# Murad Retinal ReSculpt Overnight Treatment for acne-prone skin

**Lovi Fit: Average fit for acne-prone skin.**
Combination Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/nl/p/murad/retinal-resculpt-overnight-treatment/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Brand: [Murad](https://lovi.care/skincare/nl/brands/murad)
Category: [Serums and treatments](https://lovi.care/skincare/nl/best/serums)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for acne-prone skin; other serums fit it better.

## Why this fit

- Offers moderate suitability for your combination skin, as retinal helps regulate cell turnover to address acne and blemishes, while urea and oat kernel extract provide soothing benefits. However, the formula lacks sufficient humectants like glycerin to fully combat potential dryness in certain areas of your combination skin.
- The product is safe for your acne-prone skin, with no harsh ingredients and the inclusion of soothing agents.
- It provides excellent wrinkle reduction and general skincare benefits, supporting your primary goal of managing acne, blemishes, and breakouts.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/nl/p/murad/retinal-resculpt-overnight-treatment/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/nl/p/murad/retinal-resculpt-overnight-treatment/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/nl/p/murad/retinal-resculpt-overnight-treatment/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/nl/p/murad/retinal-resculpt-overnight-treatment/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/nl/p/murad/retinal-resculpt-overnight-treatment/for/acne-prone-skin): Average (this page)
- [Skin with dark spots](https://lovi.care/skincare/nl/p/murad/retinal-resculpt-overnight-treatment/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/nl/p/murad/retinal-resculpt-overnight-treatment/for/mature-skin): Superior
- [Dry sensitive skin](https://lovi.care/skincare/nl/p/murad/retinal-resculpt-overnight-treatment/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/nl/p/murad/retinal-resculpt-overnight-treatment/for/oily-acne-prone-skin): Average

## Key ingredients

Retinal, Squalane, Butyrospermum Parkii Butter Shea Butter, Avena Sativa Kernel Extract Oat Kernel Extract, Urea

## What the research says

- Colloidal oat extracts diminished pro-inflammatory cytokines in vitro and colloidal oat lotion improved skin dryness, scaling, roughness, and itch intensity in healthy female subjects compared to baseline. ([Journal of Drugs in Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25607907/))
- Topically applied Avena sativa and Avena Rhealba oatmeal extracts significantly reduced skin irritation parameters including a* parameter increase and blood flow increase compared to vehicle in 12 healthy individuals subjected to the sodium lauryl sulfate irritation model. ([Skin Pharmacology and Applied Skin Physiology, 2002](https://pubmed.ncbi.nlm.nih.gov/11867969/))
- Colloidal oatmeal induced skin barrier-related gene expression in vitro and showed significant clinical improvements in skin dryness, moisturization, and barrier in 50 healthy female subjects treated with a colloidal oatmeal lotion. ([Journal of Drugs in Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/27272074/))
- A multiple W/O/W emulsion containing Rosmarinus officinalis L., Avena sativa L., and Linum usitatissimum L. extracts showed no irritant, phototoxic, inflammatory, or allergenic potential in human skin models and patch tests, establishing its safety as a cosmetic base. ([Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/34065623/))
- Topical application of a vitamin C-squalene bioconjugate significantly increased epidermal thickness, type III collagen production, and glycosaminoglycans production in human skin explants compared to free vitamin C and vitamin C-palmitate. ([Scientific Reports, 2020](https://pubmed.ncbi.nlm.nih.gov/33037252/))
- Twice daily application of retinaldehyde 0.1% and 0.05% creams for 3 months improved skin texture and hydration and reduced transepidermal water loss in 40 female Korean volunteers, with only the 0.1% cream significantly improving the melanin index. ([Journal of Cosmetic Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29663701/))
- Topical retinaldehyde demonstrated significant antibacterial activity against gram-positive bacteria both in vitro and in vivo, leading to decreased bacterial counts without inducing resistance. ([Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12218231/))
- Topical 0.05% retinaldehyde applied over 1 year significantly increased epidermal thickness of the temple and cutaneous elasticity compared to an emollient control group in 40 aging skin patients. ([Dermatology, 1999](https://pubmed.ncbi.nlm.nih.gov/10473959/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events. ([Lasers in Medical Science, 2025](https://pubmed.ncbi.nlm.nih.gov/41134387/))
- A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells. ([International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39528438/))
- A repair cream containing Rhealba oat plantlets extract, l-ALA-l-GLU dipeptide, and hyaluronic acid provided immediate relief and was judged by doctors as good or very good in 96.8% of cases for wound healing in 2,363 patients following dermatological acts. ([Clinical, Cosmetic and Investigational Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/30519069/))
- Colloidal oat increased the growth rate, metabolism, and lactic acid production of Staphylococcus epidermidis compared to Staphylococcus aureus in vitro, matching clinical increases in lactic acid on dry skin after 6 weeks of lotion use. ([Clinical, Cosmetic and Investigational Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33500646/))
- A dermocosmetic product containing oat plantlet sap and Garcinia mangostana extract reduced retentional and inflammatory acne lesions by 21% and 35% respectively after 2 months in 54 subjects with mild-to-moderate acne. ([Journal of the European Academy of Dermatology and Venereology, 2024](https://pubmed.ncbi.nlm.nih.gov/39051131/))
- Topical 40% urea cream achieved improvement in less time and showed superiority over 12% ammonium lactate lotion in skin roughness, fissure reduction, thickness, and dryness at day 14 in patients treated for moderate to severe xerosis. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/11978141/))
- Topical treatment with K101 achieved a significantly higher mycological cure rate compared to placebo in patients with ≤50% nail involvement (27.2% vs 10.4%), while showing early visible improvements in nail appearance and no safety issues. ([Mycoses, 2012](https://pubmed.ncbi.nlm.nih.gov/22681227/))

## Why other serums fit acne-prone skin better

- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))

## What reviewers say

Users report this treatment effectively targets advanced signs of aging, leading to visibly firmer, smoother, and bouncier skin. It is frequently praised for delivering results on deep wrinkles and sagging without the typical irritation associated with potent retinoids.

- Liked: Visibly smooths texture (mostly mentioned)
- Liked: Firms and lifts (often mentioned)
- Liked: Gentle and non-irritating (often mentioned)
- Disliked: High price point (often mentioned)
- Liked: Fast-acting results (sometimes noted)
- Liked: Pleasant consistency (sometimes noted)
- Disliked: Deceiving packaging (sometimes noted)
- Disliked: Lack of results (rarely noted)
- Disliked: Scent/Fragrance (rarely noted)

## How to apply

- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Murad Retinal ReSculpt work for acne-prone skin?

This treatment works moderately well for acne-prone skin, as retinal helps clear breakouts while oat kernel extract and urea soothe the skin. However, to work best for acne-prone skin, a product of this type needs soothing ingredients, effective hydrators like niacinamide, and antioxidants that balance oil and keep the skin clear without irritation.
Sources: [Journal of Drugs in Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25607907/), [Skin Pharmacology and Applied Skin Physiology, 2002](https://pubmed.ncbi.nlm.nih.gov/11867969/)

### Which ingredients make this treatment a good fit for acne-prone skin?

Retinal helps regulate cell turnover to clear blemishes, while urea and oat kernel extract soothe the skin. To work best for acne-prone skin, a treatment of this type needs ingredients like niacinamide, propolis, and zinc PCA for balanced hydration and oil control.
Sources: [Journal of Drugs in Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25607907/), [Skin Pharmacology and Applied Skin Physiology, 2002](https://pubmed.ncbi.nlm.nih.gov/11867969/)

### What does Retinal do for acne-prone skin?

Retinal helps clear acne-prone skin by reducing blemishes, clogged pores, and redness while improving overall skin texture. Side effects are very uncommon when using this ingredient.
Sources: [International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42572367/), [Clinical and Experimental Dermatology, 1999](https://pubmed.ncbi.nlm.nih.gov/10564319/)

### What does Squalane do for acne-prone skin?

Squalane may help keep acne-prone skin soft and smooth, but peroxidated forms can trigger inflammation in skin cells. For a better fit on acne-prone skin, products need non-clogging, soothing ingredients that balance oil without causing irritation.
Sources: [The Journal of Investigative Dermatology, 2006](https://pubmed.ncbi.nlm.nih.gov/16778793/)

### Where does this treatment go in a skincare routine for acne-prone skin?

This treatment goes in the evening routine after cleansing and before moisturizing. Products of this type work best for this skin when they also include extra hydrating ingredients to keep your skin smooth and comfortable.

### Can I use this treatment with niacinamide, and in what order?

You can use this treatment with niacinamide by applying niacinamide first and following with this treatment once it absorbs, or by alternating nights to keep your skin calm. This type of skin needs a treatment that pairs cell-regulating ingredients like retinal with extra water-attracting ingredients to prevent dryness.

### How often should I use this treatment?

This treatment works for your acne-prone skin, though other products fit it better because it lacks enough hydrators to fully prevent dryness. To get the best results, an acne-prone skin type needs a product of this type that also includes extra hydrators to keep skin comfortable while addressing blemishes.
Sources: [Journal of Drugs in Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25607907/), [Skin Pharmacology and Applied Skin Physiology, 2002](https://pubmed.ncbi.nlm.nih.gov/11867969/)

### Can this treatment clog pores, cause breakouts or purging for acne-prone skin?

This treatment is unlikely to clog pores or cause breakouts on acne-prone skin, as it features soothing ingredients that help calm irritation. However, because it contains retinal to speed up skin cell turnover, you may experience some initial purging as blemishes come to the surface. To work best for acne-prone skin, a product of this type needs lighter hydrating ingredients like hyaluronic acid or glycerin to keep skin balanced without feeling heavy.
Sources: [Skin Pharmacology and Applied Skin Physiology, 2002](https://pubmed.ncbi.nlm.nih.gov/11867969/), [Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/34065623/)

### Is this treatment fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (citronellol and parfum). Cetearyl alcohol and cetyl alcohol are fatty alcohols, which soften the skin.

## Alternatives for acne-prone skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/nl/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/acne-prone-skin) — Superior fit — €10.20 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/nl/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/acne-prone-skin) — Superior fit — €35.80 at Amazon
- [Clinique Fresh Pressed Daily Booster with Pure Vitamin C 10%](https://lovi.care/skincare/nl/p/clinique/fresh-pressed-daily-booster-with-pure-vitamin-c-10/for/acne-prone-skin) — Superior fit — €99.41 at Amazon

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/nl/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — €13.99 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/nl/p/some-by-mi/snail-truecica-miracle-repair-toner/for/acne-prone-skin) — Superior fit — €19.90 at Amazon
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/nl/p/skin1004/centella-cream/for/acne-prone-skin) — Superior fit — €19.20 at Amazon

## Where to buy

No store in Netherlands has a checked price for this product, so the page shows none.

## Ingredients

Water, Diisostearyl Malate, Pentylene Glycol, Polyglyceryl-3 Methylglucose Distearate, Zea Mays Kernel Extract, Squalane, Propanediol, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Glycerin, Cetearyl Alcohol, Glyceryl Ricinoleate, Avena Sativa Kernel Extract Oat Kernel Extract, Butyrospermum Parkii Butter Shea Butter, Retinal, Urea, Yeast Amino Acids, Trehalose, Inositol, Taurine, Betaine, Anigozanthos Flavidus Extract, Phosphatidylcholine, Olea Europaea Leaf Extract Olive Leaf Extract, Mannitol, Ethylhexylglycerin, Dimethyl Isosorbide, Glyceryl Stearate, Sodium Stearoyl Glutamate, Cetyl Alcohol, Hectorite, Xanthan Gum, Sodium Chloride, Polysorbate 60, Sorbitan Isostearate, Leuconostoc Radish Root Ferment Filtrate, Tetrasodium Glutamate Diacetate, Citric Acid, Sodium Benzoate, Chlorphenesin, Potassium Sorbate, Citronellol, Alpha-Isomethyl Ionone, Parfum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/murad/retinal-resculpt-overnight-treatment/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/murad/retinal-resculpt-overnight-treatment/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/murad/retinal-resculpt-overnight-treatment/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/murad/retinal-resculpt-overnight-treatment/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/murad/retinal-resculpt-overnight-treatment/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/murad/retinal-resculpt-overnight-treatment/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/murad/retinal-resculpt-overnight-treatment/for/acne-prone-skin (this page)
- Spain: https://lovi.care/skincare/es/p/murad/retinal-resculpt-overnight-treatment/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/murad/retinal-resculpt-overnight-treatment/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/murad/retinal-resculpt-overnight-treatment/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/murad/retinal-resculpt-overnight-treatment/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/murad/retinal-resculpt-overnight-treatment/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/murad/retinal-resculpt-overnight-treatment/for/acne-prone-skin