# MISSHA Time Revolution Night Repair Probio Ampoule for dry skin

**Lovi Fit: High fit for dry skin.**
Dry Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/nl/p/missha/time-revolution-night-repair-probio-ampoule/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Brand: [MISSHA](https://lovi.care/skincare/nl/brands/missha)
Category: [Serums and treatments](https://lovi.care/skincare/nl/best/serums)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for dry skin; a few serums fit it even better.

## Why this fit

- This formulation offers high suitability for your dry skin, as Bifida Lysate Ferment and Sodium Hyaluronate work to deeply hydrate and support your skin barrier, addressing dryness and flakiness. Glycerin and Squalane further enhance this by providing essential humectant and emollient actions, leaving your skin feeling smoother and more comfortable.
- The presence of Niacinamide contributes to evening skin tone and improving overall skin resilience, complementing the primary hydrating benefits.
- The product is safe for your dry skin, with no risks of irritation due to the absence of harsh ingredients and the inclusion of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/nl/p/missha/time-revolution-night-repair-probio-ampoule/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/nl/p/missha/time-revolution-night-repair-probio-ampoule/for/dry-skin): High (this page)
- [Combination skin](https://lovi.care/skincare/nl/p/missha/time-revolution-night-repair-probio-ampoule/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/nl/p/missha/time-revolution-night-repair-probio-ampoule/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/nl/p/missha/time-revolution-night-repair-probio-ampoule/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/nl/p/missha/time-revolution-night-repair-probio-ampoule/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/nl/p/missha/time-revolution-night-repair-probio-ampoule/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/nl/p/missha/time-revolution-night-repair-probio-ampoule/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/nl/p/missha/time-revolution-night-repair-probio-ampoule/for/oily-acne-prone-skin): Average

## Key ingredients

Bifida Lysate Ferment, Niacinamide, Sodium Hyaluronate, Probio Lactobacillus Complex, Panthenol

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Topical application of Bifida Ferment Lysate strengthens the skin barrier function by upregulating barrier and antimicrobial peptide genes, exhibiting strong antioxidant properties, and decreasing inflammatory cytokine secretion in vitro. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Probiotic-derived lotion successfully reduced inflammatory acne lesion counts and erythema index comparably to 2.5% benzoyl peroxide in patients with mild-to-moderate acne vulgaris, while causing fewer side effects. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35384257/))
- Topical application of Lactobacillus plantarum-GMNL6 enhanced collagen synthesis and SPTSSA gene expression while reducing melanin synthesis, Staphylococcus aureus biofilm, and Cutibacterium acnes proliferation, leading to clinical improvements in skin moisture, color, spots, wrinkles, UV spots, and porphyrins in human volunteers. ([International Journal of Medical Sciences, 2021](https://pubmed.ncbi.nlm.nih.gov/33526970/))
- Lactobacillus plantarum extracellular vesicles modulated extracellular matrix related gene expression in vitro and suppressed wrinkle formation and pigmentation in clinical trials. ([Current Issues in Molecular Biology, 2022](https://pubmed.ncbi.nlm.nih.gov/35723322/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))

## What reviewers say

This ampoule is frequently praised for delivering a 'glass skin' effect overnight, making dry and mature skin appear plump, hydrated, and glowing. A very large amount of data suggests that while it's a highly effective and affordable alternative to luxury serums, the high concentration of fermented ingredients may cause breakouts in individuals with fungal acne or sensitivities.

- Liked: Instant Glow (mostly mentioned)
- Liked: Deep Hydration (often mentioned)
- Liked: Lightweight Texture (often mentioned)
- Liked: Texture Improvement (sometimes noted)
- Liked: Value for Money (sometimes noted)
- Disliked: Breakouts & Reactions (sometimes noted)
- Disliked: Fragrance & Oils (sometimes noted)
- Disliked: Dropper Issues (rarely noted)
- Disliked: Ineffective for Some (rarely noted)
- Disliked: Sticky Residue (rarely noted)

## How to apply

- Apply this serum PM, starting 3×/week and working up to daily use as your skin adjusts.
- Place the serum after cleansing and toner, but right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on slightly damp skin to help lock in extra moisture.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes MISSHA Time Revolution Night Repair Probio Ampoule a great fit for dry skin?

This treatment is a great fit because Bifida Lysate Ferment and Sodium Hyaluronate deeply hydrate and support your skin barrier, helping to clear up dryness and flakiness. Glycerin and Squalane keep your dry skin feeling smoother and more comfortable, while soothing components mean the product is unlikely to cause irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for dry skin?

Bifida Lysate Ferment, Sodium Hyaluronate, Glycerin, and Squalane make this serum a great fit because they deeply hydrate and support your skin barrier, helping to relieve dryness and flakiness while leaving your skin feeling smoother and more comfortable. Niacinamide and panthenol further help improve skin resilience and moisture.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### What does Bifida Ferment Lysate do for dry skin?

Bifida Ferment Lysate helps dry skin by strengthening the skin barrier and keeping it well hydrated. It also helps calm irritation and protects against everyday stress.
Sources: [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/), [Scientific Reports, 2023](https://pubmed.ncbi.nlm.nih.gov/37803101/)

### What does Niacinamide do for dry skin?

Niacinamide helps dry skin by strengthening the skin barrier, increasing hydration, and reducing water loss. It supports ceramide production and helps keep the surface smooth and calm. This ingredient tends to be very well tolerated and is unlikely to irritate dry skin.
Sources: [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/), [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/42108609/)

### Where does this serum go in a skincare routine for dry skin?

This treatment goes in your evening routine after cleansing and before your moisturizer. Using it at night is simple and keeps your skin safe from extra sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this treatment with retinol by applying this serum first to deeply hydrate your dry skin, followed by your retinol product. This approach helps minimize potential irritation while supporting your skin barrier against dryness.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### How often should I use this serum?

This treatment is great for your dry skin and is meant to be used in the evening as part of your routine. It deeply hydrates, soothes, and supports your skin barrier without causing irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36798538/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can this serum clog pores, cause breakouts or purging for dry skin?

This treatment may occasionally cause breakouts or reactions for dry skin, as some reviewers have experienced, though it is unlikely to irritate since it avoids harsh ingredients and includes soothing components.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/nl/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/dry-skin) — Superior fit — €10.20 at Amazon
- [ma:nyo Bifida Biome Complex Ampoule](https://lovi.care/skincare/nl/p/ma-nyo/bifida-biome-complex-ampoule/for/dry-skin) — Superior fit — €25.00 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/nl/p/augustinus-bader/the-serum/for/dry-skin) — Superior fit — €474.90 at Amazon

## Pairs well with

- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/nl/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — €21.95 at Amazon
- Hydrating Toner: [Dear, Klairs Supple Preparation Unscented Toner](https://lovi.care/skincare/nl/p/dear-klairs/supple-preparation-unscented-toner/for/dry-skin) — Superior fit — €16.89 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/nl/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/dry-skin) — Superior fit — €48.84 at Amazon

## Where to buy

- Amazon.nl: €69.20 (https://www.amazon.nl/dp/B0BXDJVW78?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- Notino: €53.90 (https://www.notino.nl/missha/time-revolution-night-repair-ampoule-5x-intensieve-nachtverzorging-met-anti-rimpel-werking/p-16145762/)
Prices checked 17 Oct – 5 Nov 2026.

## Ingredients

Bifida Lysate Ferment, Butylene Glycol, Glycerin, Propanediol, Betaine, Water, Niacinamide, Pentylene Glycol, 1,2-Hexanediol, Diethoxyethyl Succinate, Chondrus Crispus Extract, Squalane, Panthenol, Polyglyceryl-10 Laurate, Saccharum Officinarum Extract, Hydrogenated Lecithin, Carbomer, Tromethamine, Xanthan Gum, Polyquaternium-51, Ethylhexylglycerin, Adenosine, Dextrin, Theobroma Cacao Extract, Beta Vulgaris Root Extract, Brassica Oleracea Capitata Leaf Extract, Daucus Carota Sativa Root Extract Carrot Root Extract, Solanum Melongena Fruit Extract, Blueberry Fruit Extract, Bergamot Oil Fruit, Disodium Edta, Sodium Hyaluronate, Lactobacillus Soybean Extract Ferment, Leuconostoc Radish Root Ferment Filtrate, Bifida Ferment Filtrate, Lactobacillus Ferment, Lactobacillus Lysate Ferment, Lactobacillus Acerola Cherry Ferment, Lactobacillus Punica Granatum Extract Fruit Ferment, Pelargonium Graveolens Oil Flower, Helianthus Annuus Seed Oil Sunflower Seed Oil, Citrus Aurantium Dulcis Peel Oil, Lavandula Angustifolia Oil Lavender Oil, Lupinus Albus Seed Extract, Aspergillus Ferment, Swiftlet Nest Extract, Anthemis Nobilis Oil Flower, Sandalwood Oil, Tocopherol, Ceramide Np, Cholesterol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/missha/time-revolution-night-repair-probio-ampoule/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/missha/time-revolution-night-repair-probio-ampoule/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/missha/time-revolution-night-repair-probio-ampoule/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/missha/time-revolution-night-repair-probio-ampoule/for/dry-skin
- France: https://lovi.care/skincare/fr/p/missha/time-revolution-night-repair-probio-ampoule/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/missha/time-revolution-night-repair-probio-ampoule/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/missha/time-revolution-night-repair-probio-ampoule/for/dry-skin (this page)
- Spain: https://lovi.care/skincare/es/p/missha/time-revolution-night-repair-probio-ampoule/for/dry-skin
- Canada: https://lovi.care/skincare/ca/p/missha/time-revolution-night-repair-probio-ampoule/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/missha/time-revolution-night-repair-probio-ampoule/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/missha/time-revolution-night-repair-probio-ampoule/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/missha/time-revolution-night-repair-probio-ampoule/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/missha/time-revolution-night-repair-probio-ampoule/for/dry-skin