# Murad Retinol Youth Renewal Serum for sensitive skin

**Lovi Fit: Low fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: Concerning.

Page: https://lovi.care/skincare/nl/p/murad/retinol-youth-renewal-serum/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Brand: [Murad](https://lovi.care/skincare/nl/brands/murad)
Category: [Serums and treatments](https://lovi.care/skincare/nl/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A weak match for sensitive skin; the serums alongside fit it better.

## Why this fit

- Offers moderate treatment for aging skin due to retinol and hydroxypinacolone retinoate, which promote cell turnover to minimize fine lines and wrinkles, but can also exacerbate sensitivity and irritation in the short term for your sensitive skin.
- The formulation provides moderate benefits for redness and irritation, though the presence of urea and trehalose helps to soothe and hydrate your normal skin.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/nl/p/murad/retinol-youth-renewal-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/nl/p/murad/retinol-youth-renewal-serum/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/nl/p/murad/retinol-youth-renewal-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/nl/p/murad/retinol-youth-renewal-serum/for/sensitive-skin): Low (this page)
- [Acne-prone skin](https://lovi.care/skincare/nl/p/murad/retinol-youth-renewal-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/nl/p/murad/retinol-youth-renewal-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/nl/p/murad/retinol-youth-renewal-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/nl/p/murad/retinol-youth-renewal-serum/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/nl/p/murad/retinol-youth-renewal-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Retinol, Sodium Hyaluronate, Ceramide Np, Swertia Chirata Extract, Shea Ethyl Esters Butter

## What the research says

- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- Sodium trehalose sulfate decreased transepidermal water loss and increased stratum corneum water content in participants with low stratum corneum water content when applied for 4 weeks compared to placebo. ([Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38606717/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))
- Topical stabilized retinol treatment induced HAS gene expression and increased hyaluronic acid production in human skin in vitro, ex vivo, and in vivo compared to vehicle. ([Archives of Dermatological Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28247017/))
- Topical application of all-trans-retinol induced epidermal thickening and increased retinoid binding protein expression similar to all-trans-retinoic acid in normal human skin, but without causing significant erythema or measurable retinoic acid levels. ([The Journal of Investigative Dermatology, 1995](https://pubmed.ncbi.nlm.nih.gov/7561157/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## Why other serums fit sensitive skin better

- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))

## What reviewers say

Based on a very large amount of data, users with aging or textured skin frequently report visible improvements in fine lines and overall radiance, often praising the formula for being significantly gentler than typical retinols. The "Tri-Active" technology is widely credited for delivering effective anti-aging results without the dryness or irritation commonly associated with vitamin A products.

- Liked: Gentle, non-irritating (mostly mentioned)
- Liked: Improves texture/tone (often mentioned)
- Liked: Reduces fine lines (often mentioned)
- Disliked: High price point (often mentioned)
- Liked: Hydrating formula (sometimes noted)
- Liked: Hygienic packaging (sometimes noted)
- Disliked: Strong fragrance (sometimes noted)
- Disliked: Potential breakouts (rarely noted)
- Disliked: Pump malfunctions (rarely noted)
- Disliked: Slow results (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### Why is Murad Retinol Youth Renewal Serum a weak match for sensitive skin?

This product is a weak match because its retinol and hydroxypinacolone retinoate promote cell turnover that may easily trigger irritation and stinging on sensitive skin. A treatment for this skin needs soothing ingredients like niacinamide and snail secretion filtrate to calm redness while delivering anti-aging benefits safely.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/)

### Which ingredients make this serum a poor fit for sensitive skin?

Retinol and hydroxypinacolone retinoate make this serum a poor fit for sensitive skin because they promote cell turnover, which may easily cause irritation and redness. Sensitive skin needs products with calming ingredients like niacinamide, antioxidants, and skin-repairing components that soothe rather than trigger stinging.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/)

### What does Retinol do for sensitive skin?

Retinol is generally too harsh for sensitive skin and may cause stinging, scaling, and irritation. A product for this skin needs gentle ingredients that smooth and calm without causing redness.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/), [Toxicology Letters, 2003](https://pubmed.ncbi.nlm.nih.gov/14615068/)

### What does Hyaluronic Acid do for sensitive skin?

Hyaluronic acid helps calm and hydrate sensitive skin while supporting the skin barrier to keep it soft and comfortable. Clinical studies show it improves surface moisture and reduces dryness, roughness, and redness without irritation.
Sources: [Journal of Drugs in Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41037531/), [Journal of Cosmetic Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29356277/)

### Where does this serum go in a skincare routine for sensitive skin?

This serum goes in the evening routine after your soothing toner and before your moisturizer. A product of this type needs calming and hydrating ingredients like ceramides and hyaluronic acid to help protect this skin from irritation while smoothing fine lines.

### Can I use this serum with vitamin C, and in what order?

It is best to avoid using this retinol serum at the same time as vitamin C to minimize the likelihood of stinging and redness on sensitive skin. Instead, apply vitamin C in the morning and reserve this treatment for your evening routine. Sensitive skin of this type needs gentle, soothing ingredients like ceramides and hydrating humectants without harsh active ingredients to keep the skin calm and smooth.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/)

### How often should I use this serum?

This serum may be used in the evening as part of your routine, but it is a weak match that can trigger sensitivity and irritation for sensitive skin. A product of this type needs soothing and hydrating ingredients like ceramides, hyaluronic acid, and gentle plant extracts to keep sensitive skin calm and comfortable.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/)

### Can this serum clog pores, cause breakouts or purging for sensitive skin?

This serum may cause irritation and breakouts on sensitive skin because its strong active ingredients speed up skin cell turnover. A product for this skin needs gentle soothing ingredients and extra moisture to keep the skin calm and smooth.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/)

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (citronellol and parfum).

## Alternatives for sensitive skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/nl/p/skinceuticals/c-e-ferulic/for/sensitive-skin) — High fit — €160.00 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/nl/p/neogen-dermalogy/real-vitamin-c-serum/for/sensitive-skin) — High fit — €35.50 at Amazon
- [COSRX The Vitamin C 23 Serum](https://lovi.care/skincare/nl/p/cosrx/the-vitamin-c-23-serum/for/sensitive-skin) — High fit — €19.00 at Amazon

## Routine for sensitive skin

### AM

- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/nl/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/sensitive-skin) — Superior fit — €21.95 at Amazon
- Soothing Toner: [SKIN1004 Centella Asiatica Toning Toner](https://lovi.care/skincare/nl/p/skin1004/centella-asiatica-toning-toner/for/sensitive-skin) — Superior fit — €17.96 at Amazon
- Moisturizer with Sun Protection: [Bioderma Bioderma Photoderm Mineral SPF 50+](https://lovi.care/skincare/nl/p/bioderma/photoderm-mineral-fluide-spf50/for/sensitive-skin) — Superior fit — €19.79 at Amazon

### PM

- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/nl/p/missha/ultra-hyalon-cleansing-cream/for/sensitive-skin) — Superior fit — €11.83 at Amazon
- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/nl/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/sensitive-skin) — Superior fit — €21.95 at Amazon
- Soothing Toner: [SKIN1004 Centella Asiatica Toning Toner](https://lovi.care/skincare/nl/p/skin1004/centella-asiatica-toning-toner/for/sensitive-skin) — Superior fit — €17.96 at Amazon
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/nl/p/peach-and-lily/glass-skin-refining-serum/for/sensitive-skin) — Superior fit — €86.59 at Amazon
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/nl/p/skin1004/centella-cream/for/sensitive-skin) — Superior fit — €19.20 at Amazon

### Weekly

- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/nl/p/missha/ultra-hyalon-cleansing-cream/for/sensitive-skin) — Superior fit — €11.83 at Amazon
- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/nl/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/sensitive-skin) — Superior fit — €21.95 at Amazon
- Enzyme Powder: [By Wishtrend Green Tea & Enzyme Powder Wash](https://lovi.care/skincare/nl/p/by-wishtrend/green-tea-and-enzyme-powder-wash/for/sensitive-skin) — High fit — €20.25 at Amazon
- Nourishing Mask: [Anua Heartleaf 77% Soothing Sheet Mask](https://lovi.care/skincare/nl/p/anua/heartleaf-77-soothing-sheet-mask/for/sensitive-skin) — Superior fit — €24.00 at Amazon
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/nl/p/peach-and-lily/glass-skin-refining-serum/for/sensitive-skin) — Superior fit — €86.59 at Amazon
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/nl/p/skin1004/centella-cream/for/sensitive-skin) — Superior fit — €19.20 at Amazon

## Where to buy

- Notino: €70.50 (https://www.notino.nl/murad/retinol-youth-renewal-gezichtsserum-tegen-huidveroudering/p-16080788/)
Prices checked 29 Oct 2026.

## Ingredients

Water, Cyclopentasiloxane, Isopropyl Palmitate, C14-22 Alcohols, Polymethylsilsesquioxane, Dimethicone, Propanediol, Glyceryl Stearate, Peg-100 Stearate, Shea Ethyl Esters Butter, Retinol, Hydroxypinacolone Retinoate, Ceramide Np, Sodium Hyaluronate, Solanum Lycopersicum Fruit Extract Tomato Fruit Extract, Swertia Chirata Extract, Squalane, Punica Granatum Extract, Tocopheryl Acetate, Glycine Soja Extract Soybean Extract, Urea, Yeast Amino Acids, Trehalose, Inositol, Taurine, Betaine, Glycerin, Caprylic Capric Triglyceride, Dimethyl Isosorbide, Silica, Ethylhexyl Palmitate, Silica Dimethyl Silylate, Butylene Glycol, Lecithin, Ammonium Acryloyldimethyltaurate Vp Copolymer, C12-20 Alkyl Glucoside, Cetyl Palmitate, Laureth-23, Polysorbate 20, Trideceth-6 Phosphate, Synthetic Fluorphlogopite, Phenoxyethanol, Ethylhexylglycerin, Chlorphenesin, Disodium Edta, Sodium Hydroxide, Tris Tetramethylhydroxypiperidinol Citrate, Sodium Benzotriazolyl Butylphenol Sulfonate, Titanium Dioxide Ci 77891, Red 4 Ci 14700, Alpha-Isomethyl Ionone, Citronellol, Parfum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/murad/retinol-youth-renewal-serum/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/murad/retinol-youth-renewal-serum/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/murad/retinol-youth-renewal-serum/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/murad/retinol-youth-renewal-serum/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/murad/retinol-youth-renewal-serum/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/murad/retinol-youth-renewal-serum/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/murad/retinol-youth-renewal-serum/for/sensitive-skin (this page)
- Spain: https://lovi.care/skincare/es/p/murad/retinol-youth-renewal-serum/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/murad/retinol-youth-renewal-serum/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/murad/retinol-youth-renewal-serum/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/murad/retinol-youth-renewal-serum/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/murad/retinol-youth-renewal-serum/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/murad/retinol-youth-renewal-serum/for/sensitive-skin