# numbuzin Pantothenic B5 Active Soothing Cream for dry skin

**Lovi Fit: High fit for dry skin.**
Dry Skin Fit: Superior · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/nl/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Brand: [numbuzin](https://lovi.care/skincare/nl/brands/numbuzin)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/nl/best/moisturizers)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for dry skin; a few moisturizers fit it even better.

## Why this fit

- Excellent suitability for your dry skin is provided by Panthenol and Glycerin, which offer humectant action and support barrier repair, while Niacinamide further aids in smoothing texture.
- The formula also includes Centella Asiatica Extract to soothe and hydrate, making it beneficial for dry or flaky skin concerns.
- This product is safe for your skin as it contains no harsh ingredients and includes soothing components like Panthenol and Centella Asiatica Extract.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/nl/p/numbuzin/pantothenic-b5-active-soothing-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/nl/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dry-skin): High (this page)
- [Combination skin](https://lovi.care/skincare/nl/p/numbuzin/pantothenic-b5-active-soothing-cream/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/nl/p/numbuzin/pantothenic-b5-active-soothing-cream/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/nl/p/numbuzin/pantothenic-b5-active-soothing-cream/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/nl/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/nl/p/numbuzin/pantothenic-b5-active-soothing-cream/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/nl/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/nl/p/numbuzin/pantothenic-b5-active-soothing-cream/for/oily-acne-prone-skin): High

## Key ingredients

Pantothenic Acid Vitamin B5, Niacinamide, Centella Asiatica Extract, Aloe Barbadensis Flower Extract, Glycerin

## What the research says

- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Panthenyl triacetate (PTA) demonstrated skin de-acetylation into panthenol, stimulated energetic and synthesis metabolic pathways, and achieved a statistically significant improvement in wound healing after 72 hours compared to saline treatment in human volunteers, outperforming panthenol in long-lasting wound healing action. ([Journal of Cosmetic Science, 2012](https://pubmed.ncbi.nlm.nih.gov/22487447/))
- A comprehensive topical regimen incorporating niacinamide, Pro-Xylane, and panthenol following PicoWay laser treatment decreased transepidermal water loss, increased hydration and skin elasticity, reduced wrinkles and redness, and improved skin tone in 88 Chinese females compared to a standard care control group. ([Lasers in Medical Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42686896/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief. ([Plastic and Reconstructive Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29649056/))
- Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo. ([Journal of Alternative and Complementary Medicine, 2010](https://pubmed.ncbi.nlm.nih.gov/20569031/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))

## What reviewers say

Based on a very large amount of data, this lightweight gel-cream is widely celebrated by users with oily and acne-prone skin for its ability to hydrate without clogging pores or leaving a greasy residue. While it effectively soothes redness and controls excess sebum, users with dry or dehydrated skin often find it lacks sufficient moisture, particularly during colder months.

- Liked: Lightweight gel texture (mostly mentioned)
- Liked: Soothing & calming (often mentioned)
- Disliked: Insufficient moisture (often mentioned)
- Liked: Non-comedogenic (sometimes noted)
- Liked: Sebum/oil control (sometimes noted)
- Disliked: Breakouts/Reactions (rarely noted)
- Disliked: Packaging concerns (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine. Start using it 3 times a week and work your way up to daily use.
- Apply your moisturizer after your toner and before your sunscreen in the morning. At night, use it as the final step after your serum.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing to keep your dry skin happy.
- Apply the moisturizer on slightly damp skin to help lock in extra hydration. This is great for soothing dry and flaky areas .
- Avoid the sensitive eye area and do a patch test before your first use .
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Numbuzin Pantothenic B5 Active Soothing Cream a great fit for dry skin?

This moisturizer is a great fit for your dry skin because Glycerin and Panthenol draw in moisture to repair the skin barrier, while Niacinamide helps smooth texture. Additionally, Centella Asiatica Extract works to calm and hydrate flaky areas safely without harsh ingredients.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Which ingredients make this cream a good fit for dry skin?

Panthenol and Glycerin make this cream a great fit because they draw moisture into dry skin and help repair its barrier, while Niacinamide and Centella Asiatica Extract further soothe and smooth texture. These ingredients help keep skin soft and comfortable.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### What does Pantothenic Acid do for dry skin?

Pantothenic Acid helps keep dry skin soft by holding in moisture and calming irritation. It improves how well the skin barrier holds water and makes rough skin feel smooth.
Sources: [Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/), [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29577586/)

### What does Niacinamide do for dry skin?

Niacinamide helps dry skin by strengthening the skin barrier, increasing hydration, and reducing water loss. It supports ceramide production and helps keep the surface smooth and calm. This ingredient tends to be very well tolerated and is unlikely to irritate dry skin.
Sources: [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/), [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/42108609/)

### Where does this cream go in a skincare routine for dry skin?

This cream goes in your morning routine after a hydrating toner and before your sunscreen, and in your evening routine as your final moisturizing step. It helps keep dry skin soft and smooth by delivering moisture and supporting your skin barrier.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Can I use this cream with retinol, and in what order?

You can use this cream with retinol by applying the cream after your retinol treatment to help soothe and moisturize your dry skin. Using a barrier-supporting moisturizer alongside retinol helps reduce potential irritation and keeps your skin feeling soft and smooth.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### How often should I use this cream?

You can use this moisturizing treatment twice daily as part of your morning and evening routine to keep dry skin hydrated and calm. Daily application helps restore the skin barrier, improve moisture levels, and smooth texture.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for dry skin?

This cream is unlikely to cause breakouts on dry skin because it has a low risk for reactions and features calming ingredients like Centella Asiatica Extract and Panthenol. It also avoids harsh components, making it gentle for daily use.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Can I use this cream around the eyes or on my body?

You can use this moisturizing treatment around your eyes and on your body because it has a gentle formula without harsh ingredients. The panthenol, glycerin, and centella asiatica extract help keep dry skin soft, calm, and well-hydrated.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry skin

- [The Ordinary Natural Moisturizing Factors + HA](https://lovi.care/skincare/nl/p/the-ordinary/natural-moisturizing-factors-ha/for/dry-skin) — Superior fit — €13.02 at Amazon
- [La Roche-Posay Toleriane Ultra Soothing Care](https://lovi.care/skincare/nl/p/la-roche-posay/toleriane-ultra-soothing-repair-moisturizer/for/dry-skin) — High fit — €27.11 at Amazon
- [Anua Heartleaf 78% Soothing Cream](https://lovi.care/skincare/nl/p/anua/heartleaf-78-soothing-cream/for/dry-skin) — High fit — €25.29 at Amazon

## Pairs well with

- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/nl/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — €21.95 at Amazon
- Hydrating Toner: [Dear, Klairs Supple Preparation Unscented Toner](https://lovi.care/skincare/nl/p/dear-klairs/supple-preparation-unscented-toner/for/dry-skin) — Superior fit — €16.89 at Amazon
- SPF: [Purito Daily Soft Touch Sunscreen](https://lovi.care/skincare/nl/p/purito/daily-soft-touch-sunscreen/for/dry-skin) — Superior fit — €20.01 at Amazon

## Where to buy

- Amazon.nl: €19.50 (https://www.amazon.nl/dp/B0CXSM1K2F?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: €24.15 (https://www.lookfantastic.nl/p/numbuzin-no.1-pantothenic-b5-active-cream-80ml/17750370/)
Prices checked 22 Oct – 5 Nov 2026.

## Ingredients

Water, Butylene Glycol, Glycerin, Niacinamide, Cetyl Ethylhexanoate, Dicaprylyl Carbonate, 1,2-Hexanediol, Pentylene Glycol, Vinyl Dimethicone, Centella Asiatica Extract, Caprylyl Methicone, Erythritol, Panthenol, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Dimethiconol, Polymethylsilsesquioxane, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Chlorella Vulgaris Extract, Glucose, Tromethamine, Silica, Fructooligosaccharides, Fructose, Sophora Angustifolia Root Extract, Ethylhexylglycerin, Xanthan Gum, Sodium Phytate, Glyceryl Acrylate Acrylic Acid Copolymer, Caprylic Capric Triglyceride, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Coccinia Indica Fruit Extract, Hydrogenated Lecithin, Ocimum Sanctum Leaf Extract, Tocopherol, Curcuma Longa Root Extract, Aloe Barbadensis Flower Extract, Solanum Melongena Fruit Extract, Decyl Glucoside, Corallina Officinalis Extract, Pantothenic Acid, Polyglyceryl-4 Caprate, Polyglyceryl-6 Caprylate, Camellia Sinensis Leaf Extract, Centella Asiatica Leaf Extract, Cladosiphon Okamuranus Extract, Willow Bark Extract, Houttuynia Cordata Extract, Coffea Arabica Seed Extract Coffee Seed Extract, Bergamot Leaf Extract, Pinus Densiflora Leaf Extract, Alpha-Arbutin, Zinc Pca, Argania Spinosa Kernel Oil, Methyl Diisopropyl Propionamide, Sesamum Indicum Seed Oil, Serenoa Serrulata Fruit Extract, Beta-Sitosterol, Glycyrrhiza Glabra Root Extract Licorice Root Extract
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dry-skin
- France: https://lovi.care/skincare/fr/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dry-skin (this page)
- Spain: https://lovi.care/skincare/es/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dry-skin
- Canada: https://lovi.care/skincare/ca/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dry-skin