MEDIHEAL AGE-R for sensitive skin
Glutathione
Collagen
Peptides
Average
- HighNormal Skin Fit
- AverageEffectiveness
- HighSafety
Works for sensitive skin; other serums fit it better.
This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate plumping and firming for your normal skin due to collagen and peptides, which also provide soothing effects for redness and irritation.
- The presence of glutathione further supports general skincare benefits, enhancing overall skin health.
- The product is safe for your sensitive skin as it lacks harsh or prohibited ingredients.
How to apply
- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
People Say
★4.4Overall rating based on 12.5k+ reviewsBased on a very large amount of data, users frequently achieve a 'glass skin' appearance and improved facial contouring, with many reporting enhanced product absorption and a more radiant complexion. While effective for dullness and mild sagging, results are highly dependent on consistent daily use, which some users find difficult to maintain. The device is also noted for improving skin texture and reducing pore visibility.
Highlights
Enhanced absorption Mostly Mentioned
- “products absorb instantly”
- “skincare feels supercharged”
- “no sticky residue left”
- “serums work better”
Glass skin glow Often Mentioned
- “skin looks dewy”
- “immediate glass skin”
- “glow lasts all day”
- “makeup sits better”
Time-consuming routine Often Mentioned
- “hard to stick to”
- “adds 10 mins to routine”
- “gave up after a month”
- “too much effort daily”
Improved texture Sometimes Noted
- “bumps smoothed out”
- “pores look smaller”
- “texture is softer”
- “makeup applies smoother”
Visible lifting Sometimes Noted
- “jawline looks snatched”
- “face feels tighter”
- “reduced morning puffiness”
- “cheekbones pop more”
High price point Sometimes Noted
- “very pricey investment”
- “gel is expensive”
- “not worth the full price”
- “wait for a sale”
Unpleasant sensation Sometimes Noted
- “zaps hurt sensitive areas”
- “teeth feel weird”
- “muscle twitching is creepy”
- “prickly sensation”
Potential irritation Rarely Noted
- “caused small bumps”
- “redness after use”
- “broke me out”
- “too harsh for sensitive skin”
Sources: lovi.care, medicube.us, amazon.com, youtube.com, reddit.com, cosmopolitan.com, and more
Questions and answers
How well does Mediheal AGE-R work for sensitive skin?
Mediheal AGE-R works for sensitive skin, though other treatments fit it better by being exceptionally well-suited and highly compatible. A treatment for this skin needs effective ingredients that calm redness and irritation, provide deep hydration, and protect against irritation while supporting overall skin health.
Clinical, Cosmetic and Investigational Dermatology, 2014Journal of the European Academy of Dermatology and Venereology, 2024
Which ingredients make this cream a good fit for sensitive skin?
Glutathione, collagen, and peptides help make this treatment a safe and moderate fit for your sensitive skin by offering soothing effects for redness and irritation while avoiding harsh ingredients. A treatment that fits this skin type even better needs powerful soothing ingredients, deep hydration, and helpful antioxidants like niacinamide or snail secretion filtrate to calm redness safely.
Clinical, Cosmetic and Investigational Dermatology, 2014Journal of the European Academy of Dermatology and Venereology, 2024
What does Glutathione do for sensitive skin?
Glutathione helps calm sensitive skin by reducing oxidative stress and protecting against environmental irritation. It is unlikely to cause irritation and has a very safe profile when used on the skin.
Journal of the European Academy of Dermatology and Venereology, 2024Indian Journal of Dermatology, Venereology and Leprology, 2016
What does Collagen do for sensitive skin?
Collagen helps soothe sensitive skin by reducing dryness, redness, and rough patches while keeping moisture locked in. It improves the skin barrier so it is less easily irritated, and studies show it is well tolerated and safe for sensitive skin types.
International Journal of Cosmetic Science, 2009Pharmaceutical Development and Technology, 2014
Where does this cream go in a skincare routine for sensitive skin?
This treatment goes in your evening routine, applied after your cleanser and soothing toner and before your moisturizer. It is safe for your sensitive skin because it lacks harsh ingredients, though a product of this type for your skin needs soothing ingredients and gentle hydrators to keep redness calm and soft.
Can I use it with retinol, and in what order?
You can use this treatment with retinol in your evening routine, but this product may only be an average fit for your sensitive skin. To truly feel comfortable and smooth while using both, this skin needs gentle, fragrance-free hydrating ingredients and soothing plant extracts that calm redness without harsh actives.
How often should I use this cream?
You can use this treatment in the evening as part of your routine. Sensitive skin needs a product of this type that features gentle soothing ingredients and lacks harsh components to keep redness calm and comfortable.
Clinical, Cosmetic and Investigational Dermatology, 2014Journal of the European Academy of Dermatology and Venereology, 2024
Can it clog pores, cause breakouts or purging for sensitive skin?
This treatment is unlikely to clog pores or cause breakouts on sensitive skin as it lacks harsh or prohibited ingredients. However, it may cause mild irritation for some users since a few reviewers report an unpleasant sensation.
What the research says
Both oral and topical collagen supplements help delay the skin aging process by improving moisture, elasticity, and hydration, with no differences arising between the two types of collagen.
Dermatology Practical & Conceptual, 2022The use of cosmetic products containing collagen or its peptides improves the general condition of the skin, reduces wrinkle depth, improves hydration and density, reduces transepithelial water loss, and delays the aging process, while oral bioactive collagen peptides also reduce nail breakage.
Current Issues in Molecular Biology, 2024Topical oxidized glutathione significantly decreases the skin melanin index and improves moisture content, smoothness, wrinkle formation, and elasticity compared to placebo in healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2014Glutathione amino acid precursors effectively increase cellular glutathione levels, reducing oxidative stress, ATP depletion, and DNA damage in human keratinocytes, clinical subjects, and ex vivo skin compared to controls.
Journal of the European Academy of Dermatology and Venereology, 2024Glutathione at 500 mg/day orally or 2.0% topically may brighten skin color in sun-exposed areas measured by melanin index, though current evidence remains inconclusive.
Journal of Cosmetic Dermatology, 2019Topical glutathione improves hyperpigmentation, reduces ultraviolet-induced erythema and wrinkles, decreases transepidermal water loss, and enhances antioxidant capacity.
The Journal of Clinical and Aesthetic Dermatology, 2025RayGel reduced skin reaction severity with a lower average score of 93.7 compared to 123.3 for the placebo group in patients undergoing whole breast external-beam irradiation.
American Journal of Surgery, 2005Combining high-intensity focused ultrasound with a topical agent containing glutathione and hyaluronic acid significantly improves skin quality, fine wrinkles, hyperpigmentation, hydration, and brightness in female volunteers compared to the topical agent alone.
The Journal of Dermatological Treatment, 2024Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris.
Journal of Cosmetic Dermatology, 2022Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks.
International Journal of Molecular Sciences, 2022Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers.
Marine Drugs, 2023
Ingredients
Glutathione, Collagen, Peptides
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
Scan your face, then any product: Lovi shows how well it fits you and what fits even better.