repair-moisturizer/for/mature-skin
- France: https://lovi.care/skincare/fr/p/panoxyl/pm-balancing-repair-moisturizer/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/panoxyl/pm-balancing-repair-moisturizer/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/panoxyl/pm-balancing-repair-moisturizer/for/mature-skin (this page)
- Spain: https://lovi.care/skincare/es/p/panoxyl/pm-balancing-repair-moisturizer/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/panoxyl/pm-balancing-repair-moisturizer/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/panoxyl/pm-balancing-repair-moisturizer/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/panoxyl/pm-balancing-repair-moisturizer/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/panoxyl/pm-balancing-repair-moisturizer/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/panoxyl/pm-balancing-repair-moisturizer/for/mature-skin