# Medik8 Liquid Peptides for dry sensitive skin

**Lovi Fit: Average fit for dry sensitive skin.**
Dry Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/nl/p/medik8/liquid-peptides/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Brand: [Medik8](https://lovi.care/skincare/nl/brands/medik8)
Category: [Serums and treatments](https://lovi.care/skincare/nl/best/serums)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry sensitive skin; other serums fit it better.

## Why this fit

- Offers moderate hydration for your dry and flaky skin, as glycerin and hyaluronic acid draw moisture into the skin to improve its texture and suppleness.
- The peptides in the formula, such as Acetyl Hexapeptide-8 and Palmitoyl Tripeptide-1, provide excellent plumping and firming benefits, enhancing overall skin appearance.
- The product is safe for your dry and sensitive skin, with no risks of irritation due to the absence of harsh or prohibited ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/nl/p/medik8/liquid-peptides/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/nl/p/medik8/liquid-peptides/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/nl/p/medik8/liquid-peptides/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/nl/p/medik8/liquid-peptides/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/nl/p/medik8/liquid-peptides/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/nl/p/medik8/liquid-peptides/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/nl/p/medik8/liquid-peptides/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/nl/p/medik8/liquid-peptides/for/dry-sensitive-skin): Average (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/nl/p/medik8/liquid-peptides/for/oily-acne-prone-skin): Average

## Key ingredients

Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group. ([American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/))
- Argireline applied twice daily for 4 weeks achieved a total anti-wrinkle efficiency of 48.9% and notably reduced wrinkle depth compared to placebo in Chinese subjects. ([Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/))
- Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/))
- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))
- Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/))
- Daily topical acetyl hexapeptide-8 showed a trend toward a longer time until return to baseline Jankovic Blepharospasm Rating Scale scores compared to placebo (3.7 months vs. 3.0 months) in 24 patients with blepharospasm receiving botulinum toxin therapy. ([European Journal of Neurology, 2013](https://pubmed.ncbi.nlm.nih.gov/23146065/))
- A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo. ([Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/))
- Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components. ([International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42683869/))

## What reviewers say

Users consistently praise this serum as a "Botox in a bottle" alternative that delivers immediate hydration and visible plumping, particularly for fine lines on the forehead and around the eyes. It is widely celebrated for its ability to smooth skin texture and restore bounce to dry or mature skin without causing irritation, making it a staple for those targeting early to advanced signs of aging.

- Liked: Deeply hydrating (mostly mentioned)
- Liked: Elegant, lightweight texture (often mentioned)
- Liked: Visibly plumps and smooths (often mentioned)
- Disliked: High price point (often mentioned)
- Liked: Gentle and non-irritating (sometimes noted)
- Disliked: Packaging fragility (sometimes noted)
- Disliked: Results require patience (rarely noted)
- Disliked: Slight tackiness (rarely noted)

## How to apply

- Use this PM routine for your evening skincare. Start using the serum 3 times a week and increase to daily use if your skin feels comfortable.
- Apply the serum after cleansing and toner, but right before your moisturizer. This step locks in deep hydration for dry skin.
- Gently press 2-3 drops of the serum into your skin using your palms. Let it absorb completely for a minute ⏱ before applying your next product.
- Since your skin is sensitive, apply the serum on completely dry skin for better tolerance and less irritation.
- Avoid the sensitive eye area during application. Always do a patch test before your first use to ensure your skin reacts well.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Medik8 Liquid Peptides work for dry sensitive skin?

Medik8 Liquid Peptides works moderately well for your dry sensitive skin, offering hydration and firming benefits with very little risk of irritation. A treatment for this skin type needs high suitability with maximum beneficial ingredients that hydrate and protect, along with ceramides, multiple forms of vitamin C, and optimal textures and pH levels to enhance appearance and resilience against environmental stressors.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/)

### Which ingredients make this serum a good fit for dry sensitive skin?

Glycerin and hyaluronic acid help make this serum a good fit by drawing moisture into your dry skin to improve its texture and smoothness. Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, and Palmitoyl Tetrapeptide-7 also provide great plumping and firming benefits without irritation. To fit this skin type even better, a treatment of this type needs extra nourishing and barrier-supporting ingredients like ceramides and soothing vitamins.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/)

### What does Argireline do for dry sensitive skin?

Argireline helps smooth fine lines and keeps skin soft, but dry sensitive skin needs added moisture and soothing ingredients to feel fully comfortable. It is unlikely to cause irritation when used as directed, yet a product of this type for dry sensitive skin needs rich hydrators and calming agents to prevent dryness and protect the skin barrier.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/40565185/)

### What does Palmitoyl Tripeptide-1 do for dry sensitive skin?

Palmitoyl tripeptide-1 helps firmness and smooths fine lines, and it is best paired with a gentle moisturizer to keep dry sensitive skin comfortable. Because it supports collagen, it may improve skin texture over time while remaining gentle enough for daily use.
Sources: [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/), [International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42683869/)

### Where does it go in a skincare routine for dry sensitive skin?

Medik8 Liquid Peptides goes in the evening routine after your toner and before your moisturizer. This product type needs gentle hydrating ingredients like glycerin and hyaluronic acid, along with soothing plant extracts, to keep dry and sensitive skin calm and comfortable.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying this treatment first in your evening routine, followed by your moisturizer and then your retinol. This product is unlikely to irritate dry and sensitive skin because it lacks harsh or prohibited ingredients.

### How often should I use it?

Use this treatment in your evening routine, applying it after your toner and before your moisturizer. Dry and sensitive skin of this type needs a formula rich in gentle hydrating ingredients like hyaluronic acid and glycerin, alongside soothing moisturizers that strengthen the skin barrier without causing irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/)

### Can this serum clog pores, cause breakouts or purging for dry sensitive skin?

Medik8 Liquid Peptides is unlikely to clog pores, cause breakouts, or lead to purging on dry sensitive skin. The formula is safe for this skin type and carries no risks of irritation due to the absence of harsh ingredients.

### Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry sensitive skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/nl/p/skinceuticals/c-e-ferulic/for/dry-sensitive-skin) — Superior fit — €160.00 at Amazon
- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/nl/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/dry-sensitive-skin) — Superior fit — €10.20 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/nl/p/augustinus-bader/the-serum/for/dry-sensitive-skin) — Superior fit — €474.90 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/nl/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — €15.00 at Amazon
- Soothing Toner: [SKIN1004 Centella Asiatica Toning Toner](https://lovi.care/skincare/nl/p/skin1004/centella-asiatica-toning-toner/for/dry-sensitive-skin) — Superior fit — €17.96 at Amazon
- Moisturizer with Sun Protection: [d'Alba UVessence Mild Waterfull Sun Cream SPF 50](https://lovi.care/skincare/nl/p/d-alba/uvessence-mild-waterfull-sun-cream-spf-50/for/dry-sensitive-skin) — Superior fit — €16.75 at Amazon

## Where to buy

- Amazon.nl: €98.05 (https://www.amazon.nl/dp/B0DSJNWVV6?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- Notino: €51.50 (https://www.notino.nl/medik8/liquid-peptides-anti-rimpel-serum/p-16088423/)
- Lookfantastic: €100.00 (https://www.lookfantastic.nl/p/medik8-liquid-peptides-advanced-mp-30ml/15826874/)
Prices checked 10 Oct – 6 Nov 2026.

## Ingredients

Water, Glycerin, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Carbomer, Phenoxyethanol, Ethylhexylglycerin, Hyaluronic Acid, Lecithin, Caprylyl Glycol, Disodium Edta, Citric Acid
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medik8/liquid-peptides/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medik8/liquid-peptides/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/medik8/liquid-peptides/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/medik8/liquid-peptides/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/medik8/liquid-peptides/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/medik8/liquid-peptides/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/medik8/liquid-peptides/for/dry-sensitive-skin (this page)
- Spain: https://lovi.care/skincare/es/p/medik8/liquid-peptides/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/medik8/liquid-peptides/for/dry-sensitive-skin
- Australia: https://lovi.care/skincare/au/p/medik8/liquid-peptides/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/medik8/liquid-peptides/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medik8/liquid-peptides/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medik8/liquid-peptides/for/dry-sensitive-skin