NATURIUM Multi-Peptide Moisturizer for oily acne-prone skin
Multi-Peptide Blend
3-O-Ethyl Ascorbic Acid Ethylated Vitamin C
Panthenol Vitamin B5
Squalane
Niacinamide
High
- HighOily Skin Fit
- AverageEffectiveness
- HighSafety
A great choice for oily acne-prone skin; a few moisturizers fit it even better.
This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Highly suitable for your oily skin, this moisturizer contains niacinamide to help regulate oil production and sodium hyaluronate to provide essential hydration without clogging pores. Glycerin and squalane further enhance moisturization, supporting your skin's barrier function.
- While it offers excellent hydration and general skin support, it lacks specific ingredients to directly target acne, blemishes, and breakouts, which are your primary concerns.
- The safety profile is excellent, with no harsh ingredients and the inclusion of soothing components like niacinamide and glycerin, ensuring minimal risk of irritation for your oily skin.
How to apply
- Use this AM and PM routine every day to help clear your skin. Always remember to finish with SPF in the morning.
- Apply the moisturizer after your cleanser and toner, right before your SPF during the day.
- Gently press a small amount into your skin and avoid rubbing to keep pores clear.
- Apply on clean, slightly damp skin to help the product absorb better and control oil.
- Avoid the sensitive eye area and do a simple patch test before your first use.
People Say
★4.5Overall rating based on 600+ reviewsThis moisturizer is highly praised for its lightweight and absorbent texture, making it suitable for oily and combination skin types. It effectively plumps fine lines and improves skin texture, providing a smooth base for makeup. However, users with very dry skin may find it insufficient for their hydration needs and might require additional layering. A small number of reviews mention issues with the pump packaging or experiencing breakouts.
Highlights
Lightweight & Absorbent Mostly Mentioned
- “glides on”
- “sinks effortlessly”
- “non-greasy”
- “drinks it up”
Makeup Compatibility Often Mentioned
- “perfect under makeup”
- “acts like a primer”
- “no pilling”
- “smooth canvas”
Sanitary Packaging Sometimes Noted
- “love the pump”
- “hygienic”
- “airless pump”
- “easy to dispense”
Skin Texture & Plumping Sometimes Noted
- “plumps fine lines”
- “smoother skin”
- “glowy finish”
- “bouncy feel”
Value for Money Sometimes Noted
- “affordable”
- “great ingredients for price”
- “beats high-end”
- “budget friendly”
Not hydrating enough Sometimes Noted
- “too light for dry skin”
- “need more moisture”
- “felt tight later”
- “better for summer”
Breakouts/Irritation Rarely Noted
- “caused cystic acne”
- “tiny red bumps”
- “reaction to niacinamide”
- “broke me out”
Packaging malfunctions Rarely Noted
- “pump arrived broken”
- “stopped pumping”
- “had to cut open”
- “mechanism failed”
Pilling issues Rarely Noted
- “pills with toner”
- “rolled off skin”
- “clumped with serum”
- “didn't layer well”
Small quantity Rarely Noted
- “runs out fast”
- “tube is small”
- “wish it was bigger”
- “finished in weeks”
Sources: lovi.care, naturium.com, target.com, influenster.com, spacenk.com, skinsort.com, and more
Questions and answers
What makes Naturium Multi-Peptide Moisturizer a great fit for oily acne-prone skin?
This moisturizer is a great fit for oily skin because it uses niacinamide to help control excess oil along with lightweight hydration that leaves skin soft without clogging pores. It also has a very safe formula with soothing ingredients that are unlikely to cause irritation. However, because it lacks ingredients that directly target breakouts, oily acne-prone skin needs products containing targeted blemish-fighting ingredients alongside a moisturizer like this.
Which ingredients make this cream a good fit for oily acne-prone skin?
This cream is a great fit for your oily skin because it contains niacinamide to help control excess oil along with sodium hyaluronate, glycerin, and squalane to provide lightweight hydration without clogging your pores. It also has an excellent safety profile with soothing ingredients like niacinamide and glycerin, which means it is unlikely to cause irritation.
What do Peptides do for oily acne-prone skin?
Peptides help oily, acne-prone skin by fighting the bacteria that cause breakouts and calming swelling. These ingredients target acne-causing germs while keeping your skin calm, smooth, and healthy without clogging pores.
What does 3-O-Ethyl Ascorbic Acid do for oily acne-prone skin?
3-O-Ethyl Ascorbic Acid helps support oily acne-prone skin by improving blemishes when formulated in targeted treatments.
Where does this cream go in a skincare routine for oily acne-prone skin?
This moisturizer goes toward the end of your morning and evening routines, right before sunscreen in the morning and after your treatment step at night. It provides essential hydration without clogging pores, though oily acne-prone skin also needs targeted blemish-fighting ingredients to fully address breakouts.
Clinical, Cosmetic and Investigational Dermatology, 2017International Journal of Cosmetic Science, 2020
Can I use this cream with retinol, and in what order?
You can use this moisturizer with retinol by applying the cream after your retinol treatment to help soothe your skin and maintain hydration. Using a barrier-supporting moisturizer alongside retinoids is unlikely to cause irritation and may help reduce dryness and flaking.
How often should I use this cream?
You can use this moisturizing treatment twice daily as part of your morning and evening routines. Daily application helps maintain skin hydration and supports your skin barrier function without clogging pores.
Journal of Cosmetic Dermatology, 2020Health Science Reports, 2021
Can this cream clog pores, cause breakouts or purging for oily acne-prone skin?
This cream is unlikely to clog pores or cause breakouts for oily acne-prone skin. It features a safe formula with soothing ingredients that minimize the risk of irritation, though it does not contain specific acne-fighting ingredients to treat active breakouts.
Can I use this cream around the eyes or on my body?
This moisturizer is safe and gentle enough to use around your eyes and on your body, helping to keep those areas soft and hydrated. Its formula provides great moisture and comfort, though it is primarily designed for facial care.
Is this cream fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol. Cetyl alcohol and stearyl alcohol are fatty alcohols, which soften the skin.
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017A topical serum with a peptide blend showed superior or comparable skin recovery to a moisturizer following fractional CO2 laser and radiofrequency microneedling in Asian subjects.
Dermatology and Therapy, 2026Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers.
Experimental Dermatology, 2003Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation.
Journal of Periodontology, 2009Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream.
Journal of Cosmetic Dermatology, 2022Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment.
American Journal of Clinical Dermatology, 2002Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.
Journal of Cosmetic Dermatology, 2019Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans.
Arzneimittel-Forschung, 2000Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts.
Molecules, 2025Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway.
Antioxidants, 2025Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.
Journal of Cosmetic Dermatology, 2021Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.
The Journal of Investigative Dermatology, 2008Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.
Dermatologic Surgery, 2005
Ingredients
Water, Glycerin, Dimethicone, Jojoba Seed Oil, Squalane, Glyceryl Stearate, Cetyl Alcohol, Niacinamide, Stearyl Alcohol, Palmitoyl Tripeptide-5, Pantolactone, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Hydrolyzed Plukenetia Volubilis Seed Extract, Dunaliella Salina Extract, Sodium Hyaluronate, 3-O-Ethyl Ascorbic Acid, Panthenol, Caryodendron Orinocense Seed Oil, Honokiol, Magnolol, Palmitic Acid, Sorbitan Oleate, Aluminum Octenylsuccinate Starch, Hydroxyacetophenone, Stearic Acid, Acrylamide Sodium Acryloyldimethyltaurate Copolymer, Polyglyceryl-6 Laurate, 1,2-Hexanediol, Boron Nitride, Caprylyl Glycol, Polyglyceryl-10 Oleate, Isohexadecane, Butylene Glycol, Chlorphenesin, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Tocopheryl Acetate, Polysorbate 80, Sorbitan Palmitate, Sodium Hydroxide, Sodium Benzoate, Carbomer, Sodium Lactate, Phenoxyethanol, Polysorbate 20, Citric Acid, Ethylhexylglycerin, Potassium Sorbate
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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