# MiamiMD Age Defying Lift & Firm Cream for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/nl/p/miamimd/age-defying-lift-and-firm-cream/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Brand: [MiamiMD](https://lovi.care/skincare/nl/brands/miamimd)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/nl/best/moisturizers)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other moisturizers fit it better.

## Why this fit

- Offers moderate benefits for your combination skin, with sodium hyaluronate and glycerin providing excellent hydration and ceramides supporting barrier repair, though it does not specifically address oily shine.
- The inclusion of palmitoyl tripeptide-5 and acetyl hexapeptide-8 contributes to firming effects, which are beneficial for overall skin health.
- The product is safe for your combination skin, as it contains no harsh ingredients that would cause irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/nl/p/miamimd/age-defying-lift-and-firm-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/nl/p/miamimd/age-defying-lift-and-firm-cream/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/nl/p/miamimd/age-defying-lift-and-firm-cream/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/nl/p/miamimd/age-defying-lift-and-firm-cream/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/nl/p/miamimd/age-defying-lift-and-firm-cream/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/nl/p/miamimd/age-defying-lift-and-firm-cream/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/nl/p/miamimd/age-defying-lift-and-firm-cream/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/nl/p/miamimd/age-defying-lift-and-firm-cream/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/nl/p/miamimd/age-defying-lift-and-firm-cream/for/oily-acne-prone-skin): Average

## Key ingredients

Palmitoyl Tripeptide-1, Acetyl Hexapeptide-8, Sodium Hyaluronate, Ceramide Ng, Jojoba Seed Oil

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Supramolecular collagen nanoparticles composed of lactoferrin, recombinant human collagen, and palmitoyl tripeptide-5 improved transdermal efficiency by 69.90% and demonstrated moisturizing, whitening, wrinkle reduction, and firming effects. ([Colloids and Surfaces. B, Biointerfaces, 2025](https://pubmed.ncbi.nlm.nih.gov/39383579/))
- Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group. ([American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/))
- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))
- A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo. ([Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/))
- Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/))
- Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components. ([International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42683869/))
- Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/))
- Daily topical acetyl hexapeptide-8 showed a trend toward a longer time until return to baseline Jankovic Blepharospasm Rating Scale scores compared to placebo (3.7 months vs. 3.0 months) in 24 patients with blepharospasm receiving botulinum toxin therapy. ([European Journal of Neurology, 2013](https://pubmed.ncbi.nlm.nih.gov/23146065/))
- Argireline applied twice daily for 4 weeks achieved a total anti-wrinkle efficiency of 48.9% and notably reduced wrinkle depth compared to placebo in Chinese subjects. ([Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Clay jojoba oil facial masks reduced total skin lesions by a mean of 54% after 6 weeks in 133 participants with acne-prone, lesioned skin and mild acne compared to baseline. ([Forschende Komplementarmedizin, 2012](https://pubmed.ncbi.nlm.nih.gov/22585103/))
- Topical application of jojoba wax reduced LPS-induced secretion of IL-6, IL-8, and TNFα by approximately 30% and increased the synthesis of pro-collagen III and hyaluronic acid compared to untreated skin in an ex-vivo human skin organ culture model. ([Frontiers in Pharmacology, 2024](https://pubmed.ncbi.nlm.nih.gov/38344180/))
- Topical jojoba oil application in male mice decreased exercise-induced pro-inflammatory gene expression (Il-1b and Il-6 in soleus, Il-1b in gastrocnemius) compared to untreated exercised mice. ([Biomolecules, 2025](https://pubmed.ncbi.nlm.nih.gov/41154623/))

## What reviewers say

Based on limited data, this product is frequently praised for its lightweight, non-greasy texture and its ability to hydrate and improve the appearance of fine lines and skin texture. Some users report a lack of visible results for deeper wrinkles or sagging skin, and a few express concerns about the product's price and company subscription policies.

- Liked: Lightweight texture (often mentioned)
- Liked: Hydrating and smoothing (sometimes noted)
- Liked: Improves fine lines (sometimes noted)
- Disliked: Lack of results (sometimes noted)
- Disliked: High price (rarely noted)
- Disliked: Subscription issues (rarely noted)

## How to apply

- Use this moisturizer in your AM and PM routine every day to control shine. Always pair with SPF in the morning.
- Apply this moisturizer after your cleanser and toner, right before your morning SPF.
- Gently press a small amount of the moisturizer into your skin and avoid harsh rubbing. Let it ⏳absorb for a minute.
- Apply the moisturizer on slightly damp skin to help it lock in moisture better. This keeps your combination skin balanced.
- Avoid the eye area when applying the moisturizer. Do a patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does MiamiMD Age Defying Lift & Firm Cream work for combination skin?

MiamiMD Age Defying Lift & Firm Cream works moderately well for combination skin, offering good hydration and firming peptides while leaving oily shine unaddressed. A product of this type needs ingredients that target hydration and brightness, along with soothing agents to reduce oily shine without causing irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Colloids and Surfaces. B, Biointerfaces, 2025](https://pubmed.ncbi.nlm.nih.gov/39383579/)

### Which ingredients make this cream a good fit for combination skin?

Sodium hyaluronate and glycerin help provide great hydration, while ceramides support your skin barrier without causing irritation. To be a better fit for this skin type, a product of this kind also needs brightening ingredients that reduce oily shine.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/)

### What does Palmitoyl Tripeptide-1 do for combination skin?

Palmitoyl tripeptide-1 helps smooth fine lines and supports firmness in combination skin when used as part of an anti-aging routine. Studies show that ingredients like this peptide can improve overall skin texture and boost collagen levels when applied consistently over time.
Sources: [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/), [International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42683869/)

### What does Argireline do for combination skin?

Argireline helps smooth out lines and keeps combination skin feeling soft when applied twice daily. This ingredient may reduce wrinkle depth and improve overall skin texture, though its absorption through the skin is quite low.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/)

### Where does this cream go in a skincare routine for combination skin?

This moisturizing treatment goes in the evening routine after cleansing and before your moisturizer. It is safe for your skin, though a product for combination skin also needs ingredients that control oily shine.

### Can I use this cream with retinol, and in what order?

You can use this cream with retinol, and applying it after your retinol helps keep your skin calm by reducing dryness and irritation. A moisturizer of this type used with retinol needs barrier-restoring ceramides and soothing hydration to support skin comfort.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this cream?

You can use this moisturizing treatment twice daily to keep your skin hydrated and smooth. Daily application helps improve skin moisture and firmness while remaining gentle on your skin.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for combination skin?

This cream is unlikely to clog pores or cause breakouts for combination skin, as it has a safe make-up with no harsh ingredients that would cause irritation. However, a cream of this type also needs oil-controlling ingredients to properly balance shiny zones.

### Can I use this cream around the eyes or on my body?

You can use this moisturizing treatment around the eyes and on the body, as it has a safe profile with no harsh ingredients that would cause irritation. Regular application of anti-ageing creams containing hyaluronic acid and peptides is supported by studies showing they safely reduce wrinkles in the thin periorbital area and improve overall skin texture.
Sources: [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37896378/), [Colloids and Surfaces. B, Biointerfaces, 2025](https://pubmed.ncbi.nlm.nih.gov/39383579/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [The Ordinary Natural Moisturizing Factors + HA](https://lovi.care/skincare/nl/p/the-ordinary/natural-moisturizing-factors-ha/for/combination-skin) — High fit — €13.02 at Amazon
- [Anua Heartleaf 78% Soothing Cream](https://lovi.care/skincare/nl/p/anua/heartleaf-78-soothing-cream/for/combination-skin) — High fit — €25.29 at Amazon
- [ANUA Heartleaf 70% Soothing Cream](https://lovi.care/skincare/nl/p/anua/heartleaf-70-soothing-cream/for/combination-skin) — High fit — €25.29 at Amazon

## Pairs well with

- Cleanser: [Dr. Althea Amino Acid Gentle Bubble Cleanser](https://lovi.care/skincare/nl/p/dr-althea/amino-acid-gentle-bubble-cleanser/for/combination-skin) — Superior fit — €16.50 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/nl/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — €36.00 at Amazon
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/nl/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/combination-skin) — Superior fit — €33.70 at Amazon

## Where to buy

No store in Netherlands has a checked price for this product, so the page shows none.

## Ingredients

Water, Jojoba Seed Oil, Glycerin, Carbomer, Phenoxyethanol, Dimethicone, Prunus Amygdalus Dulcis Oil, Triethanolamine, Sodium Polyacrylate, Butylene Glycol, Dimethiconol, Sodium Lauroyl Lactylate, Diethanolamine, Laureth-4, Laureth-23, Sodium Hyaluronate, Ceramide Np, Palmitoyl Tripeptide-5, Caprylyl Glycol, Polysorbate 20, Phytosphingosine, Cholesterol, Ceramide Ap, Potassium Sorbate, Xanthan Gum, Tocopherol, Hexylene Glycol, Dextran, Acetyl Hexapeptide-8, Trifluoroacetyl Tripeptide-2, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide Eop
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/miamimd/age-defying-lift-and-firm-cream/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/miamimd/age-defying-lift-and-firm-cream/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/miamimd/age-defying-lift-and-firm-cream/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/miamimd/age-defying-lift-and-firm-cream/for/combination-skin
- France: https://lovi.care/skincare/fr/p/miamimd/age-defying-lift-and-firm-cream/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/miamimd/age-defying-lift-and-firm-cream/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/miamimd/age-defying-lift-and-firm-cream/for/combination-skin (this page)
- Spain: https://lovi.care/skincare/es/p/miamimd/age-defying-lift-and-firm-cream/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/miamimd/age-defying-lift-and-firm-cream/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/miamimd/age-defying-lift-and-firm-cream/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/miamimd/age-defying-lift-and-firm-cream/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/miamimd/age-defying-lift-and-firm-cream/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/miamimd/age-defying-lift-and-firm-cream/for/combination-skin