# Olay Regenerist Regenerating Serum for combination skin

**Lovi Fit: High fit for combination skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/nl/p/olay/regenerist-regenerating-serum/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Brand: [Olay](https://lovi.care/skincare/nl/brands/olay)
Category: [Serums and treatments](https://lovi.care/skincare/nl/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for combination skin; a few serums fit it even better.

## Why this fit

- Highly suitable for your combination skin as niacinamide helps regulate oil production in your oily areas while glycerin provides essential hydration for your drier zones.
- The serum offers excellent skin regeneration, smoothing texture and minimizing fine lines with ingredients like palmitoyl pentapeptide-4.
- The safety profile is excellent, with no risks of irritation for your combination skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/nl/p/olay/regenerist-regenerating-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/nl/p/olay/regenerist-regenerating-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/nl/p/olay/regenerist-regenerating-serum/for/combination-skin): High (this page)
- [Sensitive skin](https://lovi.care/skincare/nl/p/olay/regenerist-regenerating-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/nl/p/olay/regenerist-regenerating-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/nl/p/olay/regenerist-regenerating-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/nl/p/olay/regenerist-regenerating-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/nl/p/olay/regenerist-regenerating-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/nl/p/olay/regenerist-regenerating-serum/for/oily-acne-prone-skin): High

## Key ingredients

Niacinamide, Palmitoyl Pentapeptide-4, Glycerin, Tocopheryl Acetate, Allantoin

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical palmitoyl pentapeptide (pal-KTTKS) provided significant improvement versus placebo control in the reduction of wrinkles and fine lines in Caucasian female subjects. ([International Journal of Cosmetic Science, 2005](https://pubmed.ncbi.nlm.nih.gov/18492182/))
- Combined therapy using a topical hyaluronic acid-niacinamide-Matrixyl serum and a multimodal facial device decreased TruSkin age by five years and reduced wrinkles more effectively than the serum alone in a 41-year-old woman with moderate facial aging over 12 weeks. ([Cureus, 2026](https://pubmed.ncbi.nlm.nih.gov/42500768/))
- A functionalized dendrimer nanocarrier delivers active ingredients into the dermis and enhances collagen production in human dermal fibroblasts by co-delivering all-trans retinol and palmitoyl pentapeptide-4. ([Acta Biomaterialia, 2025](https://pubmed.ncbi.nlm.nih.gov/39694719/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40642809/))
- Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate. ([Contemporary Clinical Trials Communications, 2021](https://pubmed.ncbi.nlm.nih.gov/34471722/))
- Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590207/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))

## What reviewers say

Based on a very large amount of data, users love this serum's lightweight, silky texture that absorbs quickly, making it ideal for layering. Many report softer, hydrated skin and a reduction in fine lines, contributing to a smoother appearance. A small number of users experienced breakouts or found the texture sticky.

- Liked: Effective hydration (mostly mentioned)
- Liked: Silky texture (mostly mentioned)
- Liked: Convenient packaging (sometimes noted)
- Liked: Fragrance-free option (sometimes noted)
- Liked: Visible results (sometimes noted)
- Disliked: Ingredient concerns (rarely noted)
- Disliked: Packaging flaws (rarely noted)
- Disliked: Skin reactions (rarely noted)
- Disliked: Texture issues (rarely noted)
- Disliked: Value for money (rarely noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Olay Regenerist Regenerating Serum a great fit for combination skin?

Olay Regenerist Regenerating Serum is a great fit because niacinamide helps balance oil in your shiny zones while glycerin brings much-needed moisture to your dry spots. It also smooths texture and softens fine lines safely without any harsh ingredients that might upset your skin.
Sources: [International Journal of Cosmetic Science, 2005](https://pubmed.ncbi.nlm.nih.gov/18492182/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for combination skin?

Niacinamide helps regulate oil in your oily zones while glycerin provides needed hydration for your drier areas. Palmitoyl pentapeptide-4 further supports this by smoothing texture and minimizing fine lines.
Sources: [International Journal of Cosmetic Science, 2005](https://pubmed.ncbi.nlm.nih.gov/18492182/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Niacinamide do for combination skin?

Niacinamide helps balance oily areas by reducing excess shine and pore size while keeping dry patches hydrated and smooth. It also works to calm redness and even out skin tone, making it very suitable for combination skin.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### What does Palmitoyl Pentapeptide-4 do for combination skin?

Palmitoyl Pentapeptide-4 helps smooth fine lines and wrinkles on combination skin by boosting collagen production. It is unlikely to cause irritation and may improve skin texture with regular use.
Sources: [International Journal of Cosmetic Science, 2005](https://pubmed.ncbi.nlm.nih.gov/18492182/), [Cureus, 2026](https://pubmed.ncbi.nlm.nih.gov/42500768/)

### Where does this serum go in a skincare routine for combination skin?

This serum goes in your evening routine, applied after cleansing and toning and before your moisturizer. Putting it in the evening keeps things simple and provides extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to provide essential hydration and smoothing benefits, and following with your retinol once it absorbs. This approach is unlikely to cause irritation for your combination skin since the formula contains no harsh or prohibited ingredients.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### How often should I use this serum?

You can use this serum in your evening routine for simplicity and extra safety around sun exposure, or as part of a weekly care routine. It is a great fit for your combination skin because niacinamide helps balance oil in oily areas while glycerin hydrates drier zones, and it is very safe and unlikely to cause irritation.
Sources: [International Journal of Cosmetic Science, 2005](https://pubmed.ncbi.nlm.nih.gov/18492182/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can this serum clog pores, cause breakouts or purging for combination skin?

This serum is a great fit for your combination skin because niacinamide helps balance your oily areas while glycerin provides lightweight moisture for your dry zones, and it is unlikely to cause breakouts or irritation due to its very safe ingredient makeup.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Cureus, 2026](https://pubmed.ncbi.nlm.nih.gov/42500768/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/nl/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/combination-skin) — Superior fit — €10.20 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/nl/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin) — Superior fit — €35.80 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/nl/p/augustinus-bader/the-serum/for/combination-skin) — Superior fit — €474.90 at Amazon

## Pairs well with

- Cleanser: [Dr. Althea Amino Acid Gentle Bubble Cleanser](https://lovi.care/skincare/nl/p/dr-althea/amino-acid-gentle-bubble-cleanser/for/combination-skin) — Superior fit — €16.50 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/nl/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — €36.00 at Amazon
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/nl/p/skin1004/centella-cream/for/combination-skin) — Superior fit — €19.20 at Amazon

## Where to buy

No store in Netherlands has a checked price for this product, so the page shows none.

## Ingredients

Water, Dimethicone, Glycerin, Niacinamide, Dimethicone Crosspolymer, Polymethylsilsesquioxane, Panthenol, Polyethylene, Palmitoyl Pentapeptide-4, Sodium Peg-7 Olive Carboxylate Oil, Tocopheryl Acetate, Allantoin, Camellia Sinensis Leaf Extract, Dimethiconol, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Dmdm Hydantoin, Iodopropynyl Butylcarbamate, Acrylamide Sodium Acryloyldimethyltaurate Copolymer, C13-14 Isoparaffin, Aminomethyl Propanol, Laureth-4, Laureth-7, Disodium Edta
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/olay/regenerist-regenerating-serum/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/olay/regenerist-regenerating-serum/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/olay/regenerist-regenerating-serum/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/olay/regenerist-regenerating-serum/for/combination-skin
- France: https://lovi.care/skincare/fr/p/olay/regenerist-regenerating-serum/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/olay/regenerist-regenerating-serum/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/olay/regenerist-regenerating-serum/for/combination-skin (this page)
- Spain: https://lovi.care/skincare/es/p/olay/regenerist-regenerating-serum/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/olay/regenerist-regenerating-serum/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/olay/regenerist-regenerating-serum/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/olay/regenerist-regenerating-serum/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/olay/regenerist-regenerating-serum/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/olay/regenerist-regenerating-serum/for/combination-skin