# Mixa Urea Cica Repair for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/nl/p/mixa/urea-cica-repair/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Brand: [Mixa](https://lovi.care/skincare/nl/brands/mixa)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/nl/best/moisturizers)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other moisturizers fit it better.

## Why this fit

- Offers moderate suitability for your combination skin, as Glycerin and Hyaluronic Acid provide essential hydration, while Urea and Panthenol support skin barrier repair. However, it lacks sufficient ingredients to optimally control oil in your oily areas.
- The presence of Urea and Allantoin ensures a gentle experience, making it safe for your combination skin without causing irritation.
- This formula is safe for your skin, containing soothing ingredients and avoiding harsh components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/nl/p/mixa/urea-cica-repair/for/oily-skin): Low
- [Dry skin](https://lovi.care/skincare/nl/p/mixa/urea-cica-repair/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/nl/p/mixa/urea-cica-repair/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/nl/p/mixa/urea-cica-repair/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/nl/p/mixa/urea-cica-repair/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/nl/p/mixa/urea-cica-repair/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/nl/p/mixa/urea-cica-repair/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/nl/p/mixa/urea-cica-repair/for/dry-sensitive-skin): Superior
- [Oily acne-prone skin](https://lovi.care/skincare/nl/p/mixa/urea-cica-repair/for/oily-acne-prone-skin): Average

## Key ingredients

Urea, Niacinamide, Hyaluronic Acid, Panthenol, Allantoin

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- Urea is a safe and effective dermatologic therapy with wide-ranging clinical utility for various skin conditions and minimal, non-systemic side effects based on a review of the clinical literature. ([Dermatology Online Journal, 2013](https://pubmed.ncbi.nlm.nih.gov/24314769/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Topical 40% urea cream achieved improvement in less time and showed superiority over 12% ammonium lactate lotion in skin roughness, fissure reduction, thickness, and dryness at day 14 in patients treated for moderate to severe xerosis. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/11978141/))
- Topical treatment with K101 achieved a significantly higher mycological cure rate compared to placebo in patients with ≤50% nail involvement (27.2% vs 10.4%), while showing early visible improvements in nail appearance and no safety issues. ([Mycoses, 2012](https://pubmed.ncbi.nlm.nih.gov/22681227/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two. ([Auris, Nasus, Larynx, 2020](https://pubmed.ncbi.nlm.nih.gov/32067777/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))

## How to apply

- Use this moisturizer in your AM and PM routine every day to control shine. Always pair with SPF in the morning.
- Apply this moisturizer after your cleanser and toner, right before your morning SPF.
- Gently press a small amount of the moisturizer into your skin and avoid harsh rubbing. Let it ⏳absorb for a minute.
- Apply the moisturizer on slightly damp skin to help it lock in moisture better. This keeps your combination skin balanced.
- Avoid the eye area when applying the moisturizer. Do a patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Mixa Urea Cica Repair work for combination skin?

Mixa Urea Cica Repair offers moderate suitability for combination skin because glycerin and hyaluronic acid provide essential hydration while urea and panthenol support skin barrier repair, though it lacks sufficient ingredients to optimally control oil in your oily areas. To work best for combination skin, a moisturizer of this type needs ingredients that reduce oily shine while providing balanced hydration without irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Which ingredients make this cream a good fit for combination skin?

Glycerin and Hyaluronic Acid provide essential hydration, while Urea and Panthenol help repair your skin barrier. However, a moisturizing treatment for combination skin also needs ingredients to control oil in oily areas and reduce shine.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### What does Urea do for combination skin?

Urea is a poor fit for combination skin because it is designed for very dry, scaly skin and may overwhelm oily areas. Combination skin needs lighter, balancing hydrators and gentle exfoliants that provide moisture without feeling heavy.

### What does Niacinamide do for combination skin?

Niacinamide helps balance oily areas by reducing excess shine and pore size while keeping dry patches hydrated and smooth. It also works to calm redness and even out skin tone, making it very suitable for combination skin.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Where does it go in a skincare routine for combination skin?

This moisturizer goes in the morning routine after a hydrating toner and before sunscreen, and in the evening routine after cleansing and any treatment. For combination skin, a product of this type also needs ingredients to control oil in oily areas.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this cream with retinol, and in what order?

You can use this cream with retinol by applying the retinol first and following with the cream to help keep your skin calm and moisturized. This type of product for combination skin needs to include ingredients that help control oil in oily areas while keeping dry areas soft.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### How often should I use it?

You can use this moisturizing treatment twice daily to help keep your skin hydrated and support your skin barrier. Regular daily application of this type of formula improves overall moisture and texture.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Skin Pharmacology and Physiology, 2026](https://pubmed.ncbi.nlm.nih.gov/41231732/)

### Can this cream clog pores, cause breakouts or purging for combination skin?

This cream is unlikely to clog pores or cause breakouts on your combination skin because it avoids harsh components and relies on soothing ingredients like urea and allantoin. However, because it lacks sufficient ingredients to optimally control oil in your oily areas, combination skin still needs light hydration and oil-balancing ingredients like niacinamide or salicylic acid.

### Can I use it around the eyes or on my body?

You can safely use this moisturizing treatment on your body and around your eyes, as it features soothing ingredients that are gentle and unlikely to cause irritation. To work best for your combination skin, this type of product also needs ingredients that help control oil in your oily areas.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for combination skin

- [The Ordinary Natural Moisturizing Factors + HA](https://lovi.care/skincare/nl/p/the-ordinary/natural-moisturizing-factors-ha/for/combination-skin) — High fit — €13.02 at Amazon
- [Anua Heartleaf 78% Soothing Cream](https://lovi.care/skincare/nl/p/anua/heartleaf-78-soothing-cream/for/combination-skin) — High fit — €25.29 at Amazon
- [ANUA Heartleaf 70% Soothing Cream](https://lovi.care/skincare/nl/p/anua/heartleaf-70-soothing-cream/for/combination-skin) — High fit — €25.29 at Amazon

## Pairs well with

- Cleanser: [Dr. Althea Amino Acid Gentle Bubble Cleanser](https://lovi.care/skincare/nl/p/dr-althea/amino-acid-gentle-bubble-cleanser/for/combination-skin) — Superior fit — €16.50 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/nl/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — €36.00 at Amazon
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/nl/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/combination-skin) — Superior fit — €33.70 at Amazon

## Where to buy

No store in Netherlands has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Urea, Cetearyl Alcohol, Butyrospermum Parkii Butter Shea Butter, Caprylic Capric Triglyceride, Cetearyl Glucoside, Dimethicone, Panthenol, Allantoin, Hyaluronic Acid, Tocopherol, Phenoxyethanol, Ethylhexylglycerin, Carbomer, Sodium Hydroxide
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/mixa/urea-cica-repair/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/mixa/urea-cica-repair/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/mixa/urea-cica-repair/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/mixa/urea-cica-repair/for/combination-skin
- France: https://lovi.care/skincare/fr/p/mixa/urea-cica-repair/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/mixa/urea-cica-repair/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/mixa/urea-cica-repair/for/combination-skin (this page)
- Spain: https://lovi.care/skincare/es/p/mixa/urea-cica-repair/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/mixa/urea-cica-repair/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/mixa/urea-cica-repair/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/mixa/urea-cica-repair/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/mixa/urea-cica-repair/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/mixa/urea-cica-repair/for/combination-skin